Dmel014610.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila melanogaster
Gene Symbol
-
Assembly
GCA_000001215.4
Location
JANZWZ010000387.1:193633-199935[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.6e-05 0.0017 19.0 2.1 1 23 212 234 212 234 0.97
2 16 5.2e-06 0.00057 20.5 0.4 1 23 240 262 240 262 0.97
3 16 0.00077 0.084 13.7 0.9 1 23 268 290 268 290 0.95
4 16 1.1e-05 0.0012 19.5 3.1 1 23 296 318 296 318 0.97
5 16 2.5e-05 0.0027 18.3 4.7 1 23 324 346 324 346 0.99
6 16 4.6e-05 0.005 17.5 5.7 1 23 352 374 352 374 0.97
7 16 2.2e-07 2.5e-05 24.8 4.3 1 23 380 402 380 402 0.98
8 16 8.1e-08 8.8e-06 26.2 2.4 1 23 408 430 408 430 0.97
9 16 4.7e-05 0.0051 17.5 6.7 1 23 437 459 437 459 0.97
10 16 8.2e-05 0.0089 16.7 6.5 1 23 465 487 465 487 0.98
11 16 7.3e-06 0.0008 20.0 4.5 1 23 493 515 493 515 0.98
12 16 5.3e-06 0.00058 20.5 8.1 1 23 521 543 521 543 0.98
13 16 1.3e-05 0.0014 19.2 3.8 1 19 549 567 549 568 0.96
14 16 0.011 1.2 10.0 0.4 4 23 567 586 567 586 0.95
15 16 0.00058 0.064 14.0 3.4 1 23 596 618 596 618 0.97
16 16 6.6e-06 0.00073 20.2 1.6 1 23 624 647 624 647 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCAGTAGTAACTCCTGTTGTGACCACTGGTGGGACAACGATCACATTGGGCGGCCCACCACCGCTCCCTAAATCCGAGCACAAAGAGGATGGCAAGCCGCCGCACGGCATCGAAATGTACAAGGTGAACATTGAGGACATTTCGCAGCTCTTCACCTACCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTCAATCATCAATTAGCAGCGGCCCACGGCGGCCAGTTGCCACCACCTCCTCCGCTGCCGCCGCAGGTTACCAGTCATGCGGCGAGtgcagcggcagccgcagcagcggccggtaatggcatcagcgaatgcagcagcggccgcggcggcagctgcatcGGCGGGGGAGGACTACCGCCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTGACGACGACCAGCAGCTCGACTAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTggacggcagcggcaatggcggcaatggtggcggacaaaacgtggcgctggcgccagacggtacgcccattgcgacggggacgcacgtctgcgacatctgcggcaagatgttccagttccggtaccagctgatcgtgcaccggcgctaccacagcgaacggaagccgttcatgtgccaggtgtgcggccaggggttcaccacgtcgcaggatttgacgcgccacggcaagatccatattggcgggcccatgttcacctgcatcgtgtgcttcaatgtgttcgcgaacaatacgagcctggagcggcacatgaaacggcactcgacggacaaaccgttcgcctgcaccatttgccaaaagacctttgcccgcaaagagcatctggacaatcacttccgctcgcacacgggcgaaacgcccttccgttgccagtactgcgccaagacgttcacgcgcaaggagcacatggtcaaccatgtgcgcaaacacacgggtgagacgccacatcgttgcgatatttgtaagaagtcctttacgcgcaaggaacactatgttaaccactacatgtggcacactggtcaaacgccgcaccagtgcgatgtctgcggcaagaaatatacgcgcaaggagcacctagccaatcatatgcgatcccataccaacgagacgccgttccgttgcgagatctgcggcaagagctttagccgcaaggagcacttcaccaatcacatactttggcatacagcaggcgagacgccgcaccggtgcgacttttgctccaagacgtttacgcgcaaggagcacttgcttaaccacgtgcgccagcatacgggagagtcgccacaccgctgctcctactgcatgaagacgttcacgcgcaaggagcacctggtcaaccacatacgccagcacacgggtgagacaccgttcaagtgcacgtactgcacgaaagcgttcacgcgcaaagatcacatggttaatcatgtacggcaacatacaggcgagtcgccgcacaagtgcacgtactgcaccaagacgttcacgcgcaaggagcacctgacgaaccatgtgcgccagcacacgggcgactccccgcaccgctgctcctactgcaagaagaccttcacgcgcaaggagcacctgacgaaccatacgtgcggcaaatcgttcccgctcaagggcaatctgctcttccatcagcgcagccataccaagggccaggagatggagcggccattcgcctgcgagaagtgccccaagaacttcatctgcaaAGgtcacttggtctcgcacatgcgctcccattcgggtgagaaaccacacgcgtgcacactgtgcagcaaggcgttcgtcgagcgcggcaatttgaagcgccacatgAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTATGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACCACCACAATGCACACCATTCAgcagatcacggcgggtgcggcgggcggagccggtgcggtccagttaacaccgggtctgcagtcgcagaagcagcaagcagccgccgcagcagctgcacagcaacaggccgcagccgccgctgctgcccaacagcaagcagctcagcaacaggcggctgctgcacatcagcagcatcaacaacaagtggccgcgcaacatcaacagcaggctgcagtggctgcacaccagcagcagcaacagcagttgcagcagcagcaacaactgcttcagttgtccatccaacaggcggctcaccatcatcagcaggagcagcatcgtcaacagcagcaacagcaacaccagcagcaacaacagcagcagcatcaccagcagcaacagcagggtcatccacaggccccgccaccgcagcagcaacagcagccgccgcccatcgccttgatcagtgacccaagtgctctggcacgtgccgccatccagctgcagcatctgccagcgaacgtggaacagcacccggttgtttactaa
Protein Sequence
MQHVSAASSVPSVVTPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQVTSHAASAAAAAAAAGNGISECSSGRGGSCIGGGGLPPATSGNGGQQVTVTTTSSSTSSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGNGGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHTCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGMLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLQSQKQQAAAAAAAQQQAAAAAAAQQQAAQQQAAAAHQQHQQQVAAQHQQQAAVAAHQQQQQQLQQQQQLLQLSIQQAAHHHQQEQHRQQQQQQHQQQQQQQHHQQQQQGHPQAPPPQQQQQPPPIALISDPSALARAAIQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00505532;
90% Identity
-
80% Identity
-