Dbir009956.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila birchii
Gene Symbol
-
Assembly
GCA_008042755.1
Location
VNKA01001287.1:4047-10471[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.7e-05 0.0014 19.0 2.1 1 23 222 244 222 244 0.97
2 18 5.7e-06 0.00046 20.6 0.4 1 23 250 272 250 272 0.97
3 18 0.00084 0.068 13.7 0.9 1 23 278 300 278 300 0.95
4 18 1.2e-05 0.00098 19.5 3.1 1 23 306 328 306 328 0.97
5 18 2.7e-05 0.0022 18.4 4.7 1 23 334 356 334 356 0.99
6 18 5e-05 0.0041 17.6 5.7 1 23 362 384 362 384 0.97
7 18 2.5e-07 2e-05 24.9 4.3 1 23 390 412 390 412 0.98
8 18 8.8e-08 7.1e-06 26.3 2.4 1 23 418 440 418 440 0.97
9 18 5.1e-05 0.0042 17.6 6.7 1 23 447 469 447 469 0.97
10 18 8.9e-05 0.0072 16.8 6.5 1 23 475 497 475 497 0.98
11 18 8e-06 0.00065 20.1 4.5 1 23 503 525 503 525 0.98
12 18 5.8e-06 0.00047 20.5 8.1 1 23 531 553 531 553 0.98
13 18 4.7e-06 0.00038 20.8 7.6 1 23 559 581 559 581 0.97
14 18 5.3e-07 4.3e-05 23.8 7.7 1 23 587 609 587 609 0.98
15 18 0.00016 0.013 16.0 9.5 1 23 615 638 615 638 0.95
16 18 5.8e-05 0.0047 17.4 0.9 1 23 644 666 644 666 0.98
17 18 0.00064 0.052 14.1 3.4 1 23 676 698 676 698 0.97
18 18 7.3e-06 0.00059 20.2 1.6 1 23 704 727 704 727 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCAGTTGTAGCCCCCGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGACCACCACCGCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATTGAGATGTACAAGGTTAACATCGAGGACATCTCCCAGCTCTTTACCTATCACGAGGTCTTTGGCAAGATCCATGGCGATGTTGTGAATCATCAATTGGCGGCGGCCCATGGAGGCCAgctgccaccaccgccgccccTTCCACCGCAGGCCACTAGTCATGCGGCCAgcgcggcagcagcagccgcagcagcgtcCACAAATAATGCCGCTGTGGCGGCGGTGATGGCCTCCGCcaatgcggcggcggcggcagcagcggctgcatCAGCAGCGGGCGGACTACCGCCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTAACGACGACCAGCAGCTCGACGGCCAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGGCAatggcggcggcaacggcggGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCAATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTATCAGCTGATCGTTCACCGGCGCTACCACAGCGAACGGAAACCGTTCATGTGCCAGGTGTGTGGCCAGGGCTTCACCACGTCGCAGGATTTGACCCGACACGGCAAGATACACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCGAATAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGATAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTGAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGgTCAAACGCCGCACCAGTGTGATGTCTGCGGCAAGAAATATACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCATATACTCTGGCACACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGCTTAACCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTTACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCATCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCATACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTTACGCGGAAGGAGCATCTCAACAACCATATGCGTCAGCATTCAAGCGACAATCCGCACTGCTGCAATGTCTGCAATAAGCCGTTTACGCGCAAGGAGCACCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGGCCCTTCACCTGCGAGACATGCGGCAAATCGTTCCCGCTCAAGGGTAACCTGCTCTTCCATCAGCGTAGCCACACCAAGGGCCAGGAGATGGAGCGGCCATTTGCCTGCGAGAAGTGCCCCAAGAATTTCATTTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCATTCGGCGACCACCACGATGCACACCATCCAGCAGATAACCGCTGGTGCGGCGggcggtgccggtgccgtGCAGCTAACACCGGGCCTGGTGCCCCTGCCGCCACCAGGAGTGCCCATCGCCTTGATAAGTGATCCCAGTGCTTTGGCCCGCGCCGCcatgcagctgcagcatctGCCAGCGAACGTGGAGCAACACCCGGTTGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGLPPATSGNGGQQVTVTTTSSSTASSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLPPPGVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00505532;
90% Identity
iTF_00507738;
80% Identity
-