Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: CM074800.1:42672293-42678373[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.3e-05 0.0019 18.8 2.1 1 23 215 237 215 237 0.97

2 18 7.7e-06 0.00064 20.4 0.4 1 23 243 265 243 265 0.97

3 18 0.0011 0.094 13.5 0.9 1 23 271 293 271 293 0.95

4 18 1.6e-05 0.0013 19.3 3.1 1 23 299 321 299 321 0.97

5 18 3.7e-05 0.0031 18.2 4.7 1 23 327 349 327 349 0.99

6 18 6.7e-05 0.0056 17.4 5.7 1 23 355 377 355 377 0.97

7 18 3.3e-07 2.7e-05 24.6 4.3 1 23 383 405 383 405 0.98

8 18 1.2e-07 9.8e-06 26.1 2.4 1 23 411 433 411 433 0.97

9 18 6.9e-05 0.0057 17.3 6.7 1 23 440 462 440 462 0.97

10 18 0.00012 0.01 16.6 6.5 1 23 468 490 468 490 0.98

11 18 1.1e-05 0.00089 19.9 4.5 1 23 496 518 496 518 0.98

12 18 7.8e-06 0.00065 20.3 8.1 1 23 524 546 524 546 0.98

13 18 6.3e-06 0.00053 20.6 7.6 1 23 552 574 552 574 0.97

14 18 7.1e-07 5.9e-05 23.6 7.7 1 23 580 602 580 602 0.98

15 18 0.00022 0.018 15.8 9.5 1 23 608 631 608 631 0.95

16 18 7.8e-05 0.0065 17.2 0.9 1 23 637 659 637 659 0.98

17 18 0.00083 0.069 13.9 4.4 1 23 669 691 669 691 0.98

18 18 9.8e-06 0.00081 20.0 1.6 1 23 697 720 697 720 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.3e-05	0.0019	18.8	2.1	1	23	215	237	215	237	0.97
2	18	7.7e-06	0.00064	20.4	0.4	1	23	243	265	243	265	0.97
3	18	0.0011	0.094	13.5	0.9	1	23	271	293	271	293	0.95
4	18	1.6e-05	0.0013	19.3	3.1	1	23	299	321	299	321	0.97
5	18	3.7e-05	0.0031	18.2	4.7	1	23	327	349	327	349	0.99
6	18	6.7e-05	0.0056	17.4	5.7	1	23	355	377	355	377	0.97
7	18	3.3e-07	2.7e-05	24.6	4.3	1	23	383	405	383	405	0.98
8	18	1.2e-07	9.8e-06	26.1	2.4	1	23	411	433	411	433	0.97
9	18	6.9e-05	0.0057	17.3	6.7	1	23	440	462	440	462	0.97
10	18	0.00012	0.01	16.6	6.5	1	23	468	490	468	490	0.98
11	18	1.1e-05	0.00089	19.9	4.5	1	23	496	518	496	518	0.98
12	18	7.8e-06	0.00065	20.3	8.1	1	23	524	546	524	546	0.98
13	18	6.3e-06	0.00053	20.6	7.6	1	23	552	574	552	574	0.97
14	18	7.1e-07	5.9e-05	23.6	7.7	1	23	580	602	580	602	0.98
15	18	0.00022	0.018	15.8	9.5	1	23	608	631	608	631	0.95
16	18	7.8e-05	0.0065	17.2	0.9	1	23	637	659	637	659	0.98
17	18	0.00083	0.069	13.9	4.4	1	23	669	691	669	691	0.98
18	18	9.8e-06	0.00081	20.0	1.6	1	23	697	720	697	720	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCTAGCTCGGTGCCATCAGTTGTAGCCCCGGTCGTGACCACTGGTGGAACCACCATCACCCTCGGCGGACCGCCGCCCTTGCCCAAATCTGAACACAAAGAGGATGGCAAACCGCCGCACGGCATAGAAATGTACAAGGTGAACATTGAGGATATCTCCCAGCTGTTTACGTACCACGAGGTCTTTGGCAAGATCCACGGCGATGTGGTCAATCATCAGCTGGCGGCGGCGCATGGCGGACAAttgccgccaccaccacccctGCCACCGCAGACGCATGCCGTgagcgcagcggcagcggcggctgcagcatcCACCAATAATGCCGCTGTGGCGGCTGTAATGGCCTCAGCgaatgctgctgcagcggcagcggcggccgcCTCGGCGGCGGGAGGCAACGGCCTGCCGGCGGCCACGAGCTCCGGCGGCCAGCAGGGCAGCGCTACGGTGACCACGACCAGTTCGACGGcgagcagtggcagcggcggcagcggtaGCGGGGGCACCACAACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGGCAGTCGACCGTGGCGCTGGCCCCAGACGGGACGCCCATTGCGACGGGGACCCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGGTATCAGCTGATCGTGCACCGTCGCTACCACAGCGAACGCAAGCCGTTTATGTGTCAGGTGTGCGGACAGGGTTTCACCACGTCACAGGACCTGACACGCCATGGGAAGATCCACATCGGTGGCCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTTGCCAACAACACCAGTCTGGAGCGGCATATGAAACGTCATTCCACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGCTCGCACACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTCACGCGCAAGGAGCATATGGTTAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTATGCGGCAAGAAATACACGCGCAAGGAGCATCTAGCAAATCATATGCGATCGCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAATCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTCACGCGCAAGGAGCACCTAACGAACCATGTGCGTCAGCACACGGGCGACTCGCCGCACCGTTGCTCCTACTGCAAGAAGACCTTCACACGGAAGGAGCACCTGACGAACCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTCACACGGAAGGAGCACCTCAACAACCATATGCGCCAGCATTCAAGCGACAATCCGCACTGCTGCAACGTTTGCAACAAGCCGTTCACCCGCAAGGAGCATCTGATCAATCACATGTCGCGCTGCCACACCGGCGATCGACCCTTCACCTGCGAGACATGCGGCAAATCGTTCCCACTCAAGGGCAACCTGCTCTTCCATCAGCGCAGCCACACCAAGGGCCAAGAGATGGAGCGTCCGTTCTCCTGCGAGAAGTGCCCCAAGAACTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCACACGCGTGCACTCTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCCACCACGATGCACACCATCCAGCAGATCACGGCCGGTGCCGCCAGCGGAGCGGGTGCGGTCCAACTGACGCCGGGTCTGGTGCCGCTGGTCACCTCCACGCTGATTTCGCATAACGCTGCcgcccagcagcagtcgcagaaGCAGCAGGCCGCCCAGCAACAGgcggccgctgcagcggctgcccagcagcaagcagccgcccagcagcaggcagcggcggcccatcagcagcatcagcaacaggtGGCGgctcagcatcagcagcaggcggtggccgcccaccagcaacagcagcagcagctccaacagcagcaactgctGCAGCTCTCGATCCAGCAGGCTGCccatcaccatcagcagcaggagcagcaccgccagcagcagcatcaacagcagcagcagcaacaccatcaacagcaacagcagggcCACCCGCAGGCGCCCCCAccgccgcaacagcagcagcagccgccgccacagGTGCCCATCGCCCTGATCAGCGATCCCAGTGCCTTGGCCCGTGCTGCcatgcagctgcagcattTGCCGGCCAACGTAGAACAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQTHAVSAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGNGLPAATSSGGQQGSATVTTTSSTASSGSGGSGSGGTTTTAGELLMPKMEGGIHGVDGQSTVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTMHTIQQITAGAASGAGAVQLTPGLVPLVTSTLISHNAAAQQQSQKQQAAQQQAAAAAAAQQQAAAQQQAAAAHQQHQQQVAAQHQQQAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQQEQHRQQQHQQQQQQHHQQQQQGHPQAPPPPQQQQQPPPQVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505532;
90% Identity: iTF_00336928;
80% Identity: -