Dfic000323.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ficusphila
Gene Symbol
-
Assembly
GCA_018152265.1
Location
JAECXK010000595.1:1630549-1637010[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.6e-05 0.0011 19.1 2.1 1 23 220 242 220 242 0.97
2 18 5.3e-06 0.00038 20.6 0.4 1 23 248 270 248 270 0.97
3 18 0.00078 0.056 13.8 0.9 1 23 276 298 276 298 0.95
4 18 1.1e-05 0.0008 19.6 3.1 1 23 304 326 304 326 0.97
5 18 2.6e-05 0.0018 18.5 4.7 1 23 332 354 332 354 0.99
6 18 4.7e-05 0.0033 17.6 5.7 1 23 360 382 360 382 0.97
7 18 2.3e-07 1.6e-05 24.9 4.3 1 23 388 410 388 410 0.98
8 18 8.2e-08 5.8e-06 26.3 2.4 1 23 416 438 416 438 0.97
9 18 4.8e-05 0.0034 17.6 6.7 1 23 445 467 445 467 0.97
10 18 8.3e-05 0.0059 16.8 6.5 1 23 473 495 473 495 0.98
11 18 7.5e-06 0.00053 20.1 4.5 1 23 501 523 501 523 0.98
12 18 5.4e-06 0.00038 20.6 8.1 1 23 529 551 529 551 0.98
13 18 4.4e-06 0.00031 20.9 7.6 1 23 557 579 557 579 0.97
14 18 4.9e-07 3.5e-05 23.9 7.7 1 23 585 607 585 607 0.98
15 18 0.00015 0.011 16.0 9.5 1 23 613 636 613 636 0.95
16 18 5.5e-05 0.0039 17.4 0.9 1 23 642 664 642 664 0.98
17 18 0.0006 0.042 14.2 3.4 1 23 674 696 674 696 0.97
18 18 6.8e-06 0.00048 20.3 1.6 1 23 702 725 702 725 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCGGTAGTAGCCCCTGTAGTGACCACTGGTGGGACGACTATCACCTTGGGCGGCCCACCGCCCCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATCGAAATGTATAAGGTGAACATCGAGGACATCTCGCAGCTCTTCACCTACCACGAGGTCTTTGGCAAGATCCACGGCGATGTGGTCAATCATCAGTTGGCGGCGGCCCACGGCGGCCAGCTGCCACCACCTCCGCCGCTGCCGCCGCAGGTCACCAGTCATGCGGCAAGTGCGGCGGCAGCCGCAGCAGCGGCTTCAACAAACAATGCGGCCGTGGCGGCGGTAATGGCCTCGGCGAATGCGGCAGCGGCCGCGGCGGCGGCCGCATCATCGGCGGGAGGACTGCCGCCGGCCACCAGTGGCAACGGGGGCCAACCGGTGACGGTGACGACGACGAGCAGCTCGACCAGCAGCGGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGAGGCATTCATGGCGTGGACGGCAGCGGCAATGGCAATGGCGGGCAGAACGTGGCGCTAGCGCCGGACGGTACGCCGATTGCGACGGGGACGCACGTCTGCGATATCTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAGCCGTTCATGTGCCAGGTGTGCGGCCAGGGGTTCACCACGTCGCAGGATTTGACGCGCCACGGCAAGATCCACATTGGCGGGCCGATGTTCACCTGCATCGTGTGCTTCAATGTGTTTGCGAACAACACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGCTCGCACACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTCACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGCGATGTCTGTGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGTGAGATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAACCACATCCTCTGGCACACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAACACTTGCTAAACCACGTGCGCCAGCACACGGGAGAGTCGCCGCACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACGTACTGCACTAAGACGTTCACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTCACGCGCAAGGAGCACCTGACGAACCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTCACGCGGAAGGAGCACCTCAACAACCACATGCGCCAGCACTCGAGCGACAATCCGCACTGCTGCAACGTCTGCAATAAGCCGTTCACGCGCAAGGAGCACCTGATCAACCATATGTCGCGCTGCCACACCGGCGACCGGCCCTTCACCTGCGAGACGTGCGGCAAGTCCTTTCCGCTCAAGGGCAACCTGCTCTTCCACCAGCGCAGCCACACCAAGGGCCAGGAGATGGAGCGGCCCTTCGCCTGCGAGAAGTGCCCCAAGAACTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCTCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCAGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAGATCACGGCGGGCGCGGCGGGTGGAGCCGGAGCAGTGCAGCTAACGCCGGGTCTGGTGCCCTTGCTGCAGCACTTGCCTGCGAACGTGGAGCAGCACCCGGTTGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQVTSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASSAGGLPPATSGNGGQPVTVTTTSSSTSSGGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLLQHLPANVEQHPVVY