Dvul026087.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila vulcana
Gene Symbol
-
Assembly
GCA_008042555.1
Location
VNJP01008889.1:212434-219511[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.4e-05 0.0018 19.2 2.1 1 23 227 249 227 249 0.97
2 16 4.5e-06 0.00061 20.7 0.4 1 23 255 277 255 277 0.97
3 16 0.00066 0.089 13.9 0.9 1 23 283 305 283 305 0.95
4 16 9.5e-06 0.0013 19.7 3.1 1 23 311 333 311 333 0.97
5 16 2.2e-05 0.0029 18.6 4.7 1 23 339 361 339 361 0.99
6 16 3.9e-05 0.0053 17.7 5.7 1 23 367 389 367 389 0.97
7 16 4e-05 0.0054 17.7 6.7 1 23 395 417 395 417 0.97
8 16 7e-05 0.0095 16.9 6.5 1 23 423 445 423 445 0.98
9 16 6.3e-06 0.00085 20.2 4.5 1 23 451 473 451 473 0.98
10 16 4.5e-06 0.00061 20.7 8.1 1 23 479 501 479 501 0.98
11 16 3.7e-06 0.0005 21.0 7.6 1 23 507 529 507 529 0.97
12 16 4.1e-07 5.6e-05 24.0 7.7 1 23 535 557 535 557 0.98
13 16 0.00013 0.017 16.1 9.5 1 23 563 586 563 586 0.95
14 16 4.6e-05 0.0062 17.5 0.9 1 23 592 614 592 614 0.98
15 16 0.0005 0.068 14.3 3.4 1 23 624 646 624 646 0.97
16 16 5.7e-06 0.00077 20.4 1.6 1 23 652 675 652 675 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCTAGCTCGGTGCCATCAGTTGTAGCCCCCGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGACCACCACCGCTCCCCAAATCGGAGCACAAAGAGGATGGCAAGCCGCCGCACGGCATTGAGATGTACAAGGTTAACATCGAGGACATCTCTCAGCTCTTCACCTATCACGAGGTCTTTGGCAAGATCCATGGCGATGTTGTGAATCATCAATTGGCGGCGGCCCATGGAGGGCAgctgccaccaccgccgcccctTCCACCGCAGGCCACTAGTCATGCGGCCAgtgcggcagcagcagccgcagcggcGTCCACAAATAATGCCGCTGTTGCGGCAGTGATGGCCTCCGCcaatgcggcggcggcggcagcagcggctgcatcggcagcgggcggcggcgggggaCTACCACCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTGACGACGACCAGCAGCTCGACGGCAAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCggcaatggcggcggcggcggcaacggcggGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCAATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAACCGTTCATGTGCCAGGTGTGTGGCCAGGGCTTCACCACATCGCAGGATTTGACGCGCCACGGCAAGATTCACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCGAACAATACGAGCCTGGAGCGGCACATGAAACGTCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGTGCGAAGACGTTTACGCGCAAGGAGCACATGGTGAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAACATTTGCTTAACCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACAAAGACGTTTACGCGCAAGGAACACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCATACGGGCGACTCGCCCCATAAGTGCGAGTACTGCCAGAAGACGTTTACGCGGAAGGAGCATCTCAACAACCATATGCGTCAGCATTCAAGCGACAATCCGCACTGTTGCAATGTCTGCAATAAGCCGTTTACGCGCAAGGAGCACCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGGCCCTTCACCTGCGAGACATGCGGCAAATCGTTCCCGCTCAAGGGTAACCTGCTTTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGATGGAGCGTCCGTTTGCCTGTGAGAAGTGCCCCAAGAATTTCATCTGCAaagGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGTGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCATCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAAATAACCGCTGGTGCGGCGGGCGGTGCCGGTGCCGTGCAGCTAACGCCGGGATTGctgccgccgccacagcGTCGACGCAAGCGGCGTGGTGAGATTATTGGGCAACAACCAGTGAGCTAG
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQQVTVTTTSSSTASSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGGGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLLPPPQRRRKRRGEIIGQQPVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00529689;
90% Identity
iTF_00507738;
80% Identity
-