Dtak009381.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila takahashii
Gene Symbol
-
Assembly
GCA_018152695.1
Location
JAECXN010000003.1:19188064-19194437[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.7e-05 0.0011 19.2 2.1 1 23 228 250 228 250 0.97
2 18 5.6e-06 0.00035 20.7 0.4 1 23 256 278 256 278 0.97
3 18 0.00083 0.051 13.9 0.9 1 23 284 306 284 306 0.95
4 18 1.2e-05 0.00073 19.6 3.1 1 23 312 334 312 334 0.97
5 18 2.7e-05 0.0017 18.5 4.7 1 23 340 362 340 362 0.99
6 18 4.9e-05 0.003 17.7 5.7 1 23 368 390 368 390 0.97
7 18 2.4e-07 1.5e-05 25.0 4.3 1 23 396 418 396 418 0.98
8 18 8.7e-08 5.3e-06 26.4 2.4 1 23 424 446 424 446 0.97
9 18 5.1e-05 0.0031 17.7 6.7 1 23 453 475 453 475 0.97
10 18 8.8e-05 0.0054 16.9 6.5 1 23 481 503 481 503 0.98
11 18 7.9e-06 0.00048 20.2 4.5 1 23 509 531 509 531 0.98
12 18 5.7e-06 0.00035 20.7 8.1 1 23 537 559 537 559 0.98
13 18 4.6e-06 0.00029 20.9 7.6 1 23 565 587 565 587 0.97
14 18 5.2e-07 3.2e-05 23.9 7.7 1 23 593 615 593 615 0.98
15 18 0.00016 0.01 16.1 9.5 1 23 621 644 621 644 0.95
16 18 5.7e-05 0.0035 17.5 0.9 1 23 650 672 650 672 0.98
17 18 0.00063 0.039 14.2 3.4 1 23 682 704 682 704 0.97
18 18 7.2e-06 0.00044 20.3 1.6 1 23 710 733 710 733 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCTAGCTCGGTGCCATCAGTAGTAGCCCCTGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGCCCACCGCCGCTCCCCAAATCGGAGCACAAAGAGGATGGCAAGCCGCCGCACGGCATCGAGATGTACAAGGTGAACATCGAGGATATTTCGCAGCTCTTTACCTACCACGAGGTCTTTGGCAAGATCCACGGCGATGTGGTCAATCATCAATTGGCGGCGGCCCACGGTGGGCAATTGCCACCACCTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGACGGTAACGACGACCAGCAGCTCGACAAGCAGCGGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTAATGCCTAAAATGGAGGGCGGCATACATGGCGTGGACGGCAGCGGCAATGGCGGCAATGGCGGCGGGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCCATTGCGACGGGGACGCATGTCTGCGATATCTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAGCCGTTCATGTGCCAGGTGTGCGGCCAGGGCTTCACAACATCGCAGGATTTGACGCGCCACGGCAAGATCCATATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCGAACAATACGAGCCTGGAGCGGCACATGAAGAGGCACTCAACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTCCGCTCGCACACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTCACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCCCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGATCGCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGTGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCACTTGCTAAACCACGTGCGCCAGCACACGGGAGAGTCGCCGCACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACGTACTGCACCAAGACGTTCACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCATTTGACGAACCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTTACGAGGAAGGAGCACCTCAACAATCACATGCGCCAGCACTCGAGCGACAATCCGCATTGCTGCAACGTTTGCAACAAGCCGTTTACGCGCAAGGAGCACCTGATCAATCATATGTCGCGGTGCCACACCGGCGACCGTCCCTTCACCTGCGAGACGTGCGGCAAGTCGTTCCCGCTCAAGGGCAACCTGCTCTTCCATCAGCGCAGCCACACGAAGGGCCAGGAGATGGAGCGACCCTTTGCCTGCGAGAAGTGCCCCAAGAACTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGTGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCATCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAAGTGAGTCGGCAAACACACGACTGCGCTAG
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVTVTTTSSSTSSGGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGNGGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIISESANTRLR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00478871;
90% Identity
iTF_00507738;
80% Identity
-