Dmim015710.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mimetica
Gene Symbol
-
Assembly
GCA_037075245.1
Location
JBAMCH010000023.1:8604947-8608413[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00029 0.022 15.3 0.9 2 23 179 201 179 201 0.96
2 16 0.0017 0.13 12.9 2.6 1 23 216 239 216 239 0.96
3 16 0.0032 0.25 12.1 3.7 1 23 310 333 310 333 0.96
4 16 0.0036 0.28 11.9 0.7 2 23 388 409 387 409 0.96
5 16 9.8 7.6e+02 1.1 1.0 1 20 524 542 524 544 0.74
6 16 0.019 1.5 9.6 0.6 1 23 554 576 554 576 0.94
7 16 0.00026 0.02 15.5 0.7 1 23 583 606 583 606 0.96
8 16 0.00018 0.014 16.0 0.5 2 23 615 636 614 636 0.96
9 16 0.0009 0.069 13.8 0.1 2 22 663 683 662 686 0.90
10 16 0.0014 0.1 13.2 1.2 1 23 720 743 720 743 0.96
11 16 6.6 5.1e+02 1.6 1.8 1 22 750 771 750 771 0.94
12 16 0.0067 0.52 11.0 0.4 1 23 780 803 780 803 0.97
13 16 2.7e-06 0.00021 21.7 0.5 1 23 824 847 824 847 0.97
14 16 0.037 2.8 8.7 0.2 1 23 857 879 857 879 0.94
15 16 6.3e-05 0.0048 17.4 3.7 1 23 885 907 885 907 0.99
16 16 6.1e-05 0.0047 17.5 1.0 1 23 913 935 913 935 0.97

Sequence Information

Coding Sequence
ATGACGCGGACTTGTAGGATATGTGGCGGCGACGACGGTCGCTACTGGATTGAGACGCCCGTGGAGAAGTACGCCGAGAAGACCTTCGGGCAGCTGCTGCTCGAGCTAACGCACATCGAGGTGGCTATGGCGCAGGCTGAGAAGTTCCCACAATGGCTGTGCAACGCGTGTGCCGAGAAGCTGGAGAGCACCTATGACTTTGTGCTGCAGGCGCGCCAGACGCACGAACTGTGGGTGCAGAAACTCGGGGACTCCGTGGACGGAGATGACCAAATGGAGGGCACAGGCACCGAGGCCTTGGAGTGCCTTCGCGAGACACCCATTCACCTGTTCGAAATCGAGGGCGTCACCATCAAGACCGAGGATCTAGCTCCCACGCAGCAAGCGGCCAAGGCAGATCCTCTAGTGCGCACGCGCTTCGTCAAGCGGAGCATCGTGCACTTTAGCGACTCGGATGACGACCAGGACGATGTGCCCCTGCGGCAGCGCAAGATCACCTCCTCGCTCTGCGCCTCGGAGCCGCCAAAGCCGAATGTTTGCGAGCTGTGCAACAAGGCCTTTAGATATGTCACCAATTTGTATCGCCACAAGCAGAGGGATCACGGCATTCTGGGCAAAAATGGAGAAGACTATGATGACGACTACTACAAGTGCGATCAGTGCGACAAAACCTACAAGTATGTGATGGCACTGGTGAAGCACAAGCACAGCGAGCACGGAGCCAGTCTCCTGCCCTCCAAAACCTCCAGGCGAAAGTTACCCGGCAGGCCGTCGACATTGCCTGAGGATGCCAATCCATCTAGTCCAGCCTCCACCTCCGGAAACTCCACACATCGAAGCAGGACCAACAACGACACCCTGGTGCATAGCATCATCAAGGCAGTGGAGCTGTCGGATGAGGAGGGCAACAGCAGCACAGACAACTACTACAAGTGCGATCAGTGCAGCAAGTCCTACAAGTACATAGTCAGCTTGATCAAGCACAAGCACAAGGAGCACTCTGACAAACAGTCGGACAAGCAGTCGGAGACCGAGGACGATCAGCCACTGGCCTCCACATCGGCCTCGGCAGTTCCACCAGCCGCCAAGCCATCCAGGATCAACCGAAGAGTCGACGACTTTGACTCCCATCGCTGCGAGCCAAATGGCGCCAAGGAAATCAAGTGTATGATCTGCTTGCGACGGTTCACCAAACTGCGTGAGCTAAGGGATCACCTGCAGGCTCATCCCACTGACTTTGGCTTCGAGGCGCACGGCGAGCCCATTGAGCGGATTGCGGAGGGATTTTTCAAGACTGCCGTGGAGTCCACTGCGGAGGGCTTGAAGCGGCGAATCTTTCGGGATCTCAGGATGGGCGTGTATGGCCGCTACTACTCCATCACCAATCAAGCTCGCTACGAGATGACCCTGGACAGCTCGGATACGGACAGTGATGGCGATGGTGAATCGGATGTCGTTATCAGAAGAAGCTATTCCTGCGAGCTGTGCGACTCTCCGGAGGCTAGGTGGCCGAGAAAGTACCTACTGCACCTGCACCACCGAAACGAGCACACCTGGCTGGATGCGCCACATGTCTGCCAGCGTTGCGACTCGAGGTTTCTCAGTGCTCAACTCCTGGACCACCACACCAGCCAGCTGTGCCAGAACACTCTGAAGCGCTTTATGTGCGACAAGTGCCCTCAGCGATTCTTTTGGCGCCGGAATCTGCGCGCCCATCTCGTCGAACACAAGAGCAAGCAAGAGACCTACCCCTGCGACCAATGCTCCCGCAGCTTTCAGGACAAGAGTGCCGTGACCAAGCACAAGCTGATGATGCACCGGGATAGTAGCATGCAGCTCCTTCCCTGCCGCTGGTGCACTCGCACCTTCTACCGCCCCGCCCTGTTGTACAAGCACCTGCAAAGGCACGGTTTCACTGGTCAGGATTTGCCACTGGCGGAAACTCTGCTCGCGGATGCCTCAAAGCCGGCCGGACCGAAGAGCATCCAGTGCAAAATGTGTGACATACAATTCATCAGCGTGGCGGATTTGCGAAGACACATATCAATACAGGGCCACAGCGATCAGCCATCGGCCTACATGATCAGCACTGCAACGGGCTttgagctgctgctggaggataCGGATGACAGCGATGAGGAAAGCACGGGGAGGTCGTACACTTGCGATCTTTGTGATCTGAACTTCCGGCGACGACGGGAAATGAGTGAGCACCAGTACTCACTGCATAGCTTCGACAAACTACCACATTCCTGCGAGCATTGCATTTTCAAGACAGTGGATAAGTTCATGCTTGATCAACACCTTCGCACCCAGTGTATGAACACCGAGAAGAAGTTTGTCTGCTCGCGCTGTGGCTACAAGTTCATGTGGGAGGAGAACCTGACGCAGCACCTAGCCACCCAGCATCCCAAGCAACCCACCGTTCCGGAGCAGCAGCCTCCGTTGAGGAGAAAGCGCCGCTTCCGCTACCAGTGTCCCCACTGCTGGCGCTCGTTTGTCGTGCAGCCCAGCCTGGAGAAGCACATCCGGGACATGCATGTGGCCAAGAAGAATCCGGGAAAGAAGTACCTCTGCTCGCTGTGCGGTCTGGAGTCGCTGACGCCCAACAAGCTGAACATCCATATGCGGCGACACATGGGCGAGAAGCCCTTCAAGTGTGATCTCTGCGACATGCGCTTCACGGTTCACTACGAACTGAAGGTTCACCGCCGGAAACACACCGGTGAGAGACCCTATCAATGCACCTTCTGCGCCAAGGACTTTGCGCGACCGGACAAATTGCGGCGGCATGTATTTATGCACAACGTCAAGTCATAG
Protein Sequence
MTRTCRICGGDDGRYWIETPVEKYAEKTFGQLLLELTHIEVAMAQAEKFPQWLCNACAEKLESTYDFVLQARQTHELWVQKLGDSVDGDDQMEGTGTEALECLRETPIHLFEIEGVTIKTEDLAPTQQAAKADPLVRTRFVKRSIVHFSDSDDDQDDVPLRQRKITSSLCASEPPKPNVCELCNKAFRYVTNLYRHKQRDHGILGKNGEDYDDDYYKCDQCDKTYKYVMALVKHKHSEHGASLLPSKTSRRKLPGRPSTLPEDANPSSPASTSGNSTHRSRTNNDTLVHSIIKAVELSDEEGNSSTDNYYKCDQCSKSYKYIVSLIKHKHKEHSDKQSDKQSETEDDQPLASTSASAVPPAAKPSRINRRVDDFDSHRCEPNGAKEIKCMICLRRFTKLRELRDHLQAHPTDFGFEAHGEPIERIAEGFFKTAVESTAEGLKRRIFRDLRMGVYGRYYSITNQARYEMTLDSSDTDSDGDGESDVVIRRSYSCELCDSPEARWPRKYLLHLHHRNEHTWLDAPHVCQRCDSRFLSAQLLDHHTSQLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKSKQETYPCDQCSRSFQDKSAVTKHKLMMHRDSSMQLLPCRWCTRTFYRPALLYKHLQRHGFTGQDLPLAETLLADASKPAGPKSIQCKMCDIQFISVADLRRHISIQGHSDQPSAYMISTATGFELLLEDTDDSDEESTGRSYTCDLCDLNFRRRREMSEHQYSLHSFDKLPHSCEHCIFKTVDKFMLDQHLRTQCMNTEKKFVCSRCGYKFMWEENLTQHLATQHPKQPTVPEQQPPLRRKRRFRYQCPHCWRSFVVQPSLEKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVFMHNVKS