Dmel016731.1
Basic Information
- Insect
- Drosophila melanogaster
- Gene Symbol
- -
- Assembly
- GCA_000001215.4
- Location
- JANZWZ010000297.1:2850-6225[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.00014 0.015 16.0 0.9 2 23 177 199 177 199 0.96 2 15 0.0016 0.18 12.6 2.7 1 23 214 237 214 237 0.96 3 15 0.0068 0.74 10.7 3.2 1 23 304 327 304 327 0.96 4 15 0.0014 0.15 12.9 1.4 2 23 382 403 381 403 0.97 5 15 4.4 4.9e+02 1.8 2.1 1 20 518 537 518 539 0.87 6 15 0.014 1.6 9.7 0.6 1 23 548 570 548 570 0.94 7 15 0.00019 0.021 15.6 0.7 1 23 577 600 577 600 0.96 8 15 0.00026 0.029 15.1 0.1 2 22 640 660 639 663 0.90 9 15 0.004 0.44 11.4 0.8 1 23 697 720 697 720 0.95 10 15 5 5.5e+02 1.7 3.3 1 22 727 748 727 748 0.94 11 15 0.082 8.9 7.3 0.3 1 23 757 780 757 780 0.95 12 15 1.2e-05 0.0013 19.4 0.5 1 23 801 824 801 824 0.97 13 15 2.1 2.3e+02 2.8 0.4 13 23 828 838 827 838 0.87 14 15 4.7e-05 0.0051 17.5 3.7 1 23 844 866 844 866 0.99 15 15 3.1e-06 0.00034 21.2 1.2 1 23 872 894 872 894 0.97
Sequence Information
- Coding Sequence
- ATGACCAGGACGTGCAGAGTGTGTGGCTGCGACGACGGACGCTACTGGATTGAAACGCCCGTGGAGAAGTACGCGGAGAAGACCTTCGTCCAGCTGCTGGTCGAGCTAACGCGAATCGAGGTGGTCATGGCGCAAGCTGAGAAGTTCCCACAGTGGCTGTGCTACGCGTGTGCCGAGAAGCTGGAGAGCACCTACGATTTTGTGCTGCAGGCACGTCGAACACACGAGCTGTGGCTGCAGAAAATCGGGGATTCTTTGAATGGGGATGACGAGATGGAGGGCACTGCGGCCTTGGAATGCCTGCGTGAGACACCCATCCACCTGTTTGAGATTGAAGGCGTGACCATCAAGACGGAGGAACTGGCTTCAACGCAACAGGCGCCCAAGGCAGATCCTTTAGTGCGCCCGCGCATTGTCAAACGGAGTATTGTACACTTTAGCGATTCCGATGAAGACCTGGATGATGTGCCTCTGCGTCAACGTAAGATAGCAGCCTCGGTCTGCGGCTCTGACACGACGAAGGAAAATGTTTGCGAGCTGTGCAACAAGGTCTTCAGATATGTCACCAATCTGTATCGTCACAAGCAGAGGGACCACGGAATTCTGGGCAAGAACGGAGAGGATTATGAAGAAGACTATTACAAGTGCGATCTGTGCGATAAAACCTACAAGTACGTGATGGCGCTGGTGAAGCACAAACACAAAGAGCACGGATCAGTCTCCTGTCGAATAATTCCGGGCGAAAGATGCCGTCAACTTTGGCCGAAGATGCCAATCCATACAGTCCAGCATCCATCTCTGAAACATCCACTAATCAAAAGCAGAACCAACAACGACTCCCTGGTACACAGCATCATCAAGGCAGTGGTACTCTCCGATGAGGATGGCCACAGTGGTGAAGATAGCTACTACAATTGCGATCAGTGTAGTAAATCGTACAAGTACATTGTCAGCTTGATCAAGCACAAGCACAAAGAGCACCTAGACAAGGAGTCATACAAGCAGTCGGATGACGAAGACGATCGGCCTCTGGCCTCCACATCCGCCTCGGCAAGTGCACCAACTGCGAAACCTTCTAGGATCAACCGAAGAGTCGACGGGTTCGACTTTCATCGCAGCGAGCCAAACGGAGCCAAGGAAATCAAGTGCATGATATGCTTGCGACGGTTTACTAAACTACGGGAGCTTAGGAATCATCTACAGAACCATCCCACTGATTTCGATTTTGAGGCGCATGGCGAGCCTATCGAGCGCATTGCGGAAGGATTTTTCAAAACAGCCGTTGAGTCCACGGCAGAGGGCTTAAAGCGGCGAATATTTAGAGATCTCAGAATGGGCGTCTATGGACGCTACTATTCCATCACAAATCAAGCGCGTTATGAAATGACCCTAGATAGCTCGGATACGGACAGTGATGGCGATGGCGACGACAATGTCGTCATCCGACGAAGTTACTCCTGTGAATTGTGCGACTCTCCGGAGGCTAGGTGGCCGCGCAAGTACCTGCTACACCAGCACCATCAGAAGGAGCACACATGGCTAGACGCCCCTCATGTCTGCCAGCGCTGCGACTCGCGGTTTCTCAATCTCCAGCTTCTGAAGCACCATACCAGCCAGCTGTGTCAAAACACTTTGAAGCGCTTTATGTGCGACAAGTGCCCTCAGCGATTCTTTTGGCGTCGCAATTTGCGCGCACACCTTGTCGAGCACAAGTGCAAGCAAGAATCTTATCCATGTGACCAATGCTCTCGTAGCTTTCAAGACAAGAGCGCCGTGACCAAACATAAGCTCATGATGCATCGGGATAGTAACATGGAGCTCCTTCCCCCTGCCGCTGGTGCACCCGTACGTTCTACCGTCCTGCCCTGCTGTACAAGCATTTACAGAGACACGGATTCACTGGGTCCCAAGAGCGTCCAGTGCAAGATTTGTGACATCCAGTTTGTCAGCGTGGCAGACTTGCGAAGGCACATATCTATGCAGGGCCACAGCGATCAACCCTCGGCGTACATGATTAGCACAGCAACTGGCTTTGAGCTCCTGCTGGACGACACAGACGACAGTGATGAGGAAACATCGGGCAGGACGTACTCTTGCGACCTTTGTGATCTGAATTTCCGACGCCGACGAGAGATCAGCGAGCATCAGTACTCCCTCCACAGCTTTGACAAACTGCCACATAACTGCGAGCACTGCATTTTCAAGACGGTTGATAAGAACATGCTGCATCAGCATCTTCGCACGCAGTGTATGAACACCGAAAAGAAGTTTGCCTGCATGCGCTGCGGCTACAAGTTCATGTGGGAGGAGAACTTGGCCCAGCACCTTTCCACCCAGCATTCCAAGCAACCCGCCGTTCCGGAACAGCAGCCACCGCTGAGGAGAAAGAGGCGCTTCCGCTACCAGTGCCCCCATTGCTGGCGTTCCTTTGTCGTTCAGCCCAGCCTGGATAAACACATTCGGGACATGCATtcactgacccccaacaagcttaacatccatatgcggcgacacacgggcgagaagccattcaagtgcgatctctgcgacatgcgcttcacggtccactacgagttgaaggtgcaccgtcggaagcatactggcgagcgaccctaccaatgcacgttttgcgacaaggacttcgctcgaccagacaaactaagacggcacgtcttcatgcacaacgacaagtcgtaG
- Protein Sequence
- MTRTCRVCGCDDGRYWIETPVEKYAEKTFVQLLVELTRIEVVMAQAEKFPQWLCYACAEKLESTYDFVLQARRTHELWLQKIGDSLNGDDEMEGTAALECLRETPIHLFEIEGVTIKTEELASTQQAPKADPLVRPRIVKRSIVHFSDSDEDLDDVPLRQRKIAASVCGSDTTKENVCELCNKVFRYVTNLYRHKQRDHGILGKNGEDYEEDYYKCDLCDKTYKYVMALVKHKHKEHGSVSCRIIPGERCRQLWPKMPIHTVQHPSLKHPLIKSRTNNDSLVHSIIKAVVLSDEDGHSGEDSYYNCDQCSKSYKYIVSLIKHKHKEHLDKESYKQSDDEDDRPLASTSASASAPTAKPSRINRRVDGFDFHRSEPNGAKEIKCMICLRRFTKLRELRNHLQNHPTDFDFEAHGEPIERIAEGFFKTAVESTAEGLKRRIFRDLRMGVYGRYYSITNQARYEMTLDSSDTDSDGDGDDNVVIRRSYSCELCDSPEARWPRKYLLHQHHQKEHTWLDAPHVCQRCDSRFLNLQLLKHHTSQLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKCKQESYPCDQCSRSFQDKSAVTKHKLMMHRDSNMELLPPAAGAPVRSTVLPCCTSIYRDTDSLGPKSVQCKICDIQFVSVADLRRHISMQGHSDQPSAYMISTATGFELLLDDTDDSDEETSGRTYSCDLCDLNFRRRREISEHQYSLHSFDKLPHNCEHCIFKTVDKNMLHQHLRTQCMNTEKKFACMRCGYKFMWEENLAQHLSTQHSKQPAVPEQQPPLRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHSLTPNKLNIHMRRHTGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKDFARPDKLRRHVFMHNDKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00548234;
- 90% Identity
- -
- 80% Identity
- -