Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:11184944-11188666[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00029 0.016 15.3 0.9 2 23 177 199 177 199 0.96

2 16 0.0017 0.097 12.9 2.6 1 23 214 237 214 237 0.96

3 16 0.0031 0.18 12.1 3.7 1 23 308 331 308 331 0.96

4 16 0.0035 0.2 11.9 0.7 2 23 386 407 385 407 0.96

5 16 1.1 64 4.0 0.5 1 20 522 541 522 543 0.84

6 16 0.019 1.1 9.6 0.6 1 23 552 574 552 574 0.94

7 16 0.00025 0.015 15.5 0.7 1 23 581 604 581 604 0.96

8 16 0.00018 0.01 16.0 0.4 2 23 613 634 612 634 0.96

9 16 0.00072 0.041 14.1 0.1 2 22 661 681 660 684 0.90

10 16 0.0013 0.076 13.2 1.2 1 23 718 741 718 741 0.96

11 16 0.97 56 4.2 3.3 1 22 748 769 748 769 0.95

12 16 0.0019 0.11 12.8 0.7 1 23 778 801 778 801 0.97

13 16 1.5e-05 0.00088 19.3 0.5 1 23 822 845 822 845 0.97

14 16 0.036 2.1 8.7 0.2 1 23 855 877 855 877 0.94

15 16 6.1e-05 0.0035 17.4 3.7 1 23 883 905 883 905 0.99

16 16 2e-05 0.0012 18.9 1.2 1 23 911 933 911 933 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00029	0.016	15.3	0.9	2	23	177	199	177	199	0.96
2	16	0.0017	0.097	12.9	2.6	1	23	214	237	214	237	0.96
3	16	0.0031	0.18	12.1	3.7	1	23	308	331	308	331	0.96
4	16	0.0035	0.2	11.9	0.7	2	23	386	407	385	407	0.96
5	16	1.1	64	4.0	0.5	1	20	522	541	522	543	0.84
6	16	0.019	1.1	9.6	0.6	1	23	552	574	552	574	0.94
7	16	0.00025	0.015	15.5	0.7	1	23	581	604	581	604	0.96
8	16	0.00018	0.01	16.0	0.4	2	23	613	634	612	634	0.96
9	16	0.00072	0.041	14.1	0.1	2	22	661	681	660	684	0.90
10	16	0.0013	0.076	13.2	1.2	1	23	718	741	718	741	0.96
11	16	0.97	56	4.2	3.3	1	22	748	769	748	769	0.95
12	16	0.0019	0.11	12.8	0.7	1	23	778	801	778	801	0.97
13	16	1.5e-05	0.00088	19.3	0.5	1	23	822	845	822	845	0.97
14	16	0.036	2.1	8.7	0.2	1	23	855	877	855	877	0.94
15	16	6.1e-05	0.0035	17.4	3.7	1	23	883	905	883	905	0.99
16	16	2e-05	0.0012	18.9	1.2	1	23	911	933	911	933	0.97

Sequence Information

Coding Sequence: ATGACGCGGACTTGCAGAATATGTGGCGGCGACGACGGTCGATACTGGATTGAGACGCCCGTGGAGAAGTACGCAGAGAAGACCTTCGGGCAGCTGCTGGTCGAGCTAACGCGCATCGAGGTGGCCATGGCCGAGTCGGAGAAGTTCCCGCAGTGGCTGTGCAGTGGATGCGCCGACAAGCTGGAGAGTGCCTACGACTTTGTGCTGCAGGCGCGCCAAACGCACGAGCTTTGGGTGCAGAAACTGGGGGACTCTGTGGACGGAGACGATGAAATAAAGGGCACCGAGGCCTTGGAGTGCCTCCGCGAGACACCGATCCACCTGTTCGAAATAGAGGGCGTGACCATCAAGACCGAGGAACTGGATGCTACGCATCAAGTGCCCAAGGCTGATCCTCTTGTGCGTACGCGCTTCGTCAAGCGGAGCATCGTGCACTTCAGTGACTCGGATGACGACCAGGACGATGTGCCACTGCGCCAGCGCAAGATTACCTCCTCGCTCTGCTCCTCTGAGCCGGCGAAGCAGAATGTGTGCGAGCTGTGCAACAAGGCCTTCAGATATGTCACCAATCTGTATCGCCACAAGCAGAGGGATCATGGCGTTCTTGGAAAGAACGGGGAAGACTATGAAGACGACTACTACAAGTGCGACCAGTGCGACAAGACCTACAAGTACGTGATGGCGCTGGTAAAGCACAAGCACAGCGAACATGGAGCCAGTCTCCTGCCCTCCAAGACGTCCAGGCGAAAGTTACCCGGAAGGCCATCGACATTGCCCGAGGATGCCAGTCCATCTAGTCCAGCCTCCACCTCTGGAACCTCCACACATCGCAGCAGAACCAACACCGACACCCTTGTGCACAGCATCATCAAGGCAGTGGAACTGTCTGATGAGGATGGCAACAGCAGCGGGGACAACTACTACAAGTGCGATCAATGCAGCAAATCCTACAAGTACATTGTCAGTTTAATCAAGCACAAGCACAAGGAGCACTCTGACAAACAGTCCGACAAGCAGTCGGATTCCGAGGACGATCAGCCACTGGCCTCCACATCGGCCTCGGCAGTTGCATCACCCCCTAAGCCTTCGAGGATCAACCGAAGAGTCGATGGCTTTGACTACCACCGCTGCGAGCCGAATGGCGCCAAGGAAATCAAATGCATGATCTGCTTACGCCGGTTTACCAAACTGCGGGAGCTGAGGGATCACCTGCAGGCCCATCCCACTGATTTCGGCTTCGAGGCGCATGGCGAGCCTATTGAGCGGATTGCGGAAGGATTTTTCAAGACTGCCGTGGAGTCCACTGCGGAGGGTTTGAAGCGGCGGATCTTTCGGGATCTTAGGATGGGTGTCTATGGGCGCTACTACTCCATCACAAATCAAGCGCGCTACGAGATGACCCTGGACAGCTCAGATACCGACAGTGACGGCGATGGCGAGTCGGATGTTGTCATTCGACGAAGCTATTCCTGCGAGCTGTGCGACTCTCCGGAGGCTAGGTGGCCGCGCAAGTACCTGTTGCACCAGCACCACCGCAACGAGCACACCTGGCTGGACGCGCCGTATGTCTGCCAGCGCTGCGACTCGCGGTTTCTCAGTGCTCAACTGCTGGAGCACCACACCAGCCAGCTGTGCCAAAACACTCTGAAGCGCTTTATGTGCGACAAGTGCCCCCAGCGATTCTTTTGGCGCCGGAATCTCCGCGCCCATCTCGTCGAGCACAAGAGCAAGCAAGAGACCTACCCATGCGACCAATGCTCCCGGAGCTTCCAGGACAAGAGTGCAGTTACGAAACACAAACTGATGATGCATCGGGATAGCAGCATGCAGCTCATCCCCTGCCGCTGGTGCACTCGCACTTTCTACCGACCTGCCCTGTTGTACAAGCACTTGCAAAGGCACGGCTTCACTGGTCAGGATCTTCCTTTGGCTGAAACCCTGCTGGCGGATGCGTCAAAACCGGCTGGACCGAAGAGCATCCAGTGCAAAATGTGTGACATCCAGTTCATCAGCGTGGCTGACTTGCGCAGGCACATATCGATGCAGGGCCACAGCGATCAGCCATCGGCCTACATGATTAGCACTGCAACAGGTTTTGAGCTCCTGCTGGAGGATACGGATGAAAGTGATGAGGAAAGCACGGGCAGATCGTACACCTGCGACCTTTGTGATCTGAACTTCAGGCGACGACGGGAAATGAGCGAGCACCAGTATTCGCTTCACAGCTTCGACAAACTACCACATTCCTGCGAGCATTGCATTTTTAAGACTGTGGATAAGCACATGCTAAATCAACACCTTCGCACTCAGTGTATGAACACGGAGAAGAAGTTCGTCTGCTCGCGGTGTGGCTACAAGTTCATGTGGAAGGAGAATCTGACCCAGCACCTAGCCACCCAGCATCCCAAGCAACCCACCGTTCCAGAGCAGCAGCCTTCGCTGAGAAGGAAGCGTCGGTTCCGCTACCAGTGTCCCCATTGCTGGCGCTCCTTTGTCGTGCAGCCTAGCCTGGATAAGCACATCCGGGACATGCATGTGGCCAAAAAGAATCCAGGAAAGAAGTATCTCTGCTCGCTGTGCGGCCTGGAGTCGCTGACGCCCAATAAACTGAACATTCATATGCGGCGCCACATGGGCGAGAAGCCCTTCAAGTGCGATCTCTGTGACATGCGCTTTACGGTCCACTACGAACTGAAGGTTCACCGCCGGAAACACACCGGTGAAAGACCCTACCAGTGCACCTTTTGCTCCAAGGACTTTGCACGACCGGACAAATTAAGGAGGCACGTCTTTATTCATAATGTCAAATCATAG
Protein Sequence: MTRTCRICGGDDGRYWIETPVEKYAEKTFGQLLVELTRIEVAMAESEKFPQWLCSGCADKLESAYDFVLQARQTHELWVQKLGDSVDGDDEIKGTEALECLRETPIHLFEIEGVTIKTEELDATHQVPKADPLVRTRFVKRSIVHFSDSDDDQDDVPLRQRKITSSLCSSEPAKQNVCELCNKAFRYVTNLYRHKQRDHGVLGKNGEDYEDDYYKCDQCDKTYKYVMALVKHKHSEHGASLLPSKTSRRKLPGRPSTLPEDASPSSPASTSGTSTHRSRTNTDTLVHSIIKAVELSDEDGNSSGDNYYKCDQCSKSYKYIVSLIKHKHKEHSDKQSDKQSDSEDDQPLASTSASAVASPPKPSRINRRVDGFDYHRCEPNGAKEIKCMICLRRFTKLRELRDHLQAHPTDFGFEAHGEPIERIAEGFFKTAVESTAEGLKRRIFRDLRMGVYGRYYSITNQARYEMTLDSSDTDSDGDGESDVVIRRSYSCELCDSPEARWPRKYLLHQHHRNEHTWLDAPYVCQRCDSRFLSAQLLEHHTSQLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKSKQETYPCDQCSRSFQDKSAVTKHKLMMHRDSSMQLIPCRWCTRTFYRPALLYKHLQRHGFTGQDLPLAETLLADASKPAGPKSIQCKMCDIQFISVADLRRHISMQGHSDQPSAYMISTATGFELLLEDTDESDEESTGRSYTCDLCDLNFRRRREMSEHQYSLHSFDKLPHSCEHCIFKTVDKHMLNQHLRTQCMNTEKKFVCSRCGYKFMWKENLTQHLATQHPKQPTVPEQQPSLRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCSKDFARPDKLRRHVFIHNVKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548234;
90% Identity: iTF_00536949;
80% Identity: -