Dpav004811.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila parvula
Gene Symbol
-
Assembly
GCA_018904695.1
Location
JAEIIG010013546.1:73691-77140[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00021 0.016 15.6 0.7 3 23 182 203 181 203 0.96
2 16 0.00085 0.064 13.8 2.8 1 23 220 243 220 243 0.97
3 16 0.0027 0.2 12.2 3.6 1 23 314 337 314 337 0.96
4 16 0.0012 0.087 13.3 0.8 2 23 394 415 393 415 0.96
5 16 4.9 3.7e+02 1.9 0.6 1 20 531 549 531 551 0.80
6 16 0.0015 0.11 13.0 0.6 1 23 561 583 561 583 0.95
7 16 0.00021 0.016 15.7 0.5 1 23 590 613 590 613 0.96
8 16 0.0004 0.031 14.8 1.4 2 23 622 643 621 643 0.96
9 16 0.0014 0.11 13.0 0.0 2 21 670 689 669 694 0.92
10 16 0.00051 0.038 14.5 1.1 1 23 730 753 730 753 0.96
11 16 1.6 1.2e+02 3.4 0.9 1 20 760 779 760 781 0.92
12 16 0.013 0.94 10.1 0.1 1 23 790 813 790 813 0.96
13 16 2.6e-06 0.00019 21.7 0.5 1 23 834 857 834 857 0.97
14 16 0.035 2.6 8.7 0.2 1 23 867 889 867 889 0.94
15 16 0.00017 0.013 16.0 2.1 1 23 895 917 895 917 0.99
16 16 5.8e-05 0.0043 17.4 1.0 1 23 923 945 923 945 0.97

Sequence Information

Coding Sequence
ATGACGCGGACCTGCAGAATCTGCGGCTGCGCTGACGGACGCTACTGGATTGAGACACCCGTAGAAAAGTACGCGGAGAAGACCTTCGGACAGCTGCTGGTCGAGCTAACGAAGATCGAGGTGGCTATGGCCCAGGCTGAGAAGTTCCCCCAATGGCTGTGCTCAGCTTGCGCCCAGAAGTTGGAGACCACCTACGACTTTGTGCTGCAAGCACGCCAAACACACGAGCTTTGGCTGAGGAAGCTGGATGACGACGAACCCGGAGAAGAAATGCTGGGCCCTGAGGCCTTGGACGCCCTCAGGGAGACGCCCATTCAATTATTTGAAATCGAGGGCGTGACCATTAAGACCGAGGAGCTGGAACCGCCCGCGAAGATGGGCAAAGGCATGGCCGCCGATCCTCTGGTACGCTCGCGCTTCGTCAAGCGCACTATTGTACACTTCAGCGACTCGGACGGGGGCGACCAGGACGATGTACCGCTGCGTCAGCGCAAGGGGTCGCCAGTGTCGCAGCCGGCCAGCGCCGAGGAGAAGCACAACATCTGCGAGGTGTGCAACAAGGCGTTTCGATACGTGACTAACCTGTACCGCCACAAGCAAAAGGATCATGGACTGCCCCCCAAGCCTGGCGAGGAGTTCGACGACGATGACAACTACTACAAGTGCGACCAGTGCGACAAGACCTACAAATATGTGATGGCGCTGGTGAAGCACAAGCACACCGAGCACGGCGCCAGTCTATTGCCCTCTAAGACTTCGCGACGGAAGTTACCCGGCAGGCCCTCCGTAATGCCCGGCGATGTGAGTCCCTCCAGTCCAGCTTCTACCTCTGGAACCGCCACGCAGCGCAGTCGCGGTAATACTGACACCCTGGTGCACAGCATCATCAAGGCAGTCGAACTCTCGGACGAGGATGGGAACTGCAGCGAGGACAACTACTACAAGTGCGACCAGTGCAGCAAATCCTACAAGTACATTGTCAGCCTGATCAAGCACAAGCACCGTGAGCACACGGATCAGGACCAGAAGCAGTCCGATTCGGATGATGATCTTCCGCTAGCTTCCACATCGACAGCTTCCACAGCGGCAGCTGCAGCCTCCGCCAAGCCCTCGAGGATCAATCGACGCGTTGAGGACTTTGACCCACATTCCTGTGAGCCGAATGGGGCCAAGGAGATCAAGTGTATGATCTGCCTACGCCGATTCACTAGACTTCGCGAGCTGAGGGATCACCTACAAGACCATCCAATGGATTTCAATTTTGAGGCCCATGGCGAGCCCATTGAGCGCATAGCCGAGGGCTTCTTCAAGACTGCCGTCGAGTCCACGACAGAGGGCCTGAAGCGTCGCATATTCAGAGATCTCAGGTTGGGTGTATATGGCCGGTACTATTCCATAACGAACCAGGCGCGCTACGAGATGAATATGGACAGTTCGGACACGGACAGCGAGGGCGAAGGCGATCAGGCGGATGTGGTGCTGCGTCGTAGCTATGCCTGTGAGCTGTGCGACTCCCTGGAGGCCCGGTGGCCGCGGAAGTACCTGCTGCATCAGCACCATCGCGAGGAGCACACCTGGCTGGAGGCGCCGTTCGTGTGCCAGCGCTGCGACTCCCGCTTCCTCAGCGGCCAGCTGTTGGAGCATCACACCAGCCAGCTGTGCCAGAACACGCTGAAGCGCTTCCAGTGCGACAAGTGTCCGCAGCGCTTCTTCTGGCGGAGCAACCTGCGCGCGCACCTCGTCGAGCACAAAAGTAAGCAAGAGAACTACCCCTGCGACCAGTGCTCTCGGAGTTTCCAGGACAAGAGCGCCGTGACCAAGCACAAGCTGATGGTGCACCGGGACGGCAACATGCAGCTTTTACCCTGCCGCTGGTGCACACGCACCTTCTACCGCCCAGGTCTGCTGCACAAGCACGTGCAGCGGCACGGCTTCAGTGGCCAGGATCTGCCGCTGGCCGAGACTCTGCTGGCGGACGCCTCCAAGCATTCGGGGCAAAAGAGCATCCAGTGCAAGATATGCGACATTCAGTTCATCAGCGTGCCGGATCTGCGGCGTCACATCTCGATGCAGGGTGGGCACAGCGATCAGCCATCGGCTTACATGATCAGCACTGAGACTGGCTTTGAGCTGCTGCTTGAGGATACGGACGACAGTGATGAGGAGAGCCTGCCCTCCACTAGACCCTACAGCTGCGATCTCTGCGATTTAAGCTTCCGGCGGCGACGAGAGATGAGCGAGCATCAGTACTCCCTGCATAGCTTTGACAAGCTGCCACATTCCTGCGAACACTGCATCTTCAAGACTGTGGATAAGTATATGCTTGAGCAGCACTTGGCCAGGCAGTGCCGGAACAGCGAGAAGAAATTCGTCTGCCCGCGCTGCGGCTATAAGTTCATGTGGGAGGAGAATCTCGCCCTGCATTTGGCCACCCAGCATCCCAAACAACCAGCTGTGCTGGAGCATCAGCAGCCGTCGAGAAGGAAGCGACGCTTCCGTTATCAGTGTCCTCATTGCTGGCGATCCTTTGTCGTTCAGCCCAGCTTGGAGAAGCATATCCGGGACATGCACGTGGCCAAGAAGAATCCGGGCAAAAAGTATCTCTGCTCGCTCTGCGGCCTGGAATCACTGACGCCCAACAAGCTGAACATCCATATGCGGCGCCACATGGGCGAGAAGCCGTTTAAGTGCGATCTCTGTGAAATGCGCTTTACGGTATTCTACGAACTGAAGGTGCACCGTCGGAAGCATACGGGCGAGCGACCCTATCAGTGCACCTTCTGTGCCAAGGATTTTGCACGGCCGGACAAGCTCCGGCGACACGTCTTCATGCATAACGTCAAGTCATAG
Protein Sequence
MTRTCRICGCADGRYWIETPVEKYAEKTFGQLLVELTKIEVAMAQAEKFPQWLCSACAQKLETTYDFVLQARQTHELWLRKLDDDEPGEEMLGPEALDALRETPIQLFEIEGVTIKTEELEPPAKMGKGMAADPLVRSRFVKRTIVHFSDSDGGDQDDVPLRQRKGSPVSQPASAEEKHNICEVCNKAFRYVTNLYRHKQKDHGLPPKPGEEFDDDDNYYKCDQCDKTYKYVMALVKHKHTEHGASLLPSKTSRRKLPGRPSVMPGDVSPSSPASTSGTATQRSRGNTDTLVHSIIKAVELSDEDGNCSEDNYYKCDQCSKSYKYIVSLIKHKHREHTDQDQKQSDSDDDLPLASTSTASTAAAAASAKPSRINRRVEDFDPHSCEPNGAKEIKCMICLRRFTRLRELRDHLQDHPMDFNFEAHGEPIERIAEGFFKTAVESTTEGLKRRIFRDLRLGVYGRYYSITNQARYEMNMDSSDTDSEGEGDQADVVLRRSYACELCDSLEARWPRKYLLHQHHREEHTWLEAPFVCQRCDSRFLSGQLLEHHTSQLCQNTLKRFQCDKCPQRFFWRSNLRAHLVEHKSKQENYPCDQCSRSFQDKSAVTKHKLMVHRDGNMQLLPCRWCTRTFYRPGLLHKHVQRHGFSGQDLPLAETLLADASKHSGQKSIQCKICDIQFISVPDLRRHISMQGGHSDQPSAYMISTETGFELLLEDTDDSDEESLPSTRPYSCDLCDLSFRRRREMSEHQYSLHSFDKLPHSCEHCIFKTVDKYMLEQHLARQCRNSEKKFVCPRCGYKFMWEENLALHLATQHPKQPAVLEHQQPSRRKRRFRYQCPHCWRSFVVQPSLEKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHMGEKPFKCDLCEMRFTVFYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVFMHNVKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00548234;
90% Identity
iTF_00524559;
80% Identity
-