Basic Information

Insect: Drosophila tsacasi
Gene Symbol: -
Assembly: GCA_018904565.1
Location: JAEIHY010017812.1:12173-15515[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00062 0.062 14.1 1.0 3 23 182 203 181 203 0.97

2 16 0.00065 0.065 14.0 1.2 1 23 220 243 220 243 0.92

3 16 0.0025 0.25 12.2 3.6 1 23 314 337 314 337 0.96

4 16 0.0036 0.36 11.7 1.7 2 23 392 413 391 413 0.95

5 16 0.99 99 4.0 0.5 1 20 528 547 528 549 0.84

6 16 0.0061 0.61 10.9 0.7 1 23 558 580 558 580 0.95

7 16 0.00022 0.022 15.5 0.9 1 23 587 610 587 610 0.96

8 16 0.00015 0.015 16.0 0.4 2 23 619 640 618 640 0.96

9 16 0.0012 0.12 13.2 0.0 2 21 667 686 666 691 0.92

10 16 0.0016 0.16 12.8 1.0 1 23 727 750 727 750 0.96

11 16 0.76 76 4.4 1.6 1 21 757 777 757 778 0.93

12 16 0.012 1.2 10.1 0.1 1 23 787 810 787 810 0.96

13 16 2.4e-06 0.00024 21.7 0.5 1 23 831 854 831 854 0.97

14 16 0.084 8.4 7.4 0.1 1 23 864 886 864 886 0.92

15 16 8e-05 0.008 16.9 2.0 1 23 892 914 892 914 0.99

16 16 3.2e-05 0.0032 18.1 0.9 1 23 920 942 920 942 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00062	0.062	14.1	1.0	3	23	182	203	181	203	0.97
2	16	0.00065	0.065	14.0	1.2	1	23	220	243	220	243	0.92
3	16	0.0025	0.25	12.2	3.6	1	23	314	337	314	337	0.96
4	16	0.0036	0.36	11.7	1.7	2	23	392	413	391	413	0.95
5	16	0.99	99	4.0	0.5	1	20	528	547	528	549	0.84
6	16	0.0061	0.61	10.9	0.7	1	23	558	580	558	580	0.95
7	16	0.00022	0.022	15.5	0.9	1	23	587	610	587	610	0.96
8	16	0.00015	0.015	16.0	0.4	2	23	619	640	618	640	0.96
9	16	0.0012	0.12	13.2	0.0	2	21	667	686	666	691	0.92
10	16	0.0016	0.16	12.8	1.0	1	23	727	750	727	750	0.96
11	16	0.76	76	4.4	1.6	1	21	757	777	757	778	0.93
12	16	0.012	1.2	10.1	0.1	1	23	787	810	787	810	0.96
13	16	2.4e-06	0.00024	21.7	0.5	1	23	831	854	831	854	0.97
14	16	0.084	8.4	7.4	0.1	1	23	864	886	864	886	0.92
15	16	8e-05	0.008	16.9	2.0	1	23	892	914	892	914	0.99
16	16	3.2e-05	0.0032	18.1	0.9	1	23	920	942	920	942	0.97

Sequence Information

Coding Sequence: ATGACGCGGACGTGCAGAATCTGCGGCGGCGCTGACGGGCGGTACTGGATTGAGACGCCCGTGGAGAAGTATGCGGAGAAGACCTTTGGACAATTGCTTGTCGAGCTAGCGAGAATAGAGGTGGCTATGGCCCAGGCGGAGAAATTTCCCCAGTGGCTGTGCTCCGCCTGCGCCAAGAAGCTGGAGACAACCTACGACTTTGTGCTGCAGGCGCGTCAAACGCACGAGCTGTGGCTGCGCAAGCTGGACGTCGACTCTGAGGACGAAATGCTAGGTCCAGAGGCCTTGGAGGCTCTCAAGGAGACACCCATTCATTTGTTCGAAATCGAGGGCGTGACCATCAAGTCCGAGGTGCTGGAGCCGCCAATGAAGCTGGGAAGAGGCGTGGCAGCTGCCGATCCTCTGGTACGCTCGCGATTCGTCAAGCGCTCCATTATGCATTTCAGCGACTCGGACGAGGGCGACCAGGACGATGTCCCGCTGGGGCAGCGCATAGTTTCGCCAGCCCCACAACCCGTTAGCGCCGAGGAAAAGCACAACCTCTGCGAGGTGTGTAACAAGGCGTTTCGCTTCGTCACCAACTTGTATCGCCACAAACAGCGGGATCATGGGCTGCCCCCCAAGCCGGGCGAAGAGATAGACGACGATGACAACTACTACAAGTGCGACCAGTGTGACAAGGCGTTCAAGTACGTAATGGCGTTGGTAAAGCACAAGCACGCAGAGCACGGAGCAAGTCTACTGCCCGCGAAGACGTCCAGGCGGAAGATGCCAGGCAGGCCCTCGGTGATGCCCGGCGATGCGAGTCCGTCTAGTCCGGCTTCCACCTCGGGAACCTCTACGCAGCGCAGTCGCGGCAATACTGACGCCCTTGTGCACAGCATCATCAAGGCAGTCGAACTCTCGGACGAGGACGGCAACGGCAGCGTGGACAACTACTACAAGTGCGATCAGTGCAGCAAGTCATACAAGTACATTGTCAGCCTGATTAAGCACAAGCACCGGGAGCACACAGAGCAGGACAAAAAGCAGTCTGACTCTGAGGACGATCTGCCGCTGGCCTCCACATCTGCAGCCTTGGGCCTGGCAGCCTCAGCAAAGCCATCGAGGATCAATCGACGCGTCGAGGACTTTGACCCGCACAGCTGCGAGCCGAATGGGGCCAAGGAAATCAAGTGCATGATCTGCCTTCGTCGGTTCACCAGGTTGCGCGAGCTGAGGGATCACCTGCACGCCCATCCCACTGACTTCGATTTCGAGGCCCATGGAGAACCCATCGAGCGCATAGCCGAGGGCTTTTTCAAGACTGCCGTCGAGTCCACGACGGAGGGCCTAAAGCGTCGCATTTTCCGGGATCTCAGGCTGGGCGTGTATGGCCGCTACTATTCCATAACGAACCAGGCGCGCTACGAAATGAATATGGACAGCTCGGACACGGACAGCGAGGGGGAGGGCGAGGCGGACGTTGTGCTGCGGCGCAGCTACGCCTGCGAGCTATGCGACTCTCCGGAGGCGAGGTGGCCGCGGAAGTACCTGCTGCACCAACATCACCGGCAGGAGCACACCTGGCTGGACGCCCCCTATGTCTGCCAGCGCTGCGACTCGCGGTTCCTCAGTGCCCAGCTGCTGGAGCATCACACCAGCCAGCTGTGCCAGAACACACTGAAGCGCTTCCAGTGCGACAAGTGTCCGCAGCGCTTCTTCTGGCGGCGCAACCTACGCGCCCATCTTGTCGAGCACAAGAGCAAGCAAGAGTACTATTCGTGCGATCAGTGCTCCCGCAGCTTCCAGGACAAGAGCGCCGTTACCAAGCACAAGTTGATGGTGCACCGGGATGGCAACGCACAGCTCATTCCCTGCCGCTGGTGCACGCGCACCTTCTATCGCCCGGGTCTGCTGTACAAGCACCTTCAGCGGCACGGTTTTACCGGCCAGGATTTGCCGCTGGCTGAGACGTTGCTGGCGGACGCCTCTAAGCATGCGGGTCAAAAGAGTATCCAGTGTAAAGTGTGCGACATTCAATTCATCAGCGTGGCGGATCTGCGTCGCCACATCGCCATGCAAGGCGGCCACAGCGACCAGCCATCGGCGTACATGATCAGCACTGAGACTGGCTTTGAGCTCCTGCTGGAGGATACGGACGACAGTGATGAGGAGAGTTTCTCCGCCAGCAGAACCTACAGTTGCGACCTCTGCGAGCTGAGCTTTCGACGGCGACGGGAGATGAGCGAACACCAGTACTCCCTGCATAGCTTCGACAAGCTGCCACATTCCTGCGAGCACTGCATTTTCAAGACTGTGGATAAGTCCATGCTAAATCAGCACTTGAGCAGACAGTGTAGGAACAATGACAAAAGGTTCGTCTGTCCGCGCTGTGGCTACAAGTTCATGTGGGAAGAGAATCTCGCCCTGCATCTGGCCACCCAGCATCCCAAGCAACCCGCCTTGCCGGAAGGTCAGCCGGCGTCGCGAAGGAAACGACGGTTCCGCTACCAGTGCCCCCACTGCTGGCGTTCGTTTGTCGTTCAGCCCAGCCTGGAGAAGCACATCCGAGACATGCACGTGGCCAAGAAGAACCCGGGTAAGAAGTACCTCTGTTCGCTGTGCGGCCTGGAAGCCCTGACGCCCAACAAACTTAACATCCACATGCGGCGCCACATGGGAGAGAAGCCGTTTAAGTGCGATCTCTGCGAAATGCGCTTCACGGTCTACTACGAGCTAAAGGTGCACCGCCGGAAGCATACGGGCGAGCGGCCCTATCAGTGCACCTTCTGTGCCAAGGAATTTGCGCGGCCGGACAAGCTGCGGCGCCACGTCTTCATGCACAACGCCAAGACATAA
Protein Sequence: MTRTCRICGGADGRYWIETPVEKYAEKTFGQLLVELARIEVAMAQAEKFPQWLCSACAKKLETTYDFVLQARQTHELWLRKLDVDSEDEMLGPEALEALKETPIHLFEIEGVTIKSEVLEPPMKLGRGVAAADPLVRSRFVKRSIMHFSDSDEGDQDDVPLGQRIVSPAPQPVSAEEKHNLCEVCNKAFRFVTNLYRHKQRDHGLPPKPGEEIDDDDNYYKCDQCDKAFKYVMALVKHKHAEHGASLLPAKTSRRKMPGRPSVMPGDASPSSPASTSGTSTQRSRGNTDALVHSIIKAVELSDEDGNGSVDNYYKCDQCSKSYKYIVSLIKHKHREHTEQDKKQSDSEDDLPLASTSAALGLAASAKPSRINRRVEDFDPHSCEPNGAKEIKCMICLRRFTRLRELRDHLHAHPTDFDFEAHGEPIERIAEGFFKTAVESTTEGLKRRIFRDLRLGVYGRYYSITNQARYEMNMDSSDTDSEGEGEADVVLRRSYACELCDSPEARWPRKYLLHQHHRQEHTWLDAPYVCQRCDSRFLSAQLLEHHTSQLCQNTLKRFQCDKCPQRFFWRRNLRAHLVEHKSKQEYYSCDQCSRSFQDKSAVTKHKLMVHRDGNAQLIPCRWCTRTFYRPGLLYKHLQRHGFTGQDLPLAETLLADASKHAGQKSIQCKVCDIQFISVADLRRHIAMQGGHSDQPSAYMISTETGFELLLEDTDDSDEESFSASRTYSCDLCELSFRRRREMSEHQYSLHSFDKLPHSCEHCIFKTVDKSMLNQHLSRQCRNNDKRFVCPRCGYKFMWEENLALHLATQHPKQPALPEGQPASRRKRRFRYQCPHCWRSFVVQPSLEKHIRDMHVAKKNPGKKYLCSLCGLEALTPNKLNIHMRRHMGEKPFKCDLCEMRFTVYYELKVHRRKHTGERPYQCTFCAKEFARPDKLRRHVFMHNAKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548234;
90% Identity: iTF_00524559;
80% Identity: -