Dseg015255.1
Basic Information
- Insect
- Drosophila seguyi
- Gene Symbol
- -
- Assembly
- GCA_008042675.1
- Location
- VNJU01010397.1:6699-10048[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0013 0.094 13.1 2.6 3 23 182 203 180 203 0.94 2 15 0.0019 0.14 12.6 1.7 1 23 220 243 220 243 0.92 3 15 0.0024 0.18 12.3 3.5 1 23 314 337 314 337 0.96 4 15 0.0037 0.27 11.7 1.7 2 23 392 413 391 413 0.95 5 15 2.9 2.1e+02 2.6 0.5 1 20 528 546 528 548 0.75 6 15 0.0064 0.46 10.9 0.7 1 23 558 580 558 580 0.95 7 15 0.00023 0.017 15.5 0.9 1 23 587 610 587 610 0.96 8 15 0.00097 0.071 13.5 0.5 2 23 619 640 618 640 0.96 9 15 0.001 0.075 13.4 0.0 2 21 667 686 666 691 0.92 10 15 0.00085 0.062 13.7 0.9 1 23 727 750 727 750 0.96 11 15 0.0048 0.35 11.3 0.1 1 23 787 810 787 810 0.97 12 15 2.4e-06 0.00018 21.7 0.5 1 23 831 854 831 854 0.97 13 15 0.087 6.3 7.4 0.1 1 23 864 886 864 886 0.92 14 15 8.3e-05 0.006 16.9 2.0 1 23 892 914 892 914 0.99 15 15 3.3e-05 0.0024 18.1 0.9 1 23 920 942 920 942 0.97
Sequence Information
- Coding Sequence
- ATGACGCGGACGTGCAGAATCTGCGGCGGCGATGACGGGCGCTACTGGATTGAGACGCCCGTGGAAAAGTACGCGGAGAAGACCTTTGGACAACTGCTGGTCGAGCTGGCGAGAATAGAGGTGGCTATGGCCCAGGCGGACAAGTTTCCCCAGTGGCTGTGCTCCGCCTGCGCCCAGAAACTGGAGACCACCTACGACTTTGTGCTGCTGGCGCGCCAAACGCACGAGCTGTGGCTGCGCAAGCTGGACGACGACTCTGGCGACGAAAGGCTAGGTCCAGAGGCCTTGGAAGCTCTCAGGGAGACACCCATCCATTTGTTCGAAATCGAGGGCGTGACCATCAAGTCCGAAGTGCTGGAGCCGCCGATGAAGCAGGGAAGAGGCGTGGCAGCCGCCGATCCTCTGGTACGCTCGCGTTTCGTCAAGCGCACCATCATGCACTTCAGCGACTCGGACGAGGATGACCAGGACGATGTCCCGCTGGGGCAGCGCATAGCTTCGCCAGCCCCACAACCCGGCACCGCGGAGGAGAAGCACCACCTCTGCGAGGTGTGCAACAAGGCGTTTCGCTTCGTCACCAATCTGTATCGCCACAAACAGCGGGATCATGGGCTGCCCGCCAAGCCGGGCGAGGAGATAGACGACGATGACAACTACTACAAGTGCGAGCAATGCGACAAAACGTACAAGTACGTAATGGCGCTGGTAAAGCACAAGCACGCAGAGCACGGAGCGAGTCTGTTGCCCGCGAAGACGTCCAGGCGGAAGATGCCCGGCAGGCCCTCGGTGATGCCCGGCGATGCGAGTCCCTCTAGTCCAGCTTCCACCTCGGGAACCTCCACGCAGCGCAGTCGCGGCAATACTGACGCCCTGGTGCACAGCATCATCAAGGCAGTCGAGCTCTCGGACGAGGACGGTAGCTGCAGCGTGGACAACTACTACAAGTGCGATCAGTGCAGCAAGTCCTACAGGTACATTGTCAGCCTGATCAAGCACAAGCACCGGGAGCACTCGGATCAGGACAAGAAGCAATCGGACTCTGAGGACGATCTGCCGCTGGCCTCCACATCTGCAGCCTTGGCCTCGGCATCCTCGGCAAAGCCCTCGAGAATCAATCGACGCGTCGAGGACTTCGACCCGCACAGCTGCGAGCCGAATGGAGCCAAGGAAATCAAATGCATGATCTGCCTCCGTCGGTTCACCAGGTTGCGCGAGCTGAGGGATCACCTGCACGCCCATCCCACAGACTTTGATTTCGAGGCCCATGGAGAGCCCATCGAGCGCATAGCCGAGGGCTTTTTCAAGACTGCCGTCGAGTCCACGACGGAGGGCCTGAAGCGTCGCATATTCCGGGATCTCAGGCTGGGCGTTTACGGCCGCTACTATTCCATAACGAACCAGGCACGCTACGAAATGAATATGGACAGCTCGGACACGGACAGCGAGGGTGACGGCGAGGCGGACGTTGTGCTGCGGCGCAGCTACGCCTGCGAGCTCTGTGACTCCCCCGAGGCTAGGTGGCCGCGGAAGTACCTGCTACACCAGCATCACCGGCAGCAGCACACGTGGCTTGACGCCCCCTACGTCTGCCAGCGCTGCGACTCGCGCTTCCTCAGTGCCCAGTTGCTGGATCATCACACCAGCCAGCTGTGCCAGAATACACTGAAGCGCTTCCAGTGCGATAAGTGTCCGCAGCGCTTCTTCTGGCGGCGTAACCTACGCGCCCATCTCGTCGAGCACAAGAGCAAGCAAGAGTACTATTCTTGCGATCAGTGCTCCCGCAGCTTCCAGGACAAGAGCGCCGTGACCAAGCACAAGTTGATGGTGCACCGGGATGGCAACGCACAGCTCATTCCATGCCGCTGGTGCACGCGCACCTTCTACCGCCTAGGTCTGCTGTACAAGCACGTGCAGCGGCATGGCTTCACCGGCCAGGATCTGCCGCTGGCCGAAACGCTGCTGGCGGACGCCTCCAAGCATACGGGTCAGAGGAGTATCCAGTGTAAAGTGTGCGACATTCAATTCGTCAGCGTGGCGGATCTGCGTCGACACATCGCCATGCAGGGCGGCCACAGCGACCTGCCATCGGCGTACATGATAAGCACTGAAACTGGCTTTGAGCTCCAGCTGGAGGATACGGACGACAGTGATGAGGAAAGTTTCTCCGCCACCAGAACCTACAGTTGCGGCCTCTGCGACCTGAGCTTCCGACGCCGACGGGAGATGAGCGAGCACCAGTACTCCCTGCATAGCTTTGACAAGCTGCCACATTCCTGCGAGCACTGCATTTTCAAGACTGTTGATAAGaCCCTGCTGGATCAGCACTTGAGCAGACAGTGTAGGAACAATGAGAAGAAGTTCGTCTGTCCGCGGTGTGGCTACAAGTTCATGTGGGAGGAGAATCTGACTCTGCATCTGGCCACACAGCATCCCAAGCAACCCGCCATGCCGGAAAGTCAGGCGCCGCCGCGGAGGAAAAGACGCTTCCGCTACCAGTGCCCCCACTGCTGGCGTTCCTTTGTCGTTCAGCCCAGCCTGGAGAAGCACATCCGGGACATGCACGTGGCCAAGAAGAACCCGGGTAAGAAGTATCTCTGCTCGCTGTGCGGCCTGGAAGCCCTGACGCCCAACAAACTCAACATTCACATGCGGCGTCATATGGGCGAGAAGCCGTTTAAGTGCGATCTCTGCGAGATGCGTTTCACGGTCTACTACGAGCTGAAGGTGCACCGCCGGAAGCATACGGGCGAGCGACCCTATCAGTGCACCTTCTGTGCCAAGGAATTTGCGCGGCCGGACAAGCTGCGGCGTCACGTCTTCATGCACAACGCCAAGGCATAG
- Protein Sequence
- MTRTCRICGGDDGRYWIETPVEKYAEKTFGQLLVELARIEVAMAQADKFPQWLCSACAQKLETTYDFVLLARQTHELWLRKLDDDSGDERLGPEALEALRETPIHLFEIEGVTIKSEVLEPPMKQGRGVAAADPLVRSRFVKRTIMHFSDSDEDDQDDVPLGQRIASPAPQPGTAEEKHHLCEVCNKAFRFVTNLYRHKQRDHGLPAKPGEEIDDDDNYYKCEQCDKTYKYVMALVKHKHAEHGASLLPAKTSRRKMPGRPSVMPGDASPSSPASTSGTSTQRSRGNTDALVHSIIKAVELSDEDGSCSVDNYYKCDQCSKSYRYIVSLIKHKHREHSDQDKKQSDSEDDLPLASTSAALASASSAKPSRINRRVEDFDPHSCEPNGAKEIKCMICLRRFTRLRELRDHLHAHPTDFDFEAHGEPIERIAEGFFKTAVESTTEGLKRRIFRDLRLGVYGRYYSITNQARYEMNMDSSDTDSEGDGEADVVLRRSYACELCDSPEARWPRKYLLHQHHRQQHTWLDAPYVCQRCDSRFLSAQLLDHHTSQLCQNTLKRFQCDKCPQRFFWRRNLRAHLVEHKSKQEYYSCDQCSRSFQDKSAVTKHKLMVHRDGNAQLIPCRWCTRTFYRLGLLYKHVQRHGFTGQDLPLAETLLADASKHTGQRSIQCKVCDIQFVSVADLRRHIAMQGGHSDLPSAYMISTETGFELQLEDTDDSDEESFSATRTYSCGLCDLSFRRRREMSEHQYSLHSFDKLPHSCEHCIFKTVDKTLLDQHLSRQCRNNEKKFVCPRCGYKFMWEENLTLHLATQHPKQPAMPESQAPPRRKRRFRYQCPHCWRSFVVQPSLEKHIRDMHVAKKNPGKKYLCSLCGLEALTPNKLNIHMRRHMGEKPFKCDLCEMRFTVYYELKVHRRKHTGERPYQCTFCAKEFARPDKLRRHVFMHNAKA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00548234;
- 90% Identity
- iTF_00524559;
- 80% Identity
- -