Dlat000924.1
Basic Information
- Insect
- Drosophila lacteicornis
- Gene Symbol
- -
- Assembly
- GCA_008044355.1
- Location
- VNKF01013397.1:109404-112781[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0002 0.016 15.7 0.7 3 23 182 203 181 203 0.96 2 15 0.0058 0.48 11.1 2.8 1 23 220 243 220 243 0.97 3 15 0.0026 0.21 12.2 3.6 1 23 314 337 314 337 0.96 4 15 0.0037 0.3 11.7 1.7 2 23 393 414 392 414 0.95 5 15 1.8 1.5e+02 3.2 0.7 1 19 530 548 530 550 0.76 6 15 0.0063 0.52 10.9 0.7 1 23 560 582 560 582 0.95 7 15 0.0002 0.017 15.7 0.5 1 23 589 612 589 612 0.96 8 15 0.00039 0.032 14.8 1.4 2 23 621 642 620 642 0.96 9 15 0.0035 0.28 11.8 0.0 2 20 669 687 668 693 0.92 10 15 0.0035 0.29 11.7 0.9 1 23 729 752 729 752 0.96 11 15 0.012 0.97 10.1 0.1 1 23 789 812 789 812 0.96 12 15 2.4e-06 0.0002 21.7 0.5 1 23 833 856 833 856 0.97 13 15 0.033 2.7 8.7 0.2 1 23 866 888 866 888 0.94 14 15 0.00019 0.016 15.7 3.6 1 23 894 916 894 916 0.99 15 15 5.5e-05 0.0045 17.4 1.0 1 23 922 944 922 944 0.97
Sequence Information
- Coding Sequence
- ATGACGCGGACGTGCAGAATCTGCGGCGGCGCTGACGGGCGCTACTGGATTGAGACGCCCGTGGAAAAGTACGCGGAGAAGACCTTCGGAcagctgctggtggagctgaCGAGGATTGAGGTGGCTATGGCCCAGGCAGAGAAGTTCCCCCAGTGGCTGTGCTCCGCCTGCACCCAGAAGCTGGAGAGCACCTACGACTTTGTGCTGCAGGCGCGCCAGACGCACGAACTGTGGCTGCGCAAGCTTGAGGACGACTCTGGGGACGAAATGCTGGGGCCCGAGGCCGTGGAGGCTCTCAGGGAGACACCCATCAACCTTTTCGAAATCGAGGGCGTGACCATCAAGaccgaggagctggagccgccGTCAAAGATGGGCAAGAGCGCGGTCGCTGCCGACCCTTTGGTGCGCTCGCGCCTCGTCAAACGCACCATCGTGCATTTCAGCGACTCGGACGGCGGGGACCAGGATGATGTCCCGCTGCGTCAGCGCAGGGTGTCGCCAGCGCCACAGCCCGCCAGCTTGGAGGAGAAGCACAACATCTGCGAGGTGTGCAACAAGGCGTTCCGATACGTGACCAACCTGTATCGCCACAAACAGCGGGATCACGGGCTGCCCCCCAAGCCGGGCGAGGAGATTGACGACGATGACAACTACTACAAGTGCGATCAGTGCGACAAGTCCTACAAGTATGTGATGGTGCTGGTGAAGCACAAGCACACCGAGCACGGAGCGAGTCTCTTGCCCTCGAAGACTTCGAGGCGAAAGTTGCCCGGCAGGCCCTCCGTGATGCGCGGCGATGCGAGTCCCTCTAGTCCAGCTTCTACCTCGGGAACCACCACGCAGCGCAGTCGGGGCAATACTGACACTCTGGTCCACAGCATCATCAAGGCAGTCGAACTCTCGGACGAggatggcagcagcagcgtggaCAACTACTACAAGTGCGATCAGTGCAGCAAGTCCTACAAGTACATTGTCAGCCTGATCAAGCACAAGCACCGGGAGCACACGGCTCAGGACAAGAAGCAGTCGGACTCGGAGGACGATCTGCCGCTGGCCTCCACCTCGGCAGCCTGTGCAGCCCTAGCCGGTCCCGCCAAGCCCTCGAGGATCAATCGACGCGTCGAGGACTTCGACCCGCATTGCTGTGAGCCCAATGGGGCCAAGGAGATCAAGTGCATGATCTGCCTGCGTCGGTTCACCAGGCTGCGTGAGCTGAGGGATCACCTCCACGCGCATCCCACGGACTTTGACTTCGAGGCCCATGGAGAGCCCATCGAGCGCATTGCCGAGGGATTCTTCAAGACTGCCGTCGAGTCCACGACGGAGGGCCTGAAGCGTCGCATATTCCGAGACCTCAGGATGGGCGTCTACGGCCGTTACTATTCCATAACGAACCAGGCGCGCTACGAGATGAATATGGACAGCTCGGACACGGACAGCGAGGGCGACGACGCCGAGGCGGATGTGGTGCTGCGTCGCAGCTACGCCTGCGAGCTCTGCGACTCTGCCGAGGCCAGGTGGCCGCGCAAGTACCTCCTGCACCAGCACCACCGGCAGGAGCACACCTGGCTGGAGGCCCCGTATGTGTGTCAGCGCTGCGACTCCCGCTTCCTCAgcgagcagctgctggagcacCACACCAGCCAGCTGTGCCAGAACACGCTGAAGCGCTTCCAGTGCGACAAGTGTCCGCAGCGCTTCTTCTGGCGCCGCAACCTGCGCGCCCACCTCGTCGAGCACAAAAGCAAGCAAGAGAACTACCCCTGCGACCAGTGCTCGCGCAGCTTCCAGGACAAGAGCGCCGTGACCAAGCACAAGCTGATGGTGCACCGCGACGGCAACATGCAGCTCCTGCCCTGCCGCTGGTGCACGCGCACCTTCTACCGCCCGGCTCTGCTGCACAAGCACGTCCAGCGCCATGGGTTTAGTGGCCAGGATCTGCCGCTGGCCGAGACGCTGCTGGCGGACGCCTCTAAGCATTCGGGCCAGAAGAGCATTCAGTGCAAAATGTGCGACATTCAGTTCATCAGCGTGGCGGATCTGCGTCGTCACGTGGCCATGCAGGAAGGCCACTGCGACCAGCCATCGGCGTACATGATTAGCACGGAAACGGGCTttgagctgcagctggaggatACGGATGACAGCGATGAGGAGGGCTCAACATCCAATAGGACCTACAGATGCGACCTCTGCGAGCTGATcttccggcggcggcgggagaTGAGCGAGCACCAGTACTCCCTGCACAGCTTTGACAAGCTGCCACATTCCTGCGAGCACTGCATCTACAAGACGGTAGATAGGCACATGCTGGACCTGCACTTGAGCAGGCAGTGCCGGAACAACGAGAAGAAGTTCGTCTGCCCGCGCTGCGGCTACAAGTTTATGTGGGAGGAGAATCTCGCCCTTCACCTGGCCACCCAGCATCCCAAGCAACCCACCATGCCGGAGCATCAGCAGCCGTCGCGGAGGAAACGACGCTTCCGCTACCAGTGTCCCCACTGCTGGCGCTCCTTTGTCGTTCAGCCCAGTCTGGAGAAGCATATCCGGGACATGCATGTGGCCAAGAAGAATCCGGGCAAGAAGTATCTGTGCTCGTTGTGCGGCCTGGAATCGCTCACGCCCAACAAGCTGAATATCCACATGCGGCGCCACATGGGCGAGAAGCCCTTTAAGTGCGATCTCTGTGAAATGCGCTTCACTGTCCACTACGAGCTGAAGGTGCACCGGCGGAAGCATACGGGCGAGCGGCCCTATCAGTGCACCTTCTGCGCCAAGGACTTTGCCCGGCCGGACAAGCTGCGGCGCCACGTCTTCATGCACAACGTCAAGTCATAG
- Protein Sequence
- MTRTCRICGGADGRYWIETPVEKYAEKTFGQLLVELTRIEVAMAQAEKFPQWLCSACTQKLESTYDFVLQARQTHELWLRKLEDDSGDEMLGPEAVEALRETPINLFEIEGVTIKTEELEPPSKMGKSAVAADPLVRSRLVKRTIVHFSDSDGGDQDDVPLRQRRVSPAPQPASLEEKHNICEVCNKAFRYVTNLYRHKQRDHGLPPKPGEEIDDDDNYYKCDQCDKSYKYVMVLVKHKHTEHGASLLPSKTSRRKLPGRPSVMRGDASPSSPASTSGTTTQRSRGNTDTLVHSIIKAVELSDEDGSSSVDNYYKCDQCSKSYKYIVSLIKHKHREHTAQDKKQSDSEDDLPLASTSAACAALAGPAKPSRINRRVEDFDPHCCEPNGAKEIKCMICLRRFTRLRELRDHLHAHPTDFDFEAHGEPIERIAEGFFKTAVESTTEGLKRRIFRDLRMGVYGRYYSITNQARYEMNMDSSDTDSEGDDAEADVVLRRSYACELCDSAEARWPRKYLLHQHHRQEHTWLEAPYVCQRCDSRFLSEQLLEHHTSQLCQNTLKRFQCDKCPQRFFWRRNLRAHLVEHKSKQENYPCDQCSRSFQDKSAVTKHKLMVHRDGNMQLLPCRWCTRTFYRPALLHKHVQRHGFSGQDLPLAETLLADASKHSGQKSIQCKMCDIQFISVADLRRHVAMQEGHCDQPSAYMISTETGFELQLEDTDDSDEEGSTSNRTYRCDLCELIFRRRREMSEHQYSLHSFDKLPHSCEHCIYKTVDRHMLDLHLSRQCRNNEKKFVCPRCGYKFMWEENLALHLATQHPKQPTMPEHQQPSRRKRRFRYQCPHCWRSFVVQPSLEKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHMGEKPFKCDLCEMRFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVFMHNVKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00548234;
- 90% Identity
- iTF_00524559;
- 80% Identity
- -