Basic Information

Insect: Drosophila lutescens
Gene Symbol: -
Assembly: GCA_037075285.1
Location: JBAMCF010000681.1:48761-52749[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00031 0.025 15.3 0.9 2 23 179 201 179 201 0.96

2 15 0.0039 0.32 11.8 2.4 1 23 216 239 216 239 0.96

3 15 0.0033 0.27 12.0 3.7 1 23 310 333 310 333 0.96

4 15 0.0038 0.3 11.9 0.7 2 23 389 410 388 410 0.96

5 15 0.02 1.6 9.6 0.6 1 23 555 577 555 577 0.94

6 15 0.00024 0.019 15.7 0.5 1 23 584 607 584 607 0.96

7 15 0.00091 0.073 13.8 1.6 2 23 616 637 615 637 0.96

8 15 0.00077 0.062 14.1 0.1 2 22 664 684 663 687 0.90

9 15 0.0014 0.11 13.2 1.2 1 23 721 744 721 744 0.96

10 15 6.9 5.6e+02 1.6 1.8 1 22 751 772 751 772 0.94

11 15 0.015 1.2 10.0 0.3 1 23 781 804 781 804 0.96

12 15 2.9e-06 0.00023 21.7 0.5 1 23 825 848 825 848 0.97

13 15 0.039 3.1 8.7 0.2 1 23 858 880 858 880 0.94

14 15 6.6e-05 0.0053 17.4 3.7 1 23 886 908 886 908 0.99

15 15 6.4e-05 0.0052 17.5 1.0 1 23 914 936 914 936 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00031	0.025	15.3	0.9	2	23	179	201	179	201	0.96
2	15	0.0039	0.32	11.8	2.4	1	23	216	239	216	239	0.96
3	15	0.0033	0.27	12.0	3.7	1	23	310	333	310	333	0.96
4	15	0.0038	0.3	11.9	0.7	2	23	389	410	388	410	0.96
5	15	0.02	1.6	9.6	0.6	1	23	555	577	555	577	0.94
6	15	0.00024	0.019	15.7	0.5	1	23	584	607	584	607	0.96
7	15	0.00091	0.073	13.8	1.6	2	23	616	637	615	637	0.96
8	15	0.00077	0.062	14.1	0.1	2	22	664	684	663	687	0.90
9	15	0.0014	0.11	13.2	1.2	1	23	721	744	721	744	0.96
10	15	6.9	5.6e+02	1.6	1.8	1	22	751	772	751	772	0.94
11	15	0.015	1.2	10.0	0.3	1	23	781	804	781	804	0.96
12	15	2.9e-06	0.00023	21.7	0.5	1	23	825	848	825	848	0.97
13	15	0.039	3.1	8.7	0.2	1	23	858	880	858	880	0.94
14	15	6.6e-05	0.0053	17.4	3.7	1	23	886	908	886	908	0.99
15	15	6.4e-05	0.0052	17.5	1.0	1	23	914	936	914	936	0.97

Sequence Information

Coding Sequence: ATGACGCGGACTTGCAGAATATGTGGCGGCGACGACGGTCGCTACTGGATTGAGACGCCGGTGGAGAAGTACGCCGAGAAGACCTTCGGCCAGCTGCTGCTCGAACTAACGCGCATCGAGGTGGCCATGGCGCAGGCGGAGAAGTTCCCACAGTGGCTGTGCAACGCGTGTGCCGAGAAGCTGGAGAGCACCTACGACTTTGTGCTGCAGGCGCGCCAGACGCACGAGCTGTGGGTGCAGAAACTCGGAGACTCTGTAGACGGAGACGATCAAATGGATGGCACGGGCACCGAGGCCTTGGAGTGCCTCCGCGAGACACCAATCCACCTGTTCGAAATCGAGGGCGTGACCATCAAATCCGAGGATCTGGCTCCCACGCAGCAAGCGGCCAAGGCAGACCCTTTGGTGCGCACGCGCTTCGTCAAGCGGAGCATCGTGCACTTCAGCGACTCGGATGACGACCAGGACGATGTGCCCCTGCGGCAGCGCAAGTTATCCTCCTCGCTCTGCGCCTCGGAGCCGCCGAAACCGAATGTTTGCGAGCTGTGCAACAAGGCCTTTCGATATGTCACCAATTTGTATCGCCACAAACAAAGGGACCACGGCATCCTGGGCAAAAACGGAGAAGActatGATGATGACTACTACAAGTGCGACCAGTGCGACAGGACCTACAAGTACGTGATGGCACTGGTGAAGCACAAGCACAGCGAGCATGGAGCCAGTCTCCTGCCATCCAAGACATCCAGGCGAAAGTTGCCCGGCAGGCCATCGACTTTGCCCGAGGATGCCAGTCCGTCTAGTCCAGCCTCCACCTCTGGAACCTCCACACATCGCAGCAGGACCAACAACGACACCCTGGTGCACAGCATCATTAAGGCAGTGGAACTATCGGATGAGGATGGCCACAGCAGCGCAGACAACTACTACAAGTGTGATCAGTGCAGCAAATCTTACAAGTACATAGTCAGCTTGATCAAGCACAAGCATAAGGAGCACTCTGACAAGCAGTCTGATAAGCAGTCGGAGACCGAGGACGACCAGCCACTGGCCTCCACGTCGGCCTCGGCAGTTACACCGGCAGCCGCCAAGCCATCGAGAATCAACCGAAGAGTCGACGGCTTCGACTACCATCGCTGCGAGCCAAATGGCGCCAAGGAAATCAAATGTATGATCTGCTTGCGCCGGTTTACCAAACTGCGTGAGCTGAGGGATCACCTGCAGGCCCATCCCACTGACTTCGGCTTCGAGGCGCACGGCGAGCCCATTGAGCGCATTGCGGAGGGATTTTTCAAGACGGCCGTGGAGTCCACGACGGAGGGCTTGAAGCGGCGGATCTTTCGGGATCTCAGGATGGGCGTGTACGGGCGCTACTACTCCATCACTAATCAAGCTCGTTACGAGATGACACTGGACAGCTCGGATACGGACAGTGATGGTGATGTCGAGTCGGATGTCGTCATAAGGAGAAGCTATTCCTGCGAGCTGTGCGACTCTCCGGAGGCTAGGTGGCCGCGCAAGTACCTGCTGCACCAGCACCACCGAAACGAGCACACCTGGCTAGATGCGCCGCATGTCTGTCAGCGCTGCGACTCGCGGTTTCTCAGTGCCCAGCTCCTGGACCACCACACTAGCCAGCTCTGTCAGAACACACTGAAGCGCTTCATGTGCGACAAGTGTCCCCAGCGATTCTTTTGGCGCCGCAATCTCCGCGCCCATCTCGTCGAACACAAGAGCAAGCAAGAGACCTACCCTTGCGACCAATGCTCCCGCAGCTTCCAGGACAAAAGCGCCGTGACCAAGCACAAGTTGATGATCCACCGTGATAGTAATATGCAGCTCCTTCCTTGCCGCTGGTGCACTCGCACCTTCTACCGCCCCGCCCTGCTGTACAAACACTTGCACAGGCACGGGTTTACTGGTCAGGATCTGCCTCTGGCCGAAACTCTGCTGGCGGATGCCTCAAAACGGGCCGGACCGAAGAGCATCCAGTGCAAAATGTGTGACATACAGTTCATCAGCGTGGCGGACTTGCGAAGACACATATCGATGCAGGGCCACAGCGATCAGCCATCAGCCTACATGATTAGTACTGCAACAGGTTttgagctgctgctggaggaTACGGATGACAGTGATGAGGAAAGCACGGGGAGGTCATACACTTGCGATCTTTGTGATCTTAACTTCCGGCGGCGACGGGAAATGAGTGAGCACCAGTACTCGCTCCACAGCTTCGACAAACTACCGCATTCCTGCGAGCACTGCATTTTCAAGACAGTGGATAAGTTCATGCTGGATCAGCACCTTCGCACCCAGTGTATGAACACCGAAAAGAAGTTCGCTTGCTCGCGTTGTGGCTACAAGTTCATGTGGGAGGAGAACCTGACCCAGCATCTAGCCACCCAGCATCCCAAGCAACCCGCCGTTCCGGAGCAGCAGCCACCAATAAGAAGGAAGCGGCGCTTCCGCTACCAGTGTCCCCACTGCTGGCGCTCGTTTGTCGTGCAGCCCAGCCTGGAGAAGCATATTCGGGACATGCATGTGGCCAAGAAGAATCCCGGAAAGAAGTACCTCTGCTCGCTGTGCGGCCTGGAGTCGCTGACACCCAACAAACTTAACATCCATATGCGGCGCCACATGGGCGAGAAGCCCTTCAAGTGCGATCTCTGCGACATGCGCTTTACGGTCCACTACGAACTCAAGGTTCACCGCCGGAAACACACCGGCGAGAGACCCTACCAATGCACCTTCTGCGCCAAGGACTTTGCACGACCAGACAAATTGCGGCGGCACGTCTTTATGCACAACGTCAAGTCATAG
Protein Sequence: MTRTCRICGGDDGRYWIETPVEKYAEKTFGQLLLELTRIEVAMAQAEKFPQWLCNACAEKLESTYDFVLQARQTHELWVQKLGDSVDGDDQMDGTGTEALECLRETPIHLFEIEGVTIKSEDLAPTQQAAKADPLVRTRFVKRSIVHFSDSDDDQDDVPLRQRKLSSSLCASEPPKPNVCELCNKAFRYVTNLYRHKQRDHGILGKNGEDYDDDYYKCDQCDRTYKYVMALVKHKHSEHGASLLPSKTSRRKLPGRPSTLPEDASPSSPASTSGTSTHRSRTNNDTLVHSIIKAVELSDEDGHSSADNYYKCDQCSKSYKYIVSLIKHKHKEHSDKQSDKQSETEDDQPLASTSASAVTPAAAKPSRINRRVDGFDYHRCEPNGAKEIKCMICLRRFTKLRELRDHLQAHPTDFGFEAHGEPIERIAEGFFKTAVESTTEGLKRRIFRDLRMGVYGRYYSITNQARYEMTLDSSDTDSDGDVESDVVIRRSYSCELCDSPEARWPRKYLLHQHHRNEHTWLDAPHVCQRCDSRFLSAQLLDHHTSQLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKSKQETYPCDQCSRSFQDKSAVTKHKLMIHRDSNMQLLPCRWCTRTFYRPALLYKHLHRHGFTGQDLPLAETLLADASKRAGPKSIQCKMCDIQFISVADLRRHISMQGHSDQPSAYMISTATGFELLLEDTDDSDEESTGRSYTCDLCDLNFRRRREMSEHQYSLHSFDKLPHSCEHCIFKTVDKFMLDQHLRTQCMNTEKKFACSRCGYKFMWEENLTQHLATQHPKQPAVPEQQPPIRRKRRFRYQCPHCWRSFVVQPSLEKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVFMHNVKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548234;
90% Identity: iTF_00581711; iTF_00602771; iTF_00486731; iTF_00548234; iTF_00605755; iTF_00565534; iTF_00578718; iTF_00505567; iTF_00507763;
80% Identity: -