Dser003413.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila serrata
Gene Symbol
-
Assembly
GCA_002093755.1
Location
NW:2027526-2031043[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00022 0.014 15.5 2.3 1 23 179 202 179 202 0.95
2 16 0.0027 0.17 12.1 1.1 1 23 219 242 219 242 0.92
3 16 0.0025 0.16 12.2 3.6 1 23 313 336 313 336 0.96
4 16 0.014 0.92 9.8 1.8 2 23 391 412 390 412 0.95
5 16 4.3 2.8e+02 2.0 3.0 1 20 527 546 527 551 0.84
6 16 0.0061 0.4 11.0 0.7 1 23 557 579 557 579 0.95
7 16 0.00022 0.014 15.5 0.9 1 23 586 609 586 609 0.96
8 16 0.00029 0.019 15.1 0.3 2 23 618 639 617 639 0.96
9 16 0.0013 0.082 13.1 0.0 2 21 666 685 665 690 0.92
10 16 0.00046 0.03 14.5 1.1 1 23 726 749 726 749 0.96
11 16 0.2 13 6.2 1.1 1 21 756 776 756 777 0.94
12 16 0.029 1.9 8.8 0.1 1 23 786 809 786 809 0.96
13 16 1.3e-05 0.00087 19.3 0.5 1 23 830 853 830 853 0.97
14 16 0.083 5.4 7.4 0.1 1 23 863 885 863 885 0.92
15 16 8e-05 0.0052 16.9 2.0 1 23 891 913 891 913 0.99
16 16 3.2e-05 0.0021 18.1 0.9 1 23 919 941 919 941 0.97

Sequence Information

Coding Sequence
ATGACGAGGACGTGCAGAATCTGCGGCGGCGATGACGGACGCTACTGGATTGAGACACCCGTTGAGAAATACGCGGAGAAGACCTTCGGACAGCTGCTGGTCGAGCTAACAAGGATCGAGGTGGCAATGGCCCAGGCGGAGAAGTTCCCCCAGTGGCTGTGCTCTGCCTGCGCCCAGAAGCTGGAGAATTGCTATGACTTTGTGCTGCAGGCGCGCCAAACGCACGAGCTGTGGCTGCGCAAGCTGGAAGACGACTCCGCGGACGAACTGCTGGGTCAGGAGGCCTTGGAGGCCCTCAGGGAGACGCCCATTCATTTGTTCGAAATCGAAGGCGTTACCATCAAGTCCGAGGTGCTGGAGCCGCCTCGGAAGATGGGAAGAGGCATGGCCAATGCCGATCCTTTGGTACGGTCGCGGTTCGTCAGGCGCACCATCGTGCACTTTAGCGACTCGGACGGAGGTGATCAGGACGATGTTCCGCTGCTCCAGCGCAAGGATTCGCCAGCGCCACAGACCGTCAGCGTCGAGGAGAAGCACATCTGCGAGGTGTGCAACAAGGCGTTTCGGTACGTCACCAACCTGTATCGCCACAAGCAGCGGGATCATGGGCTGCCCGCCAAGCCCGGCGAAGAGATAGACGATGATGACAACTACTACAAGTGCGAGCAGTGCGACAAGGCCTACAAGTACGTGATGGCGCTGGTGAAACACAAGCACGCAGAGCACGGAGCTAGTCTGTTGCCCGCAAAGACTTCCAGGCGAAAGATGCCTGGCAGGCCCTCTGTTATGCCCGGCGATGCGAGTCCGTCTAGTCCAGCTTCCACCTCGGGAACCTCAACGCACCGCAGTCGCGGCAATACTGACGCCCTGGTGCACAGCATCATTAAGGCAGTTGAACTCTCGGACGAGGACGGCAACTGTAGCGCTGACAACTACTACAAGTGTGATCAGTGCAGCAAGTCCTACAAGTACATTGTCAGCCTGATTAAACACAAGCATCGGGAGCACACGGATCAGGACAAAAAACAGTCAGACTCTGAGGACGATCTGCCGTTGGCCTCCACATCCGCAGTCTTGGCGTCGGCAGCCTCTGCTAAGCCCTCGAGGATCAATCGACGCGTCGAGGACTTCGACCCGCACAGCTGCGAGCCGAATGGGGCCAAAGAAATCAAGTGCATGATCTGCCTACGTCGGTTTACCAAGCTGCGCGAGCTCAGGGATCACCTGCACGCCCATCCCACTGACTTCGATTTCGAGGCCCATGGAGAACCCATCGAGCGTATAGCCGAGGGCTTCTTCAAGACTGCCGTCGAGTCCACGACGGAGGGTCTGAAGCGTCGCATATTTCGGGATCTCAGGCTGGGCGTGTATGGCCGCTACTATTCCATAACGAACCAGGCGCGCTACGAGATGAATATGGACAGCTCGGACACGGACAGTGAGGGTGAGGGTGAGGGGGACGTTGTGCTGCGGCGCAGCTATGCTTGCGAGCTATGTGACTCGCCGGAGGCTAGGTGGCCGCGGAAGTATCTgctgcacctgcaccaccgGCAGGATCACACCTGGCTAGACGCACCCTATGTATGCCAGCGCTGCGACTCGCGCTTTCTCAGTGCCCAGCTGCTGGAGCACCACACCAGTCAGCTGTGCCACAACACGCTGAAGCGCTTCCAGTGCGACAAGTGTCCGCAGCGCTTCTTCTGGCGGCGGAACCTGCGCGCCCATCTCGTCGAGCACAAGAGCAAGCAAGAGTACTATTCGTGCGATCAGTGCTCCCGCAGCTTCCAGGACAAGAGCGCCGTTACCAAACACAAGCTGATGGTCCACCGGGATGGCAACGCACAGCTCATTCCCTGCCGCTGGTGCACGCGCACCTTCTACCGCCCTGGTCTGCTGTACAAACACGTACAGCGGCACGGTTTCACCGGCCAGGATCTCCCGCTGGCCGAGACTCTGCTGGCGGACGCCTCCAAGCATGCGGGTCAGAAGAGTATCCAGTGTAAAATGTGCGACATTCAGTTCATCAGTGTGGCGGATCTGCGTCGTCACATCGCCATGCAGGGGGGCCATAGCGACCAGCCATCGGCGTACATGATAAGCACTGAAACTGGATTTGAGCTCCTGCTTGACGACACGGATGACAGTGATGAGGAGAGTTTCCCCGCCAGTAGAACCTACAGTTGCGACCTCTGCGACCTAAGCTTCCGACGTCGACGGGAGATGAGCGAGCACCAGTACTCCCTGCATAGCTTCGACAAGCTGCCACATTCCTGCGAGCACTGCATCTTCACGACTGTGGATAAGTCCATGCTGGAACAGCACTTGAACAGACAGTGCAGGAACAACGACAAGAAGTTCGTCTGCTCGCGTTGCGGCTACAAGTTCATGTGGGAGGAGAATCTCGCCCTGCATCTGGCCACCCAGCATTCTAAGCAAACCGCCATGCCAGAAAATCAGACTCCGTCGCGAAGGAAACGACGCTTCCGCTACCAGTGTCCCCACTGCTGGCGTTCCTTCGTCGTTCAGCCAAGCTTGGATAAGCATATTCGCGACATGCACGTGGCTAAGAAGAATCCGGGTAAGAAGTATCTTTGCTCGCTGTGCGGCCTGGAAGCCCTGACGCCCAACAAGCTGAACATTCACATGCGGCGCCACATGGGCGAGAAGCCATTCAAGTGTGATCTCTGCGAGATGCGCTTTACGGTGTACTACGAGCTGAAGGTACACCGCCGGAAACATACGGGCGAGCGGCCCTATCAGTGCACCTTCTGTGCCAAGGAATTTGCGCGGCCTGATAAGCTCCGGCGTCATGTCTTCATGCACAATGCCAAATCATAG
Protein Sequence
MTRTCRICGGDDGRYWIETPVEKYAEKTFGQLLVELTRIEVAMAQAEKFPQWLCSACAQKLENCYDFVLQARQTHELWLRKLEDDSADELLGQEALEALRETPIHLFEIEGVTIKSEVLEPPRKMGRGMANADPLVRSRFVRRTIVHFSDSDGGDQDDVPLLQRKDSPAPQTVSVEEKHICEVCNKAFRYVTNLYRHKQRDHGLPAKPGEEIDDDDNYYKCEQCDKAYKYVMALVKHKHAEHGASLLPAKTSRRKMPGRPSVMPGDASPSSPASTSGTSTHRSRGNTDALVHSIIKAVELSDEDGNCSADNYYKCDQCSKSYKYIVSLIKHKHREHTDQDKKQSDSEDDLPLASTSAVLASAASAKPSRINRRVEDFDPHSCEPNGAKEIKCMICLRRFTKLRELRDHLHAHPTDFDFEAHGEPIERIAEGFFKTAVESTTEGLKRRIFRDLRLGVYGRYYSITNQARYEMNMDSSDTDSEGEGEGDVVLRRSYACELCDSPEARWPRKYLLHLHHRQDHTWLDAPYVCQRCDSRFLSAQLLEHHTSQLCHNTLKRFQCDKCPQRFFWRRNLRAHLVEHKSKQEYYSCDQCSRSFQDKSAVTKHKLMVHRDGNAQLIPCRWCTRTFYRPGLLYKHVQRHGFTGQDLPLAETLLADASKHAGQKSIQCKMCDIQFISVADLRRHIAMQGGHSDQPSAYMISTETGFELLLDDTDDSDEESFPASRTYSCDLCDLSFRRRREMSEHQYSLHSFDKLPHSCEHCIFTTVDKSMLEQHLNRQCRNNDKKFVCSRCGYKFMWEENLALHLATQHSKQTAMPENQTPSRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLEALTPNKLNIHMRRHMGEKPFKCDLCEMRFTVYYELKVHRRKHTGERPYQCTFCAKEFARPDKLRRHVFMHNAKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00548234;
90% Identity
iTF_00524559;
80% Identity
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