Dtak007430.1
Basic Information
- Insect
- Drosophila takahashii
- Gene Symbol
- -
- Assembly
- GCA_018152695.1
- Location
- JAECXN010000004.1:7590858-7595141[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.00028 0.017 15.3 0.9 2 23 172 194 172 194 0.96 2 16 0.0057 0.35 11.2 2.5 1 23 209 232 209 232 0.96 3 16 0.0031 0.19 12.1 3.7 1 23 303 326 303 326 0.96 4 16 0.0035 0.21 11.9 0.7 2 23 383 404 382 404 0.96 5 16 3.4 2.1e+02 2.5 1.1 1 20 519 538 519 540 0.83 6 16 0.018 1.1 9.6 0.6 1 23 549 571 549 571 0.94 7 16 0.00025 0.015 15.5 0.7 1 23 578 601 578 601 0.96 8 16 0.00083 0.051 13.8 1.6 2 23 610 631 609 631 0.96 9 16 0.0007 0.043 14.1 0.1 2 22 658 678 657 681 0.90 10 16 0.0013 0.08 13.2 1.2 1 23 715 738 715 738 0.96 11 16 10 6.1e+02 1.0 0.9 1 22 745 766 745 766 0.93 12 16 0.0064 0.4 11.0 0.4 1 23 775 798 775 798 0.97 13 16 2.6e-06 0.00016 21.7 0.5 1 23 819 842 819 842 0.97 14 16 0.035 2.2 8.7 0.2 1 23 852 874 852 874 0.94 15 16 6e-05 0.0037 17.4 3.7 1 23 880 902 880 902 0.99 16 16 5.9e-05 0.0036 17.5 1.0 1 23 908 930 908 930 0.97
Sequence Information
- Coding Sequence
- ATGACGCGGACTTGCAGAATATGTGGCGGCGACGACGGTCGCTACTGGATTGAAACGCCCGTGGAGAAGTACGCCGAGAAGACCTTTGGCCAGCTGCTGCTCGAACTAACGCGCATCGAGGTGCCCATGGCGCAGGCGGAAAAGTTCCCACAGTGGTTGTGCAACGCGTGTGCCGAGAAGCTGGAGAGCACCTATGATTTCGTGCTGCAGGCGCGCCAGACGCACGAGCTGTGGGTGCAGAAACTGGGGGACGATCAAATGGAAGGCACCGAGGCTTTGGAATGCCTCCGCGAGACACCCATCCACCTGTTCGAAATCGAGGGCGTGACCATCAAATCCGAGGATCTGCCGCCCACGCAGCCAGCGGCCAAGGCCGATCCTTTGGTGCGCACGCGTTTCGTCAAGCGGAGCATCGTGCACTTCAGCGACTCGGACGACGACCAGGACGACGTGCCCCTGCGGCAGCGCAAGATTACCTCCTCGCTGTGCGCCTCGGAGCCGCCGAAGCCGAATGTCTGCGAGCTGTGCAACAAGGCCTTTCGATATGTCACCAATTTGTATCGTCACAAGCAGAGGGACCACGGCATATTGGGAAAAAACGGAGAAGACTATGAAGACGACTACTACAAGTGCGACCAGTGCGAGAAGACCTACAAGTACGTGATGGCACTGGTTAAGCACAAGCACAGCGAGCATGGAGCCAGTCTGCTGCCCTCCAAGACTTCCCGGCGAAAGTTACCCGGCAGGCCGTCGACTTTGCCGGAGGATGGCAGTCCATCCAGTCCAGCCTCCACCTCGGGAACCTCCACGCATCGCAGCAGGACCAACAACGACACCCTGGTGCACAGCATCATCAAGGCAGTGGAACTATCGGATGAGGACGGCCACAGCAGCGCCGACAACTACTACAAGTGCGACCAGTGCAGCAAATCCTACAAGTACATAGTCAGCTTGATCAAGCACAAGCACAAGGAGCACTCGGACAAGCAGTCCGATAGGCAGTCGGAGACCGAGGACGATCAGCCACTGGCCTCCACATCCTCGGCCTCGGCACTTCCACCGGCAGCCGCCAAGCCATCGAGGATCAACCGAAGAGTCGACGGCTTCGACTACCATCGCTGCGAGCCGAATGGCGCCAAGGAAATCAAGTGTATGATCTGCCTGCGCCGGTTCACCAAACTGCGTGAGCTGAGGGATCACCTGCAGGCCCATCCCACGGACTTTGGCTTCGAGGCGCATGGCGAGCCGATTGAACGCATTGCCGAGGGATTCTTCAAGACGGCCGTGGAGTCCACAGCGGAGGGCTTGAAGCGGCGCATCTTTCGGGATCTCAGGATGGGCGTGTACGGGCGCTACTACTCCATCACCAATCAGGCTCGCTACGAGATGACCCTTGACAGCTCGGATACGGACAGCGATGGCGATGTCGAGTCGGATGTCGTCATCAGGCGCAGCTATTCCTGCGAGCTCTGCGATTCTCCGGAGGCCAGGTGGCCGCGCAAGTACCTGCTGCACCAGCACCACCGGAACGAGCACACCTGGCTTGAGGCGCCGCATGTCTGCCAGCGCTGCGATTCGCGGTTTCTCAGTGCCCAGCTTTTGGAACACCACACCAGCCAGCTGTGCCAGAACACCCTGAAGCGCTTCATGTGCGACAAGTGTCCCCAGCGATTCTTTTGGCGCCGCAATCTCCGCGCCCATCTCGTCGAGCACAAGAGCAAGCAAGAGACCTACCCGTGCGACCAATGCTCCCGCAGTTTCCAGGACAAAAGCGCCGTGACCAAGCACAAGTTGATGATGCACCGCGATGGTAATATGCAGCTCCTTCCCTGCCGCTGGTGCACTCGCACCTTCTACCGCCCCGCCCTGCTGTACAAACACTTGCACAGGCACGGCTTCACTGGGCAGGACCTGCCCCTGGCTGAAACTCTGCTGGCGGATGCCTCCAAACCGGCCGGACCGAAGAGCATCCAGTGCAAAATGTGCGACATTCAGTTCATCAGCGTGGCGGACCTGCGAAGGCACATCTCGATGCAGGGCCACAGCGATCAGCCATCGGCCTACATGATTAGCACTGCCACTGGATTTGAGTTGCTGCTGGAGGATACGGATGAGAGTGATGAGGAAAGCACGGGAAGGTCGTACACTTGCGATCTTTGTGATCTGAACTTCCGGCGGCGACGGGAGATGAGTGAGCATCAGTACTCGCTGCACAGCTTCGACAAACTACCTCATTCCTGCGAGCAGTGCATTTTTAAGACAGTGGATAAGTTCATGCTGGATCAGCACCTGCGCACCCAGTGCATGAACACCGAAAAAAAGTTTGTGTGCTCGCGCTGCGGCTACAAATTTATGTGGGAGGAGAATCTGACCCAGCACCTGGCCACCCAGCATCCCAAGCAACCCACCGTTCCGGAGCAGCAGCCGCCGTTGAGGAGAAAGCGACGCTTCCGCTACCAGTGTCCCCACTGCTGGCGCTCGTTTGTCGTGCAGCCCAGTCTGGAGAAACATATTCGGGACATGCATGTGGCCAAGAAGAATCCGGGAAAGAAGTACCTCTGCTCACTGTGCGGCCTGGAGTCTCTGACCCCTAATAAGCTGAACATCCATATGCGGCGACACATGGGCGAGAAGCCCTTCAAGTGCGATCTCTGCGACATGCGCTTTACGGTCCACTACGAACTAAAGGTTCACCGCCGGAAACACACCGGCGAGAGACCCTACCAATGCACCTTTTGCGCTAAGGACTTTGCACGACCCGATAAATTACGGCGGCACGTCTTTATGCACAATGTCAAGTCATAG
- Protein Sequence
- MTRTCRICGGDDGRYWIETPVEKYAEKTFGQLLLELTRIEVPMAQAEKFPQWLCNACAEKLESTYDFVLQARQTHELWVQKLGDDQMEGTEALECLRETPIHLFEIEGVTIKSEDLPPTQPAAKADPLVRTRFVKRSIVHFSDSDDDQDDVPLRQRKITSSLCASEPPKPNVCELCNKAFRYVTNLYRHKQRDHGILGKNGEDYEDDYYKCDQCEKTYKYVMALVKHKHSEHGASLLPSKTSRRKLPGRPSTLPEDGSPSSPASTSGTSTHRSRTNNDTLVHSIIKAVELSDEDGHSSADNYYKCDQCSKSYKYIVSLIKHKHKEHSDKQSDRQSETEDDQPLASTSSASALPPAAAKPSRINRRVDGFDYHRCEPNGAKEIKCMICLRRFTKLRELRDHLQAHPTDFGFEAHGEPIERIAEGFFKTAVESTAEGLKRRIFRDLRMGVYGRYYSITNQARYEMTLDSSDTDSDGDVESDVVIRRSYSCELCDSPEARWPRKYLLHQHHRNEHTWLEAPHVCQRCDSRFLSAQLLEHHTSQLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKSKQETYPCDQCSRSFQDKSAVTKHKLMMHRDGNMQLLPCRWCTRTFYRPALLYKHLHRHGFTGQDLPLAETLLADASKPAGPKSIQCKMCDIQFISVADLRRHISMQGHSDQPSAYMISTATGFELLLEDTDESDEESTGRSYTCDLCDLNFRRRREMSEHQYSLHSFDKLPHSCEQCIFKTVDKFMLDQHLRTQCMNTEKKFVCSRCGYKFMWEENLTQHLATQHPKQPTVPEQQPPLRRKRRFRYQCPHCWRSFVVQPSLEKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVFMHNVKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00548234;
- 90% Identity
- iTF_00536949;
- 80% Identity
- -