Dfal000961.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila falleni
Gene Symbol
L
Assembly
GCA_035045575.1
Location
JAWNOV010000011.1:4662565-4672062[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1e-05 0.00082 19.8 2.9 1 23 187 209 187 209 0.98
2 17 0.38 28 5.6 6.2 1 23 215 237 215 237 0.97
3 17 1.8e-07 1.4e-05 25.4 3.2 1 23 243 265 243 265 0.99
4 17 1.3e-05 0.001 19.6 0.4 1 23 271 293 271 293 0.99
5 17 0.021 1.6 9.5 0.2 2 23 380 404 379 404 0.90
6 17 0.0012 0.09 13.4 0.2 2 23 432 454 431 454 0.95
7 17 0.029 2.2 9.0 0.7 1 23 541 563 541 563 0.97
8 17 0.0082 0.62 10.8 0.1 2 23 571 592 570 592 0.91
9 17 2.5e-05 0.0018 18.7 0.3 1 23 600 625 600 625 0.93
10 17 4.6 3.5e+02 2.1 1.5 2 23 661 683 660 683 0.94
11 17 0.0027 0.2 12.3 1.1 1 23 734 757 734 757 0.97
12 17 0.0017 0.13 12.9 1.8 2 23 926 948 925 948 0.96
13 17 0.12 9.2 7.1 0.1 1 23 954 976 954 976 0.92
14 17 0.27 20 6.0 0.6 2 23 984 1005 983 1005 0.96
15 17 0.79 59 4.5 0.5 2 23 1105 1126 1105 1126 0.94
16 17 0.039 2.9 8.7 0.0 1 23 1136 1158 1136 1158 0.96
17 17 0.00024 0.018 15.6 1.2 1 23 1163 1185 1163 1185 0.97

Sequence Information

Coding Sequence
ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagattCAAGCTACAAAGGAGATTTCAAATAACgATATGTACAGCACACACACCTCCTCCAGCTACTCGCCGAGCATCTCGGACGGCACAATGACGCCCAACTCAcagcatccacatccacatccgcatTCACAGCTCTCAGCTGCTGGAGAGGATCCTAGCTCAGAGCAGACCAAGGCGAATGGAgacacagcaacagctgctgatgaggagcgagagagagagcgagatagagagcgagagagagagagggagccaGTCAAATTAAAGCGACCTGCTCAtttgcatcatcatcatcatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAAGGAGCCACAGGAGgtggaggagcaggaggaggaacaggagcaggaggaggaggaggagggggaggaCATGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAATGCGAATACTGCGCCAAGTTATTCAAGCACAAACGTTCCCGAGATCGTCATAAGAAACTCCACACCAACGAGAGGAACTACAAGTGTCCACATTGCGAGGCCGCTTTCTCCAGAAGcGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGGGGCTACAACACGGCGGCCGCCTTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCAATACTGGCAGCGGGTGGCAACCCCAATGCCCTCAACTACAGTCCACGTAGCACGGGTTCTGCATCCATCTCCAGCAATGGGAGTCTGCACAAGCGACGCTATGCATTGGCACTCGCCTCCGACAGCAGTCCCAGTCGCATGGAGTACCCGAAACGTGGTCGCGGTCAGGTGGCAACCACACCCGTATCGATAACGACAACGACACCGATAACCACACCGATACCGATACCGACGCCATTGCTGCGTTGCACCTACTGTCCCAAGGTGACGGAATTTAGCAGCTTGGAGCAATTGAATGCACATCTCCAACAGGCACATGAGCAGCGGGAGCAGGCGAGAATTACGACGACACCTGGCGGCGGGGATGGGGAGACGCTGCAGTCGAATGGCTTTCAGTTAAGCTGCGAGTACTGCACCATGAGATTCGTGAATATCGCTGGATTGTTCCAACACATGCGTGCCACACATTTGGATCGTTTGAGCAGTCCCAACTCCTACTATGAGCACTTTAATCGTCTGGCCACCGCGGGCACATTTAGTCCACGTCTGGCACTGGAGCTGCCCAAGATTAAGCAGGACTTGAGCAGTCCACAGCAGCGGGAGCAGCACATGGAGAAGCCGGAACAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGCACAGTGTcgccaccaacaccaacaacgacaacagtaATGCCAACACAAGCGCCACCTGGCGTCTTCTTTTGCAACCAATGCAATGCTGGGTTGCCAGACTTTGAAAGCTTTCGCAATCATTTGAAGACACACATAGCCGAAGGCATGCAACTAATCTGTCCACATTGTGGATTAAGTCTGCCCGAGCAGAGTGAATATGAACGTCATGTGGTTGCCCATTTTTTGATCACCAGCTCGGAGTTCAATTGCAGTGCCGGCAGCTGTGGCAAATCCTTTAGCAAGTCAGATGAACTGCAGCAGCATTTGAATAGCGAGCATGTGTTGACGCTGCTCAAGTGCAGCCTCTGCTCGGAGCTGTGCGAATCCAGGATGGCCATGCAGCTCCATTTGGCCTGTGCGCACAGTCAGGAGACGAAGCTGTTGCGCTGCAGCGCCTGCATGGAGATCTTTCGCAATGATACGGACTTTCATGTGCATGTGAAGACGAGGCATCAGGGAGGCACAGGCGGAGGGGGAGTGGCAGGAGGAGCTGGACTCGGAGGAGGTGCTGTAACTGCCAATCCCTTGCAGTGCATGTTCTGTCGCGCTGTTTGCAATTCGGAGCTGGAGATGCACTTTCATCTGGCGGCACATGCGCGTCAGTTCCGTTGTCCCTCCTGTCCCGAAACCTTCCATGTGGAGTTTCTGCTGGACAGGCACATGCAGAGTCAGCATGGCGGCGTCAAGGATTCCCCGGTGAAGGAACCCAGCAGTTCACCCAACATGGGCAGTTTGTATGTGAATGCCTTGTTGCCACCGCTTGCGgcagctgccgccgctgctgcggtggccaccaacaacaacagcaatcttCACATAGACTACAATGTGGCTTTTAAGGGACTCTTTGGCGGAGCAGCGGGTGCTGGTGCAGCTGCTACACCCGGTGGCAAGTTCTACAGTCCATTGCAGGTGGACACGAGTGGACTGAAGCCACAGCAGTCACCACATCCGGCACTTATGTACGGATTGAGTCAACGCTATCTGATGGAAATGTATGCGGCTAAGGCCACGTCTCCGGCGGCTGCAGTCGCTCCGGATGTGCCACAGTCCACAGCGGTCACCGCAGCCAGTGGCAACTACAGCTGTGGCATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAACTCCATTCGCATCGCAAGCTGGCCCACAATCTGAAGACCGGAGTGAGTTTGAGATGCGCCTATTGCTCCGGCAACTTCAAGTCGCGTGCTGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGTGATGAGATCTTTCCCTCGCCGGCCATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAATCCGGCAAGTGTGCCCACTGTGGCCAACAGCTGGAGCACGTGGCCGCCTTTCGGGCTCATCTCAGCGAGCATGGCGGCGATGGTAATCTGCCCATGGCTTGCATCTGTTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGTCTGCATGCCAAGTTCCACACCAAGTCGCCAGGTGGCGCTGCTGGTGGCAGTCTCCAGGAGCCGGTCTGTGCTCTGTGCCTGGAGCCGTTGCCGGGTGCCGGAGAAACAGCCAAGTTGTGTGAGAAATGTTGTCGCAAGCACAATCTCAATGGCAAGCGACACAAGGAACCGACTCCAGTGGCTGCAGCTGCTCCGGTTAATGCGGCCTCCGCATATCTGGAGAATCGCTGCAATCTCTGCAAAATGATCTTACCGCATGCCCAGAAACTGCAGGAGCATCTGGTGGAGCACACGTTTGCCGGCACCGAACAGCGTGGCTTCAATTGCTACATCTGCTCCGCCGTATTTACCGCCCCCGCCGGACTGCTCAGTCACATTGCCGAGCACGGTGCTCGGCCCTATGACTGCAATCTGTGCCCCGAGAAGTTCTACTTTCGTGCCGAACTGGAGCATCATCAGCGTGCCCATGAGCTGAGACCGGCAGCTCCTTCAGCTGGACGCATTCCACCCAAGCAGGAGACTCGCAGCTCCTCGGCCAGTTCCCCCCTTGCCCCGAGTCCCAGCCATGTCAAGCAGGAGCTCTATGAGTCCGAGACGGCACCGTCACCCGCTGCCGAGGAACCCTCCTCCGCCCAGGAGGATGAGGAGTACATTGAGGTGGAGCAGGTGCCGCATGAAACACGTTCCGGAGAACTCCTGAATTCCGCACACACCGAACGTTCCAGCAGCAGCGCCTAA
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTMTPNSQHPHPHPHSQLSAAGEDPSSEQTKANGDTATAADEERERERDREREREREPVKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKGATGGGGAGGGTGAGGGGGGGGHGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRGRGQVATTPVSITTTTPITTPIPIPTPLLRCTYCPKVTEFSSLEQLNAHLQQAHEQREQARITTTPGGGDGETLQSNGFQLSCEYCTMRFVNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLSSPQQREQHMEKPEQELPTDLSSNKRRTVSPPTPTTTTVMPTQAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLITSSEFNCSAGSCGKSFSKSDELQQHLNSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACMEIFRNDTDFHVHVKTRHQGGTGGGGVAGGAGLGGGAVTANPLQCMFCRAVCNSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDSPVKEPSSSPNMGSLYVNALLPPLAAAAAAAAVATNNNSNLHIDYNVAFKGLFGGAAGAGAAATPGGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAAVAPDVPQSTAVTAASGNYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGGAAGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRHKEPTPVAAAAPVNAASAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPAAPSAGRIPPKQETRSSSASSPLAPSPSHVKQELYESETAPSPAAEEPSSAQEDEEYIEVEQVPHETRSGELLNSAHTERSSSSA