Basic Information

Insect: Drosophila parthenogenetica
Gene Symbol: L
Assembly: GCA_035047505.1
Location: JAWNPM010000080.1:14883304-14893327[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00084 19.8 2.9 1 23 172 194 172 194 0.98

2 17 0.38 29 5.5 6.2 1 23 200 222 200 222 0.97

3 17 1.9e-07 1.4e-05 25.4 3.2 1 23 228 250 228 250 0.99

4 17 1.4e-05 0.001 19.5 0.4 1 23 256 278 256 278 0.99

5 17 0.029 2.2 9.1 0.2 2 23 355 379 354 379 0.91

6 17 0.0026 0.2 12.3 0.2 2 23 422 444 421 444 0.95

7 17 0.03 2.2 9.0 0.7 1 23 530 552 530 552 0.97

8 17 0.0056 0.42 11.3 0.1 2 23 560 581 559 581 0.91

9 17 0.00022 0.017 15.7 0.2 1 23 589 614 589 614 0.89

10 17 1.2 89 4.0 1.3 2 23 650 672 649 672 0.95

11 17 0.0028 0.21 12.3 1.1 1 23 724 747 724 747 0.97

12 17 0.0018 0.13 12.9 1.8 2 23 940 962 939 962 0.96

13 17 0.13 9.4 7.1 0.1 1 23 968 990 968 990 0.92

14 17 0.28 21 6.0 0.6 2 23 998 1019 997 1019 0.96

15 17 0.81 61 4.5 0.5 2 23 1120 1141 1120 1141 0.94

16 17 0.034 2.6 8.8 0.0 1 23 1151 1173 1151 1173 0.96

17 17 0.00024 0.018 15.6 1.2 1 23 1178 1200 1178 1200 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00084	19.8	2.9	1	23	172	194	172	194	0.98
2	17	0.38	29	5.5	6.2	1	23	200	222	200	222	0.97
3	17	1.9e-07	1.4e-05	25.4	3.2	1	23	228	250	228	250	0.99
4	17	1.4e-05	0.001	19.5	0.4	1	23	256	278	256	278	0.99
5	17	0.029	2.2	9.1	0.2	2	23	355	379	354	379	0.91
6	17	0.0026	0.2	12.3	0.2	2	23	422	444	421	444	0.95
7	17	0.03	2.2	9.0	0.7	1	23	530	552	530	552	0.97
8	17	0.0056	0.42	11.3	0.1	2	23	560	581	559	581	0.91
9	17	0.00022	0.017	15.7	0.2	1	23	589	614	589	614	0.89
10	17	1.2	89	4.0	1.3	2	23	650	672	649	672	0.95
11	17	0.0028	0.21	12.3	1.1	1	23	724	747	724	747	0.97
12	17	0.0018	0.13	12.9	1.8	2	23	940	962	939	962	0.96
13	17	0.13	9.4	7.1	0.1	1	23	968	990	968	990	0.92
14	17	0.28	21	6.0	0.6	2	23	998	1019	997	1019	0.96
15	17	0.81	61	4.5	0.5	2	23	1120	1141	1120	1141	0.94
16	17	0.034	2.6	8.8	0.0	1	23	1151	1173	1151	1173	0.96
17	17	0.00024	0.018	15.6	1.2	1	23	1178	1200	1178	1200	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGCTTTATCGCGGTCCCAGCTCGCGTTTAGAGAATTTAATTGAGAAAATTCAAGCCACAAAGGAGATTTCCAATAACGACATGTACAGCACACACACCTCCTCGAGCTATTCGCCTAGCATCTCGGATGGAACCCTGACGCCCAACTCGCACCAGCCGCATCCACATTCGCATCCACAGCTCTCAGGTGCTGGGGAGGATCTGGGCAAGGCAAATGGGGATAAGGTAGCTCCTATCGATGAGGaacaagagagagaaagggagagggagCGGGAACGGGAGCCACCCAAATTAAAGCGCCCCGCCCACctacatcatcattatcatcatcagcaaGCGCTGAAAATTGCGAACAAGCTGCGCAAAATCAATAAGGAAGCCAAACTCGCAGGGACCACAGGGGCAGGAGGAGGCGtaggtggaggaggaggactTGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGTATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGCCTCGGTTACTTGAAGCATCACGTCCAGAGTCACGCCGAGCATTTGCCTTTCAAATGCGAATACTGCGCCAAATTATTCAAGCACAAACGCTCCCGAGATCGCCATAAGAAACTCCACACCAACGAGAGGAACTACAAGTGTCCACATTGCGAGGCCGCTTTCTCCAGAAGTGACCACCTGAAGATCCACATGAAGACCCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATAGGGGCTACAACACGGCTGCGGCCCTGACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCAATACTAGCAGCAGGTGGCAACCCTAACGCGCTCAACTACAGTCCCCGCAGCACTGGCTCCGCCTCCATCTCCAGCAACGGCAGTCTCCACAAACGTCGCCATGCTCTGGCTCTCGCCTCTGACAGCAGCCCCAGTCGCCTTGAGTACCCCAAACGTGGCCGAACACAagttgctgccacgcccactcctACGCCAATGCCTACGCCGCTGCTCCGCTGCAGCTATTGTCCCAAGGCGACGGAGTTTAGCAGCTTGGAACAGCTGAATGCCCACTTGCAGTTGTCCCACGAGCAGCAGGCGAGGATTGCGCCCACTACTACGTCGGGAAGAGCAGCTGGCGGGGCAGGAGGAGGCGGAGTGTTAGGTGGATTAGTAGGAGGAGATGTGGAAGGCCAGTCGAATGGGTTCCAGCTGAGCTGCGAGTACTGCACCATGAAATTCGGCAATATTGCGGCTCTCTTTCAACACATGCGTGCCACACATCTGGATCGTCTGAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGCCTCGCCACCGCAGGCACTTTTAGTCCCCGCCTGGCCATGGAGCTTCCCAAAATTAAGCAGGATCTGGGCAGTCCACATCGGGACCGAGAAAGGGAACGTGAACGTGAACTGGAGCTGGAGAAGCCGGAGCAGGAGTTGCCGACGGATTTGAGCAGCAACAAGCGAAGGGGTacaccaccacaacaacaagggGCGCCACCTGGCGTCTTCTTTTGTAACCAATGCAATGCGGGTTTACCCGACTTCGAGAGCTTCCGGAATCACCTGAAGACGCATATAGCCGAGGGCATGCAGCTAATCTGTCCCCATTGCGGGCTCAGTCTGCCCGAACAAAGCGAGTTCGAAAGGCACGTTGTCGCCCACTTTCTGATATCCGGCAGCGAGTTTAACTGCAGTGCCAACAGCTGTGGAAAATCTTTTGCCCAGTCGGAAGAACTGCAGCAGCATTTGAGTGGGGAGCACGTGGTCACACTGCTCAAATGCACGCTCTGCTCGGAGCTTTGCGAGACTAGGATGGCCATGCAGCTTCATTTGGCATGCGCCCACAGCCAAGAGACGAAGCTGCTCCGATGCAGCGCCTGCCTGGAGATCTTTCGGAGTGACACCGACTTCCATGTGCACGTCAAGACACGTCACCAACTGCCGAGTACCCAAGGAGGAGCAGTTGGTGCTGGTCCGGCTCCAGCTCCTCCCGGAGCTCCAACCAATTCTTTGCAGTGCATGTTTTGCCGCGTCGTGTGCTCCTCCGAGCTGGAGATGCATTTCCATCTGGCAGCCCATGCACGCCAGTTCCGCTGCCCCTCCTGTCCTGAGACCTTCCACGTGGAGTTCCTCCTAGACCGACACATGCAGAGCCAGCACGGCGGGCCCAAGGATTCCACCAATGGACCCAAGGAGCCCGCCACCAGCTCCTCCCCCAACATGGGCAGTCTCTATGTGAACGCACTACTGCCTCCACTCGCCGCCGCTGCGGCTGCagccgccgctgctgccgccaccaacaacaacagcagcctcCACATTGACTACAACGTGGCTTTCAAGGGGCTCTTTGGAGGTGCAACTGGAGCGGTGGCTCCCACTGGTAAGTTCTACAGTCCGCTGCAGGTAGACACAAGTGGCTTGAAGACACAGCAGACGGCACATCCGCCTCCACATCCGCATCCACATCCAGCCCTGATGTACGGTCTAAGCCAGCGCTATTTGATGGAGATGTACGCGGCCAAGGCTACATCTCCGGCTGCAGCATCTGCTCCGGATGTGcctgtgcagcagcagcagccaccgcAACAGCAGTCAACTGCAGGAGGAGGAACTGCACCCAGTGGCGGTAATAGCTACAGCTGCGGCATGTGCGAACGGCAGGATCTAAGGACCGAGGCGGAACTACATTCGCACCGGAAGTTGGCCCATAACCTCAAGACAGGTGTGAGCCTAAGATGTGCTTACTGCTCGGGTAACTTTAAGTCACGAGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAATGTCTCATCTGCGACGAGATCTTTCCATCGCCCGCGATTCTCGCTGAGCACAAACTGCAGCACTCGAAGGTTGGGCAGTCCGGGAAGTGCGCCCACTGTGGCCAACAGTTGGAGCACGTGGCCGCCTTCCGGGCCCATCTTAGCGAACATGGTAGCGATGGGAATCTGCCCCTGGCCTGCATCTGCTGCCGCCAAACGCTGCACTCGGAATTCGAGTTGAGCCTTCATGCCAAATTCCACACGAAATCACCAGGAGCAGGTGGTAGCCTACAGGAACCCGTCTGTGCGCTGTGTCTAGAACCTTTGCCTGGAGCGGGTGACACGGCTAAGCTGTGCGAGAAGTGTTGTCGCAAACATAACCTGAACGGAAAGCGGAACAAGGAACCAGCTCCAGTCGGTGTACCAGCTCAAGTACCCACGCCGGTTCCAGCAGGTAGCTACTTGGAGAACCGCTGCAATCTCTGCAAGATGATACTGCCGCATGCCCAGAAACTCCAGGAGCATCTCGTGGAGCACACCTTTGCCGGTACCGAGCAGAGAGGCTTCAATTGTTACATCTGCTCAGCCGTGTTTACCGCACCCGCCGGACTCCTGACCCACATTGCCGAGCACGGCGCTCGTCCCTACGACTGCAATCTCTGCCCCGAGAAATTTTACTTTCGTGCCGAGCTTGAGCATCATCAACGTGCCCATGAGCTGAGACCCGCAAATACTGCACGCGTTGCCAAACAGGAGACCCGCAGTTCCTCGGCCAGCTCACCCGTCGCCCTCAGTCCCAGCCATGTCAAGCAGGAGCTCTACGAGCCGGAGACACCCAACTCTCCTGTTACCAACTCCGCCACAGAGGCTTTAGGCCCGGTccaggaggaggaggagtacaTCGAAGTGGAGCAGGTACCGCATGAGATTCGATCCGGGGATCTTCTCTCTGCCGCACAAACGGAGCGTTCCAGCAGTAGCGCTTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTLTPNSHQPHPHSHPQLSGAGEDLGKANGDKVAPIDEEQEREREREREREPPKLKRPAHLHHHYHHQQALKIANKLRKINKEAKLAGTTGAGGGVGGGGGLGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRHALALASDSSPSRLEYPKRGRTQVAATPTPTPMPTPLLRCSYCPKATEFSSLEQLNAHLQLSHEQQARIAPTTTSGRAAGGAGGGGVLGGLVGGDVEGQSNGFQLSCEYCTMKFGNIAALFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLAMELPKIKQDLGSPHRDRERERERELELEKPEQELPTDLSSNKRRGTPPQQQGAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISGSEFNCSANSCGKSFAQSEELQQHLSGEHVVTLLKCTLCSELCETRMAMQLHLACAHSQETKLLRCSACLEIFRSDTDFHVHVKTRHQLPSTQGGAVGAGPAPAPPGAPTNSLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGPKDSTNGPKEPATSSSPNMGSLYVNALLPPLAAAAAAAAAAAATNNNSSLHIDYNVAFKGLFGGATGAVAPTGKFYSPLQVDTSGLKTQQTAHPPPHPHPHPALMYGLSQRYLMEMYAAKATSPAAASAPDVPVQQQQPPQQQSTAGGGTAPSGGNSYSCGMCERQDLRTEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGSDGNLPLACICCRQTLHSEFELSLHAKFHTKSPGAGGSLQEPVCALCLEPLPGAGDTAKLCEKCCRKHNLNGKRNKEPAPVGVPAQVPTPVPAGSYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPANTARVAKQETRSSSASSPVALSPSHVKQELYEPETPNSPVTNSATEALGPVQEEEEYIEVEQVPHEIRSGDLLSAAQTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: iTF_00478915;
80% Identity: -