Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: L
Assembly: GCA_037043435.1
Location: JBAMBK010002069.1:62065-70809[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.2e-05 0.00089 19.8 2.9 1 23 181 203 181 203 0.98

2 17 0.42 31 5.6 6.2 1 23 209 231 209 231 0.97

3 17 2e-07 1.5e-05 25.4 3.2 1 23 237 259 237 259 0.99

4 17 1.5e-05 0.0011 19.6 0.4 1 23 265 287 265 287 0.99

5 17 0.028 2 9.3 0.2 2 23 370 394 369 394 0.90

6 17 0.00046 0.033 14.9 0.6 2 23 422 444 421 444 0.96

7 17 0.033 2.4 9.0 0.7 1 23 530 552 530 552 0.97

8 17 0.0062 0.45 11.3 0.1 2 23 560 581 559 581 0.91

9 17 7.8e-05 0.0057 17.3 0.3 1 23 589 614 589 614 0.94

10 17 5.1 3.7e+02 2.1 1.5 2 23 650 672 649 672 0.94

11 17 0.003 0.22 12.3 1.1 1 23 722 745 722 745 0.97

12 17 0.0019 0.14 12.9 1.8 2 23 936 958 935 958 0.96

13 17 0.14 10 7.1 0.1 1 23 964 986 964 986 0.92

14 17 0.4 29 5.6 0.7 2 23 994 1015 993 1015 0.95

15 17 0.89 65 4.5 0.5 2 23 1116 1137 1116 1137 0.94

16 17 0.038 2.7 8.8 0.0 1 23 1147 1169 1147 1169 0.96

17 17 0.00026 0.019 15.6 1.2 1 23 1174 1196 1174 1196 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.2e-05	0.00089	19.8	2.9	1	23	181	203	181	203	0.98
2	17	0.42	31	5.6	6.2	1	23	209	231	209	231	0.97
3	17	2e-07	1.5e-05	25.4	3.2	1	23	237	259	237	259	0.99
4	17	1.5e-05	0.0011	19.6	0.4	1	23	265	287	265	287	0.99
5	17	0.028	2	9.3	0.2	2	23	370	394	369	394	0.90
6	17	0.00046	0.033	14.9	0.6	2	23	422	444	421	444	0.96
7	17	0.033	2.4	9.0	0.7	1	23	530	552	530	552	0.97
8	17	0.0062	0.45	11.3	0.1	2	23	560	581	559	581	0.91
9	17	7.8e-05	0.0057	17.3	0.3	1	23	589	614	589	614	0.94
10	17	5.1	3.7e+02	2.1	1.5	2	23	650	672	649	672	0.94
11	17	0.003	0.22	12.3	1.1	1	23	722	745	722	745	0.97
12	17	0.0019	0.14	12.9	1.8	2	23	936	958	935	958	0.96
13	17	0.14	10	7.1	0.1	1	23	964	986	964	986	0.92
14	17	0.4	29	5.6	0.7	2	23	994	1015	993	1015	0.95
15	17	0.89	65	4.5	0.5	2	23	1116	1137	1116	1137	0.94
16	17	0.038	2.7	8.8	0.0	1	23	1147	1169	1147	1169	0.96
17	17	0.00026	0.019	15.6	1.2	1	23	1174	1196	1174	1196	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatTCAAGCTACAAAGGAGATTTCAAATAGCgATATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCGGATGGCACCATGACGCCCAACTCAACGCAGCATCCGCATCCAGCTCAGCTCACAGTTGCTGGCGAGGATCCTAGCTCGGAGCAGGCCAAGGCAAATGGAGATTCAGTGACAACTGCAGCTGATGAAGAGCGAGACAGGGagcgagacagagaaagagagagggagccaCTGAAGCTAAAGCGACCCGCTCAtttgcatcatcatcaccatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAACTCACAGGACCcacaggagcaggaggaggaagtggaggcggaggcggaggaggaCATGGTGCAGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAATGCGAATACTGCGCCAAGTTGTTCAAGCACAAACGCTCCCGAGACCGTCATAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCGCATTGCGAGGCCGCTTTCTCCAGAAGTGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGGGGCTACAACACGGCGGCCGCCTTGACTTCGCACATGCAGAAGCACAAGAAGAACGCGGCAATACTGGCCGCAGGGGGCAACCCTAATGCGCTCAACTATAGTCCACGGAGCACAGGTTCGGCCTCCATCTCGAGCAACGGGAGTCTCCACAAGCGACGCTATGCCTTGGCACTCGCCTCCGACAGCAGCCCAAGTCGCATGGAGTATCCGAAGCGGGGACGCGGTCAGGTGGCAACCCAGCCAACGCCCACGGCGACACCCAATCCGACGCCGACGCCCACTCCTCTGCTGCGCTGCAGCTACTGTCCCAAGGTGACGGAGTTCAGCAGCTTGGAGCAGTTGAATGCGCATCTGCAGCAGGCGcacgaacagcagcagcaggcgagGATCAGGACACCTGGAGGAGACCAGGAGACGCAATCGATGCAGTCGAATGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGAGATTCAACAATATTGCCGGACTGTTCCAGCACATGCGCTCCACGCACTTGGATCGCTTGAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGTTTGGCCACCGCGGGCACCTTTAGTCCACGTCTGGCACTGGAGCTGCCCAAGATCAAGCAGGATCTGGGCAGTCCACAGCGGGATCAGGTGATGGAGAAGATGGAGCAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGCACATTGACGCCACCTACGACAATTGTGGCacctccagcagcagcagcagcgccaccTGGCGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCGGACTTTGAAAGCTTTCGCaatcatttgaaaacgcaCATTGCCGAGGGAATGCAACTGATCTGTCCACACTGTGGACTTAGTCTGCCGGAGCAGAGTGAATTTGAGCGCCATGTGGTGGCCCATTTCCTGATCAGCGGCTGTGAGTTCAATTGCAGTGCCTCCAATTGTGGCAAGTCCTTTGCCAAGTCGGAGGAACTGCAGCAGCATCTGAGTAGCGAGCATGTGATGCAGTTGCTCAAGTGCATCATCTGCTCGGAGCTGTGCGAGACGAGGATGGCCATGCAGCTCCATTTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCATGGAGATCTTTCGCACGGATACGGACTTCCATGTGCATGTCAAGACCAGGCATCAGGGAGGAGCGGGAATGGGAGCGGGATCAGCGGGAGGAGTTCTTCCGCCACCTGCTCCTGCGAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTGTGCAACTCGGAGCTGGAGATGCACTTCCATTTGGCGGCACATGCGCGACAATTCCGCTGCCCCTCCTGCCCCGAGACCTTCCACGTGGAGTTTCTGCTGGACAGGCACATGCAGAGCCAGCATGGCGGCGTCAAGGAGTCCCAGGCTAAGGATCCCAGCAGTTCACCCAACATGGGTCTGTATGTGAATGCATTGTTGCCACCTTTGGCGGCAGCTGCCGCAGCTGCTGCGGCGGCGACGtccaaccacaacaacaacaacaacagcaacctgCACATTGACTACAACGTGGCATTCAAGGGACTCTTTGgaggagcagcaggaggaggagctgctgcCACAGGCGGAGGCAAGTTCTACAGTCCGCTGCAGGTGGACACGAGTGGACTGAAGCCACAACAGTCGCCGCATCCGGCTCTGATGTACGGACTCAGTCAGCGCTATCTGATGGAGATGTATGCGGCCAAGGCGACATCTCCGGCGGCGGCCAGTGCTCCGGATGTGCCCCAATCATCATCGGGTGgcactggagctggagctggagcagctgcCAACGCCTTAAGTGGAGGCGgaggcagcggcggcggcaacaGCTACAGTTGTGGCATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAACTCCACTCGCACCGCAAGTTGGCCCACAATCTCAAGACGGGCGTCAGTTTGAGGTGCGCCTATTGCTCGGGCAACTTCAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTCCCCTCGCCCGCAATTCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCGGGGAAGTGTGCCCACTGCGGACAGCAGCTGGAGCACGTGGCCGCCTTTCGGGCCCATCTCACGGAGCACGGCGGCGATGGGAATCTGCCCATGGCGTGCATCTGTTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGTCTTCATGCCAAGTTCCACACCAAGTCGCCAGGTGGCGCTGCTGGTGGCAGCCTCCAGGAGCCAGTCTGCGCCCTGTGCCTGGAGCCGTTGCCGGGCGCTGGAGAAACCGCCAAGTTGTGTGAGAAATGCTGTCGCAAGCATAATCTGAATGGAAAGCGGCCGAAGGAACccgctccagctccagctccagctgcggGTAATGCTGCCTCCTCCACCTACCTGGAGAATCGTTGCAATCTCTGCAAGATGATACTGCCACATGCCCAGAAACTGCAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAGCAGCGTGGCTTCAATTGCTACATCTGCTCCGCCGTCTTCACCGCACCCGCTGGACTCCTCACCCACATTGCCGAGCACGGTGCTCGGCCCTACGACTGCAATCTGTGTCCCGAGAAGTTCTACTTTCGTGCTGAACTGGAGCATCATCAGCGTGCCCATGAGCTGAGACCGtcagctcctcctcctgcgGCGATACGTATCCCGCCCAAGCAGGAGAGGCGCAGCTCCCCGGCCAGCTCACCCCTTGCCCCGAGTCCGAGCCATGTCAAGCAGGAGCTCTACGAATCCGAGACGGCGCCTTCACCCGCCGCCGACGAGCCCTCAGCccaagaggaggaggagtacATTGAAGTGGAGCAGGTACCGCATGAAACACGGTCCGGCGACCTTCTGAATTCCGCACATACCGAACGCTCCAGCAGCAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISNSDMYSTHTSSSYSPSISDGTMTPNSTQHPHPAQLTVAGEDPSSEQAKANGDSVTTAADEERDRERDREREREPLKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPTGAGGGSGGGGGGGHGAAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRGRGQVATQPTPTATPNPTPTPTPLLRCSYCPKVTEFSSLEQLNAHLQQAHEQQQQARIRTPGGDQETQSMQSNGFQLSCEYCTMRFNNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLGSPQRDQVMEKMEQELPTDLSSNKRRTLTPPTTIVAPPAAAAAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISGCEFNCSASNCGKSFAKSEELQQHLSSEHVMQLLKCIICSELCETRMAMQLHLACAHSQETKLLRCSACMEIFRTDTDFHVHVKTRHQGGAGMGAGSAGGVLPPPAPANPLQCMFCRAVCNSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKESQAKDPSSSPNMGLYVNALLPPLAAAAAAAAAATSNHNNNNNSNLHIDYNVAFKGLFGGAAGGGAAATGGGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAASAPDVPQSSSGGTGAGAGAAANALSGGGGSGGGNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLTEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGGAAGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRPKEPAPAPAPAAGNAASSTYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPSAPPPAAIRIPPKQERRSSPASSPLAPSPSHVKQELYESETAPSPAADEPSAQEEEEYIEVEQVPHETRSGDLLNSAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: -
80% Identity: -