Basic Information

Insect: Drosophila neotestacea
Gene Symbol: L
Assembly: GCA_035044365.1
Location: JAWNMD010000050.1:692971-701101[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 1.1e-05 0.00081 19.9 2.9 1 23 166 188 166 188 0.98

2 16 0.37 28 5.6 6.2 1 23 194 216 194 216 0.97

3 16 1.8e-07 1.3e-05 25.5 3.2 1 23 222 244 222 244 0.99

4 16 1.3e-05 0.00099 19.6 0.4 1 23 250 272 250 272 0.99

5 16 0.024 1.9 9.3 0.2 2 23 345 369 344 369 0.90

6 16 0.0012 0.089 13.5 0.2 2 23 400 422 399 422 0.95

7 16 0.029 2.2 9.1 0.7 1 23 504 526 504 526 0.97

8 16 0.0054 0.41 11.4 0.1 2 23 534 555 533 555 0.91

9 16 0.00068 0.052 14.2 0.3 1 23 563 588 563 588 0.94

10 16 0.0027 0.2 12.3 1.1 1 23 697 720 697 720 0.97

11 16 0.0017 0.13 13.0 1.8 2 23 891 913 890 913 0.96

12 16 0.12 9.2 7.1 0.1 1 23 919 941 919 941 0.92

13 16 1.1 88 4.1 1.8 2 23 949 970 948 970 0.95

14 16 0.77 59 4.6 0.5 2 23 1069 1090 1069 1090 0.94

15 16 0.033 2.5 8.9 0.0 1 23 1100 1122 1100 1122 0.96

16 16 0.00023 0.018 15.7 1.2 1 23 1127 1149 1127 1149 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	1.1e-05	0.00081	19.9	2.9	1	23	166	188	166	188	0.98
2	16	0.37	28	5.6	6.2	1	23	194	216	194	216	0.97
3	16	1.8e-07	1.3e-05	25.5	3.2	1	23	222	244	222	244	0.99
4	16	1.3e-05	0.00099	19.6	0.4	1	23	250	272	250	272	0.99
5	16	0.024	1.9	9.3	0.2	2	23	345	369	344	369	0.90
6	16	0.0012	0.089	13.5	0.2	2	23	400	422	399	422	0.95
7	16	0.029	2.2	9.1	0.7	1	23	504	526	504	526	0.97
8	16	0.0054	0.41	11.4	0.1	2	23	534	555	533	555	0.91
9	16	0.00068	0.052	14.2	0.3	1	23	563	588	563	588	0.94
10	16	0.0027	0.2	12.3	1.1	1	23	697	720	697	720	0.97
11	16	0.0017	0.13	13.0	1.8	2	23	891	913	890	913	0.96
12	16	0.12	9.2	7.1	0.1	1	23	919	941	919	941	0.92
13	16	1.1	88	4.1	1.8	2	23	949	970	948	970	0.95
14	16	0.77	59	4.6	0.5	2	23	1069	1090	1069	1090	0.94
15	16	0.033	2.5	8.9	0.0	1	23	1100	1122	1100	1122	0.96
16	16	0.00023	0.018	15.7	1.2	1	23	1127	1149	1127	1149	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGCTATATCGCGGTCCCAGTTCGCGTTTGGAGAACTTAATTGAAAAGATTCAAGCTACAAAAGAGATTTCGAGCAACGATATGTACAGCACGCACACCTCCTCCAGTTACTCGCCAAGTATCTCGGACGGCACATTGACGCCCAACTCGCAACATCCGCATCCAGTTTCTGGCGAGGATCCTAACTCTGATAGGGTCAAATCAAATGGGGATACGGCAACTACAGCTGAAGAGGAGAGAGAACGGGAAAGGGAGAaggaaagagatagagagccACCCAAACTAAAGAGACCGTCACAtttgcatcatcatcatcatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAATTGCGGAAAATCAATAAGGAAGCAAAGCTCACAGGACCCACAGGAGGTGGAGGCGGAAACGGTGGAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGAGCCATGCCGAACACTTGCCTTTCAAATGCGAATACTGCGCCAAGTTATTCAAGCACAAACGTTCCCGAGATCGTCATAAGAAGCTCCATACCAACGAGAGGAACTACAAGTGTCCACATTGTGAGGCCGCTTTCTCCAGAAGTGACCATCTGAAGATCCACATGAAGACGCATGATATTCAGAAGCCCTTCCAGTGTAGTATGTGTAATCGGGGTTATAACACGGCTGCCGCTTTGACCTCGCACATGCAGAAGCATAAGAAGAATGCGGCAATACTGGCAGCTGGTGGCAACCCTAATGCCCTCAACTATAGTCCACGCAGCACAGGCTCTGCCTCCATCTCGAGTAATGGAAGTCTTCACAAGCGACGCTATGCCTTGGCTCTTGCCTCCGACAGCAGTCCAAGTCGTATGGAGTATCCGAAACGTGGGCGTGGTCAAGTGGCAACAACGCCTACTCCAACACCGTTACTACGTTGCAGTTACTGTCCCAAGGTGACGGAGTTCAGCAGTCTGGAGCAATTGAATGCGCACTTGCAACAGGCACATGAACAGCAGACAAGGATCTccacgacaacaacgacaacaactggAGCACCTGGAGGAGATCAGGAGTTGCAATCGAATGGTTTCCAATTGAGTTGCGAATATTGCACCATGAGGTTTGTGAATATTGCTGGATTGTTTCAACATATGCGTGCCACACACTTGGATCGCTTAAGCAGTCCCAACTCCTACTATGAGCACTTTAATCGTCTGGCCACAGCAGGAACTTTCAGTCCAAGATTAGCTCTAGAACTGCCCAAGATCAAGCAAGATTTGAGTAGTCCACAGCAGGAGAAACCGGAACAGGATTTACCCACAGATTTGAGCAGCAATAAAAGACGCACATTGACACCCCCTTCAGCACTAGCACCCCAACAGGCACCAGCACAAGCGCCACCTGGCGTCTTCTTTTGCAATCAATGCAATGCAGGACTCCCGGACTTTGAAAGCTTTCGTAATCATCTAAAAACCCACATAGCCGAGGGCATGCAACTAATCTGTCCCCATTGTGGATTAAGTCTTCCCGAACAGAGTGAATTTGAACGTCATGTGGTTGCCCATTTCTTGATAACCAGCTCCGAGTTTAATTGTAATGCTGGAAGTTGCAACAAATCCTTTGGCAAGTCGGAGGAGTTGCAACAGCATTTGAATAGCGAGCATGTGATTACCGTGCTAAAATGTGGACTATGCTCGGATCTCTGTGAGAACAGGATGGCCATGCAGCTTCATTTGGCCTGTGCCCATAGTCAGGAGACGAAGCTACTGCGTTGCAGCGCCTGCATGGAGATCTTTCGCAATGATACGGATTTCCATGTGCATGTCAAGACCCGACATCATGGAGGAGCTTCAGCAGGTAACGttcctcctgctcctgctgctggtCCTGCTGGTGGACCACCTAATCCTTTGCAGTGCATGTTTTGTCGTGCTGTTTGTTCCTCGGAATTGGAAATGCATTTCCACTTGGCGGCACATGCTCGACAATTTCGTTGCCCCTCCTGCCCCGAAACGTTCCATGTGGAATTCCTGCTGGACAGGCACATGCAGAGTCAACATGGCGGGGTCAAGGAGTCACCCACAAAGGAGCAAAGTTCACCTAACATGGGCAGTCTCTATGTGAATGCATTATTGCCACCACttgcggcagctgcagcagctgctgctgcggcaaccaacaacaacagtagtcTGCACATTGACTACAATGTGGCATTCAAGGGACTCTTTGGAGGAGCTAGTAATGCTGCTACACCCGGTGGTGGTGGCAAGTTCTACAGTCCGTTGCAAGTGGACACAAGTGGATTGAAGCCACAACAATCACCACATCCGGCTCTTATGTACGGACTCAGTCAACGCTATCTGATGGAAATGTACGCGGCTAAAGCGACTTCTCCGGCAGCGGCAAGTGCTCCGGATGTGCCTGTCCAGCAGTCGTCGGGTGCCACAGCGTCTAGTGCCACCAACAGCTTCAGTTGTGGCATGTGTGAGCGTCAGGATTTGAGGAGTGAGGCGGAACTTCATTCACATCGTAAGTTGGCCCACAATTTAAAAACCGGAGTCAGTTTGAGATGCGCCTATTGCTCGGGGAACTTTAAATCCCGAGCAGAGCTGGAGCAGCACATGAAGAGTTGTCACAACTCGAGTGGCAAGCACAAGTGCCTCATTTGCGATGAGATCTTTCCGTCTCCGGCCATTCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTTGGACAATCCGGAAAGTGTGCCCATTGTGGACACCAGTTGGAGCACGTAGCCGCCTTCCGAGCTCATTTAACCGAGCACGGAAGTGATGGTAATCTTCCGATGGCCTGCATCTGTTGCCGCCAGACTCTACACTCGGAGTTCGAGTTGAGTCTCCATGCCAAGTTCCACACCAAGTCTCCGAGTGGTGGTGGAAGTCTCCAGGAACCGGTTTGTGCCCTGTGCTTGGAACCATTGCCTGGAGCCGGAGAAACTGCCAAATTGTGTGAGAAATGCTGTCGCAAGCATAATCTCAATGGAAAGCGGAACAAGGAGGCAGCTCCTACTATAGGAGCAGCTGCTCCACAAAATGCCGCCTCCACCTACTTGGAAAACCGTTGTAATCTCTGCAAAATGATCTTGCCACATGCCCAGAAGCTACAGGAGCATCTTGTGGAACACACCTTTGCCGGCACCGAACAGCGTGGATTCAATTGTTATATCTGCTCTGCCGTATTCACCGCACCAGCCGGACTCCTGACCCACATTGCCGAGCACGGTGCTCGTCCCTATGACTGCAACCTGTGTCCCGAGAAATTCTACTTTCGCGCCGAACTGGAACATCATCAGCGTGCCCATGAACTGAGACCGGCGCCTCCTTCAGCTGGACGGATTCCTCCCAAGCAGGAGACTCGCAGCTCCTCGGCCAGCTCACCCATGGCACTGAGTCCTAGCCATGTCAAGCAGGAGCTCTATGAATCCGAGACGGCGGCCTCTCCCGCCGCAGAGCCATCAGCCCCGGAAGATGAGGAATACATTGAAGTGGAGCAAGTGCCGCATGAAACCCGTTCCGGAGATCTTCTCACTTCCGCACACACTGAACGTTCCAGTAGCAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISSNDMYSTHTSSSYSPSISDGTLTPNSQHPHPVSGEDPNSDRVKSNGDTATTAEEEREREREKERDREPPKLKRPSHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPTGGGGGNGGATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRGRGQVATTPTPTPLLRCSYCPKVTEFSSLEQLNAHLQQAHEQQTRISTTTTTTTGAPGGDQELQSNGFQLSCEYCTMRFVNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLSSPQQEKPEQDLPTDLSSNKRRTLTPPSALAPQQAPAQAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLITSSEFNCNAGSCNKSFGKSEELQQHLNSEHVITVLKCGLCSDLCENRMAMQLHLACAHSQETKLLRCSACMEIFRNDTDFHVHVKTRHHGGASAGNVPPAPAAGPAGGPPNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKESPTKEQSSPNMGSLYVNALLPPLAAAAAAAAAATNNNSSLHIDYNVAFKGLFGGASNAATPGGGGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAASAPDVPVQQSSGATASSATNSFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLTEHGSDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSGGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKEAAPTIGAAAPQNAASTYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPAPPSAGRIPPKQETRSSSASSPMALSPSHVKQELYESETAASPAAEPSAPEDEEYIEVEQVPHETRSGDLLTSAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: iTF_00583985;
80% Identity: -