Basic Information

Insect: Drosophila arawakana
Gene Symbol: L
Assembly: GCA_018151165.1
Location: JAECWX010000210.1:1547202-1556489[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.2e-05 0.00067 19.8 2.9 1 23 171 193 171 193 0.98

2 17 0.4 23 5.5 6.2 1 23 199 221 199 221 0.97

3 17 1.9e-07 1.1e-05 25.4 3.2 1 23 227 249 227 249 0.99

4 17 1.4e-05 0.00082 19.5 0.4 1 23 255 277 255 277 0.99

5 17 0.035 2 8.9 0.1 2 23 354 378 353 378 0.94

6 17 0.0025 0.14 12.5 0.2 2 23 418 440 417 440 0.95

7 17 0.031 1.8 9.0 0.7 1 23 531 553 531 553 0.97

8 17 0.0059 0.34 11.3 0.1 2 23 561 582 560 582 0.91

9 17 0.00019 0.011 16.0 0.1 1 23 590 615 590 615 0.91

10 17 1.2 72 4.0 1.3 2 23 651 673 650 673 0.95

11 17 0.0029 0.17 12.3 1.1 1 23 725 748 725 748 0.97

12 17 0.0019 0.11 12.9 1.8 2 23 947 969 946 969 0.96

13 17 0.13 7.5 7.1 0.1 1 23 975 997 975 997 0.92

14 17 0.29 17 6.0 0.6 2 23 1005 1026 1004 1026 0.96

15 17 0.85 49 4.5 0.5 2 23 1127 1148 1127 1148 0.94

16 17 0.041 2.4 8.6 0.0 1 23 1158 1180 1158 1180 0.96

17 17 0.00025 0.015 15.6 1.2 1 23 1185 1207 1185 1207 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.2e-05	0.00067	19.8	2.9	1	23	171	193	171	193	0.98
2	17	0.4	23	5.5	6.2	1	23	199	221	199	221	0.97
3	17	1.9e-07	1.1e-05	25.4	3.2	1	23	227	249	227	249	0.99
4	17	1.4e-05	0.00082	19.5	0.4	1	23	255	277	255	277	0.99
5	17	0.035	2	8.9	0.1	2	23	354	378	353	378	0.94
6	17	0.0025	0.14	12.5	0.2	2	23	418	440	417	440	0.95
7	17	0.031	1.8	9.0	0.7	1	23	531	553	531	553	0.97
8	17	0.0059	0.34	11.3	0.1	2	23	561	582	560	582	0.91
9	17	0.00019	0.011	16.0	0.1	1	23	590	615	590	615	0.91
10	17	1.2	72	4.0	1.3	2	23	651	673	650	673	0.95
11	17	0.0029	0.17	12.3	1.1	1	23	725	748	725	748	0.97
12	17	0.0019	0.11	12.9	1.8	2	23	947	969	946	969	0.96
13	17	0.13	7.5	7.1	0.1	1	23	975	997	975	997	0.92
14	17	0.29	17	6.0	0.6	2	23	1005	1026	1004	1026	0.96
15	17	0.85	49	4.5	0.5	2	23	1127	1148	1127	1148	0.94
16	17	0.041	2.4	8.6	0.0	1	23	1158	1180	1158	1180	0.96
17	17	0.00025	0.015	15.6	1.2	1	23	1185	1207	1185	1207	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGCTTTATCGCGGTCCCAGCTCGCGCTTAGAGAATTTAATTGAGAAGATTCAAGCCACTAAGGAGATTTCCAATAACGACATGTACAGCACACACACCTCCTCGAGCTACTCGCCCAGCATTTCGGATGGCACACTGACGCCCAACTCGCACCAGCCGCATCCGCATTCGCATGCACAGCTCACAGGTGCTGGCGAGGATCTGGGCAAAGCAAATGGGAATACGGCAGCTCCTATCGATGACGAACGCGAGAGAGAAAGGGATAGGGAGCGGGAACGGGAGCCAACCAAATTAAAGCGACCCGCCCACTTACATCATCATTATCATCATCAGCAAGCGTTGAAGATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCGAAACTCGCAGGACCCACAGGACAAGCAGGAGTCGGAAGTGGAGGAGGACTTGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGTATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGCCTCGGTTACTTGAAGCATCACGTCCAGAGCCACGCCGAGCATTTGCCATTCAAATGCGAATACTGCGCCAAATTATTCAAGCACAAACGCTCCCGAGATCGCCATAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCACACTGCGAGGCCGCTTTCTCCAGAAGTGACCACCTGAAGATTCACATGAAGACCCATGACATACAGAAGCCCTTCCAGTGCAGCATGTGCAATAGGGGCTACAACACGGCTGCGGCACTGACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCAATACTGGCCGCAGGTGGCAACCCTAATGCACTCAACTACAGTCCACGCAGCACTGGATCTGCCTCCATCTCCAGCAACGGCAGTCTACACAAACGACGCTACGCCCTGGCGCTGGCCTCCGATAGCAGCCCCAGTCGCCTTGAGTACCCCAAACGTGGGCGTAACCAAGTAGCTGCCACGCCCACACATACGCCTACGCCTACGCCGCTGCTGCGCTGCAGTTACTGTCCCAATGCGACGGAGTTTAGCAGCCTGGAGCAGCTAAATGCACACCTGCAGTTGGCACATGAGCCGCAGGCGAGGATTGTGACCACTAGCGCGTCGGGTAGAGCAGGGGGTGGGGCAGCAGGAGAGGGAGTGGGAGTGGCAGGAGATGTGGAGAGCCAGTCCAATGGGTTCCAGCTTAGCTGCGAGTACTGCACCATGAGGTTTGGCAATATTGCCGCTCTCTTTCAACACATGCGAGCCACGCATCTGGATCGTCTGAGCAGTCCCAACTCGTACTACGAGCACTTCAATCGCCTGGCCACTGCAGGGACTTTTAGTCCACGACTGGCCATGGAGCTGCCCAAAATAAAGCAGGATCTAGGCAGTCCACAGCGGGAGAGGGAGAGGGAGAGGGAGCGTGAACGGGAGCGCGAGCGTGAGCGGGAACGTGAACTGGAGCTAGAGAAGCCGGAGCAGGAGCTGCCAACGGATTTGAGCAGCAACAAGCGCAGGAGCACACCAGCGCCACCTGGCGTCTTCTTCTGCAACCAATGCAATGCGGGTCTGCCCGACTTTGAGAGCTTCCGGAATCATCTGAAGACACACATAGCCGAGGGCATGCAGCTAATCTGTCCCCACTGCGGTCTCAGTCTGCCCGAGCAGAGCGAGTTCGAGCGCCATGTGGTGGCCCATTTCCTGATCTCCGGCAGCGAGTACAACTGCAGTGCCAGCAGCTGTGGCAAATCATTTGCGCAGTCGGAGGAACTGCAGCAGCATTTGATTGGGGAGCATGTGGTCACGCTGCTCAAGTGCACGCTCTGCTCGGAGCTTTGCGAGACCAGAATGGCCATGCAGCTGCATCTGGCCTGCGCCCACAGCCAGGAGACAAAGCTGCTACGCTGCAGCGCCTGCCTGGAGATCTTTCGTAGCGACACCGACTTCCATGTGCACGTCAAGACACGTCACCAGCTGCCGAGTAGCCAAGGAGTAGCAGTTGGTGCTGTTCCGGCTCAAGCGCCTAGCGGAGCGCCAGCTAATCCACTGCAGTGCATGTTCTGCCGCGTCGTGTGCTCCTCGGAGCTGGAGATGCACTTCCATCTGGCAGCCCATGCGCGCCAGTTCCGCTGCCCCTCCTGTCCCGAGACCTTCCACGTGGAGTTCCTGCTGGACCGACACATGCAGAGCCAGCACGGTGGACCCAAGGACGCCAGCAATGGACCCAAGGAGCCCGGCAACAGCAGCACATCCCCCAACATGGGCAGTCTCTATGTGAACGCACTGCTGCCGCCACTCGCCGCCGCTGCCGCTGCAGCCGCCGCAGCTGCCGCCAATGCCAACGCCAGCAACAACAACAACAGCAGCCTCCACATCGACTACAACGTGGCCTTCAAGGGGCTCTTCGGTGCAGGCGGCGCGGTGGCTCCCACTGGCAAGTTCTACAGTCCGCTGCAGGTGGACACCAGTGGCTTGAAGCCACAGGCACAGCAGACACCACATGCGCCGCCACATCCGCATCCACATCCAGCGCTCATGTACGGTCTGAGCCAGCGCTATCTGATGGAGATGTATGCGGCCAAGGCGACATCTCCGGCTGCAGCTGCTGCTCCGGATGTGCCTGTCCAGCAGCAGCCGGCGCAGCAGCAGTCGACGGCCGGTGGCGGCACTGCGTCCAGTGGCGGCAACAGCTACAGCTGCGGCATGTGCGAGCGTCAGGATCTAAGAAGCGAGGCGGAACTCCACTCACACCGCAAGTTGGCCCACAATCTCAAGACGGGCGTGAGCCTGAGATGTGCTTACTGCTCGGGTAACTTTAAGTCGCGTGCGGAGCTGGAGCAGCACATGAAAAGCTGCCACAATTCGAGTGGCAAGCACAAATGTCTCATCTGCGATGAGATCTTTCCATCGCCCGCAATACTCGCTGAGCACAAGCTGCAGCATTCGAAGGTTGGGCAGTCCGGCAAGTGCGCCCACTGTGGGCAACAGCTGGAGCACGTCGCCGCCTTCCGTGCGCATCTTAGTGAGCATGGCGGCGATGGGAATCTGCCGCTGGCCTGCATCTGCTGCCGCCAGACACTGCATTCGGAGTTCGAGCTGAGCCTGCATGCCAAATTCCACACAAAGTCTCCTGGCGCTGGTGGCAGCCTCCAGGAGCCCGTCTGTGCGCTATGCCTGGAGCCTTTGCCCGGCGCTGGTGACACCGCCAAGCTGTGCGAGAAGTGTTGTCGCAAACACAACCTCAACGGTAAGCGTAACAAGGAACCAGTCGCGCTGGGTGTGCCAGCTCAAGCTCCAGCGCCAGTGCCAGCCGGTAGCTACTTGGAGAATCGTTGCAATCTCTGCAAGATGATACTGCCGCATGCCCAGAAACTGCAGGAGCATCTCGTGGAGCACACATTTGCCGGCACCGAGCAGCGTGGTTTCAATTGTTACATCTGCTCCGCGGTGTTCACCGCACCCGCCGGACTGCTGAGCCACATTGCCGAGCACGGTGCTCGTCCCTACGACTGCAATCTGTGCCCCGAAAAGTTTTACTTTCGCGCCGAACTAGAGCATCATCAACGTGCCCACGAGCTGAGACCCACAAATGCTGCACGCGTGGCCAAGCAGGAGACTCGCAGCACCTCGGCCAGCTCACCCATCGCTCTCAGTCCCAGTCATGTCAAGCAGGAGCTCTACGAACCAGAGACCTCCAACTCACCCGCTGCCAACGACAACACAGCGCACTCTGGCCCGGCTCAGGAGGAGGAGGAGTACATCGAAGTGGAGCAGGTGCCACACGAGACTCGCTCCGGAGAACTGCTGTCCTCCGCACAAACAGAGCGCTCTAGTAGTAGCGCTTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTLTPNSHQPHPHSHAQLTGAGEDLGKANGNTAAPIDDERERERDREREREPTKLKRPAHLHHHYHHQQALKIANKLRKINKEAKLAGPTGQAGVGSGGGLGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEYPKRGRNQVAATPTHTPTPTPLLRCSYCPNATEFSSLEQLNAHLQLAHEPQARIVTTSASGRAGGGAAGEGVGVAGDVESQSNGFQLSCEYCTMRFGNIAALFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLAMELPKIKQDLGSPQRERERERERERERERERERELELEKPEQELPTDLSSNKRRSTPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISGSEYNCSASSCGKSFAQSEELQQHLIGEHVVTLLKCTLCSELCETRMAMQLHLACAHSQETKLLRCSACLEIFRSDTDFHVHVKTRHQLPSSQGVAVGAVPAQAPSGAPANPLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGPKDASNGPKEPGNSSTSPNMGSLYVNALLPPLAAAAAAAAAAAANANASNNNNSSLHIDYNVAFKGLFGAGGAVAPTGKFYSPLQVDTSGLKPQAQQTPHAPPHPHPHPALMYGLSQRYLMEMYAAKATSPAAAAAPDVPVQQQPAQQQSTAGGGTASSGGNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGGDGNLPLACICCRQTLHSEFELSLHAKFHTKSPGAGGSLQEPVCALCLEPLPGAGDTAKLCEKCCRKHNLNGKRNKEPVALGVPAQAPAPVPAGSYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPTNAARVAKQETRSTSASSPIALSPSHVKQELYEPETSNSPAANDNTAHSGPAQEEEEYIEVEQVPHETRSGELLSSAQTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: iTF_00569166; iTF_00471067;
80% Identity: -