Basic Information

Insect: Drosophila ustulata
Gene Symbol: L
Assembly: GCA_035047365.1
Location: JAWNPT010000057.1:46710830-46719934[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00077 19.8 2.9 1 23 185 207 185 207 0.98

2 17 0.39 27 5.5 6.2 1 23 213 235 213 235 0.97

3 17 1.9e-07 1.3e-05 25.4 3.2 1 23 241 263 241 263 0.99

4 17 1.4e-05 0.00094 19.5 0.4 1 23 269 291 269 291 0.99

5 17 0.48 32 5.2 0.1 2 23 377 401 376 401 0.85

6 17 0.089 6 7.6 0.3 2 23 428 450 427 450 0.94

7 17 0.031 2.1 9.0 0.7 1 23 533 555 533 555 0.97

8 17 0.0058 0.39 11.3 0.1 2 23 563 584 562 584 0.91

9 17 0.00011 0.0077 16.6 0.1 1 23 592 617 592 617 0.91

10 17 5.8 3.9e+02 1.9 1.6 2 23 653 675 652 675 0.95

11 17 0.0028 0.19 12.3 1.1 1 23 737 760 737 760 0.97

12 17 0.0018 0.12 12.9 1.8 2 23 946 968 945 968 0.96

13 17 0.13 8.7 7.1 0.1 1 23 974 996 974 996 0.92

14 17 2.5 1.7e+02 3.0 1.7 2 23 1004 1025 1004 1025 0.93

15 17 0.83 56 4.5 0.5 2 23 1128 1149 1128 1149 0.94

16 17 0.035 2.4 8.8 0.0 1 23 1159 1181 1159 1181 0.96

17 17 0.00036 0.024 15.1 1.1 1 23 1186 1208 1186 1208 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00077	19.8	2.9	1	23	185	207	185	207	0.98
2	17	0.39	27	5.5	6.2	1	23	213	235	213	235	0.97
3	17	1.9e-07	1.3e-05	25.4	3.2	1	23	241	263	241	263	0.99
4	17	1.4e-05	0.00094	19.5	0.4	1	23	269	291	269	291	0.99
5	17	0.48	32	5.2	0.1	2	23	377	401	376	401	0.85
6	17	0.089	6	7.6	0.3	2	23	428	450	427	450	0.94
7	17	0.031	2.1	9.0	0.7	1	23	533	555	533	555	0.97
8	17	0.0058	0.39	11.3	0.1	2	23	563	584	562	584	0.91
9	17	0.00011	0.0077	16.6	0.1	1	23	592	617	592	617	0.91
10	17	5.8	3.9e+02	1.9	1.6	2	23	653	675	652	675	0.95
11	17	0.0028	0.19	12.3	1.1	1	23	737	760	737	760	0.97
12	17	0.0018	0.12	12.9	1.8	2	23	946	968	945	968	0.96
13	17	0.13	8.7	7.1	0.1	1	23	974	996	974	996	0.92
14	17	2.5	1.7e+02	3.0	1.7	2	23	1004	1025	1004	1025	0.93
15	17	0.83	56	4.5	0.5	2	23	1128	1149	1128	1149	0.94
16	17	0.035	2.4	8.8	0.0	1	23	1159	1181	1159	1181	0.96
17	17	0.00036	0.024	15.1	1.1	1	23	1186	1208	1186	1208	0.97

Sequence Information

Coding Sequence: ATGATGGccttaaaaatgttatatcGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatTCAAGCCACGAAGGAGATATCCAATAACGACATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCGGACGGCACTTTGACGCCCAACTCCCAGCAGCCGCATCCGCAGCTGTTGGCGGCTGGCGAGGATCCGGGCTCCGAGCCGTCCAAGGCGAATGGCGACGCCTCGACAGCAGCCGACGAGGACCGAGAGCCTCAaagggagcgggagcgggaacGGGATCCACCCAAGCTGAAGCGACCCGCCCACTtgcatcatcaccatcatcattaCCATCACCAGCAGGCGCTGAAAATTGCCAACAAGTTGCGTAAAATCAATAAGGAAGCAAAGCTCACAGGACCCGCAGCAGGAGGCGGAGCAGGAGGGGGAGgcggagggggaggaggaggaggcggaggtgGCAACACTGGCGCAGCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGCCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGCGACAAATCATTTCCACGACTCGGCTACTTGAAGCATCACGTCCAGAGCCACGCCGAGCATTTGCCTTTTAAATGCGAGTACTGCGCCAAGTTATTCAAGCACAAGCGCTCCCGCGATCGCCACAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCGCACTGCGAAGCCGCTTTCTCCAGAAGCGACCATCTAAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACAGCCGCCGCGCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCCATCCTGGCGGCCGGCGGCAACCCCAACGCCCTCAACTACAGCCCGCGCAGCACGggctccgcctccgcctcggCCTCGCTGTCgagccacagcaacggcagtctgcacaagcggcGCTATGCGCTGGCGCTCGCCTCCGACAGCAGTCCCAGTCGCCTGGAGTACCCGAAGCGCAGTCGAGGACACCACGTGGCcaccacgcccacgcccacagGCACGCCCATGGGCACGCCGCTGCTGCGGTGCAGCTACTGCCCCAAGGCGGTCGAGTTCGGCAGCCTGGAGCAGCTGAACGCGCATCTGCAGCAGGCGCACGACCAGAAGGcgccagacggacagacggaagCGGGCGAGGATGGcaagggacagggacaggcgAATGGCTTCCAGCTGAGCTGCGAGTACTGCACGATGCGGTTCCTGAACATCGCCGGGCTGTTCCAGCACATGCGGGCCACGCACCTGGACCGGCTGAGCAGTCCCAACTCCTACTACGAGCACTTCAACCGCCTGGCCACGGCGGGCACGTTCAGTCCGCGGCTGGCGCTGGAGCTGCCCAAGATCAAGCCGGATCTGGGCAGTCCGCCGCTGCCGAAGCCGGAGCAGGAGCTGCCCACGGACCTGAGCAGCAACAAGCGGCGCACGATGACCCCgccaggaggaggaggagcaatCGCTGCCGCTccagcgccgccgccgccgggcGTCTTCTTCTGCAACCAGTGCAACGCGGGGCTGCCGGACTTCGAGAGCTTCCGCAACCATCTGAAGACGCACATTGCCGAGGGCATGCAGCTGATCTGTCCGCACTGCGGCCTCAGTCTGCCCGAGCAGAGCGAGTTCGAGCGCCACGTGGTCGCCCACTTCCTGATCGCGGGCTGCGAGTTCAACTGCGGCGCCGCCAGCTGCGGCAAGTCCTTCGCCAAGTCGgacgagctgcagcagcacctCAACAGCGAGCACGTGGTCACGCTGCTCAAGTGCGCGCTCTGCGCCGAGATCTGCGAGACGCGGATGGCGATGCAGCTGCATCTGGCCTGCGCCCACGGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCTTGGAGCTCTTCCGCAACGACACCGACTTCCATGTGCACGTGAAGACGCGCCATCAGCTGGCCAGCGGCCACCAGGCTCCTCCGCCGCCCACAGCCCCGCCTGGCCACGGACACGGTCAGGGACACGGTCAGGGGCACGGTCAGGGACAGGCGAATCCCCTGCAGTGCATGTTCTGCCGCGCCGTCTGCTCCTCGGAGCTGGAGATGCACTTCCACCTGGCGGCGCACGCTCGCCAGTTCCGCTGCCCCTCCTGTCCCGAGACCTTCCACGTCGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCGTCAAGGAGCGCAGTCCCGTCAAGGAGACCTCCCCCAGCATGGGCAGCCTCTACGTGAACGCCCTGCTGCCGCCcctggcagctgctgcggccgccgccgccgccgccgcgaccaacaacaacagcagcctcCACATCGACTACAACGTGGCCTTCAAGGGCCTCTTCGGTGGGGCAGGCGCTCCCTCCGGAGCCGCTgcgggcggcggcggcaagtTCTACAGCCCGCTGCAGGTGGACACGAGCGGCCTGAAGCCGCAGCAGTCGCCGCACCCCGCGCTGATGTACGGCCTCAGCCAGCGCTACCTCATGGAGATGTACGCCGCCAAGGCGACCTCCCCGGCGGCAGCCAGCGCCCCCGAAGTGCCCGTCCAGCCGCAGCCTCAGTCCCAggcgcagtcgcagtcgcagacAGCCGGTGGAGGCAATTCGGGAGTGACGAGCGGCAGCTACAGCTGCGGGATGTGCGAGCGGCAGGATCTGCGCAGCGAGGCGGAGCTGCACTCGCACCGCAAGCTGGCGCACAACCTGAAGACGGGGGTGAGCCTGCGGTGCGCCTACTGCTCGGGCAACTTCAAGTCGCGGGcggagctggagcagcacaTGAAGAGCTGCCACAACTCGAGTGGGAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATTCTCGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGCGCCCACTGCGGCCACCAGCTGGAGCACGTGGCCGCCTTCCGCGCCCACCTCGGCGAGCACGGCGGCGACGGCAACCTGCCCATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCCGAGTTCGAGCTCAGCCTGCACGCCAAGTTCCACACGAAGTCcgccggcggcggcggcgccagTCTCCAGGAGCCGGTCTGCGCCCTCTGCCTGGAGCCACTGCCCGGGGCCGGAGACACCGCCAAGCTGTGCGACAAGTGCTGTCGCAAGCACAACCTCAATCTcaatggcaacggcagcggcaagcGGAGCAAGGAGTCTGCTGTGGCTCCTGCGGCACCTCCAGTCCCCTCCAGCTACCTGGAGAACCGCTGCAACCTCTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAGGAGCACCTCGTGGAGCACACGTTCGCCGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCGGTCTTCACCGCACCCGCGGGCCTTCTCACCCACATCGCCGAGCACGGGGCTCGACCCTACGACTGCAGCCTCTGTCCCGAGAAGTTCTACTTCCGCGCCGAGCTGGAGCACCATCAGCGTGCCCACGAGCTGAGGCCAGCTCCAGTGCCAGTTCCAATTCCTGCTCCGCCAGCGACTCGCGTGCCCAAGCAGGAGGTCCGCAGCTCCTCGGCCTCAGCGTCGGCTTCGGCGAGTTCGCCACTCGCCCTCAGTCCGAGCCACGTTAAGCAGGAGCTGTACGAGTCCGAGACGGCTCCCTCGCCCCCCGCCACGGAGGCGCCCGTCCAAGACGACGAGGAGTACATCGAGGTGGAGCAGATGCCGCTCGAGACCCGCTCCGGAGATCTGTTGGCTGCCTCGCACACCGAAcgctccagcagcagcgcctAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTLTPNSQQPHPQLLAAGEDPGSEPSKANGDASTAADEDREPQRERERERDPPKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPAAGGGAGGGGGGGGGGGGGGNTGAAAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASASLSSHSNGSLHKRRYALALASDSSPSRLEYPKRSRGHHVATTPTPTGTPMGTPLLRCSYCPKAVEFGSLEQLNAHLQQAHDQKAPDGQTEAGEDGKGQGQANGFQLSCEYCTMRFLNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPPLPKPEQELPTDLSSNKRRTMTPPGGGGAIAAAPAPPPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLIAGCEFNCGAASCGKSFAKSDELQQHLNSEHVVTLLKCALCAEICETRMAMQLHLACAHGQETKLLRCSACLELFRNDTDFHVHVKTRHQLASGHQAPPPPTAPPGHGHGQGHGQGHGQGQANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKERSPVKETSPSMGSLYVNALLPPLAAAAAAAAAAATNNNSSLHIDYNVAFKGLFGGAGAPSGAAAGGGGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAASAPEVPVQPQPQSQAQSQSQTAGGGNSGVTSGSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLGEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSAGGGGASLQEPVCALCLEPLPGAGDTAKLCDKCCRKHNLNLNGNGSGKRSKESAVAPAAPPVPSSYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCSLCPEKFYFRAELEHHQRAHELRPAPVPVPIPAPPATRVPKQEVRSSSASASASASSPLALSPSHVKQELYESETAPSPPATEAPVQDDEEYIEVEQMPLETRSGDLLAASHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: iTF_00509320;
80% Identity: -