Basic Information

Insect: Drosophila phalerata
Gene Symbol: L
Assembly: GCA_951394115.2
Location: OY729850.1:11090791-11099122[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.0011 19.8 2.9 1 23 184 206 184 206 0.98

2 17 0.38 37 5.6 6.2 1 23 212 234 212 234 0.97

3 17 1.8e-07 1.8e-05 25.4 3.2 1 23 240 262 240 262 0.99

4 17 1.3e-05 0.0013 19.6 0.4 1 23 268 290 268 290 0.99

5 17 0.025 2.5 9.3 0.2 2 23 371 395 370 395 0.90

6 17 0.0012 0.12 13.4 0.2 2 23 418 440 417 440 0.95

7 17 0.03 2.9 9.0 0.7 1 23 529 551 529 551 0.97

8 17 0.0083 0.82 10.8 0.1 2 23 559 580 558 580 0.91

9 17 2.5e-05 0.0025 18.7 0.3 1 23 588 613 588 613 0.93

10 17 4.7 4.6e+02 2.1 1.5 2 23 649 671 648 671 0.94

11 17 0.0027 0.27 12.3 1.1 1 23 722 745 722 745 0.97

12 17 0.0018 0.17 12.9 1.8 2 23 929 951 928 951 0.96

13 17 0.12 12 7.1 0.1 1 23 957 979 957 979 0.92

14 17 0.27 27 6.0 0.6 2 23 987 1008 986 1008 0.96

15 17 0.8 79 4.5 0.5 2 23 1107 1128 1107 1128 0.94

16 17 0.034 3.3 8.9 0.0 1 23 1138 1160 1138 1160 0.96

17 17 0.00024 0.024 15.6 1.2 1 23 1165 1187 1165 1187 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.0011	19.8	2.9	1	23	184	206	184	206	0.98
2	17	0.38	37	5.6	6.2	1	23	212	234	212	234	0.97
3	17	1.8e-07	1.8e-05	25.4	3.2	1	23	240	262	240	262	0.99
4	17	1.3e-05	0.0013	19.6	0.4	1	23	268	290	268	290	0.99
5	17	0.025	2.5	9.3	0.2	2	23	371	395	370	395	0.90
6	17	0.0012	0.12	13.4	0.2	2	23	418	440	417	440	0.95
7	17	0.03	2.9	9.0	0.7	1	23	529	551	529	551	0.97
8	17	0.0083	0.82	10.8	0.1	2	23	559	580	558	580	0.91
9	17	2.5e-05	0.0025	18.7	0.3	1	23	588	613	588	613	0.93
10	17	4.7	4.6e+02	2.1	1.5	2	23	649	671	648	671	0.94
11	17	0.0027	0.27	12.3	1.1	1	23	722	745	722	745	0.97
12	17	0.0018	0.17	12.9	1.8	2	23	929	951	928	951	0.96
13	17	0.12	12	7.1	0.1	1	23	957	979	957	979	0.92
14	17	0.27	27	6.0	0.6	2	23	987	1008	986	1008	0.96
15	17	0.8	79	4.5	0.5	2	23	1107	1128	1107	1128	0.94
16	17	0.034	3.3	8.9	0.0	1	23	1138	1160	1138	1160	0.96
17	17	0.00024	0.024	15.6	1.2	1	23	1165	1187	1165	1187	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatTCAAGCCACTAAGGAGATTTCAAATAACGATATGTACAGCACTCACACCTCCTCCAGCTACTCGCCGAGCATCTCGGACGGCACATTGACGCCCAACTCGCAGCATCCACAtccgcatccacatccacattcacaGCTCTCAGCTGCTGGTGAGGATCCTAGCTCCGAGCAGGCCAAGGCGAATGGCGACACGGCAACAGCGGCTGATGaggagcgagagcgagagagggagagggagagagagccAGCGAAACTAAAGCGACCCGCTCAtttgcatcatcatcatcatcattatcatcatcagcagGCGCTGAAAATAGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAACTCACAGGACCCACAGGAGCAGGAACAGCAGGCGGAGCaggaggtggaggaggaggaggaggacaTGGTGCAGCGACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGAGCCATGCCGAACATTTGCCTTTCAAATGCGAATACTGCGCCAAGTTATTCAAGCACAAACGTTCCCGAGACCGTCATAAGAAGCTCCATACCAACGAAAGGAACTACAAGTGTCCGCATTGCGAGGCCGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACCCACGATATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGGGGCTACAACACGGCGGCCGCCTTGACCTCGCACATGCAGAAGCATAAGAAGAATGCGGCAATACTGGCAGCTGGTGGCAACCCCAATGCCCTCAACTACAGTCCACGTAGCACGGGATCTGCCTCCATCTCCAGCAatgggagtctccacaagcGACGCTATGCATTGGCACTCGCCTCCGACAGCAGTCCCAGTCGAATGGAGTATCCGAAACGTGGTCGTGGTCAGGTGGCAACCACACCCGTATCGACACCGatacccacacccacaccgaCTCCGTTGCTCCGTTGCAGCTACTGTCCCAAGGTGACGGAGTTTAGCAGCTTGGAGCAATTGAATGCACATCTGCAGCAGGCACATGAGCAGGCGAGGATTACGACGCCTGGCGGAGATGTGGAGACGATGCAGTCGAATGGCTTCCAGTTGAGCTGCGAGTACTGCACCATGAGATTCGTGAATATCGCTGGATTGTTCCAGCACATGCGTGCCACGCACCTGGATCGCCTGAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGTCTGGCCACGGCGGGCACATTCAGTCCACGTCTGGCACTGGAGCTGCCCAAGATTAAGCAGGATTTGAGCAGTCCACAGCAGCGGGAACAGCGGGAGCAGCGGGAACATCTCATGGAGAAGCCGGAACAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGCACAGTGACACCACCAACAACAGTGGTTGCTACTCAAGCGCCACCTGGCGTCTTCTTTTGCAATCAATGCAATGCCGGTCTGCCGGACTTTGAAAGCTTCCGGAATCATCTGAAGACACACATAGCCGAAGGCATGCAACTGATCTGTCCACATTGTGGACTAAGTCTACCGGAGCAGAGTGAATATGAACGCCATGTGGTTGCCCATTTCCTGATCACCAGCTCCGAGTTCAATTGCAGTGCCGGCAGCTGTGGCAAATCCTTCAGCAAGTCGGATGAACTGCAGCAGCATTTGAATAGCGAGCATGTGATGACGCTGCTCAAGTGCATCCTCTGCTCGGAGCTGTGCGAATCCAGGATGGCCATGCAGCTCCACTTGGCCTGTGCACACAGTCAGGAGACGAAGCTGTTGCGTTGCAGCGCCTGCATGGAGATCTTTCGCAATGATACGGACTTCCATGTGCATGTCAAGACCCGGCATCAAGGTGGCAACGGTGGCGGAGGAGTGGGAGTGGCAGGAGGAGTCGGAGGCGGAGCTGTATCTGCCAATCCCTTGCAGTGCATGTTCTGTCGCGCCGTTTGCAACTCGGAGCTGGAGATGCACTTCCATCTGGCGGCACATGCGCGTCAATTCCGTTGCCCCTCCTGCCCCGAAACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGTCAGCACGGCGGCGTCAAGGAGTCGCCGACCAAGGAACCCAGCAGCTCACCCAACATGGGCAGTCTGTATGTGAATGCCTTGTTGCCACCGCTTGCGGCAGCTGCagccgctgctgctgtggcaaccaacaacaacagcaatctgCATATTGACTACAATGTGGCATTCAAGGGACTCTTTGGCGGAGCAGTTGGCGGTGCGGGGggaggtggtggtggtggtggtgcggCTGCCACACCCGGTGGCAAGTTCTACAGTCCGTTGCAGGTGGACACGAGTGGACTGAAGCCACAACAGTCGCCGCATCCGGCCCTCATGTACGGACTGAGTCAACGCTATCTGATGGAGATGTATGCGGCCAAGGCAACATCTCCGGCGGCGGCAGTGGCTCCGGATGTGCCGCAGTCCACGGTTGGTGGCACAGGTGGCACAGCGGTCACCGCAGCCAGTGGCAACTACAGCTGTGGCATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAACTCCACTCCCATCGCAAGTTGGCCCACAATCTGAAGACGGGAGTGAGTTTGAGATGCGCCTATTGCTCCGGCAACTTCAAGTCGCGGGCAGAGCTGGAGCAGCACATGAAGAGTTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTCCCCTCGCCGGCCATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAATCCGGCAAGTGTGCCCACTGTGGCCAGCAGCTGGAGCACGTCGCCGCCTTCCGGGCTCATCTCAGCGAGCATGGCGGCGATGGTAATCTGCCCATGGCCTGCATCTGTTGCCGCCAGACGCTGCACTCCGAGTTCGAGCTGAGTCTGCATGCCAAGTTCCACACCAAGTCACCAGGTGGCGCTGGTGGCAGCCTCCAGGAGCCGGTCTGTGCTCTGTGCCTGGAACCTTTACCGGGTGCCGGCGAAACTGCCAAGTTGTGTGAGAAATGTTGTCGCAAGCACAATCTCAATGGCAAGCGGAACAAGGAGCCGACTCCAGTGGCTGCAGCTGCTCCGGTTAATGCCGCCTCCGCCTACCTGGAGAATCGCTGCAATCTCTGCAAGATGATTTTACCGCATGCCCAGAAGCTGCAGGAGCATCTGGTGGAGCACACGTTTGCCGGCACCGAACAACGTGGATTCAATTGCTACATCTGCTCCGCCGTATTCACCGCCCCCGCCGGACTCCTCACCCACATTGCCGAGCACGGTGCTCGTCCCTATGACTGCAATCTGTGCCCCGAGAAGTTCTACTTCCGTGCCGAACTGGAGCATCATCAGCGTGCCCATGAGCTGAGACCGGCGCCTCCTGCAGCTGGACGCCTACCTCCCAAGCTGGAGACTCGCAGCTCCTCGGCCAGTTCCCCCCTCGCCCCGAGTCCGAGCCATGTCAAGCAGGAGCTCTATGAATCCGAGACGGCACCGTCACCCGCTGGCGAGGAGCCCTCCGgccaggaggaggaggagtacATCGAAGTGGAGCAGGTGCCGCATGAAACACGTTCCGGAGATCTCCTCAACTCCGCACACACCGAACGTTCCAGCAGCAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTLTPNSQHPHPHPHPHSQLSAAGEDPSSEQAKANGDTATAADEEREREREREREPAKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPTGAGTAGGAGGGGGGGGHGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRGRGQVATTPVSTPIPTPTPTPLLRCSYCPKVTEFSSLEQLNAHLQQAHEQARITTPGGDVETMQSNGFQLSCEYCTMRFVNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLSSPQQREQREQREHLMEKPEQELPTDLSSNKRRTVTPPTTVVATQAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLITSSEFNCSAGSCGKSFSKSDELQQHLNSEHVMTLLKCILCSELCESRMAMQLHLACAHSQETKLLRCSACMEIFRNDTDFHVHVKTRHQGGNGGGGVGVAGGVGGGAVSANPLQCMFCRAVCNSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKESPTKEPSSSPNMGSLYVNALLPPLAAAAAAAAVATNNNSNLHIDYNVAFKGLFGGAVGGAGGGGGGGGAAATPGGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAAVAPDVPQSTVGGTGGTAVTAASGNYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGGAGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKEPTPVAAAAPVNAASAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPAPPAAGRLPPKLETRSSSASSPLAPSPSHVKQELYESETAPSPAGEEPSGQEEEEYIEVEQVPHETRSGDLLNSAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: -
80% Identity: -