Basic Information

Insect: Drosophila acutilabella
Gene Symbol: L
Assembly: GCA_035046005.1
Location: JAWNOK010000008.1:814092-825458[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00088 19.8 2.9 1 23 172 194 172 194 0.98

2 17 0.39 30 5.5 6.2 1 23 200 222 200 222 0.97

3 17 1.9e-07 1.5e-05 25.4 3.2 1 23 228 250 228 250 0.99

4 17 1.4e-05 0.0011 19.5 0.4 1 23 256 278 256 278 0.99

5 17 0.056 4.4 8.2 0.2 2 23 355 379 354 379 0.91

6 17 0.0024 0.19 12.5 0.2 2 23 421 443 420 443 0.95

7 17 0.031 2.4 9.0 0.7 1 23 529 551 529 551 0.97

8 17 0.0057 0.45 11.3 0.1 2 23 559 580 558 580 0.91

9 17 0.00018 0.014 16.0 0.1 1 23 588 613 588 613 0.91

10 17 0.47 37 5.3 1.9 2 23 649 671 648 671 0.96

11 17 0.0028 0.22 12.3 1.1 1 23 723 746 723 746 0.97

12 17 0.0018 0.14 12.9 1.8 2 23 947 969 946 969 0.96

13 17 0.13 9.9 7.1 0.1 1 23 975 997 975 997 0.92

14 17 0.28 22 6.0 0.6 2 23 1005 1026 1004 1026 0.96

15 17 0.83 64 4.5 0.5 2 23 1127 1148 1127 1148 0.94

16 17 0.089 6.9 7.6 0.0 1 23 1158 1180 1158 1180 0.96

17 17 0.00025 0.019 15.6 1.2 1 23 1185 1207 1185 1207 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00088	19.8	2.9	1	23	172	194	172	194	0.98
2	17	0.39	30	5.5	6.2	1	23	200	222	200	222	0.97
3	17	1.9e-07	1.5e-05	25.4	3.2	1	23	228	250	228	250	0.99
4	17	1.4e-05	0.0011	19.5	0.4	1	23	256	278	256	278	0.99
5	17	0.056	4.4	8.2	0.2	2	23	355	379	354	379	0.91
6	17	0.0024	0.19	12.5	0.2	2	23	421	443	420	443	0.95
7	17	0.031	2.4	9.0	0.7	1	23	529	551	529	551	0.97
8	17	0.0057	0.45	11.3	0.1	2	23	559	580	558	580	0.91
9	17	0.00018	0.014	16.0	0.1	1	23	588	613	588	613	0.91
10	17	0.47	37	5.3	1.9	2	23	649	671	648	671	0.96
11	17	0.0028	0.22	12.3	1.1	1	23	723	746	723	746	0.97
12	17	0.0018	0.14	12.9	1.8	2	23	947	969	946	969	0.96
13	17	0.13	9.9	7.1	0.1	1	23	975	997	975	997	0.92
14	17	0.28	22	6.0	0.6	2	23	1005	1026	1004	1026	0.96
15	17	0.83	64	4.5	0.5	2	23	1127	1148	1127	1148	0.94
16	17	0.089	6.9	7.6	0.0	1	23	1158	1180	1158	1180	0.96
17	17	0.00025	0.019	15.6	1.2	1	23	1185	1207	1185	1207	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGCTTTATCGCGGTCCCAGCACGCGTTTAGAGAATTTAATTGAGAAGATTCAAGCCACAAAGGAGATTTCCAATAACGACATGTACAGCACACACACCTCCTCGAGCTACTCGCCCAGCATTTCGGATGGAACACTGACGCCCAACTCGCACCAGCCACATCCACATTCGCATCCACAACTCTTAGGTGCTGGAGAGGATCTGGGCAAGGCAAATGGGGATACAGTATCTCCTATCGATGAGgaacgagagagagaaagggagagggagcGGGAACGGGAGCCACCCAAATTAAAGCGCCCCTCCCACTtacatcatcattatcatcatcagcaaGCACTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAACTTGCAGGACCCACAGGGGCAGGAGGAGGCGGAGGCGGAGGCGGAGGACTTGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGTATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGCCTCGGTTACTTGAAGCATCACGTCCAGAGCCACGCCGAGCACTTGCCTTTCAAATGCGAATACTGCGCCAAATTATTCAAGCACAAACGCTCCCGAGATCGCCATAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCACACTGCGAGGCCGCTTTCTCCAGAAGTGACCACCTGAAGATCCACATGAAGACCCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATAGGGGCTACAACACGGCTGCGGCCCTGACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCAATACTGGCAGCAGGTGGCAATCCTAATGCGCTCAACTACAGTCCTCGCAGCACTGGATCCGCCTCCATCTCCAGCAACGGAAGTCTCCACAAACGACGCTACGCCCTGGCGCTTGCCTCCGACAGCAGCCCCAGTCGCCTTGAGTACCCCAAACGTGGTCGTACCCAAGTTACTGGCACgcccacacatacacctacGCCTACGCCGCTGCTGCGCTGCAGTTACTGTACCAAGGCGACGGAGTTTAGCAGCCTGGAGCAGCTGAATGCCCACTTGCAGCTGGCCCATGAGCAGCAGGCGAGGATTTCGACCAGTACCACTTCGGGTAGAGCAGCGAGTGGAGCAGCCGGAGGCGGAGTGGGAAGTGGAGGAGTGGGAGGAGATGTAGAGAGCCCGAATGGGTTCCAACTAAGCTGCGAGTACTGCACCATGCGGTTCGGCAATATTGCCGCTCTCTTCCAACACATGCGAGCCACGCATCTGGATCGTCTGAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGCCTCGCCACCACAGGCACTTTTAGTCCGCGTCTGGCCATGGAGCTGCCCAAAATCAAGCAGGATCTTGGCAGTCCACAGCGGGAGCGGGAGCGGGAGCGGGAACGTGAATTGGAGCTAGAGAAACCCGAGCAGGAGCTGCCGACAGATTTGAGCAGCAACAAGCGAAGGGGCACACCACCCCAACAACAAGGGCCGCCACCTGGCGTCTTCTTTTGTAACCAATGCAATGCGGGTCTGCCCGACTTCGAGAGCTTCCGGAATCACCTGAAGACGCACATAGCTGAGGGCATGCAGCTTATCTGTCCCCACTGCGGGCTCAGTCTGCCCGAACAGAGCGAGTTCGAGCGCCACGTGGTCGCCCATTTCCTGATCTCTGGCAGCGAGTACAACTGCAGTGCCAACAGCTGTGGTAAATCATTTGCCCAGTCGGAGGAACTGCAGCAGCATTTGAGTGGGGAGCACGTGGTCACTTTGCTTAAGTGCACGCTCTGCTCAGAGCTCTGTGAGACCAGGATGGCCATGCAGCTTCATTTGGCCTGCTCCCACAGCCAGGAGACGAAGCTGCTCCGTTGCAGCGCCTGCCTGGAGACCTTTCGGAGCGACACCGACTTTCATGTGCATGTCAAGACACGTCACCAGCTGCCGAGTACCCAAGGAGGGGCAGTTGGTGGTGGTCCGGTTCAAGCTCCTCCAGGAACTCCAGCCAATCCATTGCAGTGCATGTTCTGCCGCGTCGTGTGCTCCTCTGAACTGGAGATGCACTTCCATCTGGCAGCCCATGCGCGCCAGTTCCGTTGCCCCTCCTGTCCCGAGACCTTCCACGTAGAGTTCCTGTTGGACCGACACATGCAAAGCCAGCACGGCGGTCCCAAGGACGCCACCAATGGACCCAAGGAGCCTGCCAACAGCTCGTCCCCCAACATGGGCAGTCTCTATGTGAACGCACTGCTGCCTCCACTcgccgccgctgccgctgcagccgCCGCAGCTgccgccaacgccaacgccaacgccaccgccactaacaacaacagcagcctcCACATCGACTACAACGTGGCCTTTAAGGGGCTCTTCGGAGGTGCAGGCGGAGCGGTGGCTCCCACTGGAAAGTTCTACAGTCCGCTGCAAGTGGACACAAGTGGTTTGAAGCCACAACAGACGCCACATCCGCCTCCACATCCGCATCCACATCCGGCCCTGATGTACGGTCTGAGCCAGCGCTATCTGATGGAGATGTACGCGGCCAAGGCGACATCTCCGGCTGCAGCTTCTGCTCCTGATGTGCCtgtacagcagcagcagccgccgcagcagcagtCAACGGCAGGAGGAGGCACTGCGTCCAGTGGCGGTAACAGCTACAGCTGCGGCATGTGCGAGCGCCAGGATCTGAGAAGCGAGGCGGAACTACATTCGCACCGAAAGTTGGCCCACAACCTCAAGACGGGCGTGAGCCTGAGATGTGCTTACTGCTCGGGTAACTTCAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAAAGCTGCCACAACTCCAGTGGCAAACACAAATGTCTCATCTGCGACGAGATCTTTCCATCGCCAGCGATTCTCGCTGAGCATAAACTGCAGCACTCGAAGGTGGGGCAGTCCGGGAAGTGCGCCCACTGTGGCCAACAGCTGGAGCATGTGGCCGCCTTCCGGGCCCATCTTAGCGAGCATGGCGGTGATGGGAATCTACCCCTGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGCCTTCATGCTAAATTCCACACAAAGTCTCCCGGGGCAGGTGGTAGCCTCCAGGAACCCGTCTGTGCGCTGTGCCTAGAGCCTTTGCCCGGAGCTGGTGAGACGGCCAAGCTGTGCGAGAAATGTTGTCGCAAACATAACCTCAACGGGAAGCGGAACAAGGAACCCACTCCGTTGGGTGTACCAGCTCAAGCTCAAGCGCCGGCACCAGCAGGTAGCTACTTGGAGAACCGCTGCAATCTCTGCAAGATGATACTGCCGCATGCCCAGAAACTCCAGGAGCACCTTGTGGAACACACCTTTGCCGGAACCGAGCAGCGTGGCTTCAACTGTTACATCTGCTCCTCCGTGTTTACCGCACCCGCCGGTCTTCTAACCCACATTGCCGAGCACGGCGCTCGTCCCTACGATTGCAATCTCTGCCCCGAGAAGTTCTACTTTCGCGCAGAACTAGAGCACCATCAACGTGCACACGAGCTGAGACCCGCAAATCCTACACGCGTTGCCAAACAGGAGACCCGCAGTACCTCGGCCAGCTCTCCCATCGCTCTTAGTCCCAGTCATGTCAAGCAGGAGCTTTACGAGCCGGAGACACCCAACTCTCCTGCTGCCAACGCCACCACAGAGCACTCTGGCCCAGtacaggaggaggaggagtacATCGAAGTGGAGCAGGTTCCACACGATATTCGTTCTGGAGATCTTCTTTCCTCCGCACAAGCAGAGCGGTCCAGCAGCAGCGCTTAA
Protein Sequence: MMALKMLYRGPSTRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTLTPNSHQPHPHSHPQLLGAGEDLGKANGDTVSPIDEEREREREREREREPPKLKRPSHLHHHYHHQQALKIANKLRKINKEAKLAGPTGAGGGGGGGGGLGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEYPKRGRTQVTGTPTHTPTPTPLLRCSYCTKATEFSSLEQLNAHLQLAHEQQARISTSTTSGRAASGAAGGGVGSGGVGGDVESPNGFQLSCEYCTMRFGNIAALFQHMRATHLDRLSSPNSYYEHFNRLATTGTFSPRLAMELPKIKQDLGSPQRERERERERELELEKPEQELPTDLSSNKRRGTPPQQQGPPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISGSEYNCSANSCGKSFAQSEELQQHLSGEHVVTLLKCTLCSELCETRMAMQLHLACSHSQETKLLRCSACLETFRSDTDFHVHVKTRHQLPSTQGGAVGGGPVQAPPGTPANPLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGPKDATNGPKEPANSSSPNMGSLYVNALLPPLAAAAAAAAAAAANANANATATNNNSSLHIDYNVAFKGLFGGAGGAVAPTGKFYSPLQVDTSGLKPQQTPHPPPHPHPHPALMYGLSQRYLMEMYAAKATSPAAASAPDVPVQQQQPPQQQSTAGGGTASSGGNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGGDGNLPLACICCRQTLHSEFELSLHAKFHTKSPGAGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKEPTPLGVPAQAQAPAPAGSYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSSVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPANPTRVAKQETRSTSASSPIALSPSHVKQELYEPETPNSPAANATTEHSGPVQEEEEYIEVEQVPHDIRSGDLLSSAQAERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: iTF_00478915;
80% Identity: -