Basic Information

Insect: Drosophila kuntzei
Gene Symbol: L
Assembly: GCA_035042165.1
Location: JAWNLU010001854.1:7063860-7073496[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00081 19.9 2.9 1 23 171 193 171 193 0.98

2 17 0.37 28 5.6 6.2 1 23 199 221 199 221 0.97

3 17 1.8e-07 1.3e-05 25.5 3.2 1 23 227 249 227 249 0.99

4 17 1.3e-05 0.00099 19.6 0.4 1 23 255 277 255 277 0.99

5 17 0.025 1.8 9.3 0.2 2 23 358 382 357 382 0.90

6 17 0.0012 0.089 13.5 0.2 2 23 407 429 406 429 0.95

7 17 0.029 2.2 9.1 0.7 1 23 518 540 518 540 0.97

8 17 0.0082 0.61 10.8 0.1 2 23 548 569 547 569 0.91

9 17 6.5e-05 0.0048 17.4 0.2 1 23 577 602 577 602 0.93

10 17 4.6 3.4e+02 2.2 1.5 2 23 638 660 637 660 0.94

11 17 0.0027 0.2 12.3 1.1 1 23 706 729 706 729 0.97

12 17 0.0017 0.13 12.9 1.8 2 23 905 927 904 927 0.96

13 17 0.12 9.1 7.1 0.1 1 23 933 955 933 955 0.92

14 17 0.36 26 5.7 0.7 2 23 963 984 962 984 0.95

15 17 0.79 59 4.6 0.5 2 23 1082 1103 1082 1103 0.94

16 17 0.034 2.5 8.9 0.0 1 23 1113 1135 1113 1135 0.96

17 17 0.00024 0.018 15.7 1.2 1 23 1140 1162 1140 1162 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00081	19.9	2.9	1	23	171	193	171	193	0.98
2	17	0.37	28	5.6	6.2	1	23	199	221	199	221	0.97
3	17	1.8e-07	1.3e-05	25.5	3.2	1	23	227	249	227	249	0.99
4	17	1.3e-05	0.00099	19.6	0.4	1	23	255	277	255	277	0.99
5	17	0.025	1.8	9.3	0.2	2	23	358	382	357	382	0.90
6	17	0.0012	0.089	13.5	0.2	2	23	407	429	406	429	0.95
7	17	0.029	2.2	9.1	0.7	1	23	518	540	518	540	0.97
8	17	0.0082	0.61	10.8	0.1	2	23	548	569	547	569	0.91
9	17	6.5e-05	0.0048	17.4	0.2	1	23	577	602	577	602	0.93
10	17	4.6	3.4e+02	2.2	1.5	2	23	638	660	637	660	0.94
11	17	0.0027	0.2	12.3	1.1	1	23	706	729	706	729	0.97
12	17	0.0017	0.13	12.9	1.8	2	23	905	927	904	927	0.96
13	17	0.12	9.1	7.1	0.1	1	23	933	955	933	955	0.92
14	17	0.36	26	5.7	0.7	2	23	963	984	962	984	0.95
15	17	0.79	59	4.6	0.5	2	23	1082	1103	1082	1103	0.94
16	17	0.034	2.5	8.9	0.0	1	23	1113	1135	1113	1135	0.96
17	17	0.00024	0.018	15.7	1.2	1	23	1140	1162	1140	1162	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagattCAAGCCACAAAGGAGATTTCAAATAACGATATGTACAGCACGCACACCTCCTCCAGCTACTCGCCAAGCATCTCGGATGGCACATTGACGCCCAACTCGCAGCATCCGCATCCACAGCTCTCAGCTTCTGGCGAGGATCCTAGCTGTGAGCAGGCCAAGGCGAATGGGGACACGGCCACTGCTGCTGATGAGgagcgagagagggagagagatcgGGAGCCACCTAAGCTAAAGCGACCCGCTCAtttgcatcatcatcatcatcattatcatcatcagcaggCGTTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAACTCACAGGACCCACAGGAGGtggaggcggaggaggaggaggagcaggacaTGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAATGCGAATACTGCGCCAAATTATTCAAGCACAAACGTTCCCGAGATCGTCATAAGAAGCTCCATACCAACGAGAGGAACTACAAGTGTCCGCATTGTGAGGCCGCTTTCTCCAGAAGCGACCACTTGAAGATCCACATGAAGACGCACGATATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGGGGCTACAACACGGCGGCAGCATTGACCTCGCACATGCAGAAGCATAAGAAGAATGCGGCAATACTGGCAGCTGGTGGCAACCCTAATGCCCTTAACTATAGTCCACGTAGCACTGGCTCTGCCTCGATCTCCAGCAATGGGAGTCTCCACAAGCGACGCTATGCATTGGCACTCGCCTCCGACAGCAGTCCAAGTCGGATGGAGTATCCGAAACGGGGTCGTGGTCATGTGGCAACCACACCGATTCCAACACCGATCCCAACACCGATGCCGACTCCTTTGCTACGTTGCAGCTACTGTCCCAAGGTGACGGAGTTCAGCAGCCTGGAGCAATTGAACGCACATCTACAGCAGGCGCacgagcagcagcaggcgaGGATTACGACGCCTGGAGGCGATGCGGAGTCGATGCAGACGAATGGCTTCCAATTGAGCTGCGAGTACTGCACCATGAGATTCGTGAATATCGCCGGATTATTCCAACATATGCGTGCCACACACTTGGATCGCTTGAGCAGTCCCAACTCCTACTATGAGCACTTCAATCGTCTGGCCACCGCGGGCACATTTAGTCCACGTCTGGCAATGGAGCTGCCCAAGATTAAGCAGGATCTGGGCAGTCCACAGCAGCGGGATCAGGTCATGGAGAAGCCGGAACAGGAGCTGCCCACCGATCTGAGCAGCAATAAGCGACGCACTTTGACAccacccacaacaacaacaacaacagcaacagtagcagcaCCACAAGCGCCACCTGGCGTCTTCTTTTGCAATCAATGCAATGCAGGGTTGCCGGACTTTGAAAGTTTCCGTAATCATCTAAAGACACATATTGCCGAAGGAATGCAACTGATCTGTCCACACTGTGGATTAAGTCTGCCGGAGCAGAGTGAATATGAACGTCATGTGGTTGCCCACTTCCTGATCACCAGCTCCGAGTTCAATTGCAGCGCCGGCAGCTGCGGAAAATCGTTTGCCAAGTCGGATGAACTGCAGCAGCATCTGAATAGCGAGCATGTGATCACGCTGCTCAAGTGCATCCTCTGCTCGGAGCTGTGCGAGACCCGGATGGCCATGCAGCTCCATTTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGTTGCGTTGTAGCGCCTGCATGGAGATCTTTCGCAATGATACGGATTTCCATGTGCACGTCAAGACCAGGCATCAAGGTGGAACGGGATCAGGcgtgggagtgggagtggcaACTGTTCCTACTAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTTTGCAACTCGGAGCTGGAGATGCATTTCCATTTGGCGGCACATGCTCGACAATTCCGCTGCCCCTCCTGCCCCGAGACATTCCACGTAGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCATGGTGGAATCAAGGAATCCCCCGGCAAGGAACCCAGCAGTTCACCCAACATGGGCAGCCTGTATGTGAATGCATTGTTGCCACCACTtgcggcagctgcagcagctgctgctgtggccaccaacaacaacagcaaccttCACATTGATTACAACGTGGCATTCAAGGGACTCTTTGGAGGAGCGGGTGGCGGTGCATCTGGTGGTGGTGCTGCCACACCCAGTGGCAAGTTCTACAGTCCGTTGCAGGTGGACACGAGTGGATTGAAGCCACAACAGTCGCCACATCCGGCCCTCATGTACGGACTCAGTCAACGCTATCTGATGGAGATGTATGCGGCCAAGGCAGCATCTCCGGCGGCAGCAAGTGCTCCGGATGTGCCGCAGTCCACAGTGTCCACAGGTGCCTCCGCCGCATCCAGTGGCAACTACAGCTGTGGAATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAACTCCATTCCCATCGGAAGTTGGCCCACAATCTGAAGACGGGCGTCAGCTTGAGATGCGCCTACTGTTCGGGCAACTTCAAGTCGCGGGCAGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGCGATGAGATCTTCCCCTCGCCGGCCATTCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAATCCGGCAAGTGTGCCCATTGTGGACAGCAGCTGGAGCACGTGGCCGCCTTCCGGGCTCATCTCACCGAGCATGGCAGCGATGGTAACCTGCCCATGGCCTGCATCTGTTGCCGCCAGACGCTTCACTCGGAGTTCGAGCTGAGTCTCCATGCCAAGTTCCACACCAAGTCACCCAGTGGTGGTGGCAGCCTCCAGGAGCCGGTCTGTGCTCTGTGCCTGGAACCATTGCCGGGTGCCGGAGAAACGGCCAAGTTGTGTGAGAAATGTTGCCGCAAGCATAATCTCAATGGCAAGCGGAACAAGGAGCCGGCTCCAGTGGCTGCAGCTGCTCCAGGTAATGCTGCTGCCACCTACCTGGAGAATCGTTGCAATCTCTGCAAGATGATCTTGCCCCATGCCCAGAAACTACAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAACAGCGTGGATTCAATTGCTACATCTGCTCCGCCGTCTTCACCGCCCCCGCCGGACTCCTGACCCACATTGCCGAGCACGGTGCTCGTCCCTATGACTGCAATCTGTGTCCCGAGAAGTTCTACTTCCGCGCCGAACTGGAGCATCACCAACGTGCCCATGAGCTGAGACCGGCACCTCCTCCAGCTGGACGCATCCATCCCAAGCAGGAGACACGCAGCTCCTCGGCCAGTTCCCCGATTGCCCTGAGTCCAAGTCATGTCAAACAGGAGCTCTATGAATCCGAGACGGCACCTTCACCCGCCGCCGAGCCCTCAACCCAGGAGGATGAGGAGTACATTGAAGTGGAGCAGGTGCCACACGAAACACGTTCCGGAGATCTACTGAATTCCGCACATACTGAACGCTCCAGCAGCAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTLTPNSQHPHPQLSASGEDPSCEQAKANGDTATAADEERERERDREPPKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPTGGGGGGGGGAGHGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRGRGHVATTPIPTPIPTPMPTPLLRCSYCPKVTEFSSLEQLNAHLQQAHEQQQARITTPGGDAESMQTNGFQLSCEYCTMRFVNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLAMELPKIKQDLGSPQQRDQVMEKPEQELPTDLSSNKRRTLTPPTTTTTTATVAAPQAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLITSSEFNCSAGSCGKSFAKSDELQQHLNSEHVITLLKCILCSELCETRMAMQLHLACAHSQETKLLRCSACMEIFRNDTDFHVHVKTRHQGGTGSGVGVGVATVPTNPLQCMFCRAVCNSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKESPGKEPSSSPNMGSLYVNALLPPLAAAAAAAAVATNNNSNLHIDYNVAFKGLFGGAGGGASGGGAATPSGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKAASPAAASAPDVPQSTVSTGASAASSGNYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLTEHGSDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSGGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKEPAPVAAAAPGNAAATYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPAPPPAGRIHPKQETRSSSASSPIALSPSHVKQELYESETAPSPAAEPSTQEDEEYIEVEQVPHETRSGDLLNSAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: -
80% Identity: -