Dimm000691.1
Basic Information
- Insect
- Drosophila immigrans
- Gene Symbol
- L
- Assembly
- GCA_963583835.1
- Location
- OY757141.1:4741653-4750850[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.1e-05 0.00074 19.8 2.9 1 23 178 200 178 200 0.98 2 17 0.38 25 5.5 6.2 1 23 206 228 206 228 0.97 3 17 1.9e-07 1.2e-05 25.4 3.2 1 23 234 256 234 256 0.99 4 17 1.4e-05 0.0009 19.5 0.4 1 23 262 284 262 284 0.99 5 17 0.47 31 5.3 0.1 2 23 370 394 369 394 0.85 6 17 0.087 5.7 7.6 0.3 2 23 421 443 420 443 0.94 7 17 0.03 2 9.0 0.7 1 23 526 548 526 548 0.97 8 17 0.0057 0.37 11.3 0.1 2 23 556 577 555 577 0.91 9 17 0.00011 0.0074 16.7 0.1 1 23 585 610 585 610 0.91 10 17 5.6 3.7e+02 1.9 1.6 2 23 646 668 645 668 0.95 11 17 0.0028 0.18 12.3 1.1 1 23 722 745 722 745 0.97 12 17 0.0018 0.12 12.9 1.8 2 23 929 951 928 951 0.96 13 17 0.13 8.3 7.1 0.1 1 23 957 979 957 979 0.92 14 17 1.5 1e+02 3.7 1.2 2 23 987 1008 986 1008 0.93 15 17 0.81 53 4.5 0.5 2 23 1111 1132 1111 1132 0.94 16 17 0.034 2.3 8.8 0.0 1 23 1142 1164 1142 1164 0.96 17 17 0.00024 0.016 15.6 1.2 1 23 1169 1191 1169 1191 0.97
Sequence Information
- Coding Sequence
- ATGATGGccttaaaaatgttatatcGCGGTCCCAGTTCGCGTTTGGAGAATTTAATTGAGAAGATTCAAGCAACGAAGGAGGTTTCCAATAACGACATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCGGACGGCACTTTGACGCCCAACTCCCAGCAGCCGCATCCGCAGCTGTTGGCGGCTGGCGAGGATCCGGGCTCCGAGCCGTCCAAGGCGAATGGCGACGCCTCGACTGCAGCCGACGAGGACCGAGAGGGTCAAAGGGAGCGGGAACGGGATCCACCCAAGCTGAAGCGACCCGCCCACTtgcatcatcaccatcatcattatcatcatcagcaggcGCTGAAAATTGCCAACAAGTTGCGTAAAATCAATAAGGAAGCAAAGCTCACAGGACCCGCAGCAGGAggcggagcaggagcaggaggtgGAGGCGGAGGTGGCAACACTGGCGCAGCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGCGACAAATCATTTCCACGACTCGGCTACTTGAAGCATCACGTCCAGAGCCACGCCGAACATTTGCCTTTCAAATGCGAGTACTGCGCCAAGTTATTCAAGCACAAGCGCTCCCGCGATCGCCACAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCGCACTGCGAAGCCGCTTTCTCCAGGAGCGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACCGCCGCCGCGCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCCATCCTGGCGGCCGGCGGCAACCCCAACGCCCTCAACTACAGTCCGCGCAGCACGggctccgcctccgcctccgcctcgctctccagccacagcaacggcagTCTGCACAAGCGGCGCTATGCGCTGGCGCTCGCCTCCGACAGCAGCCCAAGTCGCCTCGAGTATCCGAAGCGCAGTCGAGGGCACCACGTGCCCACCACACCCACGCCCACAGGCACGCCCATGGGCACGCCGCTGCTGCGCTGCAGCTACTGCCCCAAGGCGGTCGAGTTTGGCAGCCTGGAGCAGCTGAATGCGCATCTGCAGCAGGCGCACGACCAGAAGGCGCCAGACGGACAGCCTGAAGCGGGCGAGGATGGCAAGGGGCAGGGACAGGCGAATGGCTTCCAACTGAGCTGCGAGTACTGCACGATGCGGTTCCTGAACATTGCCGGCCTGTTCCAGCACATGCGCGCCACGCACCTGGACCGGCTGAGCAGTCCCAACTCCTACTACGAGCACTTCAACCGCCTGGCCACGGCGGGCACGTTCAGTCCGCGCCTGGCGCTGGAGCTGCCCAAGATCAAGCCGGATCTGGGCAGTCCGCCGCTGCCGAAGCCGGAGCAGGAGCTGCCCACGGACCtaagcagcaacaaacggCGCACGGTGACGCCaccaggaggaggaggagcaatCGCTGCCGCACcagcgccgccgccaccgGGCGTCTTCTTCTGCAACCAGTGCAACGCGGGGCTGCCGGACTTCGAGAGCTTCCGGAACCATCTGAAGACGCACATTGCCGAGGGCATGCAGCTGATCTGTCCGCACTGCGGCCTCAGTCTGCCCGAGCAGAGCGAGTTCGAGCGCCACGTGGTCGCCCACTTCCTCATCGCCGGCTGCGAGTTCAACTGCGGCGCCGCCAGCTGCGGCAAGTCGTTTGCCAAGTCGgacgagctgcagcagcacctCAACAGCGAGCACGTGGTCACCCTGCTGAAGTGCGCGCTCTGCGCCGAGATCTGCGAGACGCGGATGGCGATGCAGCTGCATCTGGCCTGTGCCCACGGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCTTGGAGCTCTTCCGCAACGACACCGACTTCCATGTGCACGTGAAGACGCGCCATCAGCTGGCCAGCGGCCACCAGGCTCCACCGCCGCCCACAGCCCCGCCAGGCCACGGACACGGTCAGGGACAGGCGAATCCCCTGCAGTGCATGTTCTGCCGCGCCGTCTGCTCCTCGGAGCTGGAGATGCACTTCCACCTGGCGGCGCACGCCCGCCAGTTCCGCTGCCCCTCGTGTCCCGAGACCTTCCACGTCGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCGTCAAGGAGCGCAGTCCCGTCAAGGAGACCTCGCCCAGCATGGGCAGCCTCTACGTGAACGCCCTGCTGCCGCCcctggcagctgctgcggccgccgccgccgccgccgcgaccaacaacaacagcagcctcCACATCGACTACAACGTGGCCTTCAAGGGCCTCTTCGGTGGGGCTGGCGCTCCCGCCGGAGCCGCTgcgggcggcggcggcaagtTCTACAGCCCGCTGCAGGTGGACACGAGCGGCCTGAAGCCGCAGCAGTCGCCGCACCCCGCGCTGATGTACGGCCTCAGCCAGCGCTACCTCATGGAGATGTACGCCGCCAAGGCGACCTCCCCGGCGGCAGCCAGCGCCCCCGAAGTACCCGtccagcctcagcctcagtcgcaatcgcaatcgcagacAGCCGGTTCGGGCAATTCGGGAGTGACGAGCGGCAGCTACAGCTGCGGGATGTGCGAGCGGCAGGATCTGCGCAGCGAGGCGGAGCTGCATTCGCACCGCAAGCTGGCGCACAACCTGAAGACGGGAGTGAGCCTGCGGTGCGCCTACTGCTCGGGCAACTTCAAGTCGCGGGCggagctggagcagcacaTGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATTCTCGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCGCCCACTGCGGCCACCAGCTGGAGCACGTGGCCGCCTTTCGCGCCCACCTCGGCGAGCATGGCGGCGACGGCAACCTGCCCATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCCGAGTTCGAGCTCAGCCTGCACGCCAAGTTCCACACGAAGTCcgccggcggcggcggcgccagTCTTCTGGAGCCGGTCTGCGCCCTCTGCCTGGAGCCACTGCCCGGGGCCGGAGACACCGCCAAGCTGTGCGACAAGTGCTGTCGCAAGCACAACCTCAATctcaatggcaacggcaacggcaagcGGAGCAAGGAGTCTGCTGCGGCTTCTGCGCCCCCTCCAGTCCCCTCCAGCTACCTGGAGAACCGCTGCAACCTCTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAGGAGCACCTCGTGGAGCACACGTTCGCCGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCGGTCTTCACCGCACCCGCGGGCCTTCTCACCCACATCGCCGAGCACGGTGCTCGACCCTACGACTGCAACCTCTGTCCCGAGAAGTTCTACTTCCGCGCCGAGCTGGAGCACCATCAGCGTGCCCACGAGCTGAGGCCAGCTCctgttccagttccagttcctgCTCCGCCAGCGGCTCGCGTGCCCAAGCAGGAGGCCCGCAGTTCCTCGGCCTCAGCGTCAGCTTCGGCGAGTTCGCCCCTCGCCCTCAGTCCGAGTCACGTCAAGCAGGAGCTGTACGATGCCGAGACGGCTCCCTCGCCCCCCGCCACGGAGGCGCCCGTCCAGGACGACGAGGAGTACATCGAGGTGGAGCAGATGCCGCTCGAGACCCGCTCCGGAGATCTGTTGGCTGCCTCGCACACCGAAcgctccagcagcagcgcctAA
- Protein Sequence
- MMALKMLYRGPSSRLENLIEKIQATKEVSNNDMYSTHTSSSYSPSISDGTLTPNSQQPHPQLLAAGEDPGSEPSKANGDASTAADEDREGQRERERDPPKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPAAGGGAGAGGGGGGGNTGAAAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASASLSSHSNGSLHKRRYALALASDSSPSRLEYPKRSRGHHVPTTPTPTGTPMGTPLLRCSYCPKAVEFGSLEQLNAHLQQAHDQKAPDGQPEAGEDGKGQGQANGFQLSCEYCTMRFLNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPPLPKPEQELPTDLSSNKRRTVTPPGGGGAIAAAPAPPPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLIAGCEFNCGAASCGKSFAKSDELQQHLNSEHVVTLLKCALCAEICETRMAMQLHLACAHGQETKLLRCSACLELFRNDTDFHVHVKTRHQLASGHQAPPPPTAPPGHGHGQGQANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKERSPVKETSPSMGSLYVNALLPPLAAAAAAAAAAATNNNSSLHIDYNVAFKGLFGGAGAPAGAAAGGGGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAASAPEVPVQPQPQSQSQSQTAGSGNSGVTSGSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLGEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSAGGGGASLLEPVCALCLEPLPGAGDTAKLCDKCCRKHNLNLNGNGNGKRSKESAAASAPPPVPSSYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPAPVPVPVPAPPAARVPKQEARSSSASASASASSPLALSPSHVKQELYDAETAPSPPATEAPVQDDEEYIEVEQMPLETRSGDLLAASHTERSSSSA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00507081;
- 90% Identity
- -
- 80% Identity
- -