Basic Information

Insect: Drosophila quinaria
Gene Symbol: L
Assembly: GCA_035047525.1
Location: JAWNPO010000268.1:3466919-3475156[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.2e-05 0.00098 19.8 2.9 1 23 188 210 188 210 0.98

2 17 0.42 34 5.5 6.2 1 23 216 238 216 238 0.97

3 17 2e-07 1.6e-05 25.4 3.2 1 23 244 266 244 266 0.99

4 17 1.5e-05 0.0012 19.5 0.4 1 23 272 294 272 294 0.99

5 17 0.19 15 6.6 0.2 2 23 381 405 380 405 0.87

6 17 0.00046 0.037 14.9 0.6 2 23 430 452 429 452 0.96

7 17 0.033 2.6 9.0 0.7 1 23 536 558 536 558 0.97

8 17 0.0062 0.49 11.3 0.1 2 23 566 587 565 587 0.91

9 17 7.3e-05 0.0058 17.4 0.2 1 23 595 620 595 620 0.94

10 17 5.1 4.1e+02 2.1 1.5 2 23 656 678 655 678 0.94

11 17 0.0031 0.24 12.3 1.1 1 23 730 753 730 753 0.97

12 17 0.002 0.16 12.9 1.8 2 23 951 973 950 973 0.96

13 17 0.14 11 7.1 0.1 1 23 979 1001 979 1001 0.92

14 17 0.4 32 5.6 0.7 2 23 1009 1030 1008 1030 0.95

15 17 0.89 71 4.5 0.5 2 23 1131 1152 1131 1152 0.94

16 17 0.031 2.4 9.1 0.0 1 23 1162 1184 1162 1184 0.96

17 17 0.0099 0.79 10.7 1.2 1 23 1189 1211 1189 1211 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.2e-05	0.00098	19.8	2.9	1	23	188	210	188	210	0.98
2	17	0.42	34	5.5	6.2	1	23	216	238	216	238	0.97
3	17	2e-07	1.6e-05	25.4	3.2	1	23	244	266	244	266	0.99
4	17	1.5e-05	0.0012	19.5	0.4	1	23	272	294	272	294	0.99
5	17	0.19	15	6.6	0.2	2	23	381	405	380	405	0.87
6	17	0.00046	0.037	14.9	0.6	2	23	430	452	429	452	0.96
7	17	0.033	2.6	9.0	0.7	1	23	536	558	536	558	0.97
8	17	0.0062	0.49	11.3	0.1	2	23	566	587	565	587	0.91
9	17	7.3e-05	0.0058	17.4	0.2	1	23	595	620	595	620	0.94
10	17	5.1	4.1e+02	2.1	1.5	2	23	656	678	655	678	0.94
11	17	0.0031	0.24	12.3	1.1	1	23	730	753	730	753	0.97
12	17	0.002	0.16	12.9	1.8	2	23	951	973	950	973	0.96
13	17	0.14	11	7.1	0.1	1	23	979	1001	979	1001	0.92
14	17	0.4	32	5.6	0.7	2	23	1009	1030	1008	1030	0.95
15	17	0.89	71	4.5	0.5	2	23	1131	1152	1131	1152	0.94
16	17	0.031	2.4	9.1	0.0	1	23	1162	1184	1162	1184	0.96
17	17	0.0099	0.79	10.7	1.2	1	23	1189	1211	1189	1211	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTAATAGAAAAGATTCAAGCTACAAAGGAGATTTCCAATAGCGATATGTACAGCACGCACACCTCCTCCAGCTACTCGCCGAGCATCTCGGATGGCACCATGACGCCCAACTCAACGCAGCATCCACATTCACAGCTCACAGTTTCTGGCGAGGATGCGAGCTCGGAGCAGGCCAAGGCCAATGGAGAtgcaggagcaggaggaacTGCAGCTGATgaagagcgagagcgagagagggagagggacagAGAAAGGACAGAGAGGGAGCCATTGAAGCTAAAGCGACCCGCTCTtttgcatcatcatcatcatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAACTCGCAGGTCccacaggagcaggagcaggcggaggaggaggaggcggaacTGGAGGCGGGGCAGGACATGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGAGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGTTGTTCAAGCACAAGCGTTCCCGAGACCGTCATAAGAAGCTCCACACCAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCCGCTTTCTCCAGAAGCGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGGGGCTACAACACGGCAGCCGCCCTGACTTCGCACATGCAGAAGCACAAGAAGAACGCGGCAATACTGGCCGCTGGTGGCAACCCTAATGCCCTCAACTACAGTCCCCGCAGCACGGGTTCGGCCTCGATATCGAGCAACGGGAGTCTGCACAAGCGACGTTATGCTCTGGCCCTCGCCTCCGACAGCAGCCCGAGTCGCATGGAGTATCCGAAGCGGGCACGCGGCCAGGTGGCAACCCAGCCGACGCCCACAGCGACACCGACTCCGAACCCGAACCAGACGCCGACTCCCACTCCTCTGCTGCGCTGCAGCTACTGTCCCAAGGTGACGGAGTTCAGCAGCTTGGAGCAGTTGAACGGGCATCTGCAGCAGGCGcacgagcagcagcaggcgaGGATCACGACACCTGGCGGCGATCAGGAGACGATGCCGGCGAATGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGCGATTCAACAATATTGCCGGACTGTTCCAGCACATGCGCTCCACGCACTTGGATCGGCTGAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCGGGCACCTTTAGTCCGCGTCTGGCACTGGAGCTGCCCAAGATCAAGCCGGATCTGGGCAGTCCACAGCGGGAGCAGGTGATGGAGAAGATGGAGCAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGCACATTGACGCCACCTACGACTATTGTGGCACCTCCAGCTGCAGCGCCACCTGGCGTCTTCTTTTGCAATCAATGCAACGCAGGGTTGCCGGACTTTGAAAGCTTTCGCAATCACTTGAAAACCCACATCGCAGAGGGAATGCAACTGATCTGTCCCCATTGTGGCCTGAGTCTGCCGGAGCAGAGTGAATTCGAGCGCCATGTGGTTGCCCACTTCCTGATCAGCGGCTGTGAGTTCAACTGCAGTGCCGCCAACTGTGGCAAGTCCTTTGCCAAGTCGGAGGAACTGCAGCAGCATCTGAGCAGCGAGCATGTGATGCAGCTGCTCAAGTGCATCATCTGCTCGGAGCTGTGCGAGACGCGGATGGCCATGCAGCTCCACTTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCATGGAGATCTTTCGCACGGACACGGACTTCCATGTGCATGTCAAGACCAGACATCAGGGTGGCgcgggagtgggagtgggatcGGGAGTGGGTTCGGGCGTTCTGCCGCCTCCTGCGCCTGCGAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTGTGCAACTCGGAGCTGGAGATGCACTTCCACTTGGCGGCGCATGCGCGACAATTCCGCTGCCCCTCCTGCCCCGAGACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCATGGCGGCGTGAAGGATTGCCAGGCTAAGGAGCCCAGCGGTTCACCCAACATGGGCAGCCTATATGTGAATGCGTTGCTGCCACCATTGGCGgcagctgccgccgctgctgcggTGGCGACATCgacccacaacaacaacaacaacaacaacagcaatctgCACATTGACTACAATGTGGCATTCAAGGGTCTCTTCGGAGGAGCAGCTGGTGGAGTAGGAGGAGGCGGAGCTGCTGCCACAGGCGGTGGCAAGTTCTACAGTCCGCTGCAGGTGGACACGAGTGGCCTGAAGCCACAGCAGTCGCCACATCCGGCGCTGATGTACGGCCTGAGTCAGCGCTACCTGATGGAGATGTATGCGGCCAAGGCGACATCTCCGGCGGCGGTGACAAGTGCTCCGGATGTGACCCAATCATCATCGGGTGGcgctggagttggagctggagcagcGGGCAACGCCTCAAGtggaggaggcggaggcggcagcaacagctacaGTTGTGGCATGTGCGAGCGGCAGGATCTGCGCAGCGAGGCGGAACTCCACTCGCATCGCAAGCTGGCCCACAATCTGAAGACTGGCGTCAGTTTGAGATGCGCCTATTGCTCCGGCAACTTCAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTCCCCTCGCCCGCTATTCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCGGGCAAGTGCGCCCACTGTGGACAGCAGCTGGAGCACGTGGCCGCCTTTCGGGCCCATCTCACGGAGCATGGCGGCGATGGGAGTCTGCCCATGGCCTGCATCTGTTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGCCTGCACGCCAAGTTCCACACCAAGTCGCCAGGTGGCGCTGCGGGTGGCAGCCTCCAGGAGCCCGTCTGTGCCCTGTGCCTGGAGCCGTTGCCGGGTGCGGGAGACACCGCCAAGTTGTGTGAGAAATGTTGTCGCAAGCATAATCTCAATGGAAAGCGGCAGAAGGAAGccgctccagctccagctcctggTCCGAATAATGCTGCCTCCTCCAACTACCTGGAGAATCGCTGCAATCTCTGCAAGATGATACTGCCACACGCCCAGAAGCTGCAGGAGCATCTCGTGGAGCACACGTTCGCCGGCACCGAGCAGCGCGGATTCAATTGCTACATCTGCTCGGCCGTCTTCACCGCACCCGCTGGACTCCTCGCCCACATTGCCGAGCACGGCGCACGGCCCTACGACTGCAATCTGTGCCCCGACAAGTTCTACTTTCGCGCCGAACTGGAGCATCATCAGCGTGCCCATGAGCTGAGACCGTCAGCTCCTCCTCCTGTGCGTATCCCGCCCAAGCAGGAGAGGCGCAGCTCCCCGGCCAGCTCACCCCTTGCCCCGAGTCCGAGCCATGTCAAGCAGGAGCTCTATGAATCCGAGACGGCGCCTTCGCCCGCCGAAGTTGAGCCCTCAGCCCAAGAGGAGGAAGAGTACATTGAAGTGGAGCAGGTACCGCATGAAACACGGTCCGGAGACCTCCTAAATTCCGCACATACCGAACGCTCCAGCAGCAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEISNSDMYSTHTSSSYSPSISDGTMTPNSTQHPHSQLTVSGEDASSEQAKANGDAGAGGTAADEERERERERDRERTEREPLKLKRPALLHHHHHHYHHQQALKIANKLRKINKEAKLAGPTGAGAGGGGGGGTGGGAGHGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRARGQVATQPTPTATPTPNPNQTPTPTPLLRCSYCPKVTEFSSLEQLNGHLQQAHEQQQARITTPGGDQETMPANGFQLSCEYCTMRFNNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPQREQVMEKMEQELPTDLSSNKRRTLTPPTTIVAPPAAAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISGCEFNCSAANCGKSFAKSEELQQHLSSEHVMQLLKCIICSELCETRMAMQLHLACAHSQETKLLRCSACMEIFRTDTDFHVHVKTRHQGGAGVGVGSGVGSGVLPPPAPANPLQCMFCRAVCNSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDCQAKEPSGSPNMGSLYVNALLPPLAAAAAAAAVATSTHNNNNNNNSNLHIDYNVAFKGLFGGAAGGVGGGGAAATGGGKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAVTSAPDVTQSSSGGAGVGAGAAGNASSGGGGGGSNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLTEHGGDGSLPMACICCRQTLHSEFELSLHAKFHTKSPGGAAGGSLQEPVCALCLEPLPGAGDTAKLCEKCCRKHNLNGKRQKEAAPAPAPGPNNAASSNYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLAHIAEHGARPYDCNLCPDKFYFRAELEHHQRAHELRPSAPPPVRIPPKQERRSSPASSPLAPSPSHVKQELYESETAPSPAEVEPSAQEEEEYIEVEQVPHETRSGDLLNSAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: -
80% Identity: -