Drel006192.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila rellima
Gene Symbol
L
Assembly
GCA_035043635.1
Location
JAWNMV010000236.1:3134461-3143413[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1e-05 0.00076 19.8 2.9 1 23 181 203 181 203 0.98
2 17 0.37 26 5.6 6.2 1 23 209 231 209 231 0.97
3 17 1.8e-07 1.3e-05 25.4 3.2 1 23 237 259 237 259 0.99
4 17 1.3e-05 0.00093 19.6 0.4 1 23 265 287 265 287 0.99
5 17 0.17 12 6.7 0.2 2 23 375 399 374 399 0.87
6 17 0.00018 0.013 16.0 0.6 2 23 433 455 432 455 0.96
7 17 0.029 2 9.0 0.7 1 23 533 555 533 555 0.97
8 17 0.014 0.98 10.1 0.1 2 23 563 584 562 584 0.91
9 17 3.8e-05 0.0027 18.1 0.1 1 23 592 617 592 617 0.94
10 17 1.2 81 4.0 1.3 2 23 653 675 652 675 0.95
11 17 0.0027 0.19 12.3 1.1 1 23 722 745 722 745 0.97
12 17 0.0017 0.12 12.9 1.8 2 23 926 948 925 948 0.96
13 17 0.12 8.5 7.1 0.1 1 23 954 976 954 976 0.92
14 17 0.36 25 5.6 0.7 2 23 984 1005 983 1005 0.95
15 17 0.79 55 4.5 0.5 2 23 1105 1126 1105 1126 0.94
16 17 0.027 1.9 9.1 0.0 1 23 1136 1158 1136 1158 0.96
17 17 0.00024 0.016 15.6 1.2 1 23 1163 1185 1163 1185 0.97

Sequence Information

Coding Sequence
ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGCTTGgagaatttaattgaaaagattCAAGCCACCAAGGAGATTTCAAATAGCGACATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCGGACGGCACAATGACGCCCAACTCAACGCAGCAGCCGCATCCACAGCTCACAGCCTCTGGCGAGGATCCTAGCGCTGAGCAGGCCAAGACAAATGGGGAGACGGGCGGAACTGCAGCTGAcgaagagcgagagagagagagggagagggataGGGAGAGAGTAAGGGAGCCATTGAAGCTAAAGCGACCCGCTCATTtgcatcaccatcatcatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAACTCACAGGACCCCCAGGCGGAGGTGGAGGAAACGGAGctggaggtggaggaggacATGGAGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAATGCGAATACTGCGCCAAGTTATTCAAGCACAAACGCTCCCGAGATCGCCATAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCGCACTGCGAGGCCGCTTTCTCCAGAAGCGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGGGGCTACAACACGGCGGCCGCGTTGACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCAATACTGGCCGCTGGTGGCAACCCTAATGCACTGAACTACAGTCCACGCAGCACCGGCTCGGCCTCCATCTCGAGCAACGGGAGTCTGCACAAGCGACGCTATGCGCTGGCACTCGCCTCCGACAGCAGCCCCAGTCGGATGGAGTATCCGAAGCGGGCACGCGGCCAGGTGGCAACCCAGTCAACGACCCCGAACCCAAACCCGATCCCGACACcgactcaaactcaaactccaACTCCGTTGCTGCGCTGCAGCTACTGTCCCAAGGTGACGGAGTTCAGCAGCCTGGAGCAGTTGAACGGACATCTGCAGCAGGCgcacgagcagcagcagcagcagcagcagctggcgaGGATCACGACACCGGGACATGGACAGGCAGCAGATGGGGAGACGTTGCAGTCGAATGGCTTCCAGCTGAGCTGCGAGTACTGCACGATGAGATTCAGCAATATCGCCGGACTGTTCCAGCACATGCGCTCCACACACTTGGATCGTCTGAGCAGTCCCAACTCCTACTACGAGCACTTTAATCGTCTGGCCACCGCGGGCACCTTCAGTCCGCGTCTGGCCCTGGAGCTGCCCAAGATCAAGCCGGATTTGGGCAGTCCGCAGAGGGAGAAGCCGGAACAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGCACGCTGACGCCAcctgcagttgcagcagcgcATGCAGCGCCACCTGGCGTCTTCTTTTGCAATCAATGCAACGCAGGGTTGCCGGACTTTGAAAGCTTTCGCAATCACTTGAAGACGCACATTGCCGAAGGCATGCAACTGATCTGTCCACATTGCGGTCTCAATCTGAACGAGCAGAGTGAATTTGAGCGCCATGTGGTTGCCCATTTCCTGATCAGCAGCTGTGAGTTCAGCTGCAGTGCATCCGGCTGTGGCAAATCCTTTGCCAAGTCCgaggagctgcagcagcaTTTGAACGGGGAGCATGTGATGCAGCTGCTCAAGTGCGTCATCTGCTCGGAGCTGTGCGAGACGCGGATGGCGATGCAGCTCCATTTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGATCTTTCGCAGCGATACGGACTTCCATGTGCATGTCAAGACCCGGCATCAAAATGGAGccggagtgggagtgggagtggttACCGCTCCTGGTCCCGCTCCCAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTCTGCAACTCGGAGCTGGAGATGCACTTCCATTTGGCGGCACATGCGCGACAATTCCGCTGTCCCTCCTGCCCCGAAACGTTCCACGTGGAGTTTCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCGTCAAGGAATCGCCGGTGAAGGAGCCCAGCAGTTCACCCAACATGGGCAGTCTGTATGTGAATGCGTTGCTTCCTCCTTTGGCCGCAGCggccgcagctgctgcagtggcgtcgtccaacaacaacaacaacaacagcaatctgCACATTGACTACAATGTGGCATTCAAGGGTCTCTTTGGAGGAGCAGCTGGTGCcggaggagcagcagctgccacaggcGGCGGCAAGTTCTACAGTCCGCTGCAGGTGGACACGAGCGGACTGAAGCCGCAGCAGACGCCGCATCCGGCATTGATGTACGGACTCGGCCAGCGCTATCTGATGGAAATGTACGCGGCCAAGGCGACATCTCCGGCGGCGGCCAGTGCGCCCGATCCCGTGGCCCAGTCTGCCGGcggagcagctggagcagcggGCAGCGGGAGCGGCAGCTTCAGCTGTGGCATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAGCTCCATTCGCATCGGAAGCTGGCGCACAATCTGAAGACGGGCGTCAGCCTGAGATGCGCCTATTGCTCCGGCAACTTCAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGCGATGAGATCTTCCCCTCGCCCGCCATTCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGTGCCCACTGTGGCCAGCAGCTGGAGCACGTGGCCGCCTTTCGGGCCCATCTCACCGAGCATGGCGGCGATGGGAATCTGCCCATGGCCTGCATCTGTTGCCGCCAGACGTTGCACTCGGAGTTCGAGCTCAGTCTGCATGCCAAGTTCCATACCAAGTCGCCAGGTGGCGCTGCCAGTGGCAGCCTCCAGGAGCCGGTCTGCGCCCTCTGCCTGGAGCCGTTGCCGGGCGCCGGCGACACCGCCAAGTTGTGTGAGAAATGTTGCCGCAAGCACAATCTGAATGGCAAGCGGAACAAGGAGTccgcttcagtttcagctccagctccagctcctggTAATGCTGCCTACCTGGAGAATCGCTGCAATCTCTGCAAGATGATTCTGCCACATGCCCAGAAACTGCAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAGCAGCGTGGGTTCAACTGCTACATCTGCTCCGCCGTCTTCACCGCACCCGCCGGACTCCTCGCCCACATTGCCGAGCACGGTGCTCGGCCCTATGACTGCAATCTGTGCCCCGAGAAGTTCTACTTTCGCGCCGAGCTGGAGCATCATCAGCGTGCCCACGAGCTGAGACCGACACCGCCCGCTCCGGCGGTGCGCATTCCGCCCAAGCGCGAGAGACGCAGCTCCCCGGCCAGTTCGCCCTTGGCCCTGAGTCCGTGTCATGTCAAGCTGGAGCTGTATGAATCCGAGACGGCGCCGTCACCCGCCGCCGTCGAGTCCTCGGCaccggaggaggaggagtacATTGAGGTGGAGCAGGTGCCGCATGAAACGCGTTCCGGCGAACTCCTGAATTCCGGACACACCGAACgctccagcagcagcgccTAA
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEISNSDMYSTHTSSSYSPSISDGTMTPNSTQQPHPQLTASGEDPSAEQAKTNGETGGTAADEERERERERDRERVREPLKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPPGGGGGNGAGGGGGHGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRARGQVATQSTTPNPNPIPTPTQTQTPTPLLRCSYCPKVTEFSSLEQLNGHLQQAHEQQQQQQQLARITTPGHGQAADGETLQSNGFQLSCEYCTMRFSNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPQREKPEQELPTDLSSNKRRTLTPPAVAAAHAAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLNLNEQSEFERHVVAHFLISSCEFSCSASGCGKSFAKSEELQQHLNGEHVMQLLKCVICSELCETRMAMQLHLACAHSQETKLLRCSACLEIFRSDTDFHVHVKTRHQNGAGVGVGVVTAPGPAPNPLQCMFCRAVCNSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKESPVKEPSSSPNMGSLYVNALLPPLAAAAAAAAVASSNNNNNNSNLHIDYNVAFKGLFGGAAGAGGAAAATGGGKFYSPLQVDTSGLKPQQTPHPALMYGLGQRYLMEMYAAKATSPAAASAPDPVAQSAGGAAGAAGSGSGSFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLTEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGGAASGSLQEPVCALCLEPLPGAGDTAKLCEKCCRKHNLNGKRNKESASVSAPAPAPGNAAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLAHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPTPPAPAVRIPPKRERRSSPASSPLALSPCHVKLELYESETAPSPAAVESSAPEEEEYIEVEQVPHETRSGELLNSGHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00507081;
90% Identity
-
80% Identity
-