Dinn012449.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila innubila
Gene Symbol
L
Assembly
GCA_004354385.1
Location
NW:11404877-11442730[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1e-05 0.00058 19.7 2.9 1 23 257 279 257 279 0.98
2 17 0.36 20 5.5 6.2 1 23 285 307 285 307 0.97
3 17 1.7e-07 9.7e-06 25.3 3.2 1 23 313 335 313 335 0.99
4 17 1.3e-05 0.00071 19.5 0.4 1 23 341 363 341 363 0.99
5 17 0.024 1.3 9.2 0.2 2 23 446 470 445 470 0.90
6 17 0.0011 0.064 13.3 0.2 2 23 500 522 499 522 0.95
7 17 0.028 1.6 9.0 0.7 1 23 617 639 617 639 0.97
8 17 0.0078 0.44 10.7 0.1 2 23 647 668 646 668 0.91
9 17 2.3e-05 0.0013 18.6 0.3 1 23 676 701 676 701 0.93
10 17 4.4 2.5e+02 2.0 1.5 2 23 737 759 736 759 0.94
11 17 0.0026 0.15 12.2 1.1 1 23 810 833 810 833 0.97
12 17 0.0016 0.093 12.8 1.8 2 23 1013 1035 1012 1035 0.96
13 17 0.12 6.6 7.0 0.1 1 23 1041 1063 1041 1063 0.92
14 17 0.34 19 5.5 0.7 2 23 1071 1092 1070 1092 0.95
15 17 0.75 42 4.4 0.5 2 23 1189 1210 1189 1210 0.94
16 17 0.037 2.1 8.6 0.0 1 23 1220 1242 1220 1242 0.96
17 17 0.00022 0.013 15.5 1.2 1 23 1247 1269 1247 1269 0.97

Sequence Information

Coding Sequence
ATGTCACGACGTAAACAGGCAAAGCCGCGCGCCTGCTTGAAACTTGGCGAAAAGGAGGAGGAGAATGGCGAAGGTGGCATCACAAAGTCGCCCAAGGCATCTGATTTGCTTGAGCCCAAAGAGGAGCTATTTAGCGCCGATGAAGAGGATTGCGAGGAGGATGACGAGCCAGAGGATGGCCTCAGTGGCGATGAGAATGAGACTcaaaatgaaattgaaaatgtggcTGACATTGAGGAGGATGTTGATGATTTGCTTAGTCTCAGCGCCGATGAGATAtacgatgatgatgagctGCATAGTCTGGACAGTTTTTACTCAGATATGTACAGCACACACACCTCCTCCAGCTACTCGCCGAGCATCTCGGACGGCACATTGACGCCCAACTCacagcatccacatccacattcgCATCCACAGCTCTCAGCTGCTGGTGAGGATCCTAGCTCTGAGCAGGACAAGGCGAATGGGGACACGGCAACAGCTGCTGATGAggagcgagagagggagagggagagggagcgGGAGCCAGCCAAAATAAAGCGACCCGCTCAtttgcatcatcatcatcatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCAAAGCTCACAGGACCCACAGGAGCTGGAGCAGGAGgcggagcaggagcaggaggaggaggaggacaTGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTCCAGAGCCATGCCGAACATTTGCCTTTCAAATGCGAATACTGCGCCAAGTTATTCAAGCACAAACGTTCCCGAGATCGTCATAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCACATTGCGAGGCCGCTTTTTCCAGAAGcgaCCATCTGAAGATCCACATGAAGACCCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACGGCGGCCGCATTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCAATACTGGCAGCTGGTGGCAACCCTAATGCCCTCAACTACAGTCCACGTAGCACGGGCTCTGCCTCCATCTCCAGCAACGGGAGTCTGCACAAGCGACGCTATGCATTGGCACTCGCCTCCGACAGCAGTCCGAGTCGGATGGAGTATCCGAAACGTGTTCGTGGTCAGGTGGCAACCACACCCGTATCGACAACGACACCGATAGCCACACCGATACCGACTCCTTTGCTGCGTTGCAGCTACTGTCCCAAGGTGACGGAGTTTAGCAGCTTGGAGCAATTGAATGCACATCTGCAGCAGGCacatgagcagcagcagcatcagcagcaggcGAGGATTACGACGACGACTGGCGGGGATGGGGAGACGCAGCAGTCGAATGGCTTCCAGTTGAGCTGCGAGTACTGCACCATGAGATTCGTGAATATCGCGGGATTGTTCCAGCACATGCGTGCCACACACCTGGATCGCCTGAGCAGTCCCAACTCCTACTATGAGCACTTCAATCGTCTGGCCACGGCGGGCACATTCAGTCCACGTCTGGCACTGGAGCTGCCCAAGATTAAGCAGGATTTGGGCAGTCCACAGCAGCGGGAGCAGCGCGAGCAGCGGGAGCAGCGGGAGCAGCTCATGGAGAAGCCGGAACAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGCACAGTGACACCACCAACCACAGCAACCACAATAGCTGCACCACAAGCGCCACCTGGCGTCTTCTTTTGCAATCAATGCAACGCTGGTTTGCCGGACTTTGAAAGCTTCCGTAATCATCTGAAGACACATATAGCCGAGGGCATGCAACTGATCTGTCCCCATTGTGGCCTCAGTCTGCCCGAGCAGAGTGAATATGAACGCCATGTGGTTGCCCATTTCCTGATCACCAGCTCCGAGTTCAATTGCAGTGCCGGCAGCTGTGGCAAATCCTTTAGCAAGTCGGATGAGCTGCAGCAGCATTTGAATAGCGAGCATGTGATGACGCTGCTCAAGTGCATCCTCTGCTCGGAGCTGTGCGAGTCGAGGATGGCCATGCAGCTCCACTTGGCCTGTGCGCACAGCCAGGAGACGAAGCTGTTGCGTTGCAGCGCCTGCATGGAGATCTTTCGCAATGATACGGACTTCCATGTGCATGTCAAGACCAGGCATCAAGGTGGAACAGGCGGAGGGGGAGTGGCAGGAGGAGTGGGAGTGGCAGGAGGAGCTGTTCCCGCTAATCCTTTGCAGTGCATGTTCTGTCGCGCTGTTTGCAACTCCGAGCTGGAGATGCACTTCCATCTGGCGGCACATGCGCGTCAGTTCCGTTGCCCCTCGTGCCCCGAAACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGTCAGCACGGCGGCGTCAAGGAGTCGCCGGCCAAGCAACCCGCCAGTTCACCCAACATGGGCAGTCTGTATGTGAATGCCTTGTTGCCACCGCTGGCGGCAGCtgcagccgctgctgctgtggccaccaacaacaatagcaatctGCATATTGACTACAATGTGGCATTCAAGGGACTCTTTGGCGGAGCAGTTGGTGGTACGGCGGGTGGTGGTGCAGCTGCCACACCCGGTGGCAAGTTCTACAGTCCGCTGCAGGTGGACACGAGTGCGCTGAAGCCACAACAGTCACCACATCCGGCACTCATGTACGGACTGAGTCAACGCTATCTGATGGAGATGTATGCGGCCAAGGCCACGTCTCCGGCGGCGGCAGTTGCTCCGGATGTGCCACAGTCCACGGTTGGTGGCACGGGTGGCACAGCTGTCACCGCAGCCAGTGGCAACTACAGCTGTGGCATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAACTCCATTCGCATCGCAAGTTGGCCCACAATCTGAAGACGGGAGTCAGCTTGAGATGCGCCTATTGCTCCGGCAACTTCAAGTCGCGGGCTGAGCTGGAGCAGCACATGAAGAGTTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTCCCCTCGCCGGCCATTCTCGCAGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCCGGCAAGTGTGCCCACTGTGGCCAGCAGCTGGAGCACGTGGCCGCCTTCCGGGCGCATCTCACCGAGCATGGCGGCGATGGTAATCTGCCCATGGCCTGCATCTGTTGCCGCCAGACGCTGCACTCCGAGTTCGAGCTGAGTCTGCATGCCAAGTTCCACACCAAGTCACCCGGTGGCAGTGCTGGTGGCAGCCTCCAGGAGCCGGTCTGTGCTCTGTGCCTGGAGCCGTTGCCGGGTGCCGGAGAAACAGCCAAACTGTGTGAGAAATGCTGTCGCAAGCACAATCTCAATGGCAAGCGGCACAAGGAACCGACTCCAGTGGGTGCAGCTGCTCCGGCTCCGGCCTACCTGGAGAATCGTTGCAATCTCTGCAAGATGATCTTACCGCATGCCCAGAAACTGCAGGAGCATCTGGTGGAGCACACGTTTGCCGGCACCGAACAGCGTGGCTTCAATTGCTACATCTGCTCCGCCGTCTTTACCGCACCCGCCGGACTCCTCAGCCACATTGCCGAGCACGGTGCTCGTCCCTATGACTGCAATCTGTGCCCCGAGAAGTTCTACTTTCGTGCCGAACTGGAGCATCATCAGCGTGCCCATGAGCTGAGGCCGGCACCTCCTTCAGCTGGACGCATTCCACCCAAGCAGGAGACGCGCAGCTCCTCGGCCAGTTCCCCACTTGCCCCGAGTCCGAGCCATGTCAAGCAGGAGCTCTATGAGTCCGAGACGGCACCGTCACCCGCTGCCGAGGAGCCCTCTGcccaggaggaggaggagtacATTGAAGTGGAGCAGGTGGCGCACGAAACACGTTCCGGAGATCTCCTGAATTCCGCACACACCGAACGTTCCAGCAGCAGCGCCTAA
Protein Sequence
MSRRKQAKPRACLKLGEKEEENGEGGITKSPKASDLLEPKEELFSADEEDCEEDDEPEDGLSGDENETQNEIENVADIEEDVDDLLSLSADEIYDDDELHSLDSFYSDMYSTHTSSSYSPSISDGTLTPNSQHPHPHSHPQLSAAGEDPSSEQDKANGDTATAADEEREREREREREPAKIKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPTGAGAGGGAGAGGGGGHGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMEYPKRVRGQVATTPVSTTTPIATPIPTPLLRCSYCPKVTEFSSLEQLNAHLQQAHEQQQHQQQARITTTTGGDGETQQSNGFQLSCEYCTMRFVNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLGSPQQREQREQREQREQLMEKPEQELPTDLSSNKRRTVTPPTTATTIAAPQAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLITSSEFNCSAGSCGKSFSKSDELQQHLNSEHVMTLLKCILCSELCESRMAMQLHLACAHSQETKLLRCSACMEIFRNDTDFHVHVKTRHQGGTGGGGVAGGVGVAGGAVPANPLQCMFCRAVCNSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKESPAKQPASSPNMGSLYVNALLPPLAAAAAAAAVATNNNSNLHIDYNVAFKGLFGGAVGGTAGGGAAATPGGKFYSPLQVDTSALKPQQSPHPALMYGLSQRYLMEMYAAKATSPAAAVAPDVPQSTVGGTGGTAVTAASGNYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLTEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGGSAGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRHKEPTPVGAAAPAPAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPAPPSAGRIPPKQETRSSSASSPLAPSPSHVKQELYESETAPSPAAEEPSAQEEEEYIEVEQVAHETRSGDLLNSAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00507081;
90% Identity
-
80% Identity
-