Basic Information

Insect: Hirtodrosophila confusa
Gene Symbol: L_1
Assembly: GCA_035043065.1
Location: JAWNNI010000160.1:2113087-2120225[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.2e-05 0.00096 19.9 2.9 1 23 126 148 126 148 0.98

2 17 0.4 33 5.7 6.2 1 23 154 176 154 176 0.97

3 17 1.9e-07 1.6e-05 25.5 3.2 1 23 182 204 182 204 0.99

4 17 1.4e-05 0.0012 19.7 0.4 1 23 210 232 210 232 0.99

5 17 0.014 1.2 10.2 0.2 2 23 307 331 306 331 0.92

6 17 0.0028 0.23 12.4 0.2 2 23 359 381 358 381 0.95

7 17 0.031 2.6 9.1 0.7 1 23 462 484 462 484 0.97

8 17 0.0088 0.72 10.9 0.1 2 23 492 513 491 513 0.91

9 17 4.1e-05 0.0034 18.2 0.3 1 23 521 545 521 545 0.95

10 17 5.9 4.8e+02 2.0 1.6 2 23 581 603 580 603 0.95

11 17 0.0029 0.24 12.4 1.1 1 23 657 680 657 680 0.97

12 17 0.0019 0.15 13.0 1.8 2 23 851 873 850 873 0.96

13 17 0.13 11 7.2 0.1 1 23 879 901 879 901 0.92

14 17 0.38 31 5.7 0.7 2 23 909 930 908 930 0.95

15 17 0.85 70 4.6 0.5 2 23 1025 1046 1025 1046 0.94

16 17 0.036 2.9 9.0 0.0 1 23 1056 1078 1056 1078 0.96

17 17 0.00025 0.021 15.7 1.2 1 23 1083 1105 1083 1105 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.2e-05	0.00096	19.9	2.9	1	23	126	148	126	148	0.98
2	17	0.4	33	5.7	6.2	1	23	154	176	154	176	0.97
3	17	1.9e-07	1.6e-05	25.5	3.2	1	23	182	204	182	204	0.99
4	17	1.4e-05	0.0012	19.7	0.4	1	23	210	232	210	232	0.99
5	17	0.014	1.2	10.2	0.2	2	23	307	331	306	331	0.92
6	17	0.0028	0.23	12.4	0.2	2	23	359	381	358	381	0.95
7	17	0.031	2.6	9.1	0.7	1	23	462	484	462	484	0.97
8	17	0.0088	0.72	10.9	0.1	2	23	492	513	491	513	0.91
9	17	4.1e-05	0.0034	18.2	0.3	1	23	521	545	521	545	0.95
10	17	5.9	4.8e+02	2.0	1.6	2	23	581	603	580	603	0.95
11	17	0.0029	0.24	12.4	1.1	1	23	657	680	657	680	0.97
12	17	0.0019	0.15	13.0	1.8	2	23	851	873	850	873	0.96
13	17	0.13	11	7.2	0.1	1	23	879	901	879	901	0.92
14	17	0.38	31	5.7	0.7	2	23	909	930	908	930	0.95
15	17	0.85	70	4.6	0.5	2	23	1025	1046	1025	1046	0.94
16	17	0.036	2.9	9.0	0.0	1	23	1056	1078	1056	1078	0.96
17	17	0.00025	0.021	15.7	1.2	1	23	1083	1105	1083	1105	0.97

Sequence Information

Coding Sequence: ATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCGGATGGCACACTGACGCCCAATTCGCATCAACAGCTGGCGGCTGTTGCCACACAAGGATCCGAGGATCCCACATCGGAGGAGGCCAAGGCAAATGGCGAGCCTGCTGTGCGGCAGGAGGAGCATGAGCCGGCGAAGCCAAAGCGACCCTCCCATctgcatcatcatcaccatcattACCACCATCAGCAGGCGCTGAAAATTGCCAACAAGCTGCGGAAAATCAATAAGGATGCAAAGCTAGCGGCTGCCGCAGGACTAGGAGGACATGGAGCGGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGCCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAGCATTTGCCCTTCAAGTGCGAATACTGCGCCAAGCTTTTCAAGCACAAACGCTCCCGAGATCGCCATAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCGCATTGTGAGGCAGCTTTCTCGAGAAGCGATCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACGGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCGATCCTGGCCGCTGGCGGCAATCCCAACGCCCTCAACTACAGTCCACGATCCACGGGCTCCGCCTCCATATCTAGCAATGGGAGCCTGCACAAGCGCCGCTATGCGCTGGCCCTCGCCTCCGACAGCAGCCCCAGCCGGCTGGAGTTCCCCAAGCGGGCGCGTGCCCATGCCAATGCCACTGGCACGCCCACACCGACGCCGCTGCTGCGCTGCAGCTACTGCCCCAAGGTTACAGAGTTCACCAGCCTGGAGCAGCTGAATGCGCATCTGCAGAGCGCCCACGAGCAGCTGTCCCGGAGCACGAGCACGACAACGGCCGCCGGGGGAGATGGGGAGGGCGGCAATGCGAATGGCTTCCAGCTAAGCTGTGAGTACTGCACGATGAAGTTTGGCAACATTGCCGCACTGTTCCAGCACATGCGTGGCACCCACCTGGACCGCCTGAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACGGCGGGCACCTTCAGTCCCCGGCTGGCCATGGAGCTGCCCAAGATCAAGCAGGACCTGGCCAGTCCACAGCGGGAGCAGGTCGCGGAGAAGCCGGAACAGGAGCTGCCCACGGATTTGAGCAGCAACAAGCGACGCACCGTGACCCCACCAGAGCCCCAAGCCAATGCCGCCCCGCCGGGCGTCTTCTTCTGCAATCAATGCAACGCGGGCCTGCCGGACTTTGAGAGCTTTCGGAATCATCTGAAGACGCACATTGCCGAGGGCATGCAGCTGATCTGTCCACACTGTGGGCTCAGCCTACCCGAGCAGAGCGAGTACGAGCGGCATGTGGTGGCCCACTTTCTGATCAGCAGCACGGAGTTCAATTGCAGCGCCAGCTGCGGCAAGTCCTTTGCCAAATCGgacgaactgcagcagcatttGAACAGCGAGCATGTGCTGACCCTGCTGAAGTGCGCCCTGTGCTCGGAGCTCTGCGAGAATCGCATGGCCATGCAGCTGCATCTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTGTTCCGCAACGATACCGACTTCCATGTGCATGTCAAGACGCGACATCAGCTGGGCAATCAGCTGAGCTCCAGCGCGGGCAACGGTCCTGGCAATGCTGTTGGCCCAGGTCCTGGCCCGGCCAATTCCTTGCAGTGCATGTTCTGTCGCGCCGTCTGCTCCTCCGAGCTGGAGATGCACTTCCATTTGGCGGCGCATGCGCGACAGTTTCGCTGCCCCTCCTGCCCCGAAACGTTCCATGTGGAGTTTCTGCTGGACAGACACATGCAGAGCCAGCATGGCGGCGCCAAGGACAAGGAGCCCAGCTCCCCCAACATGGGCAGCCTCTATGTGAACGccctgctgccgccgctggccgccgctgccgccgccgccgctgcggcaaccaacaacaacagcagcctgCACATCGACTACAATGTGGCCTTCAAGGGCTTGTTTGGCTCGTCGCCCGCCGCGCCCGCCAGCGCCCAGTCAGCCGGCCAGAAGTTCTATAGTCCACTGCAGGTGGACACCAGCGGCATGAAGCCGCAGCAGTCGCCGCATCCAGCGCTCATGTATGGCCTCAGCCAGCGCTACCTGATGGAGATGTATGCGGCCAAGGCCACATCGCCGGCGGCCAGTGCACCCGAGCTGCCCGCCCCGGCGATCCAGGGGAACAATGCCGCTGCCTCCAGTGGGGGCAGCAGCTACAGCTGCGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTCCACTCGCATCGCAAGCTGGCCCACAATCTGAAGACGGGCGTCAGCTTGAGATGCGCCTACTGCTCGGGCAACTTCAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATTTGCGATGAGATCTTTCCATCGCCGGCCATACTGGCCGAGCACAAGCTCCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGTGCCCATTGTGGCCAGCAGCTGGAGCATGTGGCCGCCTTTCGGGCCCATCTCACCGAGCATGGCAGCGATGGCAATCTGCCGATGGCCTGCATCTGTTGCCGCCAAACGCTGCACTCGGAGTTTGAGCTCAGCCTGCATGCCAAGTTCCATACGAAGTCGCCCAGCTGTGGCAGCCTCCAGGAGCCGGTGTGTGCCCTGTGCCTGGAGCCGCTGCCAGGTGCTGGTGAGACGGCCAAGCTGTGCGACAAATGCTGCCGCAAGCACAATCTCAATGGCAAGCGCAGCAAGGAGTCGGCTCCTGTGGCGGCGCcggctgccactgccaccgccTATTTGGAGAATCGTTGCAATCTGTGCAAGATGATATTGCCGCATGCACAGAAGCTGCAGGAGCATCTGGTGGAGCACACCTTTGCCGGCACCGAACAGCGCGGCTTCAATTGCTATATTTGCTCCGCTGTCTTCACGGCACCCGCCGGCCTCCTCACCCACATAGCCGAGCATGGCGCTCGTCCCTATGACTGCAATCTGTGCCCCGAAAAGTTCTACTTTCGCGCCGAGCTGGAGCATCATCAGCGCGCCCACGAGCTGAGACCGCCTCCAGCTCCAGTACGCGCTGCCCCAACACTGCCCAAACAGGAAACACTCAGCTCCGCGGCCAGTTCCCCCATCGCACTCAGTCCCAGCCACGTCAAGCAGGAGCTGTATGAGCCGGAGACGGCCTCCTCACCCACCCCCGAGCCGCCCGCccaggaggaggaggagtaCATTGAGGTGGAGCAGGTGCCCCACGAAACCCGCTCCGGTGAGCTGCTCTCCTCCGCACACACCGAacgctccagcagcagcgcctaA
Protein Sequence: MYSTHTSSSYSPSISDGTLTPNSHQQLAAVATQGSEDPTSEEAKANGEPAVRQEEHEPAKPKRPSHLHHHHHHYHHQQALKIANKLRKINKDAKLAAAAGLGGHGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARAHANATGTPTPTPLLRCSYCPKVTEFTSLEQLNAHLQSAHEQLSRSTSTTTAAGGDGEGGNANGFQLSCEYCTMKFGNIAALFQHMRGTHLDRLSSPNSYYEHFNRLATAGTFSPRLAMELPKIKQDLASPQREQVAEKPEQELPTDLSSNKRRTVTPPEPQANAAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLISSTEFNCSASCGKSFAKSDELQQHLNSEHVLTLLKCALCSELCENRMAMQLHLACAHSQETKLLRCSACLELFRNDTDFHVHVKTRHQLGNQLSSSAGNGPGNAVGPGPGPANSLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGAKDKEPSSPNMGSLYVNALLPPLAAAAAAAAAATNNNSSLHIDYNVAFKGLFGSSPAAPASAQSAGQKFYSPLQVDTSGMKPQQSPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAPAIQGNNAAASSGGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLTEHGSDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRSKESAPVAAPAATATAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPPPAPVRAAPTLPKQETLSSAASSPIALSPSHVKQELYEPETASSPTPEPPAQEEEEYIEVEQVPHETRSGELLSSAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507081;
90% Identity: iTF_00805375;
80% Identity: -