Dsia011480.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila siamana
Gene Symbol
L
Assembly
GCA_035047445.1
Location
JAWNPP010000081.1:1613685-1622185[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1e-05 0.00068 19.8 2.9 1 23 189 211 189 211 0.98
2 17 0.39 23 5.5 6.2 1 23 217 239 217 239 0.97
3 17 1.9e-07 1.1e-05 25.4 3.2 1 23 245 267 245 267 0.99
4 17 1.4e-05 0.00083 19.5 0.4 1 23 273 295 273 295 0.99
5 17 0.039 2.3 8.6 0.2 2 23 378 402 377 402 0.91
6 17 0.0012 0.074 13.4 0.2 2 23 427 449 426 449 0.95
7 17 0.03 1.8 9.0 0.7 1 23 542 564 542 564 0.97
8 17 0.0057 0.34 11.3 0.1 2 23 572 593 571 593 0.91
9 17 7.2e-05 0.0043 17.2 0.3 1 23 601 626 601 626 0.93
10 17 5.7 3.4e+02 1.8 1.6 2 23 662 684 661 684 0.95
11 17 0.0028 0.17 12.2 1.1 1 23 736 759 736 759 0.97
12 17 0.0018 0.11 12.9 1.8 2 23 953 975 952 975 0.96
13 17 0.13 7.6 7.0 0.1 1 23 981 1003 981 1003 0.92
14 17 0.61 37 4.9 0.4 2 23 1011 1032 1010 1032 0.93
15 17 0.81 49 4.5 0.5 2 23 1136 1157 1136 1157 0.94
16 17 0.04 2.4 8.6 0.0 1 23 1167 1189 1167 1189 0.96
17 17 0.00036 0.022 15.1 1.1 1 23 1194 1216 1194 1216 0.97

Sequence Information

Coding Sequence
ATgatggctttaaaaatgttatatcGCGGTCCCAGTTCGCGTTtggaaaatttaattgaaaagatTCAAGCCACGAAGGAGATTTCCAATAACGACATGTACAGCACTCACACCTCCAGCAGCTACTCGCCCAGCATTTCGGACGGCACTTTGACGCCCAACtcacagcagctgcatccGCAGCTCTTGGCAGCTGGCGAGGATCCGGGTGTAGAGCAGTCCAAGCTAAATGGCGACACCACAGCCGCTGCAgtcgaggaggagcaggagcgcGAAAGGGAGCGgaacagggacagggacagagaaAGGGAGCCACTCAAGCTGAAGCGACCCGCCCACTtgcatcaccatcatcatcattaccaTCATCAGCAGGCGCTGAAAATTGCCAACAAGTTGCGTAAAATCAATAAGGAAGCAAAGCTCACAGGacccacagcagcagctggcggcggaggcggaggcggcgcCGGAACTGGAGCTGGTGGCGGCAACAGTggcgcagcagccgcaaagtTTGATAAGTTGACAGGCGAAGGCATTAAGAGCCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGCGACAAATCATTTCCACGACTCGGTTACTTGAAGCATCACGTCCAGAGCCATGCCGAGCATTTGCCTTTCAAATGCGAATACTGCGCCAAGCTGTTCAAGCACAAGCGTTCCCGCGATCGGCATAAGAAGCTCCACACCAACGAGCGGAACTACAAGTGTCCGCACTGCGAAGCCGCTTTCTCCCGAAGCGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACCGCCGCCGCGCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCCATCCTGGCAGCCGGCGGCAATCCCAACGCCCTCAACTACAGTCCGCGCAGCACCGGCTCCgcctcggcctcggcctcCATCTCGAGCAACGGCAGCCTGCACAAGCGACGCTATGCGCTGGCCCTCGCCTCCGACAGCAGCCCGAGTCGCCTCGATTATCCGaagcgcagtcgcagccacgCCCACGTGCCCAGCACGCCCACGCCAACGCCCTtgccgacgccgctgctgcgctgcagctACTGCCCCAAGCCAATGGAGTTCAGCAGCCTGGAGCAGCTCAATGCGCATCTGCAGCAGTCACACGAACAGCCCAGCACAACGGAGCCCAACACTGGCGAGTTGGACGCAAAGGCGCAGGCGAATGGCTTCCAGCTGAGCTGTGAGTACTGCACGATGCGCTTCGTCAACATTGCCGGCCTGTTCCAGCACATGCGCGCCACGCATCTGGATCGCCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACGGCTGGCACGTTCAGTCCCCGGCTGGCGCTCGAGCTGCCCAAGATCAAGCCCGATCTGGGCAGTCCACAGCGTGAGCGTGAGGCGCTAGAGAAACCCGAGCAGGAGCTGCCCACCGATCTGAGCAGCAATAAGCGTCGCACAGTGTCGCCCCCTGGCACTCAgactggagctgctgctgccgctgccgcccaggtcgcagcgccagcgccaccTGGCGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCGGACTTCGAGAGCTTTCGCAATCATCTGAAAACGCACATTGCCGAAGGCATGCAACTGATCTGTCCACACTGCGGCCTCAGTCTGCCCGAACAGAGCGAATTCGAGCGTCACGTGGTCGCCCACTTCCTCATCGCTAGCTGCGAGTTCAACTGCAGCGCCTCCAGCTGCGGCAAATCCTTTGCCAAGTCCgacgagctgcagcagcatctgaACAGCGAGCACGTGCTGACGCTGCTGAAGTGCGCGCTATGCGCCGAGATCTGCGAGACGCGCATGGCCATGCAGCTGCATCTGGCCTGCGCCCACGGCCAGGAGACGAagctgctgcgctgcagcGCCTGTCTGGAGCTCTTCCGCAACGACACCGACTTCCATGTGCACGTGAAGACGCGCCACCAGCTCGCTGGCAATCAACTCGCCGCAGCCTCCGCTGCACCCGGCCACGTGCAGCCAGCGAGCGCTGGCAATCCGCTGCAGTGCATGTTCTGTCGCGCCATTTGCGCCTCGGAGCTGGAGATGCACTTCCATCTGGCAGCGCATGCGCGCCAGTTTCGCTGTCCCTCCTGTCCCGAGACCTTCCACGTCGAGTTCCTGCTCGACCGGCACATGCAGAGCCAGCACGGCGGCGGTgtcggcgttggcggcgtcaAGGAGCGCACACCGCCCAAGGACAGCTCGCCCAGCATGGGCAGCCTCTATGTGAacgcgctgctgccgccgctggccgcagctgctgcggctgccgccgccgccagcgccacaaacaacaacagcaacctgCACATCGACTACAACGTGGCCTTCAAGGGCCTCTTCGGCGGCACAGGCGCAGGCACTGCTGGCGCCCCCGGCGGCAAGTTCTACAGCCCGCTGCAGGTGGACACGAGTGGCCTGAAGCCACAGCACTCACCGCATCCGCATCCAGCGCTGATGTATGGCCTCAGTCAGCGCTATCTGATGGAGATGTACGCCGCCAAGGCCACCTCACCAGCGGCAGCCAATGGGCCCGAGGCGCCCGCCCAGacgcagcaggcagcagccccaggtggaggaggaggcggagcaGGAGGCGCCACAGCGGCTGGCAATGCGAGCGGCAGCTACAGTTGCGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTGCACTCGCATCGGAAGCTGGCCCACAATCTGAAGACAGGCGTCAGCCTGAGGTGCGCCTATTGTTCGGGCAACTTCAAGTCGCGCGCCGAGCTGGAGCAGCACATGAAAAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCCGCCATACTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCGGGCAAGTGCGCCCACTGcggccagcagctggagcacgTGGCCGCCTTTCGCGCCCATCTCGGCGAGCATGGCGGCGACGGCAGTCTGCCAATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCGGAGTTCGAGTTGAGTCTGCACGCCAAGTTCCACACCAAGtccagcggcggcggcggcagcggcatcggcgTCCAGGAACCCGTCTGCGCCCTCTGCCTGGAGCCGCTGCCCGGCGCCGGCGAGACGGCCAAGCTGTGCGACAAGTGCTGTCGCAAGCACAACCTCAATCTGAACGGCAAGCGCAGCGCCAAGGAAGcggctccagcagcagcggcgccagcaGGCGTGACGAACGCCAGCTACCTGGAGAATCGCTGCAACCTCTGCAAGATGATACTGCCGCACGCCCAGAAGCTGCAGGAGCACCTTGTGGAGCACACGTTCGCCGGCACCGAGCAGCGTGGCTTCAACTGCTACATCTGCTCGGCGGTCTTCACGGCGCCCGCCGGCCTGCTCAGCCACATTGCGGAGCACGGCGCCCGGCCCTACGACTGCAGCCTGTGCCCCGAGAAGTTCTACTTTCGCGCCGAGCTCGAGCACCATCAACGCGCCCACGAGCTGCGACCAGCTGCAGTTCCTGTCTCCGTGTCGCACCCACCACTGCCAGTTGCTGCGCCGCCAGCTGCACCAGCTGCGCGCGTTGCCAAGCAGGAGACGCGCAGCTCGTCGGCTAGCTCGCCCATCATCGCGCTCAGTCCGAGCCACGTCAAGCAGGAGCTCTATGAGTCAGAGACGGCTGGCTCGCCGCCCGCCAATGAGGCGCCCGCGCAGGACGACGAGGAGTACATCGAGGTGGAGCAGATGCCGCTCGAGACGCGTGCCGCGGAGCTGTTGACGGCCGCGCACACCGAACGCTCTAGCAGCAGCGCCTAA
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTLTPNSQQLHPQLLAAGEDPGVEQSKLNGDTTAAAVEEEQERERERNRDRDREREPLKLKRPAHLHHHHHHYHHQQALKIANKLRKINKEAKLTGPTAAAGGGGGGGAGTGAGGGNSGAAAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASASISSNGSLHKRRYALALASDSSPSRLDYPKRSRSHAHVPSTPTPTPLPTPLLRCSYCPKPMEFSSLEQLNAHLQQSHEQPSTTEPNTGELDAKAQANGFQLSCEYCTMRFVNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPQREREALEKPEQELPTDLSSNKRRTVSPPGTQTGAAAAAAAQVAAPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLIASCEFNCSASSCGKSFAKSDELQQHLNSEHVLTLLKCALCAEICETRMAMQLHLACAHGQETKLLRCSACLELFRNDTDFHVHVKTRHQLAGNQLAAASAAPGHVQPASAGNPLQCMFCRAICASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVGVGGVKERTPPKDSSPSMGSLYVNALLPPLAAAAAAAAAASATNNNSNLHIDYNVAFKGLFGGTGAGTAGAPGGKFYSPLQVDTSGLKPQHSPHPHPALMYGLSQRYLMEMYAAKATSPAAANGPEAPAQTQQAAAPGGGGGGAGGATAAGNASGSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGGDGSLPMACICCRQTLHSEFELSLHAKFHTKSSGGGGSGIGVQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNLNGKRSAKEAAPAAAAPAGVTNASYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHIAEHGARPYDCSLCPEKFYFRAELEHHQRAHELRPAAVPVSVSHPPLPVAAPPAAPAARVAKQETRSSSASSPIIALSPSHVKQELYESETAGSPPANEAPAQDDEEYIEVEQMPLETRAAELLTAAHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00507081;
90% Identity
-
80% Identity
-