Dari000271.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila arizonae
Gene Symbol
Lztr1
Assembly
GCA_001654025.1
Location
NW:17658887-17663930[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 3.2e-14 6.1e-12 45.1 0.8 1 107 560 700 560 703 0.88
2 4 0.32 61 3.3 0.2 77 109 702 734 698 735 0.90
3 4 7.6e-20 1.4e-17 63.2 0.0 8 97 794 883 788 898 0.85
4 4 5.5 1e+03 -0.7 0.0 72 100 892 920 886 928 0.84

Sequence Information

Coding Sequence
ATGCTTAAGTCCATACTTGGCGCAGACTCGAATGGTTCTGCGGAAGATCTACCAAGCGgaggcgttggcgttggcgttgtcGTGGCCAGCGGCAGTAGCGGAGgaagtggcagtggcagcagccgcagtgcTGGAGCGCTAAGCCGAGCCAGTTACGGCCACGGCTCCAGCTCAATATCGAGTGGTCTAAGTGCGGTTTGTGGCTTAGTCGGAAGCGGCAGCGgtagcggcagtggcagtggcagtgcaAGTGCTAGTGCAAGTGGTGGCAGCACACCAGCTACCGTCTATTGTCCTGCATGCGTGGCGAACAgttcacagcaacagcagcagcaacagcaggcacTTGCCTCTGGCGCTGAGGGCCTGACAGCGCGCGAGTCCAAATCAGGGAAGCGGGCTAAGACGCGGAAGAGTGCATCAACGGCTGGCTGCTTGGACGCTCAACATATACGCAACCATCTAAAAATGTCCACATCGAGCTCCATGCGCAGCACCCGCGGCAACGGtgccggcggcagcagcagcagcagtagcaccaCCTCGGCTGTTATACCAtccggctgcagcagcatcgccTACGATtccaacagcaatggcagctgcagcagcttcaacGGCAAAGTCAACTCGCCaggcagctacagctgcaatGCGCTCAATGTCGACTTCAGCACCTATACGGCAACGCACCAGTGGTCGCGCATGCTTGAGTGTGCGGAGTTTGTCGGTGCCAAACGAAGCAAGCACACTGTGGTTGCCTACAAGGATGCCATGTTCGTGTTTGGCGGTGACAATGGCAAGACCATGCTCAACGATCTGATTAGGTTCGGTGTGAAGGATAAGTCCTGGGGACGTGCATGCGCAACGGGCACACCGCCAGCTCCGCGCTACCATCATTCGGCAGTTGTGGCGGGCAGCTCGATGTTCATCTTTGGCGGCTACACAGGCGACATTCACTCCAACTCGAATCTGACCAACAAGAATGATCTGTTTGAGTATAAGTTTCTCAGCGCCATGTGGGTGGAATGGAAGTTTTCCGGCAGGCAGCCAGTGCCACGTTCTGCGCATGGTGCCGCCGTCTATGATAACAAAATGTGGATTTATGCTGGCTATGATGGCAATGCACGATTGAATGATATGTGGACTTTGAATTTGACGGGCGAGAATCATCAGTGGGAAGAGGTAGAACAGCTAGGTGATCGTCCGCCCACTTGCTGTAATTttcccgttgctgttgctcgcgattgtatgtatgtgttctcTGGCCAGAGTGGTTTGCAGATCACCAATTCTCTGTTTGAGTTCCACTTTAAGTCGCGCACTTGGCGTCGCATCTCCAACGAGCCGGTTCTGCGTGGTGCCACCTCTGCGCCACCATCGCGTCGCTATGGCCACACCATGGTGCATCATGATCGTTTCCTCTATGTTTTCGGCGGCTCGGCTGACTCCATGCTCCCAAATGATTTGCACTGCTACGATCTGGACTCGCAGGTATGGTCCGTCATACAGCCGGAGCAGAACTCGGATGTGCCATCGGGACGCGTTTTCCATGCCTCGGCCGTCATCAGCGATGCCATGTACATCTTTGGCGGCACCGTTGACAACAGCGTGCGACGCGGCGATACCTATCGCTTTCAGTTCTCCAGCTATCCAAAGTGCACGCTGCGCGATGACTTTGGCAAATTCTTTCACGAGAAACAGTTCTGTGATATCCAGTTTGTGGTGGGTGCCGAGGAGACGCGTATTCTGGCCCACATTGCCTTTGTGGCAGCACGCTCTAAGTATTTGCGGAACAAGATATTGTCGGCGCGTGAGGCGCTCCAGCATCAAATGGAAAAGCTCTATGGCGTTGGCCAGGTCGATGCGCTTGCTTTGAATACGGGCGTTGGCGCCGATCGTACACCGATGCTGGAAGTGCGACTATCACATGCCTCGCCCGAAGCATTCGAAATCATACtcaactacatatatacggaTCGCATTGACTTAAAGGAGTCCTACAACAAGAACATCATCATTCTCATCACGGACATCTATCAATTGGCTGGGCTTTTCACAATGCCCCGTCTGGCGCAGGGCTGCATACAGTATCTGGACTTTAAGATCAATAAGATGAACGTGCTCGAGGCTCTCTACAATGCGGAAAAGAACAACATTAAAATCATCAAGGATCATTGCATGCAGTTCATCATCAAAGACGAGAACTTCACCGATGTGGTCATGTCCAGTGAGTTTAGCGATCTAGACAAGCCGCTTCTGGTCGAGATAATACGCAAGCGTCTGCATCCCAGCAAACTGGTCATGGACACCAGCTTTGAGTCGAATATTGgtaCCACATTGGAGCACGATTTGTCCATGTTCTTAGAGACAACGGGCAAGGACTTCTGCGATATAAGTCTGATTCTGGATGATCAGGTGATACCGGCCCATAAGTCTGTCCTATCAGCCCGTTGCACCTATTTCCAGGGCATGTTCCGCTCGTTCATGCCGCCGGATAATACAGTCAATATACAAATTGGCGAAATTTCACCCTCGCTGGAGGCGTTTCACTCGCTGCTacgctatatatattatggagAGACAAAGATGCCGCCGCAGGATGCACTCTATCTGTTCCAGGCACCCTGTTTCTATGGCCTATCGAATAATCGCTTGCATGCGTTCTGCAAATACTCATTGGAGCATAATATAACATCAGAGAATGTGCTGCAAACGCTGGAGGCGTCCGATATAACTAAAATCTATGACATCAAGGATTAtgcattgaaattaattgtgAAAGATTTTGCCAAGGTGGCCAGGCTACCAAAGATAGCCGGTTTGTCGCGCGAACTGTTGCTGGAGATAATACGCGCTGTGGCCGATTCGCAAGGCGAGTTTCTGACCCGCATCAATATCAATACAGATATCTGA
Protein Sequence
MLKSILGADSNGSAEDLPSGGVGVGVVVASGSSGGSGSGSSRSAGALSRASYGHGSSSISSGLSAVCGLVGSGSGSGSGSGSASASASGGSTPATVYCPACVANSSQQQQQQQQALASGAEGLTARESKSGKRAKTRKSASTAGCLDAQHIRNHLKMSTSSSMRSTRGNGAGGSSSSSSTTSAVIPSGCSSIAYDSNSNGSCSSFNGKVNSPGSYSCNALNVDFSTYTATHQWSRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKTMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFLSAMWVEWKFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENHQWEEVEQLGDRPPTCCNFPVAVARDCMYVFSGQSGLQITNSLFEFHFKSRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYVFGGSADSMLPNDLHCYDLDSQVWSVIQPEQNSDVPSGRVFHASAVISDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFHEKQFCDIQFVVGAEETRILAHIAFVAARSKYLRNKILSAREALQHQMEKLYGVGQVDALALNTGVGADRTPMLEVRLSHASPEAFEIILNYIYTDRIDLKESYNKNIIILITDIYQLAGLFTMPRLAQGCIQYLDFKINKMNVLEALYNAEKNNIKIIKDHCMQFIIKDENFTDVVMSSEFSDLDKPLLVEIIRKRLHPSKLVMDTSFESNIGTTLEHDLSMFLETTGKDFCDISLILDDQVIPAHKSVLSARCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKMPPQDALYLFQAPCFYGLSNNRLHAFCKYSLEHNITSENVLQTLEASDITKIYDIKDYALKLIVKDFAKVARLPKIAGLSRELLLEIIRAVADSQGEFLTRININTDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00549605; iTF_00554438; iTF_00551643; iTF_00473120; iTF_00595301; iTF_00509155; iTF_00614244; iTF_00598214; iTF_00579335; iTF_01555467; iTF_01319820; iTF_00520688; iTF_00553778; iTF_00562525; iTF_00589598; iTF_00472415; iTF_00575644; iTF_01554021; iTF_00586022; iTF_01559816; iTF_00569033; iTF_00510603; iTF_00506927; iTF_00470931; iTF_00502580; iTF_00610710; iTF_00528863; iTF_00612869; iTF_00531714; iTF_00593890; iTF_00492291; iTF_00536099; iTF_00915396; iTF_00604901; iTF_00555143; iTF_00606375; iTF_00914567; iTF_00916296; iTF_00609225; iTF_00541130; iTF_00617706; iTF_00594604; iTF_00525933; iTF_00569741; iTF_00586733; iTF_00501102; iTF_00491567; iTF_00919119; iTF_00485200; iTF_00488720; iTF_00571954; iTF_00489428; iTF_00524469; iTF_00590294; iTF_00600374; iTF_00478071; iTF_00490136; iTF_00561817; iTF_00565434; iTF_00604154; iTF_00917274; iTF_00486619; iTF_00487355; iTF_00602651; iTF_00613564; iTF_00483038; iTF_00533150; iTF_00527359; iTF_00514945; iTF_00525185; iTF_00566145; iTF_00904801; iTF_00573378; iTF_00619202; iTF_00607845; iTF_00591752; iTF_00478787; iTF_00515651; iTF_00587460; iTF_00588900; iTF_00804452; iTF_00501861; iTF_00553094; iTF_00564711; iTF_00598939; iTF_00616255; iTF_01321253; iTF_01324973; iTF_01327954; iTF_00483751; iTF_00577840; iTF_00591026; iTF_00504743; iTF_00508391; iTF_00519975; iTF_00578599; iTF_00596712; iTF_00592444; iTF_00539712; iTF_00603400; iTF_00476681; iTF_00488074; iTF_00512778; iTF_00539018; iTF_01326474; iTF_01321991; iTF_01322714; iTF_01324188; iTF_01554762; iTF_01553290; iTF_01559094; iTF_00493707; iTF_00599645; iTF_00534635; iTF_00563229; iTF_00537579; iTF_00583019; iTF_00526636; iTF_00616959; iTF_00538285; iTF_00484494; iTF_00495918; iTF_00561095; iTF_00535374; iTF_00511337; iTF_00532431; iTF_01548911; iTF_01551786; iTF_01552510; iTF_00528112; iTF_00572656; iTF_00611408; iTF_00500369; iTF_01319090; iTF_00475987; iTF_00477388; iTF_00505459; iTF_00507667; iTF_00480916; iTF_00517766; iTF_00473837; iTF_00471675; iTF_00522229; iTF_00545301; iTF_00544550; iTF_00568309; iTF_00601109; iTF_00901559; iTF_01556183; iTF_00482296; iTF_00506168; iTF_00546712; iTF_00581592; iTF_00474554; iTF_00481594; iTF_00615620; iTF_00546021; iTF_00504047; iTF_00614961; iTF_00550303; iTF_00503322; iTF_00612130; iTF_00571214; iTF_00559546; iTF_00574875; iTF_00580793; iTF_00584475; iTF_01323451; iTF_01549627; iTF_00805244; iTF_00803658; iTF_00490834; iTF_00802906; iTF_00531007; iTF_00512061; iTF_00494442; iTF_00588203; iTF_00529618; iTF_00548125; iTF_01327229; iTF_00548862; iTF_00574110; iTF_00605630; iTF_00536827; iTF_01325726; iTF_01356191; iTF_00498208; iTF_00555904; iTF_00563968; iTF_00580032; iTF_00832230; iTF_00582312; iTF_00556595; iTF_00493012; iTF_00509876; iTF_00601859; iTF_00523009; iTF_00516322; iTF_00533859; iTF_00540425; iTF_00567593; iTF_00585257; iTF_01551055; iTF_01557618; iTF_00608499; iTF_00519220; iTF_00557973; iTF_00547414; iTF_00541816; iTF_01550332; iTF_00560346; iTF_00495172; iTF_00566853; iTF_00521416; iTF_00558728; iTF_00593162; iTF_00497451; iTF_01320526; iTF_00513520; iTF_00597425; iTF_00607124; iTF_00499637; iTF_00496662; iTF_00517046; iTF_00576406; iTF_00570455; iTF_00595992; iTF_00577113; iTF_00609945; iTF_00619898; iTF_00485917; iTF_00518494; iTF_00542496; iTF_00543808; iTF_00339221; iTF_00338403; iTF_00336811; iTF_00337593; iTF_00335963; iTF_00806026; iTF_01570295;
90% Identity
iTF_00561095;
80% Identity
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