Basic Information

Insect: Scaptomyza caliginosa
Gene Symbol: Lztr1
Assembly: GCA_035044725.1
Location: JAWNNR010000892.1:214855-218193[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 3.7e-13 8.3e-11 41.9 0.3 2 108 552 692 551 694 0.88

2 4 0.44 99 3.0 0.1 78 108 694 724 690 726 0.90

3 4 2.3e-19 5.3e-17 61.9 0.0 8 97 785 874 779 889 0.85

4 4 6.2 1.4e+03 -0.7 0.0 72 100 883 911 877 919 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	3.7e-13	8.3e-11	41.9	0.3	2	108	552	692	551	694	0.88
2	4	0.44	99	3.0	0.1	78	108	694	724	690	726	0.90
3	4	2.3e-19	5.3e-17	61.9	0.0	8	97	785	874	779	889	0.85
4	4	6.2	1.4e+03	-0.7	0.0	72	100	883	911	877	919	0.84

Sequence Information

Coding Sequence: ATGCTAAAGTCCATACTTGGTGGGGACACGAATGATTCTGCGGAAGATATACCAACCGGAGGTGTTGGCGGCAGGAGTGCCAGaggaggcagcagcagcggaggtagtggcagcggcggcagcggtcGAAGCACCAACAGTGCAAGCGCATTCAGCCGAGCCAGTTGCGGTCTTGGTTCCAGCTCAATATCCAGTGGCTTAAGTGCCGTATGTGGCCGCTcaggcagtggcagcggcagcgcaagtgccagtgccagtggtAGCAGTACACCAGCAACCGTTTATTGTCCTGCATGCGTAGCCAGCAGTTCGCAGCAACAACCAGAGGCATTGCATCAGCGGGATTCAAAGACAGGAAAGCGGCAAAAGCCGCGCAAAAGTGCATCGACAGCTGGCTGCGTAGACGTGCAGCATATACGTAACAATCTGAGCATGTCTACATCAATCTCGACGCGCAGCACtcgcggcagcagcaacagcagctgcagcactgCATCTGCCAGTGCCTCCGCCATGATGCAATGCAGCAATGGCATTGCGTATGATGCCAATAGCAACGGGAGCTGCAACAGTAGCACTTTCAATTACAAAGACAGCCCGCCGGGCAGCTATAGCTACAGCTGCAATGCTCTCAACGTTGACTTTAACTCCTATACGGCAACGCATCAGTGGACGCGCATGCTCGAATGTGCCGAGTTCGTTGGCGCCAAACGCAGCAAGCATACGGTGGTTGCCTATAAAGATGccatgtttgtgtttggcgGCGATAATGGCAAGAATATGCTTAACGATCTGATTCGGTTTGGTGTCAAGGACAAGTCATGGGGACGAGCGTGTGCAACTGGTACGCCTCCTGCGCCACGCTATCATCATTCTGCTGTTGTCGCCGGTAGCTCGATGTTCATCTTTGGCGGCTATACGGGCGACATACACTCCAATTCGAATCTGACCAACAAGAATGATTTGTTTGAGTACAAGTTTCTTAGCGCCATGTGGGTGGAGTGGAAATTCTCGGGCAGGCAACCGGTTCCACGTTCGGCGCATGGCGCAGCTGTTTATGATAACAAAATGTGGATTTATGCCGGTTATGATGGTAATGCTCGATTAAACGATATGTGGACGCTAAATTTAACCGGCGAGAATCATCAGTGGGAGGAGGTCGAACAACAAGGAGATCGTCCGCCCACTTGCTGCAATTttcccgttgccgttgcacgCGATGCCATGTATGTGTTCTCTGGGCAGAGTGGTCTACAGATAACCAATTCACTCTTTGAGTTCCACTTCAAGACGCGCACTTGGCGTCGCATTTCCAATGAACCAGTGCTGCGTGGCGCCACATCGGCGCCACCATCCCGTCGCTATGGCCACACAATGGTTCATCACGATCGTTTTCTTTACATATTTGGCGGCTCAGCAGATTCAACGCTGCCAAATGATTTACACTGCTATGATCTAGACTCGCAGGTATGGTCCGTCATACAGGCGGAACAGAACTCAGATATGCCTTCGGGTCGTGTTTTCCATGCATCAGCAGTAATTGGTGATGCCATGTACGTCTTTGGCGGCACCGTTGACAATAGCGTGCGACGTGGCGATACATATCGCTTTCAGTTCTCCAGCTATCCAAAGTGCACGCTGCGCGATGACTTTGGCAAGTTTTATCACGAGAAGCAATTCTGTGACATACAGTTTGTGGTTGGTGCTGAGGAGATACGTATACAGTCGCACATTGCCTTTGTTGCGGCACGCTCCAAGTATTTGCGCAATAAGATATTGGCCGCACGCGAGGCGCGACAACAGCAGATGGAAAAACTTTATGGCGTTGGACAGGTGGATACGTTGGCTTTGAATACGGGCGCGGGCGGGGATCGTGTGCCTATGCTGGAAGTGCGCCTAGCGCATGCCTCACCCGAGGCTTTTGAGATTATACTTAACTATATCTATACGGATCGCATTGATTTGAAGGACTCGTACAGCAAGAACATTATTATTCTCATTACGGATATCTATCAGTTGGCTGGTCTTTTCACAATGCCACGCCTGGCGCATGGCTGCATTCAGTATCTGGACTATAAgatcaataaaattaatgtgcTCGAGGCGCTCTACAATGCTGACAAGAACAACATCAAAATCATAAAGGATCATTGCATGCAGTTTATTATCAAGGAGGAGAACTTCACCGAAGTGGTTATGTCTAGTGAGTTTAGCGATTTAGACAAACCACTTTTGGTCGAAATAATACGCAAGCGTTTGCATCCCAGCAAGCTGGTAATTGACACTTCCTATGAGTCAAACATTGGCACAACGCTGGAACATGATTTGTCCATGTTTTTGGAAACAACGGGCAAGGACTTTTGCGACATAAGTCTCGTTTTGGATGATCATGTAATACCAGCCCACAAATCTGTGTTATCATCACGTTGTACCTACTTCCAGGGCATGTTTCGATCTTTCATGCCACCGGACAATACCGTTAACATACAAATTGGAGAAATTTCCCCCTCACTGGAAGCCTTCCATTCTCTGTTGCGCTATATATATTATGGAGAGACTAAACTGCCGCCACAGGATGCATTGTACTTGTTTCAAGCACCATGTTTCTACGGATTGTCCAACAATCGTTTGCATGCATTCTGCAAATACTCGTTGGAGCATAATATAACGTCGGAGAATGTGCTGCAGACGCTCGAGGCGTCTGACATAACGAAAATCTATGACATCAAAGattatgcattaaaattaattgtcaAAGATTTTGCCAAAGTGGCCAGGCTGCCCAAAATAGCCGGTTTGTCGCGCGAACTGTTGCTGGAGATCATACGCGCTGTGGCCGATTCGCAAGGCGAGTTTCTTACTCGCATCAATATCAATACAGATATCTGA
Protein Sequence: MLKSILGGDTNDSAEDIPTGGVGGRSARGGSSSGGSGSGGSGRSTNSASAFSRASCGLGSSSISSGLSAVCGRSGSGSGSASASASGSSTPATVYCPACVASSSQQQPEALHQRDSKTGKRQKPRKSASTAGCVDVQHIRNNLSMSTSISTRSTRGSSNSSCSTASASASAMMQCSNGIAYDANSNGSCNSSTFNYKDSPPGSYSYSCNALNVDFNSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFLSAMWVEWKFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENHQWEEVEQQGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYIFGGSADSTLPNDLHCYDLDSQVWSVIQAEQNSDMPSGRVFHASAVIGDAMYVFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFYHEKQFCDIQFVVGAEEIRIQSHIAFVAARSKYLRNKILAAREARQQQMEKLYGVGQVDTLALNTGAGGDRVPMLEVRLAHASPEAFEIILNYIYTDRIDLKDSYSKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKINVLEALYNADKNNIKIIKDHCMQFIIKEENFTEVVMSSEFSDLDKPLLVEIIRKRLHPSKLVIDTSYESNIGTTLEHDLSMFLETTGKDFCDISLVLDDHVIPAHKSVLSSRCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKLPPQDALYLFQAPCFYGLSNNRLHAFCKYSLEHNITSENVLQTLEASDITKIYDIKDYALKLIVKDFAKVARLPKIAGLSRELLLEIIRAVADSQGEFLTRININTDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479535;
90% Identity: iTF_01326474;
80% Identity: -