Datr010176.1
Basic Information
- Insect
- Drosophila atripex
- Gene Symbol
- Lztr1
- Assembly
- GCA_035045925.1
- Location
- JAWNOP010000062.1:470974-474192[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 4.4e-13 1.2e-10 41.6 0.2 1 108 566 707 566 709 0.88 2 4 0.57 1.5e+02 2.6 0.2 78 109 709 740 702 741 0.88 3 4 2.9e-19 7.6e-17 61.5 0.0 8 104 800 898 794 904 0.85 4 4 5.9 1.5e+03 -0.7 0.0 72 100 898 926 892 934 0.83
Sequence Information
- Coding Sequence
- ATGCTAAAGTCGTTCAGTGGCGGCATTGGCGTGGCATCCACGGGAGGAGGCACTGGAAGTGGAGGTGTCGGCAGCGGTGGCGGTGGGGGTGGAGGAACTGGAGGCTctggtggcagtggtggcagtggtggcagtggcggcagcggaggcagtggcggcggcggcggcgggggATCATCAAGGAGTGGGCGTGCCAGTTGTGGTCTGGGCTCCAGTTCCATTTCGAGCGGATTGAGTGCCGTATGCGGTTTTGTGAGAGGCGAGGATCGAGGCACCTCCAGTGGCGGCAGCACACCAGCAGGCGTTATCTATTGCCCCGCCTGTGTGGCAGCCTCTGGCAGTCAGGGCCAGAGCACGAGTCCCGGCCAGAATCCGAGCCCCCACCACGAGTCCTTCTTCTCGCGCAGCTCCTCCAAGTCCAGTAAGCGGCAAAAGGCCAGGAAGAGCGCCTCAACGGCTGGCTGTTTGGACGCCCAGCACATTCGCGCCAATCTGAGAATGTCCACATCGAGTTCTATGCGTAGCACCAGTACCAGGGGCGGTGGAGGTGCCAGTACCAGTGCAGGGGCAGCCGGTAACTATAGCCTGGCGTCGTACGATGCCGCAAGTAAtgccagcagcggcagcggcagtggcagcaccACTGCAGCCTCCCCCGGAAGCTACAGTTGCAACGCATTGAATGTCGATTTTAGCTCCTATACCGCCACCCATCAGTGGACCCGGATGCTGGAGTGTGCCGAGTTTGTGGGTGCCAAACGCAGCAAGCACACCGTGGTGGCCTACAAGGATGCCATGTTTGTGTTCGGCGGCGATAATGGGAAAAACATGCTGAACGATCTGATACGGTTCGGGGTGAAGGACAAGTCGTGGGGCAGGGCGTGTGCCACTGGAACACCACCGGCGCCCCGATACCATCATTCCGCCGTAGTGGCCGGCAGCTCAATGTTCATATTCGGCGGCTATACCGGCGACATTCACTCCAATTCGAATCTGACGAACAAGAATGATCTGTTCGAGTACAAGTTCCAGAGCGCCATGTGGGTGGAGTGGATGTTTTCGGGACGCCAGCCAGTGCCGAGATCGGCCCACGGAGCAGCCGTCTATGATAACAAGATGTGGATCTATGCCGGTTACGATGGCAATGCCAGGCTGAACGATATGTGGACACTGAACCTGACGGGCGAGAATCAGTGGGAGGAGGTGGAACAGCTGGGGGATAGGCCACCGACATGTTGCAACTTTCCGGTTGCGGTGGCCCGGGATGCCATGTACGTATTTTCCGGCCAGAGCGGCCTGCAGATCACCAACTCGCTGTTTGAGTTTCATTTCAAGACGCGCACCTGGCGACGCATCTCCAACGAGCCGGTACTGAGGGGCGCCACATCGGCGCCACCATCCCGCCGATATGGACACACGATGGTCCATCACGATAGGTTCTTGTATGTCTTTGGCGGATCGGCCGACTCGACGCTGCCCAACGATCTGCACTGTTACGATCTGGACTCGCAGGTGTGGTCGGTTATCCAGCCGGAGCAGAACTCGGATGTGCCGTCGGGTCGAGTGTTTCATGCATCGGCCGTGATCGGGGATGCGATGTACATTTTTGGGGGGACGGTGGACAATAGTGTCCGACGGGGGGATACCTATCGGTTTCAGTTCTCCTCGTATCCGAAGTGTACGCTGCGCGATGATTTTGGCAAGTTCTTTTTGGAGAAGCAGTTCTGCGACATCCAGTTCATAGTGGGCGCCGAGGAGGTGCGCATCCTGGCGCACATCGCCTTCGTGGCGGCCCGATCGAAGTATCTGCGCAACAAGATACTGGCGGCGCGAGAGGCGCGCCAGCAGCAGATGGAGAAGGTGTATGGTGTGGGCCAGGTGGATGCCCAGGCGTTGAATACGGGTGCGGGCGGGGACCGCGCCCCCATGCTGGAGGTTCGCCTGGCCCACGCCTCGCCGGAGGCCTTTGACATTATACTCAACTACATATACACGGATCGCATCGATTTGAAGGATTCGTACAACAAGAACATCATCATCCTGATCACGGACATCTATCAATTGGCGGGCTTGTTCACTATGCCGCGGCTGGCCCACGGCTGCATCCAGTATTTGGATTACAAGATCAACAAGCTAAATGTCCTGGAGGCCCTCTACAATGCCGACAAGAGCAACATTAAAATCATCAAGGATCATTGCATGCAGTTCATCATCAAGGACGAGAACTTCACCGATGTGGTCATGTCCAGTGAGTTTAGCGACTTGGACAAGCCACTCTTGGTGGAGATTATCCGGAAGCGACTGCATCCCAGCAAACTGGTGATGGAAACCAGTTTCGAATCGAACACAGGCACCACCCTGGAGATCGATCTGTGCGCCTTCCTCGAGTCAACGGGCAATGACTTCTGCGACATAAGTCTCATTCTGGAGGATCATGTTATACCGGCCCACAAGTCTGTGTTATCATCACGTTGTACCTACTTCCAGGGCATGTTCCGTTCGTTCATGCCCCCGGATAACACCGTCAATataCAAATTGGCGAAATATCACCATCATTGGAGGCATTCCATTCACTTCTGCGATATATCTACTATGGTGAGACGAAGATGCCGCCCCAGGATGCACTGTACCTGTTCCAGGCGCCGTGCTTTTACGGTCTGGCCAATAATCGGCTTCATGCCTTCTGCAAATATTCGCTAGAGCATAATATCAACGATGAGAATGTATTGCAGACGCTGGAGGCGTCGGACATCACCAAAATCTATGACATCAAGGAGTATGCACTCAAGTTGATTGTCAAAGATTTTGCAAAGGTGGCCCGGCTGCCGAAGATAGCGGGTTTGTCGCGCGAACTGTTGCTGGAGATCATATGCGCTGTGGCCGATTCGCACGGCGAGTTTATGACACGGATCAATATCAATACCGATATCTGA
- Protein Sequence
- MLKSFSGGIGVASTGGGTGSGGVGSGGGGGGGTGGSGGSGGSGGSGGSGGSGGGGGGGSSRSGRASCGLGSSSISSGLSAVCGFVRGEDRGTSSGGSTPAGVIYCPACVAASGSQGQSTSPGQNPSPHHESFFSRSSSKSSKRQKARKSASTAGCLDAQHIRANLRMSTSSSMRSTSTRGGGGASTSAGAAGNYSLASYDAASNASSGSGSGSTTAASPGSYSCNALNVDFSSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFQSAMWVEWMFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENQWEEVEQLGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSVIQPEQNSDVPSGRVFHASAVIGDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFLEKQFCDIQFIVGAEEVRILAHIAFVAARSKYLRNKILAAREARQQQMEKVYGVGQVDAQALNTGAGGDRAPMLEVRLAHASPEAFDIILNYIYTDRIDLKDSYNKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKLNVLEALYNADKSNIKIIKDHCMQFIIKDENFTDVVMSSEFSDLDKPLLVEIIRKRLHPSKLVMETSFESNTGTTLEIDLCAFLESTGNDFCDISLILEDHVIPAHKSVLSSRCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKMPPQDALYLFQAPCFYGLANNRLHAFCKYSLEHNINDENVLQTLEASDITKIYDIKEYALKLIVKDFAKVARLPKIAGLSRELLLEIICAVADSHGEFMTRININTDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00479535;
- 90% Identity
- iTF_00566145;
- 80% Identity
- -