Dpar005042.1
Basic Information
- Insect
- Drosophila parabipectinata
- Gene Symbol
- Lztr1
- Assembly
- GCA_018153455.1
- Location
- JAECYA010000021.1:2617811-2620882[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 3.7e-14 9.2e-12 45.0 0.1 1 108 562 693 562 695 0.84 2 4 0.63 1.6e+02 2.4 0.1 78 109 695 726 692 727 0.89 3 4 3.5e-19 8.6e-17 61.2 0.0 8 104 786 884 780 890 0.85 4 4 5.7 1.4e+03 -0.7 0.0 72 100 884 912 880 920 0.83
Sequence Information
- Coding Sequence
- ATGCTAAAGTCGTTCAGTGGCGGCATTGGCGTGGCATCCACGGGAGGAGGCACTGGAAGTGGAGGTGTCGGCAGCGGTGGCGGTGGGGGTGGAGGAACTGGAGGCTCTGGTGGCAGTGGTGGCAGTGGCGGAAGTGGAGGCGGCGGTGGATCATCAAGGAGTGGGCGTGCCAGTTGTGGTCTGGGCTCCAGTTCCATTTCCAGCGGACTGAGTGCCGTTTGCGGTTTTGTGAGAGGCGAGGATCGAGGCACCTCCAGTGGCGGTAGCACACCGGCAGGCGTTATCTATTGTCCCGCCTGTGTGGCAGCATCCGGCAGTCAGGGTCAGAGCACTAGCCCCGGCCAGAATCCGAGCCCCCACCACGAGTCCTTCTTCTCGCGCAGCTCCTCCAAGTCCAGTAAGCGGCAAAAGGCCAGAAAGAGCGCCTCAACGGCAGGCTGTTTGGACGCCCAGCACATTCGCTCCAATCTGAGAATGTCCACCTCGAGTTCCATGCGCAGCACCAGTACCAGGGGCGGCGGAGGCGGAGGTGCCGGCGGTGCCAGTACCAGTGGGGCAGCAGGCAACTCCAGTCTGGCGTCCTACGATGCCGCTAGTAATGCCAGCAGCGGCAGCGGCAGTGGCAGCACCAATGCAGCATCCCCCGGGAGCTACAGTTGCAATGCATTGAACGTTGACTTTAGCTCCTATACGGCCACCCATCAGTGGACCCGGATGCTGGAGTGTGCCGAGTTTGTGGGTGCCAAGCGCAGCAAGCACACTGTGGTGGCCTACAAGGATGCCATGTTTGTGTTCGGCGGCGATAATGGCAAGAACATGCTGAACGATCTGATACGGTTCGGGGTGAAGGACAAGTCGTGGGGCAGGGCGTGTGCCACTGGTACACCACCGGCGCCCCGATACCATCACTCTGCTGTGGTGGCCGGCAGTTCAATGTTCATATTTGGCGGCTATACCGGCGACATACACTCCAATTCGAATCTGACGAATAAGAATGATCTGTTCGAGTACAAGTTCCAGAGCGCCATGTGGGTGGAGTGGATGTTTTCGGGCCGACAGCCGGTGCCGAGATCGGCCCACGGAGCCGCCGTCTATGATAACAAAATGTGGATCTATGCCGGTTACGATGGCAATGCCAGGCTGAACGATATGTGGACGCTGAATCTGACGGGCGAGAATCAGTGGGAGGAGGTGGAACAGCTGGGGGACAGGCCACCGACATGTTGCAACTTTCCGGTTGCGGTGGCCCGGGATGCCATGTATGTATTTTCCGGCCAGAGCGGCCTGCAGATCACCAACTCGCTGTTTGAGTTTCATTTCAAGACGCGCACCTGGCGACGCATCTCCAATGAGCCGGTGCTGAGGGGCGCCACATCGGCGCCGCCATCCCGCCGTTACGGACACACGATGGTGCATCACGATCGATTCCTGTATGTCTTTGGCGGATCGGCGGATTCGACGCTGCCCAACGATCTCCACTGCTACGATCTGGACTCGCAGGTCTGGTCGGTTATCCAGCCGGAGCAGAACTCGGATGTGCCGTCGGGTCGAGTGTTTCACGCCTCGGCCGTGATCGGTGATGCGATGTACATATTTGGGGGAACGGTGGACAATAGTGTGCGACGGGGGGACACCTATCGGTTTCAGTTCTCCTCGTATCCGAAGTGCACGCTGCGCGATGATTTCGGCAAGTTCTTTTTGGAGAAGCAGTTCTGCGACATCCAGTTCATAGTCGGGGCCGAGGAGGTGCGCATCCTGGCGCACATCGCCTTTGTGGCCGCCCGATCCAAGTATCTGCGCAACAAGATCCTGGCGGCGCGAGTGGCTCTCGAACAGCAGTTACCGTTGGAGTTCTATACGCCTTCGGGCGGAGACCGTTCACCCATGTTGGAGGTTCGCCTGGCACACGCCTCGCCGGAGGCCTTTGACATCATCCTCAACTACATATATACGGATCGGATCGATTTAAAGGATTCGTATAACAAGAACATCATCATTCTGATAACGGACATCTATCAATTGGCGGGGTTGTTCACCATGCCGCGGCTGGCCCACGGCTGTATCCAGTATTTGGATTACAAGATCAACAAGCTGAATGTCCTGGAGGCACTCTACAATGCCGACAAGAGCAATATTAAAATCATCAAGGATCATTGCATGCAGTTCATCATCAAGGACGAGAACTTCACCGACGTGGTCATGTCCAGTGAGTTTAGTGATTTGGACAAGCCACTCCTGGTGGAGATCATCCGGAAGCGTTTGCATCCCAGCAAGCTGGTAATGGAAACCAGTTTCGAGTCAAACACTGGCACTACCCTGGAGATCGATCTGTGCGCCTTCCTGGAGACGACGGGCAGTGATTTTTGTGACATTAGCCTCATACTGGAGGACCATGTTATTCCGGCCCACAAATCTGTGTTATCATCACGTTGTACCTACTTCCAGGGCATGTTCCGTTCGTTCATGCCCCCGGATAATACCGTCAATATACAAATTGGCGAAATATCACCATCATTGGAGGCATTCCATTCGCTATTGCGTTATATCTACTATGGTGAGACTAAGATGCCGCCCCAGGATGCACTGTATCTGTTCCAGGCGCCGTGCTTTTATGGTTTGGCCAATAATCGGTTACATGCCTTCTGCAAATATTCACTGGAGCATAATATCAACGATGAGAATGTATTGCAAACGCTGGAGGCATCGGACATCACCAAAATCTATGACATCAAGGAGTATGCCCTCAAGTTGATTGTCAAAGATTTTGCCAAGGTGGCCCGATTGCCGAAGATAGCGGGTTTGTCGCGCGAACTGTTGCTGGAGATCATATGCGCTGTGGCCGATTCGCACGGCGAGTTTATGACAAGGATCAATATCAATACCGATATCTGA
- Protein Sequence
- MLKSFSGGIGVASTGGGTGSGGVGSGGGGGGGTGGSGGSGGSGGSGGGGGSSRSGRASCGLGSSSISSGLSAVCGFVRGEDRGTSSGGSTPAGVIYCPACVAASGSQGQSTSPGQNPSPHHESFFSRSSSKSSKRQKARKSASTAGCLDAQHIRSNLRMSTSSSMRSTSTRGGGGGGAGGASTSGAAGNSSLASYDAASNASSGSGSGSTNAASPGSYSCNALNVDFSSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFQSAMWVEWMFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENQWEEVEQLGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSVIQPEQNSDVPSGRVFHASAVIGDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFLEKQFCDIQFIVGAEEVRILAHIAFVAARSKYLRNKILAARVALEQQLPLEFYTPSGGDRSPMLEVRLAHASPEAFDIILNYIYTDRIDLKDSYNKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKLNVLEALYNADKSNIKIIKDHCMQFIIKDENFTDVVMSSEFSDLDKPLLVEIIRKRLHPSKLVMETSFESNTGTTLEIDLCAFLETTGSDFCDISLILEDHVIPAHKSVLSSRCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKMPPQDALYLFQAPCFYGLANNRLHAFCKYSLEHNINDENVLQTLEASDITKIYDIKEYALKLIVKDFAKVARLPKIAGLSRELLLEIICAVADSHGEFMTRININTDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00479535;
- 90% Identity
- iTF_00488074; iTF_00539018; iTF_00580032; iTF_00615620; iTF_00546021; iTF_00504047; iTF_00614961; iTF_00475987; iTF_00477388; iTF_00550303; iTF_00481594;
- 80% Identity
- -