Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: Lztr1
Assembly: GCA_037043435.1
Location: JBAMBK010002349.1:120256-124925[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.7e-13 3.8e-11 43.4 0.4 1 108 583 724 583 726 0.87

2 3 0.34 76 3.8 0.1 77 109 725 757 721 758 0.90

3 3 1e-19 2.3e-17 63.4 0.0 8 97 817 906 811 921 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.7e-13	3.8e-11	43.4	0.4	1	108	583	724	583	726	0.87
2	3	0.34	76	3.8	0.1	77	109	725	757	721	758	0.90
3	3	1e-19	2.3e-17	63.4	0.0	8	97	817	906	811	921	0.85

Sequence Information

Coding Sequence: ATGCTAAAATCGATACTTGGCGCAGACACGAATGGTTCTGCGGAAGATCTACCAAGCGgaggcgttggcgttggcgtcgcCAGCGGCAGTAGTGgaggcagcggcagtggcagtggcaacggcagcgccagcggcagtggcagcaCCAGCTGTACTGGAGCACTTAGCCGAGCCAGTTGCGGCCTGGGTTCCAGTTCCATTTCCAGTGGCTTAAGTGCTGTCTGTGGCCTAGTCTCAAGTGgtagtggcagtggcagtggcagtgggaGTGGCAGTCAAAGTGCTAGTGCAAGTGGTGGCAGTACACCAGCAACCGTTTATTGCCCTGCATGCGTAGCCAACAGTACGTCGCTGCATCAGCAACTGGCATTTGCCGCTGGTGCTGAGGCATTATTGCTAACGCGAGACTCGAAATCGGGCAAGAGACCAAAGGCGCGCAAAAGTGCATCTTCTGTTGGCTGCCTGGACGCGCAGCATATACGCAATAATCTTAAAAAGTCCACATCAAGCTCAATGCGCAGTACTCGGGCATCTGGCGGTGCTGCCGCCGTCGGCGCTGGCGCTGGCGCTGgtagtagcagcagcagcagcactgcCTCGGCCGTCATTCCATGCGCAGCTGCATCCAGCGGTTGCAGCAGCCTGGCCTACGATGGCATCAGCAATGGCAGCTGCAGCAGTGGCAATGGCAAGGTCAACTCACCCGGCAGCTACAGCTGCAATGCCCTCAACGTTGACTTCAGCTCCTACACGGCAACACACCAATGGACACGCATGCTGGAATGTGCCGAATTCGTGGGCGCCAAGCGGAGCAAGCACACGGTGGTTGCCTACAAGGATGCCATGTTCGTGTTTGGCGGCGACAATGGCAAGAACATGCTCAACGATCTGATACGATTTGGCGTCAAGGACAAGTCCTGGGGCAGAGCTTGTGCCACGGGCACACCGCCAGCGCCACGCTATCACCATTCAGCGGTTGTGGCAGGCAGTTCAATGTTCATATTTGGCGGTTACACCGGCGACATACACTCAAACTCAAATCTGACCAATAAGAATGATTTGTTCGAGTATAAATTCCTCAGCGCCATGTGGGTGGAGTGGAAGTTTTCGGGCAGACAACCTGTGCCACGATCGGCACATGGCGCCGCTGTTTATGACAACAAAATGTGGATTTATGCTGGCTACGATGGCAATGCTCGTTTAAATGACATGTGGACGTTAAATTTGACCGGCGAGAATCATAATTGGGAGGAGGTGGAACAGCGTGGTGATCGTCCGCCCACCTGTTGCAATTTCCCAGTTGCCGTTGCCCGAGACGCCATGTATGTGTTCTCTGGCCAGAGCGGATTGCAGATAACAAATTCGCTATTTGAGTTTCACTTCAAGACACGAACCTGGCGTCGGATTTCCAATGAGCCGGTGTTGCGTGGTGCCACATCGGCGCCACCATCACGTCGCTATGGCCATACAATGGTCCATCATGATCGATTTTTGTATGTGTTTGGCGGATCGGCAGACTCGACGCTGCCAAATGATTTGCATTGTTATGATCTGGACTCGCAGGTGTGGTCCATTATACACCCGGAACAGAATTCGGATGTGCCGTCGGGTCGGGTGTTTCATGCCTCGGCCGTAATTAGCGATGCCATGTACATCTTTGGTGGCACCGTCGACAACAGTGTGCGACGCGGCGATACCTATCGCTTTCAATTCTCCAGCTATCCGAAATGTACGCTGCGcgatgattttggcaaatTCTTCCACGAGAAGCAATTCTGCGATATCCAGTTTGCAGTGGGCGTGGAGGAGATACGAATCTTGGCGCACATTGCCTTTGTTGCGGCACGCTCCAAGTATTTGCGCAACAAGATTCTATCGGCACGCGAGGCGCGTCAGCAGCAGATGGAAAAGGTCTATGGCGTTGGTCAGGTGGATGCACAGGCATTGAATACAGGCGTCGGTGCGGATCGAGCACCCATGCTGGAGGTGCGACTGGCCCATGCCTCGCCAGAGGCATTCGAGATCATCCTTAACTACATCTATACGGATCGCATTGATTTAAAGGATTCATACAGCAAGAACATAATCATTCTGATCACGGACATTTATCAACTGGCCGGACTGTTTACAATGCCACGCCTGGCGCACGGATGCATTCAGTATCTGGACTATAAGATCAACAAAGGGAATGTTCTCGAGGCGCTCTACAATGCGGATAAAAGCAACATTAAAATCATCAAGGATCATTGCATGCAGTTCATCATTAAGGATGAGAATTTCGACGATGTGGTCATGTCCAGTGAGTTTAGTGATCTCGATAAGCCGCTGCTGGTCGAGATAATACGCAAACGCTTGCATCCCAGCAAGTTGGTCATGGAAACCAGTTTTGAGTCCAATATTGGTACCACTTTGGAGATTGATTTGTCCACATTTTTGGAGACAACAGGCAAGGACTTTTGCGATATAAGCCTCATACTGGAGGATCATGTGATACCGGCCCACAAGTCTGTGTTATCAGCACGTTGTACCTATTTCCAGGGCATGTTTCGTTCGTTCATGCCACCGGATAATACCGTTAATATACAAATTGGCGAAATTTCACCTTCACTGGAGGCCTTCCATTCGTTGCTACGCTACATTTATTATGGAGAGACCAAGATGCCACCACAGGATGCACTGTATCTATTTCAGGCGCCCTGTTTTTATGGTCTATCGAACAATCGTTTGCATGCATTCTGCAAATATTCACTGGAGCATAACATTACGTATGAGAATGTATTGCAGACGCTGGAAGCGTCcgatataacaaaaatttatgacaTCAAAGAATATgcattgaaattaattgtGAAAGATTTTGCCAAGGTCGCCAGGCTACCAAAAATCGGTGGCTTGTCGCGCGAACTGTTGCTGGAGATAATACGCGCTGTGGCCGATTCGCAAGGCGAGTTTCTGACCCGCATCAATATCAATACCGATATCTGA
Protein Sequence: MLKSILGADTNGSAEDLPSGGVGVGVASGSSGGSGSGSGNGSASGSGSTSCTGALSRASCGLGSSSISSGLSAVCGLVSSGSGSGSGSGSGSQSASASGGSTPATVYCPACVANSTSLHQQLAFAAGAEALLLTRDSKSGKRPKARKSASSVGCLDAQHIRNNLKKSTSSSMRSTRASGGAAAVGAGAGAGSSSSSSTASAVIPCAAASSGCSSLAYDGISNGSCSSGNGKVNSPGSYSCNALNVDFSSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFLSAMWVEWKFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENHNWEEVEQRGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSIIHPEQNSDVPSGRVFHASAVISDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFHEKQFCDIQFAVGVEEIRILAHIAFVAARSKYLRNKILSAREARQQQMEKVYGVGQVDAQALNTGVGADRAPMLEVRLAHASPEAFEIILNYIYTDRIDLKDSYSKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKGNVLEALYNADKSNIKIIKDHCMQFIIKDENFDDVVMSSEFSDLDKPLLVEIIRKRLHPSKLVMETSFESNIGTTLEIDLSTFLETTGKDFCDISLILEDHVIPAHKSVLSARCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKMPPQDALYLFQAPCFYGLSNNRLHAFCKYSLEHNITYENVLQTLEASDITKIYDIKEYALKLIVKDFAKVARLPKIGGLSRELLLEIIRAVADSQGEFLTRININTDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479535;
90% Identity: iTF_00537579;
80% Identity: -