Dpul002415.1
Basic Information
- Insect
- Drosophila pullipes
- Gene Symbol
- Lztr1
- Assembly
- GCA_035043795.1
- Location
- JAWNMT010000138.1:121436-125238[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 5.2e-13 1.2e-10 41.4 0.3 2 108 531 671 530 673 0.87 2 4 0.38 88 3.2 0.1 77 108 672 703 668 705 0.89 3 4 4e-19 9.1e-17 61.1 0.0 8 97 764 853 758 868 0.85 4 4 7.6 1.8e+03 -1.0 0.0 72 100 862 890 856 898 0.83
Sequence Information
- Coding Sequence
- ATGCTAAAGTCCATACTCGGTGGGGACACGAATGGTTCTGCGGAAGATATACCAACTGGAGGCGTGTGCGGCGggagtggcagtggcagcggtcGAAGCACCAACGGTGCTGCAGCATTTAGCCGAGCCAGTTGCGGCTTGGGCTCCAGCTCGATATACAGTGGCCTAAGTGCTgtgtgtggcagtggcagtggcagactGAGTGGAAGCGGAAGTGCAAGTGCAAGTGCGAGTGGCAGTGGGAGCAGTACACCAGCAACCGTTTATTGCCCTGCATGCGTAGCCAGCAgctcacagcaacagcagcagcagtcgcagccgcagcagcagcagtcgcagccgcagcagcagcagacagacGCATTCCTTCAGCGAGATTCGAAGTCGGGCAAGAGGGCAAAGGGACGCAAAAGTGCATCGACAGCTGGCTGCGTTGACGTGCAGCATATACGCAACAATCTGAGCATGTCCACATCGAGCTCAACGCGCAGCACacgcggcggcagcaacagcagctgcagcactgCCTCAAACTCACCGggcagctacagctacagctgcaaTGCCCTCAACGTCGACTTCAATTCCTATACGGCAACACATCAGTGGACGCGCATGCTCGAATGTGCTGAGTTTGTTGGCGCCAAACGCAGTAAGCATACGGTGGTTGCCTACAAGGATGCCATGTTCGTGTTTGGCGGCGATAATGGCAAGAACATGCTCAACGACCTGATACGCTTTGGTGTCAAGGACAAGTCATGGGGACGGGCATGTGCAACTGGAACGCCACCGGCGCCGCGCTATCATCATTCCGCTGTTGTTGCGGGCAGCTCGATGTTTATATTTGGCGGCTATACGGGCGACATTCACTCCAACTCCAATCTGACCAACAAGAATGATTTGTTTGAGTACAAGTTTCTTAGCGCCATGTGGGTGGAGTGGAAATTCTCGGGCAGGCAACCAGTGCCGCGTTCGGCGCATGGTGCAGCGGTTTACGACAACAAGATGTGGATTTACGCCGGCTATGATGGCAATGCTCGGCTTAACGATATGTGGACGCTGAATTTAACGGGCGAGAATCATCAATGGGAGGAGGTAGAACAGCAGGGCGATCGTCCGCCCACCTGTTGTAATTTCCCCGTTGCCGTTGCACGCGATGCCATGTATGTGTTCTCCGGCCAGAGTGGTCTCCAGATAACAAATTCGCTGTTTGAGTTTCACTTTAAGACGCGCACATGGCGTCGCATTTCCAATGAGCCGGTGCTGCGTGGCGCTACATCGGCACCACCGTCGCGTCGCTATGGCCACACCATGGTCCATCACGATCGCTTCCTGTATATTTTTGGAGGTTCAGCTGACTCGACGCTGCCAAATGATTTACACTGTTATGATCTTGACTCACAGGTGTGGTCCGTCATTCAGGCGGAGCAGAACTCGGATATGCCGTCGGGTCGCGTATTCCATGCATCCGCCGTCATTGGCGATGCGATGTACATATTTGGCGGCACCGTCGACAATAGCGTACGGCGCGGAGATACGTATCGGTTTCAGTTCTCCAGCTATCCAAAGTGCACACTACGTGACGACTTTGGCAAATTCTATCACGAGAAGCAATTCTGTGATATTCAGTTTGTGGTGGGCGCCGAAGAGATACGCATTCTTTCGCACATTGCCTTCGTAGCGGCACGCTCTAAATATTTGCGTAACAAGATATTGTCAGCGCGCGAGGCGCGTCAACAACAGATGGAGAAGCTCTATGGTGTTGGGCAAGTGGATACGCTGGCTTTGAATACGGGCGTCGGCGGGGATCGCGTGCCGATGCTGGAGGTGCGATTGGCACATGCCTCACCCGAGGCATTTGAGATAATACTTAACTATATCTATACGGATCGCATTGACCTGAAGGACTCATACAGCAAGAATATCATCATTCTCATCACGGACATCTATCAATTGGCTGGTCTGTTCACTATGCCGCGCCTAGCGCACGGCTGCATCCAGTACCTGGATTATAagatcaacaaaataaatgtgctgGAGGCTCTTTACAATGCTGACAAAAACAACATTAAAATCATCAAGGATCATTGCATGCAGTTCATCATCAAGGAAGAGAACTTCACCGAAGTGGTCATGTCCAGTGAGTTCAGTGATCTGGACAAGCCACTGCTGGTCGAGATAATACGTAAGCGTTTGCATCCGAGCAAGCTGGTGATAGACACTACTTATGAATCGAATATTGGCACTACGCTGGAGCACGATTTGTCCATGTTCTTGGAGACAACGGGCAAGGACTTTTGCGATATAAGTCTAATACTAGAGGATCATGTGATACCAGCTCACAAATCTGTGTTATCGTCACGTTGTACCTATTTCCAGGGCATGTTCCGCTCGTTCATGCCACCGGATAATACTGTTAATATACAAATTGGCGAAATCTCACCCTCACTAGAGGCCTTTGATTCGCTGCTacgctatatatattatggggAGACAAAGATGCCGCCACAGGATGCATTATACCTGTTCCAGGCACCCTGTTTCTATGGTTTGTCCAACAATCGGTTGCACGCATTCTGCAAATACTCATTGGAACATAACATTACGTCGGAGAATGTGCTGCAGACGCTGAAGGCGTCCGACATAACAAAAATCTATGACATCAAGGATTatgcattgaaattgattgtGAAAGATTTTGCTAAAGTTGCCAGGCTGCCCAAAATAGCCGGTTTGTCGCGCGAACTGTTGCTGGAGATAATACGCGCTGTGGCCGATTCGCAAGGCGAGTTTCTGACCCGAATCAATATCAATACTGATATCTGA
- Protein Sequence
- MLKSILGGDTNGSAEDIPTGGVCGGSGSGSGRSTNGAAAFSRASCGLGSSSIYSGLSAVCGSGSGRLSGSGSASASASGSGSSTPATVYCPACVASSSQQQQQQSQPQQQQSQPQQQQTDAFLQRDSKSGKRAKGRKSASTAGCVDVQHIRNNLSMSTSSSTRSTRGGSNSSCSTASNSPGSYSYSCNALNVDFNSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFLSAMWVEWKFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENHQWEEVEQQGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYIFGGSADSTLPNDLHCYDLDSQVWSVIQAEQNSDMPSGRVFHASAVIGDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFYHEKQFCDIQFVVGAEEIRILSHIAFVAARSKYLRNKILSAREARQQQMEKLYGVGQVDTLALNTGVGGDRVPMLEVRLAHASPEAFEIILNYIYTDRIDLKDSYSKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKINVLEALYNADKNNIKIIKDHCMQFIIKEENFTEVVMSSEFSDLDKPLLVEIIRKRLHPSKLVIDTTYESNIGTTLEHDLSMFLETTGKDFCDISLILEDHVIPAHKSVLSSRCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFDSLLRYIYYGETKMPPQDALYLFQAPCFYGLSNNRLHAFCKYSLEHNITSENVLQTLKASDITKIYDIKDYALKLIVKDFAKVARLPKIAGLSRELLLEIIRAVADSQGEFLTRININTDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00479535;
- 90% Identity
- -
- 80% Identity
- -