Basic Information

Insect: Meganola albula
Gene Symbol: e2f7
Assembly: GCA_936440415.1
Location: CAKZFH010000018.1:2055940-2057327[+]

Transcription Factor Domain

TF Family: E2F
Domain: E2F_TDP domain
PFAM: PF02319
TF Group: Helix-turn-helix
Description: This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 8.5e-23 3.2e-19 68.5 0.0 1 65 53 118 53 118 0.94

2 3 2.3 8.7e+03 -3.4 0.0 11 29 124 141 123 142 0.69

3 3 5.2e-17 2e-13 49.9 0.1 1 64 153 243 153 244 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	8.5e-23	3.2e-19	68.5	0.0	1	65	53	118	53	118	0.94
2	3	2.3	8.7e+03	-3.4	0.0	11	29	124	141	123	142	0.69
3	3	5.2e-17	2e-13	49.9	0.1	1	64	153	243	153	244	0.90

Sequence Information

Coding Sequence: ATGTATGAAGATGACAACTTAACTTGTACTCCGAAACGCTGTGTTCTCACAGAAGTTACAAATTCGGCTAACTATGTGTCACCAACAGCTAACCTTAAGCTTCTGACGAATGTTGCGCTGCAATACCCGACTCCGCCACCCAGTGCTGTTCATCGAAAAGAAAAATCTCTTCAAATATTGTGTGACAGATTCCTTCATTTATATCCTCTTCATGGAGCTCCAGAGGAAATACAGTTGGATAGCACTGCAGCCAGGCTAGGCGTTGAGAAGCGTCGAATGTATGACATTATCAACATATTAGAAGCTATGCAGTGTGCAGTTCACAAAAGGAAAAACACTTATCTGTGGCATGGAGGATCTAGATTAAATTCATTTCTAAAAATGCTAAAGAAACAGGGAGAGCACCTGAGGCTCTCGGAAGCACTACGAGGAAAAGCACCAAAGCCTCCAGCTCCAAAACATAAAACATTGGGAGTTTTAGCACAAAGATTCTTGATGCTTTTCTTAGTTGAACCtcctAATACTCTTATTAACCTTGAGATGGCTGTCAGAGTGCTGATTGACACTTCAAACAAATCCAAAACACTCCTCTCTCCAGAGCAACAGGATCGGCAACATAAGTCAAAAGTTAGACGGCTGTATGACATTGCTAATGTTTTTATTTCAATTGGTCTCATTGAGAAAGTGTCAGGAAATTTGATATTAAAAAAGCCAGTTTTTAAATATGTGGGTCCCTTCAAGATGAAAAAGTGTGACAAAACATTGACTACTCCATCTCCAATTACACCGTTGACAGTGCTAGATAGCCAACAAAGGGCTTCCACTTGCCATGTGTATGCTGGACGGTCAAAACGGAAATTGGAGTTCACCACTCCCACTTCCAATAAAGAACTAAAGCTTGGTATCACAACCCCACCTCACACTCCGTCTCACAAATGGGATGAAATCCTACTTGTAGCAGACATGGAACTGACTAGGATTAACAATGGAGTAGCCTTGTGA
Protein Sequence: MYEDDNLTCTPKRCVLTEVTNSANYVSPTANLKLLTNVALQYPTPPPSAVHRKEKSLQILCDRFLHLYPLHGAPEEIQLDSTAARLGVEKRRMYDIINILEAMQCAVHKRKNTYLWHGGSRLNSFLKMLKKQGEHLRLSEALRGKAPKPPAPKHKTLGVLAQRFLMLFLVEPPNTLINLEMAVRVLIDTSNKSKTLLSPEQQDRQHKSKVRRLYDIANVFISIGLIEKVSGNLILKKPVFKYVGPFKMKKCDKTLTTPSPITPLTVLDSQQRASTCHVYAGRSKRKLEFTTPTSNKELKLGITTPPHTPSHKWDEILLVADMELTRINNGVAL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01338277; iTF_00071201; iTF_00121185; iTF_01094690; iTF_00123140; iTF_01093828; iTF_01339748; iTF_00745417; iTF_00667146; iTF_00757930; iTF_01532818; iTF_00120279; iTF_01092856; iTF_00124026; iTF_01246618; iTF_00924380; iTF_00017969; iTF_01487505; iTF_00383410; iTF_00782433; iTF_01181697; iTF_00695269; iTF_00777797; iTF_00775849; iTF_00457805; iTF_00457038; iTF_00779311; iTF_00781616; iTF_00775057; iTF_00777234; iTF_00621014; iTF_00778585; iTF_00780058; iTF_01077980; iTF_00776573; iTF_00985789; iTF_00774303; iTF_00780832; iTF_00276063; iTF_00795490; iTF_01438689; iTF_00887214; iTF_00971024; iTF_00166740; iTF_01082228; iTF_00970199; iTF_01437759; iTF_00858338; iTF_00150275; iTF_01176003; iTF_01138756; iTF_00249509; iTF_00197167; iTF_01129847; iTF_01141444; iTF_01145094; iTF_01143657; iTF_01147216; iTF_01149366; iTF_01142205; iTF_01144350; iTF_01148628; iTF_00957754; iTF_00432925; iTF_00431922; iTF_01147901; iTF_01140734; iTF_00009796; iTF_00022594; iTF_00660099; iTF_00658151; iTF_00656936; iTF_01463048; iTF_00289417; iTF_00411210; iTF_00654026; iTF_01133514; iTF_00655886; iTF_01072239; iTF_00149168; iTF_00871089; iTF_00462163; iTF_00008692; iTF_00409078; iTF_00148279; iTF_00410071; iTF_00659257; iTF_00412314; iTF_00772668; iTF_01245726; iTF_00156045; iTF_00325162; iTF_00021131; iTF_01134575; iTF_00342006; iTF_01135544; iTF_00155103; iTF_01463953; iTF_00680311; iTF_01222276; iTF_01546436; iTF_01543693; iTF_01545553; iTF_01560923; iTF_01542749; iTF_01544672; iTF_00159621; iTF_00722831; iTF_00896565; iTF_00247834; iTF_00246975; iTF_00673285; iTF_00931014; iTF_01221284; iTF_00185929; iTF_00185100; iTF_00726075; iTF_01362884; iTF_00888005; iTF_01025765; iTF_01030923; iTF_01029007; iTF_01027089; iTF_00869414; iTF_00282058; iTF_01151852; iTF_01332334; iTF_01491668; iTF_00888982; iTF_00280921; iTF_00909542; iTF_00708967; iTF_01084039; iTF_01443623; iTF_00406501; iTF_00043272; iTF_01531754; iTF_00444899; iTF_00425163; iTF_01377261; iTF_01489933; iTF_00932209; iTF_00017134; iTF_00783216; iTF_00785808; iTF_00784186; iTF_00784991; iTF_01062544; iTF_00122145; iTF_00685220; iTF_00172519; iTF_01061671; iTF_01064424; iTF_01063539; iTF_00711604; iTF_01259871; iTF_00072050; iTF_00317906; iTF_00994162; iTF_01028051; iTF_00038486; iTF_01285335; iTF_01230300; iTF_01361372; iTF_00300959; iTF_00036413; iTF_01119069; iTF_00111390; iTF_01118048; iTF_00037566; iTF_00274238; iTF_01425758; iTF_01533726; iTF_00147090; iTF_00794111; iTF_01029947; iTF_00039584; iTF_00928448; iTF_01116960; iTF_00808893; iTF_00358311; iTF_00710829; iTF_01561812; iTF_00709975; iTF_00357213; iTF_01193406; iTF_01217287; iTF_00934530; iTF_01247879; iTF_00933516; iTF_00744398; iTF_00164115; iTF_01178196; iTF_00405721; iTF_01018370; iTF_01151015; iTF_01017530; iTF_01079686; iTF_01506958; iTF_01507857; iTF_00942601; iTF_01080522; iTF_01078866; iTF_00824499; iTF_01506131; iTF_01020983; iTF_00642136; iTF_00954201; iTF_00843294; iTF_00786560; iTF_00925524; iTF_00842440; iTF_00895713; iTF_00958498; iTF_00461348; iTF_00959204; iTF_01033512; iTF_01034324; iTF_00959960; iTF_00345609; iTF_01435850; iTF_00404483; iTF_00823716; iTF_00448808; iTF_00363817; iTF_01197513; iTF_01360399; iTF_00706737; iTF_01166385; iTF_00637266; iTF_01501877; iTF_00822678; iTF_00441274; iTF_00908603; iTF_00636062; iTF_00156991; iTF_00875945; iTF_00874245; iTF_00875097; iTF_00063371; iTF_00341129; iTF_00947692; iTF_01158508; iTF_00204165; iTF_01153646; iTF_01156078; iTF_01157460; iTF_01154809; iTF_01337565; iTF_00821567; iTF_00723760; iTF_00467985; iTF_00723761; iTF_00467251; iTF_00194972; iTF_00000973; iTF_00000107; iTF_00025069; iTF_00026637; iTF_00027553; iTF_00647789; iTF_00835341; iTF_00837260; iTF_00834418; iTF_00836310; iTF_00648901; iTF_00250252; iTF_00649817; iTF_00926383; iTF_00913402; iTF_00390171; iTF_00701748; iTF_00186934; iTF_00055192; iTF_00205853; iTF_00277167; iTF_01010159; iTF_00770896; iTF_00878660; iTF_01206346; iTF_00430411; iTF_00427887; iTF_00819849; iTF_00428792; iTF_00818941; iTF_01429725; iTF_01204663; iTF_00114731; iTF_01205495; iTF_01202265; iTF_01203834; iTF_01203037; iTF_01316112; iTF_00113129; iTF_00790033; iTF_01401073; iTF_00323282; iTF_00621811; iTF_01173064; iTF_01073397; iTF_01180118; iTF_01179294; iTF_00256643; iTF_00144361; iTF_00255607; iTF_00761416; iTF_01436808; iTF_01416562; iTF_01251543; iTF_00006874; iTF_01415613; iTF_01317071; iTF_01083090; iTF_00204924; iTF_00796316; iTF_00953310; iTF_00677332; iTF_00859252; iTF_01358680; iTF_01358681; iTF_01359508; iTF_00287852; iTF_00012725; iTF_00832694; iTF_01547319; iTF_00236440; iTF_00235664; iTF_00449912; iTF_00622602; iTF_00213209; iTF_00984820; iTF_00212218; iTF_00290457; iTF_00787413; iTF_00162298; iTF_00161348; iTF_00736413; iTF_00007800; iTF_00827773; iTF_00077281; iTF_01403235; iTF_00207656; iTF_00208622; iTF_00844108; iTF_00355918; iTF_01090479; iTF_00354880; iTF_00124958; iTF_00206787; iTF_01208996; iTF_00142885; iTF_00818151; iTF_00033613; iTF_00935475; iTF_00826616; iTF_00634105; iTF_01172121; iTF_00032699; iTF_00044251; iTF_00666301; iTF_01207903; iTF_00825376; iTF_00719998; iTF_00651521; iTF_00640072; iTF_00146188; iTF_00011732; iTF_01220446; iTF_00072512; iTF_01091486; iTF_00801594; iTF_00418761; iTF_00420338; iTF_00421141; iTF_00419577; iTF_00790990; iTF_01264190; iTF_01076177; iTF_01509374; iTF_00119400; iTF_00041569; iTF_00176897; iTF_00301890; iTF_00299939; iTF_00373699; iTF_00810788; iTF_01424836; iTF_01439684; iTF_00696293; iTF_00704742; iTF_00973511; iTF_01528071; iTF_00040584; iTF_00237256; iTF_01335720; iTF_00856393; iTF_00632554; iTF_00638442; iTF_00662026; iTF_01428842; iTF_00445899; iTF_00830955; iTF_01440779; iTF_00321388; iTF_00698061; iTF_00661070; iTF_00905902; iTF_00850383; iTF_00952495; iTF_00737264; iTF_00686129; iTF_00703729; iTF_00705777; iTF_00771665; iTF_00699890; iTF_00374963; iTF_00806483; iTF_00851508; iTF_00907668; iTF_01161108; iTF_00042422; iTF_00674103; iTF_01099671; iTF_01171255; iTF_01526807; iTF_01534583; iTF_00809848; iTF_01170360; iTF_01219576; iTF_01525720; iTF_00049689; iTF_00273401; iTF_00698969; iTF_01342009; iTF_00446906; iTF_00700794; iTF_00702683; iTF_00171548; iTF_00361404; iTF_01075164; iTF_01528988; iTF_00376893; iTF_00662877; iTF_00697117; iTF_01192413; iTF_00407358; iTF_01182462; iTF_00951583; iTF_01084927; iTF_00266976; iTF_00906848; iTF_01564350; iTF_00275039; iTF_00177870; iTF_00352831; iTF_00353870; iTF_01302080;
90% Identity: iTF_00931014;
80% Identity: -