Tsen003360.1
Basic Information
- Insect
- Thumatha senex
- Gene Symbol
- e2f7
- Assembly
- GCA_948477245.1
- Location
- OX419726.1:22221614-22222781[+]
Transcription Factor Domain
- TF Family
- E2F
- Domain
- E2F_TDP domain
- PFAM
- PF02319
- TF Group
- Helix-turn-helix
- Description
- This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 3.4e-22 3e-18 66.3 0.0 1 65 54 120 54 120 0.92 2 3 0.91 8.1e+03 -2.4 0.0 11 29 126 143 125 145 0.75 3 3 8.6e-17 7.7e-13 48.9 0.1 3 64 157 245 155 246 0.90
Sequence Information
- Coding Sequence
- ATGATGTATGAAGATGACAACATAACTTCTACACCAAAGCGCTGCGTGCTGACTGAAGTCACGAATTCAACGAACTATGTGTCGCCCACTGCTAACCTCAAATTGCTAACTAATGTGGCGCTGCAGTATCCCACTCCGCCGCCAAGTGCTGTTCAAAGAAAAGAAAAATCCCTCCAAATACTATGTGATAGATTCCTCAATATGTATCCTCTGCATGGAGATGGCCCAATCGAAATCCAACTGGATAGCACTGCGACCAGGCTAGGTGTGGAAAAACGTAGAATGTATGACATAATCAATATACTAGAAGCTATGCAGTGTGCAGTTCATAAAAGAAAGAACACATATCTCTGGCATGGAGGATCTAGATTAAATTCATTTTTGAAGATGCTTAAAAAGCAAGGAGAACATCTTAAGCTGTCAGAGGCATTACGTGGAAAGGCACCTAAGCCTCCTGCTCCAAAATATAAAACTCTTGGTGTTTTGGCTCAGAGATTCCTTATGCTATTTTTAGTAGAACCTCCTAATACTCTTATAAATCTGGAGATGGCTGTGAGAGTACTGATAGACACATCTAGTAAGACTAAAACTGTGCTCTCCCCAGAGCAGCAGGACCGTCAGCACAAATCTAAAGTAAGAAGACTGTATGATATTGCCAATGTATTTATTTCTATTGGTCTCATTGAAAAAGTATCTGGTAATTTAATATTAAAAAAACCAGTGTTTAAATATGTGGGACCACATAATATTAAAAAGTATGACAAAACATGTCTAAATACTCCATCACCTATTACACCGCTTTCGGCTTTAGACAACCAACAGCGGATACCTTCCTGTCATGTGTTTACTGGTAGGTCTAAACGGAAACTGGAGTTTACAACACCACTTTCCACCAAAGAACTGAAGCTTGGTATCACAACCCCACCTCATACACCGTCGTATAAGTGGGATGAGATCTTACTTGTTGCCGACATGGAACTGACTAAAATTAACAATGGGGTAGTCTTGTGA
- Protein Sequence
- MMYEDDNITSTPKRCVLTEVTNSTNYVSPTANLKLLTNVALQYPTPPPSAVQRKEKSLQILCDRFLNMYPLHGDGPIEIQLDSTATRLGVEKRRMYDIINILEAMQCAVHKRKNTYLWHGGSRLNSFLKMLKKQGEHLKLSEALRGKAPKPPAPKYKTLGVLAQRFLMLFLVEPPNTLINLEMAVRVLIDTSSKTKTVLSPEQQDRQHKSKVRRLYDIANVFISIGLIEKVSGNLILKKPVFKYVGPHNIKKYDKTCLNTPSPITPLSALDNQQRIPSCHVFTGRSKRKLEFTTPLSTKELKLGITTPPHTPSYKWDEILLVADMELTKINNGVVL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00967840;
- 90% Identity
- iTF_00794111;
- 80% Identity
- -