Edef004139.1
Basic Information
- Insect
- Erannis defoliaria
- Gene Symbol
- e2f7
- Assembly
- GCA_905404285.1
- Location
- FR990068.1:14114913-14118935[+]
Transcription Factor Domain
- TF Family
- E2F
- Domain
- E2F_TDP domain
- PFAM
- PF02319
- TF Group
- Helix-turn-helix
- Description
- This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 2.4e-22 2.2e-18 66.3 0.0 1 65 53 119 53 119 0.92 2 3 1.9 1.8e+04 -3.8 0.0 12 28 126 141 125 143 0.63 3 3 3.1e-17 3e-13 49.9 0.1 1 64 154 244 154 245 0.90
Sequence Information
- Coding Sequence
- ATGTATGAAGATGACAACATTACTTGTACGCCGAAGCGCTATGTGCTCACTGAAGTCACTAATTCGTCAAGCTATATTTCACCGACCGCTAACCTCAAGCTTCTGACTAATGTCGCGCTACACTACCCCACGCCGCCGCCGAGCGCGGCTCAACGCAAAGAAAAGTCTCTTCAGATATTGTGCGATAGGTTCCTCAACATCTATCCACTGTATGGTAATGGAACTGTGGAAATACAATTGGACACTACTGCAGCCAGGCTAGGCGTGGAAAAGCGACGAATGTATGATATAATCAACATACTCGAAGCCATGCAATGTGCTGTGCACAAGAGGAAAAACACATATCTATGGCATGGAGGAGCTCGGTTAAATGCTTTCTTAAAAATGCTAAAAAAACAAGGAGAGAACTTAAAACTGTCAGATGTCTTGCGAGGAAGAGCACCTAAACCACCAACACCAAAACATAAAACATTAGGAGTGTTGGCACAGAGATTCCTGATGCTCTTCTTGGTTGAACCACCTAATACATTGATAAACCTAGAGATGGCAGTGCGAGTGCTCATCGATACCTCCTGTAAGAACAGAACTACTCTGTCTCCAGAGCAGCAGGAGCGCCAACACAAGTCTAAAGTGAGGCGGCTATACGACATTGCCAACGTATTTATTTCTATTGGTCTCATAGAAAAGGTTTCCGGTAATTTGATATTAAAGAAACCAGTATTTAAATATGTAGGACCATACAACCCTAAAAAGGCTGATAAGATGGTAGCTTTACCGTCTCCAATAACACCGTTGACGGCATTAGATAATGAAAGAGCTGCCACATGTCATGTATTTGCCGGGAAGTCTAAACGGAAGCTGGAGTTTACAACCCCCACAACTTCCAAAGAACTGAAACTCGGCATCACCACTCCTCCTCCTACCCCTTCACATAAGTGGGATGAGATTTTGCTGGTGGCTGACATGGAACTGACTAGAATTAACAATGGCGTAATGTTGTGA
- Protein Sequence
- MYEDDNITCTPKRYVLTEVTNSSSYISPTANLKLLTNVALHYPTPPPSAAQRKEKSLQILCDRFLNIYPLYGNGTVEIQLDTTAARLGVEKRRMYDIINILEAMQCAVHKRKNTYLWHGGARLNAFLKMLKKQGENLKLSDVLRGRAPKPPTPKHKTLGVLAQRFLMLFLVEPPNTLINLEMAVRVLIDTSCKNRTTLSPEQQERQHKSKVRRLYDIANVFISIGLIEKVSGNLILKKPVFKYVGPYNPKKADKMVALPSPITPLTALDNERAATCHVFAGKSKRKLEFTTPTTSKELKLGITTPPPTPSHKWDEILLVADMELTRINNGVML
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00967840;
- 90% Identity
- iTF_00913402;
- 80% Identity
- -