Llea016588.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lithophane leautieri
Gene Symbol
Bcl11b
Assembly
GCA_949152455.1
Location
OX424474.1:15503396-15514348[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.073 5.7 8.3 8.6 1 23 265 287 265 287 0.96
2 12 9.4e-06 0.00073 20.5 1.9 2 23 295 316 294 316 0.95
3 12 0.08 6.2 8.2 0.3 1 23 320 342 320 342 0.97
4 12 0.00051 0.039 15.1 3.0 1 23 347 370 347 370 0.97
5 12 0.0015 0.12 13.6 0.3 3 23 376 397 375 397 0.96
6 12 0.0048 0.37 12.0 0.3 2 20 413 431 413 437 0.93
7 12 0.00053 0.042 15.0 0.1 3 23 447 468 447 468 0.95
8 12 0.0042 0.33 12.2 0.9 2 23 491 513 491 513 0.95
9 12 0.088 6.9 8.0 2.7 2 23 525 546 524 546 0.95
10 12 0.00021 0.017 16.3 4.9 1 23 552 574 552 574 0.99
11 12 2.6e-06 0.0002 22.3 0.3 1 23 580 602 580 602 0.98
12 12 0.00083 0.065 14.4 0.9 1 23 608 631 608 631 0.98

Sequence Information

Coding Sequence
atGGGAGACGTTCAAGTCTGCCGCATTTGTTTAAATACGGATGTTAAAATGCAGGACCTGTTGGCATACCCTTTAGAATCTTATTTTGCATCATTCATGATTGAAAGTAAGCCTCTAAACTTGCCGCCATATGCCTGCTATGAGTGTGCAGCACTTGCgaagaagttttatttatttagagagAAGTGTCTGCAGAGCCAGGGGCTGCTGTGTGGAATCATTGATCATTGTGGGAAGCTAACACGCCCAGCAATAAAATCGATTGCCAGAAAAAATCTCCTCACAGTTACAAATGCCACTATTATCAGCATTGAACAAGATCGCACAGCAAATTGTATCAGCATAGAAAGACCTGAGTTCATTGTAGAAGTTATCAAGAAAGAGGATCATGATGCAGTTGATGTTCCTGATCACATCAGTCTTCCTGATAATAGTTctagtgatgatgatgatgaatgtgaCAAGAAAATTCATGAAGTAGAGAAGGTTGAGGTTTCTGTGAAAATGGACATAGGTGAGGAGTCTGATGGTCCTGAGCTTTCTGAAACAAAAGTTGATACAGCAAAATTGCCTATAAAAACATCTCGAACAGCCCAGCCCAAGAAGCGAATAAGGCCCAAGAGCAGCCGTACTATGGTTGCTAAGCAAAGTCTACCCAAAGTTAAAAAGAAGGATGACACACAATGCAACGACCAGACTGATGATTTGATCAATGTTATAACTCTCTCGATTGAGGATCAGATAGAAGAGATGAACAAACGCAAGCTGTCATCCAACTACCTCGACTGTCCGTACAAGTGCCACCAGTGCTACAGGGGGTTCAACAACACGCACGCGTGGAAACATCACCTCACCAAACACTCGCCGAACCTGGGCGACATAGAGTGCAAAATCTGCAAATACAGGTTTAAAACGAAACGTAATCTGCAGAGACATGCCCTAAACCACGGGAAGAGATATGTGTGCAATTTATGTCCATACAACTCTAGTAATATAACTACTGTAAAGCAGCATCAAGGGTCACATAAGGGGGTCACGCATAAATGCAAGTTTTGTGATGAAGTATTCAATGTAAGAACGACGTACGTTAGTCACATGCGGATCAAGCATCCATCAGAAAATATCTGTGGGTTTTGTGGGTACTCCTTCTACAGCAAGCAAGGGCTCTTGGTACATAAGAACATGATGCACAAGGACATTGAATCAAAACAAGAAGAGAACACAGAAGAAGGTCCATATTGCCAAGATTGTGACGTCAAGTTCATATCGACAGAGGCTTACAAGAGACACATGGTGATGTCAGTGAAGCACACACGAAGTACGGACTCTATGAATGGGTGTCGTGTTTGCGGCGAGATGTTCACGGACCCTGAAGAGCTGCGTCTGCACAATCGTGAGGAGCATCCAAAGAAACAACCGAAACACTACAATTACCAACGGAAGAGTCAAGTTCGAACCAAATGGCCCGCCAAGTGTCAACATTGTCCAGAAGAATTTGCCACCCCGCGCGCATACTGGAACCATAACCGACTCAAGCATCCTGATAAGTATGAGCCAGTGCGGAAGAACTGCGTCTGTGATATATGCGGCAAGAGATACGCATGCAACGCCGTACTGTCTATGCACAAGCGCACCCACTTCGGGGAGCGTCCGTACAAATGCTCTCAGTGCGACAAGGCCTGCTTCTCTGCACACGACCTGCGCGTACATCAGCAGAAACATTCCGACACGCGACCCTTCCCCTGCAGCGTGTGCTCCCAAGCTTTCAAGCGGAAAGAAGCGCTGGAAAGGCATTTGAAAATCCATTCTGGCGACAATCCATACAAATGCGAGATTTGCGGTGTAGCGTTCGCCAAGTCTTGCACAAGAACACTTCACGTGCGCACCGTACATACTAAGGAACCACCGCCACCGCGGAAACGACGGAACAAGGTGAACAAATAA
Protein Sequence
MGDVQVCRICLNTDVKMQDLLAYPLESYFASFMIESKPLNLPPYACYECAALAKKFYLFREKCLQSQGLLCGIIDHCGKLTRPAIKSIARKNLLTVTNATIISIEQDRTANCISIERPEFIVEVIKKEDHDAVDVPDHISLPDNSSSDDDDECDKKIHEVEKVEVSVKMDIGEESDGPELSETKVDTAKLPIKTSRTAQPKKRIRPKSSRTMVAKQSLPKVKKKDDTQCNDQTDDLINVITLSIEDQIEEMNKRKLSSNYLDCPYKCHQCYRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLLVHKNMMHKDIESKQEENTEEGPYCQDCDVKFISTEAYKRHMVMSVKHTRSTDSMNGCRVCGEMFTDPEELRLHNREEHPKKQPKHYNYQRKSQVRTKWPAKCQHCPEEFATPRAYWNHNRLKHPDKYEPVRKNCVCDICGKRYACNAVLSMHKRTHFGERPYKCSQCDKACFSAHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK