Basic Information

Insect: Cerastis leucographa
Gene Symbol: Bcl11a
Assembly: GCA_963082945.1
Location: OY720363.1:2758571-2782741[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.034 3.9 9.3 8.7 1 23 269 291 269 291 0.96

2 12 9.5e-06 0.0011 20.5 1.9 2 23 299 320 298 320 0.95

3 12 0.081 9.1 8.2 0.3 1 23 324 346 324 346 0.97

4 12 0.0005 0.056 15.1 3.2 1 23 351 374 351 374 0.97

5 12 0.0016 0.18 13.5 0.2 3 23 380 401 379 401 0.96

6 12 0.013 1.4 10.7 0.1 2 20 417 435 417 437 0.93

7 12 0.00035 0.039 15.6 0.1 3 23 451 472 451 472 0.95

8 12 0.00041 0.047 15.4 1.6 2 23 495 517 495 517 0.96

9 12 0.032 3.6 9.4 2.1 2 23 529 550 528 550 0.96

10 12 0.00022 0.024 16.3 4.9 1 23 556 578 556 578 0.99

11 12 0.00012 0.013 17.1 0.3 3 23 586 606 584 606 0.98

12 12 0.00084 0.095 14.4 0.9 1 23 612 635 612 635 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.034	3.9	9.3	8.7	1	23	269	291	269	291	0.96
2	12	9.5e-06	0.0011	20.5	1.9	2	23	299	320	298	320	0.95
3	12	0.081	9.1	8.2	0.3	1	23	324	346	324	346	0.97
4	12	0.0005	0.056	15.1	3.2	1	23	351	374	351	374	0.97
5	12	0.0016	0.18	13.5	0.2	3	23	380	401	379	401	0.96
6	12	0.013	1.4	10.7	0.1	2	20	417	435	417	437	0.93
7	12	0.00035	0.039	15.6	0.1	3	23	451	472	451	472	0.95
8	12	0.00041	0.047	15.4	1.6	2	23	495	517	495	517	0.96
9	12	0.032	3.6	9.4	2.1	2	23	529	550	528	550	0.96
10	12	0.00022	0.024	16.3	4.9	1	23	556	578	556	578	0.99
11	12	0.00012	0.013	17.1	0.3	3	23	586	606	584	606	0.98
12	12	0.00084	0.095	14.4	0.9	1	23	612	635	612	635	0.98

Sequence Information

Coding Sequence: ATGGGAGACGTTCAAGTGTGCCGTATTTGTTTAAACATGGATGTAGAAATGTCTGACCTGTCTGCATATcctttacaaacttattttgcCTCATTGATGATAGAAAGTAAGCCTCTATACTCCAACTTGCCACCATATGCCTGTTATGAATGCTCAGCGCTTGTGAAGaaatttcatttattcagaGAAAAGTGTCTGCAGAGCCACGGTCTGCTGTGTGGAATAATTGATGAATGTGGGAAGTTAACACACGCAGCAATAAAATCAATACACAGAAAAAACCTCACAGCTACAAATGTCaccaatataagtttaaaagaaGATAACACAACAGACTGTATAAGCCTAGAAAGACCTGAATTTGTGGTAGAAGTTATCAAGAAAGAGGATCATGATGATATGGACATTCCTGATCATGTCAGTCCAGATAATAGTTCCaatgatgttgatgataatGATCAATGTGAGAAGAATGATAAGAAGAAAATTCATGAAGTGGAGAAGGTGGAGATTTCTGTGAAGATAGACATTGAAGAAGAGTCTGATGATCTTCAACTTCCCGAAACAACAGATGTACCAAAAGTGCCAATCAAAAGATCACGGTCAGCCCAGTCCAAGAAGGGAATACGAGCAAAGAGGACTCGCACTACAGTTGCTAAGAAGAGTTCAATTAAACTGAAGAAGGACGACACACAATGCGATGACCACACTGATGATTTGATTAATGTTATTACtttatcgCTTGACGAACAGTTAGAGGAGATGAAGAAACGCCAGCAGTCATCCAACTACCTCGAGTGTCCGTACAAGTGCCACCAATGCTACAAGGGGTTCAACAACACGCACGCCTGGAAACATCACCTCACCAAACACTCTCCGAACGTCGGTGATATAGAGTGCAAAATCTGCAAGTACAGGTTTAAAACGAAACGAAACCTGCAGAGACATGCCCTGAACCACGGGAAGAGATACGTCTGCAATTTATGTCCATACAACTCTAGTAATATAACTACTGTGAAGCAGCATCAAGGGTCACATAAGGGAGTCACGCACAAGTGCAAATTCTGTGATGAAGTTTTCAATGTAAGAACAACTTACGTCACTCACATGCGAATAAAACATCCGTCGGAGAATATTTGTGGTTTCTGTGGGTACTCGTTCTACAGCAAGCAAGGACTCGTCGTACATAAGAATATGATGCACAAGGAAGTTGAAGGAAAACAAGAAGAGAACACAGAGGAAGGTCCATACTGCGAGGATTGTGATGTCAAGTTCATATCAACGGAGGCGTACAAGAGGCATTTGGTAATGTCCGTCAAGCACACCAGGAGTACAGTCTCTATGAACGGGTGCAGGGTATGCGGCGAGGTGTTCACGGACCCTGAAGAGTTACGTCTGCACAATCGCGAGGAACATCCGAAGAAACAACCGCAGCATTACAATCATAATCGGAAGAGTCAAGTTCGGACGAAATGGCCTGCCAAGTGTCAACATTGTCCAGAAGAGTTTGCCACCCCGCGTTCATACTGGAAGCATTACCGACTCAAGCACCCTGACAACTATGAACCGGTGCGGAAGAACTGCGTCTGTGATATATGCGGCAAGAGATATGCGTGCAACGCCGTCCTAGAGCTGCACAAACGCACGCACTTCGGCGAGCGGCCGTACAAGTGCTCGCAGTGCGACAAGGCGTGCTTTTCCGCGCACGACCTGCGCGTGCACCAGCAGAAACACTCCGACACGCGCCCCTTCGGCTGCAGCCAGTGCGCGCAGGCCTTCAAGCGGAAGGAAGCGCTGGAACGGCATTTGAAAATTCATTCCGGCGACAATCCATATAAGTGTGAGATCTGCGGCGTAGCGTTCGCCAAGTCCTGCACGAGAACGCTCCACGTTCGCACCGTACATACTAAGGAACCTCCGCCGCCGCGCAAACGACGGAACAAGGTGACCAAGTAA
Protein Sequence: MGDVQVCRICLNMDVEMSDLSAYPLQTYFASLMIESKPLYSNLPPYACYECSALVKKFHLFREKCLQSHGLLCGIIDECGKLTHAAIKSIHRKNLTATNVTNISLKEDNTTDCISLERPEFVVEVIKKEDHDDMDIPDHVSPDNSSNDVDDNDQCEKNDKKKIHEVEKVEISVKIDIEEESDDLQLPETTDVPKVPIKRSRSAQSKKGIRAKRTRTTVAKKSSIKLKKDDTQCDDHTDDLINVITLSLDEQLEEMKKRQQSSNYLECPYKCHQCYKGFNNTHAWKHHLTKHSPNVGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCDEVFNVRTTYVTHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKEVEGKQEENTEEGPYCEDCDVKFISTEAYKRHLVMSVKHTRSTVSMNGCRVCGEVFTDPEELRLHNREEHPKKQPQHYNHNRKSQVRTKWPAKCQHCPEEFATPRSYWKHYRLKHPDNYEPVRKNCVCDICGKRYACNAVLELHKRTHFGERPYKCSQCDKACFSAHDLRVHQQKHSDTRPFGCSQCAQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00712221;
80% Identity: -