Basic Information

Insect: Lithophane semibrunnea
Gene Symbol: Bcl11a
Assembly: GCA_947363905.1
Location: OX376202.1:15199823-15209838[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.065 4.8 8.3 8.6 1 23 266 288 266 288 0.96

2 12 8.3e-06 0.00062 20.5 1.9 2 23 296 317 295 317 0.95

3 12 0.071 5.3 8.2 0.3 1 23 321 343 321 343 0.97

4 12 0.00045 0.033 15.1 3.0 1 23 348 371 348 371 0.97

5 12 0.0013 0.1 13.6 0.3 3 23 377 398 376 398 0.96

6 12 0.0043 0.32 12.0 0.3 2 20 414 432 414 438 0.93

7 12 0.00047 0.035 15.0 0.1 3 23 448 469 448 469 0.95

8 12 0.025 1.9 9.6 0.8 2 23 492 514 492 514 0.96

9 12 0.078 5.8 8.0 2.7 2 23 526 547 525 547 0.95

10 12 0.00019 0.014 16.3 4.9 1 23 553 575 553 575 0.99

11 12 2.3e-06 0.00017 22.3 0.3 1 23 581 603 581 603 0.98

12 12 0.00074 0.055 14.4 0.9 1 23 609 632 609 632 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.065	4.8	8.3	8.6	1	23	266	288	266	288	0.96
2	12	8.3e-06	0.00062	20.5	1.9	2	23	296	317	295	317	0.95
3	12	0.071	5.3	8.2	0.3	1	23	321	343	321	343	0.97
4	12	0.00045	0.033	15.1	3.0	1	23	348	371	348	371	0.97
5	12	0.0013	0.1	13.6	0.3	3	23	377	398	376	398	0.96
6	12	0.0043	0.32	12.0	0.3	2	20	414	432	414	438	0.93
7	12	0.00047	0.035	15.0	0.1	3	23	448	469	448	469	0.95
8	12	0.025	1.9	9.6	0.8	2	23	492	514	492	514	0.96
9	12	0.078	5.8	8.0	2.7	2	23	526	547	525	547	0.95
10	12	0.00019	0.014	16.3	4.9	1	23	553	575	553	575	0.99
11	12	2.3e-06	0.00017	22.3	0.3	1	23	581	603	581	603	0.98
12	12	0.00074	0.055	14.4	0.9	1	23	609	632	609	632	0.98

Sequence Information

Coding Sequence: ATGGGAGACGTTCAAGTCTGCCGCATTTGTTTAAATACGGATGTTAAAATGCAGGACCTGTCGGCATACCCTTTAGAATCTTATTTTGCATCATTCATGATTGAAAGTAAGCCACTATACACCAACTTGCCGCCATATGCCTGCTATGAGTGTGCAGCACTTGTGAAGAAGTTTTATTTATTTAGAGAGAAGTGTCTGCAGAGCCAGGGGCTGCTGTGTGGAATCATTGATCATTGTGGGAAGCTAACCCGCCCAGCAATAAAATCAATTGCCAGAAAAAATCTCCTCACAATTACAAATGCCACTACTATCAGCATTGAACAAGATAGCACAGCTAATTGTATCAGCATACAAAGACCTGAGTTCATTGTAGAAGTTATTAAGAAAGAGGACCATGATGATGTTGATGTTCCTGATCACATCAGTCTTCCTGATAATAGTTCTAGTGATGGTGATGATGAATGTGACAAGAAAATTCATGAAGTCGAGAAGGTTGAGGTTTCTGTGAAAATGGACATAGGCGAGGAGTCTGATGGTCCTGAGCTTTCTGAAACAAAAGCGGATACAGCAAAATTGCCTATAAAAAAAACTCGAACAGCCCAGCCCAAGAAGCGAATAAGACCCAAGAGGACTCGTACTATGGTTGCTAAGCAAAGTCCACCCAAAGTTAAGAAGGATGACACACAATGCAACAACCAGACTGATGATTTGATTAATGTTATAACTCTCTCGATTGAGGATCAGATAGAAGAGATGAACAAACGCAAGCTGTCATCCAACTACCTCGACTGTCCGTACAAGTGCCACCAGTGCTACAGGGGGTTCAACAACACGCACGCCTGGAAACATCACCTCACCAAACACTCGCCGAACCTGGGCGACATAGAGTGCAAAATCTGCAAATACAGGTTTAAAACGAAACGTAATCTGCAGAGACATGCCCTAAACCACGGGAAGAGATATGTGTGCAATTTATGTCCATACAACTCTAGTAATATAACTACTGTAAAGCAGCATCAAGGGTCACATAAGGGGGTCACGCATAAATGCAAATTTTGTGATGAAGTATTCAATGTAAGAACGACGTACGTTAGTCACATGCGGATCAAGCATCCATCAGAAAATATCTGCGGGTTTTGTGGGTACTCCTTCTACAGCAAGCAAGGGCTCTTGGTACATAAGAATATGATGCACAAGGACATTGAATCAAAACAAGAAAAGAACACGGATGAAGGTCCATACTGCCAAGATTGTGACGTCAAGTTCATATCGACAGAGGCGTACAAGAGACACATGGTGATGTCAGTGAAGCACACACGGAGTACAGACTCTATGAATGGGTGTCGTGTTTGCGGCGAGATGTTCACGGACCCTGAAGAGCTACGTCTGCACAATCGTGAGGAGCATCCTAGGAAACAACCGAAGCACTACAATTACCAACGGAAGAGTCAAGTTCGAACCAAATGGCCTGCCAAGTGTCAACATTGTCCAGACGAATTTGCCACCCCGCGCGCATATTGGAACCATTACCGACTCAAGCATCCTGATAAGTATGAGCCAGTGCGGAAGAACTGCGTTTGTGATATATGCGGCAAGAGATACGCATGCAACGCCGTCCTGTCTATGCACAAACGCACCCACTTCGGGGAGCGCCCGTACAAATGCTCTCAGTGCGACAAGGCCTGCTTCTCTGCGCACGACCTGCGCGTACATCAGCAGAAACATTCCGACACGCGACCCTTCCCCTGCAGCGTGTGCTCCCAAGCTTTCAAGCGGAAAGAAGCGCTGGAAAGGCATTTGAAAATCCATTCCGGCGACAATCCATATAAATGTGAGATTTGCGGCGTAGCGTTCGCCAAGTCTTGCACAAGAACACTTCACGTGCGCACCGTACATACTAAGGAACCACCGCCACCGCGCAAACGACGGAACAAGGTGAACAAATAA
Protein Sequence: MGDVQVCRICLNTDVKMQDLSAYPLESYFASFMIESKPLYTNLPPYACYECAALVKKFYLFREKCLQSQGLLCGIIDHCGKLTRPAIKSIARKNLLTITNATTISIEQDSTANCISIQRPEFIVEVIKKEDHDDVDVPDHISLPDNSSSDGDDECDKKIHEVEKVEVSVKMDIGEESDGPELSETKADTAKLPIKKTRTAQPKKRIRPKRTRTMVAKQSPPKVKKDDTQCNNQTDDLINVITLSIEDQIEEMNKRKLSSNYLDCPYKCHQCYRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLLVHKNMMHKDIESKQEKNTDEGPYCQDCDVKFISTEAYKRHMVMSVKHTRSTDSMNGCRVCGEMFTDPEELRLHNREEHPRKQPKHYNYQRKSQVRTKWPAKCQHCPDEFATPRAYWNHYRLKHPDKYEPVRKNCVCDICGKRYACNAVLSMHKRTHFGERPYKCSQCDKACFSAHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00121804;
80% Identity: -