Basic Information

Insect: Conistra vaccinii
Gene Symbol: Bcl11a
Assembly: GCA_948150665.1
Location: OX411334.1:20191837-20208242[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.066 5.2 8.3 8.6 1 23 276 298 276 298 0.96

2 12 8.5e-06 0.00068 20.5 1.9 2 23 306 327 305 327 0.95

3 12 0.072 5.7 8.1 0.3 1 23 331 353 331 353 0.97

4 12 0.00045 0.036 15.1 3.0 1 23 358 381 358 381 0.97

5 12 0.0014 0.11 13.5 0.2 3 23 387 408 386 408 0.96

6 12 0.0034 0.28 12.3 0.2 2 20 424 442 424 448 0.93

7 12 0.00047 0.038 15.0 0.1 3 23 458 479 458 479 0.95

8 12 0.00069 0.056 14.5 0.8 2 23 502 524 502 524 0.96

9 12 0.079 6.3 8.0 2.7 2 23 536 557 535 557 0.95

10 12 0.00019 0.015 16.2 4.9 1 23 563 585 563 585 0.99

11 12 2.3e-06 0.00018 22.3 0.3 1 23 591 613 591 613 0.98

12 12 0.00075 0.06 14.4 0.9 1 23 619 642 619 642 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.066	5.2	8.3	8.6	1	23	276	298	276	298	0.96
2	12	8.5e-06	0.00068	20.5	1.9	2	23	306	327	305	327	0.95
3	12	0.072	5.7	8.1	0.3	1	23	331	353	331	353	0.97
4	12	0.00045	0.036	15.1	3.0	1	23	358	381	358	381	0.97
5	12	0.0014	0.11	13.5	0.2	3	23	387	408	386	408	0.96
6	12	0.0034	0.28	12.3	0.2	2	20	424	442	424	448	0.93
7	12	0.00047	0.038	15.0	0.1	3	23	458	479	458	479	0.95
8	12	0.00069	0.056	14.5	0.8	2	23	502	524	502	524	0.96
9	12	0.079	6.3	8.0	2.7	2	23	536	557	535	557	0.95
10	12	0.00019	0.015	16.2	4.9	1	23	563	585	563	585	0.99
11	12	2.3e-06	0.00018	22.3	0.3	1	23	591	613	591	613	0.98
12	12	0.00075	0.06	14.4	0.9	1	23	619	642	619	642	0.98

Sequence Information

Coding Sequence: ATGGGAGACGTTCAAGTGTGCCGCATTTGTTTAAATACAGATGTTAAAATGCAGGACCTGTCCGCATACCCTTTAGAATCTTATTTTGCATCATTCATGATTGAAAGTAAGCCCCTATACACCAACATGCCGCCATATGCCTGCTATGAGTGTGCAGCACTTGTGAAGAAGTTTTATTTATTTAGAGAGAAGTGTCTGCAGAGCCAGGGGCTGCTGTGTGAGATCATTGATGACTTTGGGAAGGTAACAGATGCAGCAATAAAATCGATTGCCAGAAAAAATCTCCTCGTAGTTACAAAAGTCACTAATATCAGCATTGAACAAGATAACACAACAAATTGTATCAGCATAGACACGCTAAGAAGAAGCATAGAAAGACCTGAATTCATTGTAGAAGTTATCAAGAAAGAGGATCATGATGATGTTGATGTTCCTGATCACATCAGTCCTAGTCCTCATAATAGTTCTAGTGATGATGATGATGGGGAGAAGAAAAGTAAGAAGAAAATTCACGAAGTAGAGCAGGTTGAGGTTTCTGTGAAAATGGACATAGAGGAGTCTGATGGTCCTGAGCTTTCAGAAAGATCAGTTGATACAGCAAAATTGCCTTTAAGAAAGTCTCGAACAGCCCAGCCCAAGAAGCGAATAAGACCCAAGAGGACTCGTACTATGGTTGCTAAGCAGAGTCCACCCAAAGTTAAGAAGGATAACACACAATGCGACGACCAGACTGATGATTTGATCAATGTTATTACTCTCTCGATTGAGGATCAGATAGAAGAGATGAACAAACGCAAGCTGTCGTCCAACTACCTCGACTGTCCGTACAAGTGCCACCAGTGCTACAGGGGGTTCAACAACACGCACGCGTGGAAACATCACCTCACCAAACACTCGCCGAACCTCGGCGACATAGAGTGCAAAATCTGTAAGTACAGATTTAAAACGAAACGTAATCTGCAAAGACATGCCCTAAACCATGGGAAGAGATATGTGTGCAATTTATGTCCATACAACTCTAGTAATATAACTACTGTGAAGCAGCATCAAGGTTCACATAAGGGAGTCACGCATAAATGCAAGTTTTGTGATGAAGTATTCAATGTAAGAACGACGTACGTTAGTCACATGCGGATCAAACATCCATCAGAAAATATCTGCGGGTTTTGCGGGTACTCTTTCTACAGCAAGCAAGGGCTCGTGGTTCATAAGAATATGATGCACAAGGACATTGAATTAAAACAAGAAGAGAACACAGAAGAAGGTCCATACTGCGAAGATTGTGACGTCAAGTTCATATCGACGGAGGCTTACAAGAGACACATGGTGATGTCAGTGAAGCATACACGGAGTACAGACTCTATGAAAGGGTGTCGTGTTTGCGGCGAGATGTTCTCGGACCCTGAAGAGCTACGTCTGCACAATCGTGAGGAGCATCCTAAGAAACAACCGAAGCACTACAATTACCAGCGGAAGAGTCAAGTTCGAACCAAATGGCCCGCCAAGTGTCAACATTGTCCAGAAGAGTTTGCCACCCCTCGAGCATACTGGAACCATTACCGACTCAAGCATCCTGATAAGTACGAGCCAGTAAGGAAGAATTGCGTCTGTGATATATGCGGCAAGAGATACGCATGCAACGCCGTCCTGTCTATGCACAAACGCACCCACTTCGGGGAGCGGCCGTACAAATGCTCTCAATGCGACAAGGCCTGCTTCTCCGCGCACGACCTGCGCGTACATCAGCAGAAACATTCCGACACGCGGCCCTTCCCTTGCAGCGTGTGCTCCCAAGCTTTCAAGCGGAAAGAAGCGCTGGAAAGGCATCTGAAAATCCATTCCGGCGACAATCCATACAAATGTGAAATTTGTGGCGTAGCGTTCGCCAAGTCTTGCACAAGAACACTTCACGTGCGCACCGTACATACTAAGGAACCACCGCCACCGCGCAAACGACGGAACAAGGTGAACAAATAA
Protein Sequence: MGDVQVCRICLNTDVKMQDLSAYPLESYFASFMIESKPLYTNMPPYACYECAALVKKFYLFREKCLQSQGLLCEIIDDFGKVTDAAIKSIARKNLLVVTKVTNISIEQDNTTNCISIDTLRRSIERPEFIVEVIKKEDHDDVDVPDHISPSPHNSSSDDDDGEKKSKKKIHEVEQVEVSVKMDIEESDGPELSERSVDTAKLPLRKSRTAQPKKRIRPKRTRTMVAKQSPPKVKKDNTQCDDQTDDLINVITLSIEDQIEEMNKRKLSSNYLDCPYKCHQCYRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKDIELKQEENTEEGPYCEDCDVKFISTEAYKRHMVMSVKHTRSTDSMKGCRVCGEMFSDPEELRLHNREEHPKKQPKHYNYQRKSQVRTKWPAKCQHCPEEFATPRAYWNHYRLKHPDKYEPVRKNCVCDICGKRYACNAVLSMHKRTHFGERPYKCSQCDKACFSAHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00121804;
80% Identity: -