Basic Information

Insect: Gortyna flavago
Gene Symbol: Bcl11a
Assembly: GCA_963669345.1
Location: OY770140.1:2605538-2614116[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.074 6 8.3 8.6 1 23 265 287 265 287 0.96

2 12 9.6e-06 0.00078 20.5 1.9 2 23 295 316 294 316 0.95

3 12 0.081 6.6 8.2 0.3 1 23 320 342 320 342 0.97

4 12 0.00052 0.042 15.1 3.0 1 23 347 370 347 370 0.97

5 12 0.0016 0.13 13.5 0.2 3 23 376 397 375 397 0.96

6 12 0.014 1.1 10.6 0.2 2 20 413 431 413 437 0.93

7 12 0.00054 0.044 15.0 0.1 3 23 447 468 447 468 0.95

8 12 0.00079 0.064 14.5 0.8 2 23 491 513 491 513 0.96

9 12 0.09 7.3 8.0 2.7 2 23 525 546 524 546 0.95

10 12 0.00022 0.018 16.3 4.9 1 23 552 574 552 574 0.99

11 12 2.6e-06 0.00021 22.3 0.3 1 23 580 602 580 602 0.98

12 12 0.00085 0.069 14.4 0.9 1 23 608 631 608 631 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.074	6	8.3	8.6	1	23	265	287	265	287	0.96
2	12	9.6e-06	0.00078	20.5	1.9	2	23	295	316	294	316	0.95
3	12	0.081	6.6	8.2	0.3	1	23	320	342	320	342	0.97
4	12	0.00052	0.042	15.1	3.0	1	23	347	370	347	370	0.97
5	12	0.0016	0.13	13.5	0.2	3	23	376	397	375	397	0.96
6	12	0.014	1.1	10.6	0.2	2	20	413	431	413	437	0.93
7	12	0.00054	0.044	15.0	0.1	3	23	447	468	447	468	0.95
8	12	0.00079	0.064	14.5	0.8	2	23	491	513	491	513	0.96
9	12	0.09	7.3	8.0	2.7	2	23	525	546	524	546	0.95
10	12	0.00022	0.018	16.3	4.9	1	23	552	574	552	574	0.99
11	12	2.6e-06	0.00021	22.3	0.3	1	23	580	602	580	602	0.98
12	12	0.00085	0.069	14.4	0.9	1	23	608	631	608	631	0.98

Sequence Information

Coding Sequence: ATGGGAGACGTACAAGTGTGCCGCATTTGTTTAAATACGGATGTTAAAATGCAGGACCTGTCGGCATACCCTTTAGAATCTTATTTTGCATCATTAATGATTGAAAGTAAGCCTCTATACACCAACTTGCCCCCATATGCCTGCTATGAGTGCGCAGCACTTGTGaggaagttttatttatttagagacAAGTGTCTGCAGAGCCAGGGGCTGCTATGTGCAATAATTGATGGCTGTGGAAAGCTAACGCATACAGCTATAAAATCAATTGCCAGAAAAAATCTCCTCACAGTTACGAATGTCACTAATATCAGCATAGAACAAGATAACACAACAAATTATATCAGCACAGAAAGACCCGAGTTTGTTGTAGAAGTTATCAAAAAAGAGGATCACGATGATGTCGATGTTCCTGATCACATCAGCCCTGATAACAGTTCTAGTGATGCTGATGATGACTGTGAGAAGAAAATTCGCGAAGTAGAGAAGGTTGAGATTTCTGTGAAGGTGAACATTCAGGAGGAGTCTGATGACCCTGAgCTTTCTGAAACAATGGTTGATACAGCAAAATTGCCTATAAAAAAATCCCGAACAGCCCAGCCCAAGAAGCGAGTAAGACCCAAGAGGACTCGTACTATGGTTGCTAAGAAGAGTCCAGCCAAAGTTAAGAAGGATGACACACAATGTGAAGGTCAGACTGATGATTTGATCAACGTCATTACTCTCTCGATTGAGGATCAAATAGAAGAGATGAACAAACGGAAACAGTCGTCCAACTACCTTGACTGTCCGTACAAGTGTCACCAGTGCTACAGGGGGTTCAACAACACGCACGCGTGGAAACATCACCTTACCAAACACTCCCCGAACCTCGGCGACATAGAGTGCAAAATTTGCAAGTACAGGtttaaaacgaaacgcaatctTCAGAGACATGCCCTAAACCACGGAAAGAgatatgtttgtaatttatgtcCATACAACTCTagtaatatAACTACTGTGAAACAGCATCAAGGGTCACATAAGGGAGTCACGCATAAATGCAAGTTCTGTGACGAAGTTTTCAATGTAAGAACAACGTACGTCAGTCACATGCGAATCAAACATCCATCAGAAAACATCTGCGGGTTTTGTGGGTACTCATTCTACAGCAAGCAGGGGCTCGTGGTTCACAAGAATATGATGCACAAAGACATTGAAGCAAAACAAGAAGAGAACACAGAAGAAGGTCCTTACTGCGAAGATTGTGAAGTCAAATTCATATCGACGGAGGCGTACAAAAGACACATGGTCATGTCAGTCAAGCACACTCGAAGTACAGACTCTATGAACGGATGTCGTGTTTGCGGCGAGATGTTCACGGACCCTGAAGAGTTACGTCTTCACAATCGTGAGGAGCATCCTAAGAAACAACCGAAGCATTACAATTACCAACGGAAGAGTCAAGTTCGGACCAAATGGCCCGCCAAGTGTCAACATTGTCCAGAAGAATTCGCCACTCCGCGTGCATACTGGAACCATTACCGACTCAAGCATCCTGATAAGTACGAGCCAGTGCGGAAGAATTGCGTCTGTGATATATGCGGCAAGCGATACGCGTGCAACGCCGTCCTCTCAATGCACAAACGCACCCACTTCGGGGAACGTCCCTACAAATGCTCTCAATGCGACAAGGCCTGCTTCTCTGCGCACGACCTGCGCGTTCATCAGCAAAAACATTCCGACACAAGACCCTTCCCTTGCAGCGTGTGCTCCCAAGCTTTCAAGCGGAAAGAAGCGCTGGAAAGGCATTTGAAAATCCATTCTGGCGACAACCCATATAAGTGTGAGATTTGCGGAGTGGCTTTCGCCAAGTCTTGCACGAGAACGCTTCACGTGCGCACCGTACATACTAAGGAACCACCGCCGCCGCGCAAACGACGGAACAAGGTCAATAAGTAA
Protein Sequence: MGDVQVCRICLNTDVKMQDLSAYPLESYFASLMIESKPLYTNLPPYACYECAALVRKFYLFRDKCLQSQGLLCAIIDGCGKLTHTAIKSIARKNLLTVTNVTNISIEQDNTTNYISTERPEFVVEVIKKEDHDDVDVPDHISPDNSSSDADDDCEKKIREVEKVEISVKVNIQEESDDPELSETMVDTAKLPIKKSRTAQPKKRVRPKRTRTMVAKKSPAKVKKDDTQCEGQTDDLINVITLSIEDQIEEMNKRKQSSNYLDCPYKCHQCYRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKDIEAKQEENTEEGPYCEDCEVKFISTEAYKRHMVMSVKHTRSTDSMNGCRVCGEMFTDPEELRLHNREEHPKKQPKHYNYQRKSQVRTKWPAKCQHCPEEFATPRAYWNHYRLKHPDKYEPVRKNCVCDICGKRYACNAVLSMHKRTHFGERPYKCSQCDKACFSAHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00121804;
80% Identity: -