Basic Information

Insect: Atethmia centrago
Gene Symbol: Bcl11a
Assembly: GCA_905333075.2
Location: HG995370.1:27304228-27314928[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.082 13 8.3 8.6 1 23 269 291 269 291 0.96

2 12 1.1e-05 0.0016 20.5 1.9 2 23 299 320 298 320 0.95

3 12 0.097 15 8.1 0.3 1 23 324 346 324 346 0.97

4 12 0.00057 0.088 15.1 3.0 1 23 351 374 351 374 0.97

5 12 0.0018 0.28 13.5 0.2 3 23 380 401 379 401 0.96

6 12 0.0043 0.67 12.3 0.2 2 20 417 435 417 441 0.93

7 12 0.0006 0.093 15.0 0.1 3 23 451 472 451 472 0.95

8 12 0.00087 0.13 14.5 0.8 2 23 495 517 495 517 0.96

9 12 0.099 15 8.0 2.7 2 23 529 550 528 550 0.95

10 12 0.00024 0.037 16.3 4.9 1 23 556 578 556 578 0.99

11 12 3.6e-06 0.00056 22.0 0.2 1 23 584 606 584 606 0.98

12 12 0.00094 0.14 14.4 0.9 1 23 612 635 612 635 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.082	13	8.3	8.6	1	23	269	291	269	291	0.96
2	12	1.1e-05	0.0016	20.5	1.9	2	23	299	320	298	320	0.95
3	12	0.097	15	8.1	0.3	1	23	324	346	324	346	0.97
4	12	0.00057	0.088	15.1	3.0	1	23	351	374	351	374	0.97
5	12	0.0018	0.28	13.5	0.2	3	23	380	401	379	401	0.96
6	12	0.0043	0.67	12.3	0.2	2	20	417	435	417	441	0.93
7	12	0.0006	0.093	15.0	0.1	3	23	451	472	451	472	0.95
8	12	0.00087	0.13	14.5	0.8	2	23	495	517	495	517	0.96
9	12	0.099	15	8.0	2.7	2	23	529	550	528	550	0.95
10	12	0.00024	0.037	16.3	4.9	1	23	556	578	556	578	0.99
11	12	3.6e-06	0.00056	22.0	0.2	1	23	584	606	584	606	0.98
12	12	0.00094	0.14	14.4	0.9	1	23	612	635	612	635	0.98

Sequence Information

Coding Sequence: ATGGGAGACGTTCAAGTGTGCCGCATTTGTTTAAATACGAATGTTAAAATGCAGGACCTGTCGGCATACCCTTTAGAATCTTATTTTGCTACACTCATGATTGAAAGTAAGCCTCTATACTCCAACTTGCCGCCATATGCCTGTTATGAGTGCACAGCACTTGTGaagaagttttatttatttagagagAAGTGTCTGCAGAGCCAGGGGCTGCTGTGTGGAATCATTGATGATTGTGGGAAGTTGACATACACAGCTATACAATCGATTCCCAGAAAAAATCTCCTCACAATTACAAATGTCACGAATATCAGCATAGAACAAGATAGCACAGCAAATTGTATCGCCATAGAAAGACCTGAATTCATTGTAGAAGTTATCAAAAAAGAGGATCATGACGATGTTGATGTTCCTGATCACATCAGTGCTGATGATAGTTCTAgtgctgatgatgatgaatgtctAAAAAAAAGTAAGAAGAAAATTCACGAAGTAGAGAAGGTTGAGATTTCTGTGAAGACGGACATTCAGGAGGAGTCTGATGGGCCTGAGCTCTCTGAAACAATACTTGATATACCAAAATTGCCAATCAAAAAATCCCATACAGCCCAGCCCAAAAAGCGACTAAGACCCAAGAGAACTTGTACTACGGTTGTAAAGACGAGTCCAGCCAAAGTTAAGACGGATGACACACAATGCGACGACCAAACTGATGATTTGATCAATGTTATTACCCTGTCGATAGAGGATCAACTAGAAGAAATGAACAAACGCAAGGTGTCGTCGAACTATCTCGACTGTCCGTACAAGTGTCACCAGTGCTACAGGGGGTTTAACAACACGCACGCGTGGAAACATCACCTCACCAAACACTCTCCGAACCTTGGCGACATAGAGTGCAAAATCTGCAAGTACAGGTTTAAAACGAAACGCAATCTTCAAAGACATGCTCTAAACCACGGGAAGAGAtatgtttgtaatttatgtCCATACAACTCTAGTAATATAACTACTGTGAGGCAGCATCAAGGGTCACATAAGGGAGTCACGCACAAATGCAAGTTTTGTGACGAAGTTTTCAATGTAAGAACGACGTACGTTAGTCACATGCGAATCAAACATCCATCAGAGAATATTTGTGGGTTCTGTGGGTACTCATTCTACAGCAAACAAGGGCTCGTGGTACATAAGAATATGATGCACAAGGATCTTGAAGCAAAACAAGAAGAAAACACAGAAGCCGGTCCATATTGCGAAGATTGTGACGTCAAATTCATATCGACGGAGGCGTACAAGAGACACATGGTGATGTCAGTCAAGCACACGCGGAGTACTGACTCTATGAACGGGTGTCGTGTTTGCGGCGAGATGTTCACGGACCCTGAAGAGTTACGTCTGCACAACCGTGAGGAGCACCCTAAGAAACAACCGAAGCACTACAATTACCAACGGAAGAGCCAAGTTCGAACCAAATGGCCCGCAAAGTGTCAACATTGTCCAGAAGAATTTGCCACCCCGCGCGCATACTGGAACCATTACCGACTCAAGCATCCCGATAAGTACGAGCCAGTGCGGAAGAATTGCGTCTGTGATATATGCGGCAAGCGATACGCATGCAATGCCGTCCTCTCTATGCACAAACGGACCCACTTCGGGGAGCGTCCGTACAAGTGCTCTCAGTGCGACAAGGCCTGCTTCTCCGCGCACGACCTGCGCGTGCACCAGCAGAAACATTCCGACACGCGCCCCTTCCCCTGCGGCGAGTGCTCCCAAGCTTTCAAGCGGAAAGAAGCGCTGGAAAggcatttgaaaATCCATTCCGGCGACAACCCATATAAGTGTGAGATTTGCGGCGTAGCGTTCGCCAAGTCTTGCACGAGAACACTTCACGTACGCACCGTACATACTAAGGAACCACCGCCACCGCGCAAACGACGGAACAAAGTGAACAAATAA
Protein Sequence: MGDVQVCRICLNTNVKMQDLSAYPLESYFATLMIESKPLYSNLPPYACYECTALVKKFYLFREKCLQSQGLLCGIIDDCGKLTYTAIQSIPRKNLLTITNVTNISIEQDSTANCIAIERPEFIVEVIKKEDHDDVDVPDHISADDSSSADDDECLKKSKKKIHEVEKVEISVKTDIQEESDGPELSETILDIPKLPIKKSHTAQPKKRLRPKRTCTTVVKTSPAKVKTDDTQCDDQTDDLINVITLSIEDQLEEMNKRKVSSNYLDCPYKCHQCYRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVRQHQGSHKGVTHKCKFCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKDLEAKQEENTEAGPYCEDCDVKFISTEAYKRHMVMSVKHTRSTDSMNGCRVCGEMFTDPEELRLHNREEHPKKQPKHYNYQRKSQVRTKWPAKCQHCPEEFATPRAYWNHYRLKHPDKYEPVRKNCVCDICGKRYACNAVLSMHKRTHFGERPYKCSQCDKACFSAHDLRVHQQKHSDTRPFPCGECSQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00121804;
80% Identity: -