Basic Information

Insect: Lycophotia porphyrea
Gene Symbol: Bcl11a
Assembly: GCA_950005105.1
Location: OX465401.1:15436066-15449255[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.07 5.8 8.3 8.6 1 23 264 286 264 286 0.96

2 12 9e-06 0.00075 20.5 1.9 2 23 294 315 293 315 0.95

3 12 0.076 6.3 8.2 0.3 1 23 319 341 319 341 0.97

4 12 0.00048 0.04 15.1 3.0 1 23 346 369 346 369 0.97

5 12 0.0015 0.13 13.5 0.2 3 23 375 396 374 396 0.96

6 12 0.024 2 9.8 0.0 2 20 412 430 412 432 0.93

7 12 0.00094 0.078 14.2 0.1 3 23 446 467 446 467 0.95

8 12 0.00062 0.052 14.7 1.3 2 23 490 512 490 512 0.96

9 12 0.03 2.5 9.4 2.1 2 23 524 545 523 545 0.96

10 12 0.0024 0.2 12.9 4.8 1 23 551 573 551 573 0.99

11 12 2.5e-06 0.0002 22.3 0.3 1 23 579 601 579 601 0.98

12 12 0.00082 0.068 14.4 0.9 1 23 607 630 607 630 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.07	5.8	8.3	8.6	1	23	264	286	264	286	0.96
2	12	9e-06	0.00075	20.5	1.9	2	23	294	315	293	315	0.95
3	12	0.076	6.3	8.2	0.3	1	23	319	341	319	341	0.97
4	12	0.00048	0.04	15.1	3.0	1	23	346	369	346	369	0.97
5	12	0.0015	0.13	13.5	0.2	3	23	375	396	374	396	0.96
6	12	0.024	2	9.8	0.0	2	20	412	430	412	432	0.93
7	12	0.00094	0.078	14.2	0.1	3	23	446	467	446	467	0.95
8	12	0.00062	0.052	14.7	1.3	2	23	490	512	490	512	0.96
9	12	0.03	2.5	9.4	2.1	2	23	524	545	523	545	0.96
10	12	0.0024	0.2	12.9	4.8	1	23	551	573	551	573	0.99
11	12	2.5e-06	0.0002	22.3	0.3	1	23	579	601	579	601	0.98
12	12	0.00082	0.068	14.4	0.9	1	23	607	630	607	630	0.98

Sequence Information

Coding Sequence: ATGGGAGACGTACAAGTGTGtcgtatttgtttaaacatggaTGTAAAAATGCAGGATCTGTCCGCATATCCTCTAGAAACTTATTTTGCATCATTGATGATAGAAAGTAagCCCCTGTACACAAACTTGCCACCATATGCCTGTTACGAATGCTCAgcgcttgtgaaaaagttttatttattcagagaAAAATGTCTCCAGAGCCAGCGTCTGCTGTGTGGAATAATTGATGAATGTGGGAAGTTAACATGCACAGCAATCAAATTGATTCCCAGAAAAAATCTCCTCACAGTTACAAATGTCACCAACATAAGCATAGAAGAAGACACAACTGACTGCATCAGCCTAGAAAGACCTGAATTCGTGGTAGAAGTTATCAAAAAAGAGGATCACGATGATATTGACATTCCTGATCATATCAGTCCAGATAACAGTtccagtgatgatgatgatgaatgtgataagaatgataaaaagaaaattcatgAAGTGGAGAAGGTGGAGATTTCTGTGAAGATAGACATTGAAGAAGAGTCTGATGATCTTAAACTTCCCGAAACAACGGTTGATGTTCCAAAATTGCCAATCAAAAAATCCCGGACAGCCCAGTCCAAGAAGGGGGTAATGCCTAAGAGGACTCGCACTACGGTTGCTAAGAAGGTGAAGAAAAACGACACACAATGCGACGACCAGACTGATGACTTGATTAACGTGATTACTCTATCGCTTGAAGAACAGTTTGAAGAGATGAACAAACGCAAGCAATCATCCAACTACCTCGAGTGTCCGTACAAGTGCCACCAGTGCTACAGGGGGTTCAACAACACGCACGCCTGGAAACATCACCTCACCAAACACTCTCCGAACCTGGGCGACATAGAGTGCAAAATCTGCAAGTACAGGTTTAAAACGAAACGAAACCTTCAGAGACATGCCTTAAACCACGGGAAGAGATATGTCTGCAATTTATGTCCATACAACTCTAGTAACATAACAACTGTGAAGCAGCATCAAGGGTCACATAAGGGAGTTACGCACAAGTGCAAATTCTGTGATGAAGTTTTCAATGTAAGAACAACATACGTCAGTCACATGCGAATAAAACATCCATCGGAGAATATTTGTGGTTTCTGTGGGTACTCGTTCTACAGCAAGCAAGGACTCGTCGTACATAAGAATATGATGCACAAGGAACTTGAAGCAAAACAAGAAGAGAACGCAGAGGAAGGTCCATACTGCGGGGATTGTGACGTCAAGTTTATATCAACGGAGGCGTACAAGAGACATTTGGTCATGTCAGTCAAGCACACCAGGACTACAGTCTCTATGAACGGGTGTCGTGTTTGCGGCGAGATCTTTACAGACCCTGAGGAGTTACGTCTGCACAATCGTGAGGAGCATCCGAAGAAACAACCGAAGCATTACAATTATAATCGGAAGAGTCAAGTTCGGACGAAATGGCCTGCCAAGTGTCAACATTGTCCAGAAGAGTTTGCCACTCCTCGTTCGTACTGGAACCATTACCGACTCAAGCACCCTGACAAGTACGAGCCAGTGCGGAAGAATTGCGTCTGTGACATATGCGGCAAGCGATACGCGTGCAACGCCGTCCTGGAGCTGCACAAGCGCACGCACTTCGGGGAGCGCCCCTACAAGTGCTCGCGGTGCGACACGGCGTGCTTCTCCGCGCACGACCTGCGCGTACATCAGCAGAAACACTCCGACACTAGACCCTTTCCTTGCAGCGTGTGCTCACAGGCTTTCAAACGGAAAGAAGCGCTGGAAAGGCATTTGAAAATCCATTCCGGTGACAATCCATATAAGTGTGATATTTGCGGCGTAGCGTTCGCCAAGTCCTGCACGAGAACACTCCACGTTCGCACCGTACATACTAAGGAACCTCCGCCGCCGCGCAAACGACGGAACAAGGTGAACAAATAA
Protein Sequence: MGDVQVCRICLNMDVKMQDLSAYPLETYFASLMIESKPLYTNLPPYACYECSALVKKFYLFREKCLQSQRLLCGIIDECGKLTCTAIKLIPRKNLLTVTNVTNISIEEDTTDCISLERPEFVVEVIKKEDHDDIDIPDHISPDNSSSDDDDECDKNDKKKIHEVEKVEISVKIDIEEESDDLKLPETTVDVPKLPIKKSRTAQSKKGVMPKRTRTTVAKKVKKNDTQCDDQTDDLINVITLSLEEQFEEMNKRKQSSNYLECPYKCHQCYRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKELEAKQEENAEEGPYCGDCDVKFISTEAYKRHLVMSVKHTRTTVSMNGCRVCGEIFTDPEELRLHNREEHPKKQPKHYNYNRKSQVRTKWPAKCQHCPEEFATPRSYWNHYRLKHPDKYEPVRKNCVCDICGKRYACNAVLELHKRTHFGERPYKCSRCDTACFSAHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKIHSGDNPYKCDICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00712221;
80% Identity: -