Basic Information

Insect: Ochropleura plecta
Gene Symbol: Bcl11a
Assembly: GCA_905475445.1
Location: FR997737.1:2941437-2955397[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.084 10 8.1 8.8 1 23 272 294 272 294 0.96

2 12 9.3e-06 0.0011 20.5 1.9 2 23 302 323 301 323 0.95

3 12 0.079 9.5 8.2 0.3 1 23 327 349 327 349 0.97

4 12 0.0005 0.06 15.1 3.0 1 23 354 377 354 377 0.97

5 12 0.0016 0.19 13.5 0.2 3 23 383 404 382 404 0.96

6 12 0.018 2.2 10.1 0.1 2 20 420 438 420 440 0.93

7 12 0.00034 0.041 15.6 0.1 3 23 454 475 454 475 0.95

8 12 0.00065 0.078 14.7 1.3 2 23 498 520 498 520 0.96

9 12 0.028 3.4 9.6 2.6 2 23 532 553 531 553 0.96

10 12 0.00032 0.038 15.7 3.9 1 23 559 581 559 581 0.99

11 12 4.7e-06 0.00056 21.5 0.2 1 23 587 609 587 609 0.98

12 12 0.00083 0.099 14.4 0.9 1 23 615 638 615 638 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.084	10	8.1	8.8	1	23	272	294	272	294	0.96
2	12	9.3e-06	0.0011	20.5	1.9	2	23	302	323	301	323	0.95
3	12	0.079	9.5	8.2	0.3	1	23	327	349	327	349	0.97
4	12	0.0005	0.06	15.1	3.0	1	23	354	377	354	377	0.97
5	12	0.0016	0.19	13.5	0.2	3	23	383	404	382	404	0.96
6	12	0.018	2.2	10.1	0.1	2	20	420	438	420	440	0.93
7	12	0.00034	0.041	15.6	0.1	3	23	454	475	454	475	0.95
8	12	0.00065	0.078	14.7	1.3	2	23	498	520	498	520	0.96
9	12	0.028	3.4	9.6	2.6	2	23	532	553	531	553	0.96
10	12	0.00032	0.038	15.7	3.9	1	23	559	581	559	581	0.99
11	12	4.7e-06	0.00056	21.5	0.2	1	23	587	609	587	609	0.98
12	12	0.00083	0.099	14.4	0.9	1	23	615	638	615	638	0.98

Sequence Information

Coding Sequence: ATGGAAGATGTTCAAGTGTGtcgtatttgtttaaacatTGATGTAAAAATGCAGGACCTGTTTGCATATCCTTTGGAAACTTATTTCGCATCGTTGATGATAGAAAGTAAGCCTTTATACACCAACTTGCCGCCCTATGCCTGCTATGAATGCACAGCACTTTTgaagaagttttatttatttaggaaaaaGTGTCTGCAGACCCAGGGTCTGCTGTGTGGAATAATTGATGAATGTGGAAAGCTATCACATTCAGGGATAAAATCCATACCCAGAAAAAATCTCCTCACAATTACAAATGTCACAAATATAAGTATGGAAGTAGATATTACTACTGACTGTATCAGCCTAGAAAGACCAGAATTTGCTGTAGAAGTTATCAAAAAAGAGGATCATGATGATATTGACATTCCTGATCATGTCAGGCCAGATAATAGTTCCAGTaatgatgaagatgatgatgataacgaATGTGAGAAGaatgataagaagaaaaaacatgAAGTAGAGAAGGTGGAGATTTCTGTGAAGATGGACATTGAAGAAGAGTCTGATGATAATGAGCTTCCCGCAACAACAGTAGAAATACCAAAATTGCCAATAAAAAAATCCCGGACAACATCGTCCAAGGGTATCAGGCCAAATAGGACACGCACTACAGTTGCTAAGAAGAATTCAGCAAAAGCGAAGAAGGATGACACACATTGCGACGACCAGACTGATaatttgatcaatgttattacTTTGTCGCTTGAGGAACAGTTAGAAGAGATGAACAAACGCAGACAGTCATCCAACTACCTCGAGTGTCCATACAAGTGCCACCAGTGCTTCAGGGGGTTCAATAACACGCACGCCTGGAAACATCACCTCACTAAACACTCCCCGAACCTCGGTGACATAGAGTGCAAAATTTGTAAGTACAGGTTTAAAACGAAACGAAATCTTCAGAGACATGCCCTGAATCACGGGAAGAGATATGTCTGCAATTTATGTCCATATAACTCTAGCAATATAACCACAGTGAAACAGCATCAAGGCTCACATAAGGGAGTCACGCATAAATGTAAATTCTGTGATGAAGTTTTcaaTGTAAGAACAACATACGTCAGTCACATGCGCATAAAACACCCATCAGAGAATATTTGTGGCTTCTGTGGGTACTCATTCTACAGCAAGCAGGGACTCGTCGTTCATAAGAATATGATGCATAAAGAACTTGAAGCAAAACCAGATGAAAACGCAGAAGAAGGTCCATATTGCGAAGAGTGTGACGTTAAGTTCATATCGACTGAGGCGTACAAGAGACATTTGGTGATGTCAGTCAAACACACCAGGAATACAGTCTCTATGAACGGGTGCAGAGTGTGCGGCGAAGTGTTCACGGACCCTGAAGAGTTACGTCTGCACAACCGTGAGGAGCATCCCAAGAAACAACCGAAGCACTACAGTCATAATAGGAATAGTCAAGTTCGAAACAAATGGCCCGCCAAGTGTCAACATTGTCCAGAAGAATTCGCCACCCCACGTTCATACTGGAACCATTATCGACTAAAGCATCCCGATAAGTACGAACCGGTGCGGAAGAACTGCGTCTGTGATATATGCGGCAAGAGATACGCGTGTAACGCCGTCCTACAGCTGCACAAGCGCACGCACTTCGGGGAGCGTCCCTACAAGTGCGCTCAGTGCGACAAGGCGTGCTTCTCAGCGCACGACCTGCGCGTGCACCAGCAGAAGCACTCCGACACCCGGCCCTTCCCCTGCGGCGTGTGCTCGCAGGCTTTCAAGCGGAAAGAAGCGCTGGAACGGCATTTAAAAATCCATTCCGGCGACAATCCATACAAGTGTGAGATTTGCGGCGTAGCATTCGCCAAGTCTTGTACAAGGACGCTCCACGTAAGAACAGTACATACTAAGGAACCCCCGCCGCCGCGCAAACGACGCAACAAAGTGAACAAATAG
Protein Sequence: MEDVQVCRICLNIDVKMQDLFAYPLETYFASLMIESKPLYTNLPPYACYECTALLKKFYLFRKKCLQTQGLLCGIIDECGKLSHSGIKSIPRKNLLTITNVTNISMEVDITTDCISLERPEFAVEVIKKEDHDDIDIPDHVRPDNSSSNDEDDDDNECEKNDKKKKHEVEKVEISVKMDIEEESDDNELPATTVEIPKLPIKKSRTTSSKGIRPNRTRTTVAKKNSAKAKKDDTHCDDQTDNLINVITLSLEEQLEEMNKRRQSSNYLECPYKCHQCFRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKELEAKPDENAEEGPYCEECDVKFISTEAYKRHLVMSVKHTRNTVSMNGCRVCGEVFTDPEELRLHNREEHPKKQPKHYSHNRNSQVRNKWPAKCQHCPEEFATPRSYWNHYRLKHPDKYEPVRKNCVCDICGKRYACNAVLQLHKRTHFGERPYKCAQCDKACFSAHDLRVHQQKHSDTRPFPCGVCSQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00712221;
80% Identity: -