Basic Information

Insect: Agrotis exclamationis
Gene Symbol: Bcl11a
Assembly: GCA_950005045.1
Location: OX465434.1:19436467-19450174[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.087 12 8.1 8.8 1 23 273 295 273 295 0.96

2 12 9.6e-06 0.0013 20.5 1.9 2 23 303 324 302 324 0.95

3 12 0.082 11 8.2 0.3 1 23 328 350 328 350 0.97

4 12 0.003 0.41 12.7 3.5 1 23 355 378 355 378 0.97

5 12 0.0016 0.22 13.5 0.2 3 23 384 405 383 405 0.96

6 12 0.013 1.8 10.7 0.1 2 20 421 439 421 441 0.93

7 12 0.00069 0.095 14.7 0.1 3 23 455 476 455 476 0.95

8 12 0.00067 0.091 14.7 1.3 2 23 499 521 499 521 0.96

9 12 0.032 4.4 9.4 2.1 2 23 533 554 532 554 0.96

10 12 0.0016 0.22 13.5 4.7 1 23 560 582 560 582 0.99

11 12 0.00016 0.022 16.7 0.1 3 23 590 610 588 610 0.97

12 12 0.00085 0.12 14.4 0.9 1 23 616 639 616 639 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.087	12	8.1	8.8	1	23	273	295	273	295	0.96
2	12	9.6e-06	0.0013	20.5	1.9	2	23	303	324	302	324	0.95
3	12	0.082	11	8.2	0.3	1	23	328	350	328	350	0.97
4	12	0.003	0.41	12.7	3.5	1	23	355	378	355	378	0.97
5	12	0.0016	0.22	13.5	0.2	3	23	384	405	383	405	0.96
6	12	0.013	1.8	10.7	0.1	2	20	421	439	421	441	0.93
7	12	0.00069	0.095	14.7	0.1	3	23	455	476	455	476	0.95
8	12	0.00067	0.091	14.7	1.3	2	23	499	521	499	521	0.96
9	12	0.032	4.4	9.4	2.1	2	23	533	554	532	554	0.96
10	12	0.0016	0.22	13.5	4.7	1	23	560	582	560	582	0.99
11	12	0.00016	0.022	16.7	0.1	3	23	590	610	588	610	0.97
12	12	0.00085	0.12	14.4	0.9	1	23	616	639	616	639	0.98

Sequence Information

Coding Sequence: ATGGGAGACGTTCAAGTGTGtcgtatttgtttaaatattgatGTAAAAATGCAGGACCTTTCTGCATGCCCATTAGAATCTTATTTTGCGACATTTATGATAGAAAGTAAGCCATTATACACCAACTTGCCGCCATACGCCTGCTATGAGTGTGCAGCTTTAATGAagaagttttatttattcagaGAAAAGTGTTTGCAAAGCCAGGGTCGGCTATGTGAAATTATTGATGAATATGGGAAGTTAACACATACAGCGATAAAATCAATACCAAGAAAAAATCTCCTCACAACTTCAAATGTCACAAATATCAGTataatagaagaagaaaacacAACAGATTGTATCCACATAGAAAGACCTCAATTTGCTGTAGAGGTGATCAAAAAGGAGGATCATGATGATATTGACATTCCTGAACATATCAGTCCTGATAATAGTtccagtgatgatgatgatgatgatgaatgtgagAAGACTGGTAAGAAGAAAATTCATGAAATGGAGAAGGTTGAGATTTCTGTGAAGATGGATGTTGAAGGGGAGTTTGATGATCTTGAACTTCCCGAAACAACAGTTGATGTACCAAAGTTGCCAATCAAAAAATCTCGAATCTCAGCCCAGTCCAAGAAAGGAATAAGGCCAAAGAGGACTCGTGCGGCAGTTACTAAGAAGAGTTCTACTACTGTTAAAAACGATGACACGCAATGTGAGGACCAGAGTGATGATTTGATCAATGTTATCACTTTAACGCTCGAGGAGCAGTTAGAAGAGATGAACAAACGCAAGCAGTCGTCCAACTACCTGGAGTGTCCGTACAAGTGCCACCAGTGCTTTAGGGGCTTCAACAACACGCACGCCTGGAAACATCACCTTACTAAACATTCTCCGAACCTCGGCGACATTGAGTGCAAAATATGCAAGTACAGGTTTAAAACGAAACGGAATCTTCAAAGACATGCATTAAACCACGGGAAGAGATATGTCTGTAACTTATGTCCGTACAACTCTAGTAATATAACTACTGTGAAGCAGCATCAAGGTTCACATAAGGGAGTTACGCACAAGTGCAAATTCTGCAATGAAATTTTCAATGTAAGAACAACATACGTCAGTCATATGCGAATCAAACATCCCTCAGAGAATATTTGTGGCTTCTGTGGCTACTCATTCTACAGCAAACAAGGACTAGTGGTTCATAAGAATATGATGCACAAGGATCTTGAAgcaAAACAAGAAGAGAACACAGAAGAAGGTCCTTACTGTGAGGATTGTGACGTCAAGTTCATATCAACAGAAGCTTACAAAAGACACCTGGTCATGTCAGTTAAACACACTAGGAGTACCGACTCTATGAACGGGTGTCGAGTTTGTGGTGAGATTTTCACGGATCCTGAACAGTTACGTTTACACAATCGTGAAGAGCATCCTAAGAAACAACCGAAACACTACAATTATAATAGGAAGAGTCAAACACGAACAAAATGGCCTGCCAAGTGTCAACATTGTCCAGAAGAATTCGCCACCCCGCGTTCATACTGGAACCATTACCGTCTGAAACATCCTGACAAGTACGAGCCGGCGCGGAAGAACTGCGTCTGTGATATATGTGGCAAGAGATATGCTTGCAACGCCGTCCTAGAGCTCCACAAGCGCACGCACTTCGGCGAGCGTCCGTACAAGTGTTCTCAATGCGAGCGCGCCTGCTTCTCCGCACACGACCTGCGAGTGCACCAACAGAAGCACTCCGACAGCCGGCCCTACGGGTGCGGGGTGTGTGCACAGGCCTTCAAGAGGAAGGAGGCGCTCGAGAGGCATTtgaaaATCCACTCCGGCGACAACCCATATAAGTGCGAGATTTGTGGCGTAGCTTTCGCCAAGTCTTGTACGAGAACACTTCACGTCCGCACCGTTCATACTAAGGAGCCCCCACCACCGCGCAAACGACGGAACAAGATCAACAAATAA
Protein Sequence: MGDVQVCRICLNIDVKMQDLSACPLESYFATFMIESKPLYTNLPPYACYECAALMKKFYLFREKCLQSQGRLCEIIDEYGKLTHTAIKSIPRKNLLTTSNVTNISIIEEENTTDCIHIERPQFAVEVIKKEDHDDIDIPEHISPDNSSSDDDDDDECEKTGKKKIHEMEKVEISVKMDVEGEFDDLELPETTVDVPKLPIKKSRISAQSKKGIRPKRTRAAVTKKSSTTVKNDDTQCEDQSDDLINVITLTLEEQLEEMNKRKQSSNYLECPYKCHQCFRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKFCNEIFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKDLEAKQEENTEEGPYCEDCDVKFISTEAYKRHLVMSVKHTRSTDSMNGCRVCGEIFTDPEQLRLHNREEHPKKQPKHYNYNRKSQTRTKWPAKCQHCPEEFATPRSYWNHYRLKHPDKYEPARKNCVCDICGKRYACNAVLELHKRTHFGERPYKCSQCERACFSAHDLRVHQQKHSDSRPYGCGVCAQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKINK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906431;
90% Identity: iTF_00040159;
80% Identity: -