Dhaw001822.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila hawaiiensis
Gene Symbol
-
Assembly
GCA_037043685.1
Location
JBAMBA010000067.1:5857845-5861885[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 9.6e-05 0.0064 16.8 0.1 1 23 148 171 148 171 0.96
2 14 0.0015 0.1 13.1 2.9 2 23 220 242 216 242 0.89
3 14 0.013 0.87 10.1 0.9 1 23 358 381 358 381 0.93
4 14 0.16 11 6.7 5.5 2 23 430 452 429 453 0.95
5 14 0.0034 0.23 12.0 0.5 1 23 516 539 516 539 0.88
6 14 7.9 5.2e+02 1.4 0.0 2 13 558 569 557 574 0.81
7 14 0.00073 0.048 14.1 3.3 2 23 590 612 590 612 0.96
8 14 0.00083 0.055 13.9 0.1 1 23 727 750 727 750 0.95
9 14 3.2e-05 0.0021 18.3 0.2 1 23 799 822 799 822 0.94
10 14 0.0012 0.081 13.4 2.2 2 23 872 894 871 894 0.97
11 14 0.0025 0.17 12.4 1.4 1 23 981 1004 981 1004 0.91
12 14 0.051 3.4 8.3 2.3 1 21 1056 1076 1056 1077 0.95
13 14 0.033 2.2 8.9 0.6 3 23 1117 1140 1116 1140 0.96
14 14 6.3 4.2e+02 1.7 0.4 1 20 1158 1179 1158 1182 0.61

Sequence Information

Coding Sequence
ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGATGATGATGCGGATGAGCAGGAgactgctgatgatgatgttgatgctggGAAAGGACCTGAGCCAGATGACGATgccatatttgattttgaactgGAGCCAATTGTTAGCATTGCGGAACCCGACCCAGCGCCAAGACCAACTGTCCGATTGGCGCCACCAATGCCAGTAGCTCCGCCCGTTCGGCCCCAGCAGCATAATCTTCAGTCAACGGTTAGCTCCACCTCATCCTCCATGATGGGAGGTCGCGGTGGTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTATTGGAATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAATAAGCGGATTGCCATGCATAGCCGGGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAGGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAAGTGGTTGCCATGATGCGTGCCGGTGACGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGCGTCGAGCAGCGTACTCATGGTGCGTCTCGGTTCGGGCCGATGAGCTATGGACCGGTTCGTGACGACGATGATGGTATCGAGGTCAAGAATGAGCTGATGGACACGGAAGCAACGGCTGACGATGATGTGGTTGACGAACAGAATCGCAGCTTCAACCAGACAAAGAAGAAACGTATTAATCAGTCGGCCAACTCTGCAAACGCTGGCAAAGCCGACAACgacagtggcagtggcggcGGCGCTTCGGATATCTGCGAGGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATGAAGACGCTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCACGCACCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCGaagaggagcaggagcaacaaaCGGTCAGTGCCAGTGCCGGCGATGATGCTGACGATAACTCTGGCATCGGCAATGGCTGCGATGATGAGTCCCTCTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAACCGCATATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAATGCCTACGGCATTCAGAATGCTCAGCAACACCGGATTACTCATCTCCCCTACAAGGCATATGCGCGCTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTTGGCTATGAACCGCGCAATTCCGGTGCTGGAGGAGCGGCTGTCGGTGCAGGACAGAGCCAGGTAAAGTCCCAGTCAACGCCgcgcaaacaaattgttactGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCgccaaataacaataatgttaATGAGGAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACCAGCTGCACAAGAACACGCCAGTTGCCACCAGCTACTGcagctgcggttgctgctgctgctgctgctgctgctgctgccactacCTCCGCGTCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCCACGCAGGCGGCGCTTAAGACGCACATTAGCGAGGAGCATGATTTTATGGACACGCAGTATAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGAAGACGCCAGCGGCAGCGTCTGTGGCAGCTACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatttgtgcccCTCCTGCGGCAAGCCATATAAGACGCAATATGAGTGGCGTCGCCACATCAACGAGGAGCATAACTTCGATAAGCGgcaatatttgaatatgcGCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGGGCAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTCAGACATCTCCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGCGAAATACAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGATATGCCAGTCATGTCCGGCACGACGTCAGACTCGCCAAcgcctggcagcagcagtaacagtgCTCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCCATGCGACCCGCTGGTCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGTCCCGAGTGCAACAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGCCGGCAAGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAACGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCTTATCGCTCGTTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCGaaagcaaatgtttttcaagCATTTGAACCGTGACACAAATCGCTGCGACAGCGGAGATCATAGTAACGAGGAACACATCTCCGAGCAGCCGGAGGAGAGATCTTCGCCCGCATACGATGCATCTGATGCCGCCTCGTATCGTTTGCTGTGCCCGCAGTGCGGCGATAACttcagcaccagcaccaaaTCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGTAAGCTGGATGTGCTGCACATGTCCAAGCTGGGCGATGAGCTCTATCGCTGCGTGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCCTATGCCGCCTACATACGTTGCCAGCTGtgcgagcaacagcagccggatGAACTGGGCCATGGTCCCGTTGCGGCCGGGATGCACAGCATGTGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTAGTCGTCGATGTGGACGATAAGGAGAGCCACCCGATAGCGGTGGCAAGCAATGAGTCATCTGGCAATGGGTCATATATGCCGATGCCACTGCAAATGCTCCTCGACggcgatgaggatgaggacaGCCAAACGGCGGCAGCCAACAATGAGACTTCCGACAATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence
MEGMDLWTSMFSADFEEADAGPKSHSYADEFMGDDDADEQETADDDVDAGKGPEPDDDAIFDFELEPIVSIAEPDPAPRPTVRLAPPMPVAPPVRPQQHNLQSTVSSTSSSMMGGRGGAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFIGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRTHGASRFGPMSYGPVRDDDDGIEVKNELMDTEATADDDVVDEQNRSFNQTKKKRINQSANSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTMKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVSASAGDDADDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGAGGAAVGAGQSQVKSQSTPRKQIVTVANETYEIIYLDDEQSPPNNNNVNEENDFGEQMQADDDDYATSCTRTRQLPPATAAAVAAAAAAAAAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEEKTPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQYEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVGNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREIQPKPQNGYDTIKYKDKDMPVMSGTTSDSPTPGSSSNSARSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDHSNEEHISEQPEERSSPAYDASDAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLDVLHMSKLGDELYRCVDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLVVDVDDKESHPIAVASNESSGNGSYMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS